3 article(s) from Svoboda, Jan
The structure of the oxazolidine-2-one-containing drugs linezolid (1) and rivaroxaban (2).
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Overview of the chiral ligands that were used for the study of the asymmetric Henry reaction.
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Syntheses of aldehydes 15–20.
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Synthesis of linezolid (1) and rivaroxaban (2) from nitroaldols 24 or 26.
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Beilstein J. Org. Chem. 2022, 18, 438–445, doi:10.3762/bjoc.18.46
Synthesis of optically pure 4-phenylchroman-2-one .
Synthesis of (R)-tolterodine .
Catalytic cycle of the Pd(II)-catalysed 1,4-addition of organoboron reagents to enones [3,26,35].
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Enantioselective β-arylation of cyclohexanone .
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Application of L2/Pd(OAc)2 in the total synthesis of terpenes .
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Plausible catalytic cycle for the addition of phenylboronic acid to 2-cyclohexenone catalysed by L3...
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Microwave-assisted addition of phenylboronic acid to 2-cyclohexenone catalysed by L4/Pd2(dba)3·CHCl3...
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Plausible catalytic cycle of the addition of phenylboronic acid to 2-cyclohexenone catalysed by pal...
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Proposed catalytic cycle for the addition of phenylboronic acids to 2-cyclohexenone catalysed by Pd...
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Usage of addition reactions of boronic acids to various chromones in the syntheses of potentially a...
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Multigram-scale synthesis of ABBV-2222 .
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Application of the asymmetric addition of phenylboronic acid to a chromone derivative for the total...
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Plausible catalytic cycle for the addition of phenylboronic acid to 3-methyl-2-cyclohexenone cataly...
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Total syntheses of naturally occurring terpenoids [10,11].
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Use of the L9/Pd(TFA)2 catalytic system for the synthesis of intermediates of biologically active c...
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Usage of a Michael addition catalysed by L9/Pd(TFA)2 in the total synthesis of (–)-ar-tenuifolene .
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Synthesis of terpenoids by Michael addition to 3-methyl-2-cyclopentenone .
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Rh-catalysed isomerisation of 3-alkyl-3-arylcyclopentanones to 1-tetralones .
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Addition reaction of phenylboronic acid to 3-methyl-2-cyclohexenone catalysed by L9/Pd(TFA)2 in wat...
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Micellar nanoreactor PdL10c for the synthesis of flavanones .
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Plausible catalytic cycle for the desymmetrisation of polycyclic cyclohexenediones by the addition ...
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Attempt to use the catalytic system L2/Pd(TFA)2 for the addition of phenylboronic acid to 3-methyl-...
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Ring opening of an enantioenriched tetrahydropyran-2-one derivative as alternative strategy to line...
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Synthesis of biologically active compounds from addition products [14-16].
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Chiral 1,10-phenantroline derivative L15 as ligand for the Pd-catalysed addition reactions of pheny...
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The Rh-catalysed addition reaction of phenylboronic acid to a 3-substituted enone .
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Underdeveloped methodologies [14,15,65-67].
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Flowchart for the selection of the proper catalytic system.
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Beilstein J. Org. Chem. 2021, 17, 1048–1085, doi:10.3762/bjoc.17.84
The known synthetic strategies leading to 3-(aminomethylidene)oxindoles.
The possible intermediates and products occurring in the reactions of 3-bromooxindoles with thioben...
The R1 and R2 substitution influence on the isolated yields of products 5aa–ed.
The Eschenmoser coupling reaction of 3-bromooxindole (1a) with thioacetamides.
The synthesis of alternative 3-substituted oxindoles and their Eschenmoser coupling reaction with t...
Beilstein J. Org. Chem. 2021, 17, 527–539, doi:10.3762/bjoc.17.47
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