Syntheses and applications of furanyl-functionalised 2,2’:6’,2’’-terpyridines

• Jérôme Husson and
• Michael Knorr

Beilstein J. Org. Chem. 2012, 8, 379–389, doi:10.3762/bjoc.8.41

• . Unfortunately, when applied to the synthesis of furanyl-substituted tpy 12, this method leads to irreproducible results [19]. Even turning to barium hydroxide as a base (which is known to favour Michael additions [20]) did not improve the course of the reaction in a substantial manner. Therefore, basic alumina

• [19][21] was tested, since it is known to be an efficient promoter of aldol condensations and Michael additions under solvent-free conditions [22][23]. Nevertheless, the treatment of furanyl-substituted aldehydes 1, 3 and 15 did not yield the targeted diketo-intermediates, but instead the chalcones 5

Amines as key building blocks in Pd-assisted multicomponent processes

• Didier Bouyssi,
• Nuno Monteiro and
• Geneviève Balme

Beilstein J. Org. Chem. 2011, 7, 1387–1406, doi:10.3762/bjoc.7.163

• transformations, including aza-Michael additions, hydroaminations of alkynes, Buchwald–Hartwig aminations, and allylic aminations, thereby allowing the creation of several covalent bonds in a single operation. Imine derivatives are also of high synthetic value as they may act either as electrophilic or