One-pot preparation of substituted pyrroles from α-diazocarbonyl compounds

• Fernando de C. da Silva,
• Mauricio G. Fonseca,
• Renata de S. Rianelli,
• Anna C. Cunha,
• Maria C. B. V. de Souza and
• Vitor F. Ferreira

Beilstein J. Org. Chem. 2008, 4, No. 45, doi:10.3762/bjoc.4.45

• ][11], electronics [12], gas sensors for organic compounds [13], and as building blocks in many physiologically interesting natural products, such as alkaloids [14]. The classical methods of constructing pyrrole ring system include mainly Knorr or Paal–Knorr syntheses, which have been summarized in a

Synthesis of deep- cavity fluorous calix[4]arenes as molecular recognition scaffolds

• Maksim Osipov,
• Qianli Chu,
• Steven J. Geib,
• Dennis P. Curran and
• Stephen G. Weber

Beilstein J. Org. Chem. 2008, 4, No. 36, doi:10.3762/bjoc.4.36

• have included nanowires [3], self organized nanostructures [4] chiral supramolecular assemblies [5], as well as sensors for cations [6][7], anions [8] and neutral organic molecules [9]. The versatility of the calixarene scaffold is a result of its preorganized cavity [10], which consists of four

• recyclable reagents [18] to the total synthesis of natural products [19]. Fluorous compounds are the basis for highly selective ion sensors that show promise by virtue of their low level of biofouling [20]. Recently, it was shown that simple fluorous compounds act as molecular receptors for selective

• are locked in the cone conformation have been synthesized. These molecules are soluble in several fluorous solvents, and show promise as fluorescent sensors. Introducing the hydroxyl functionality onto these molecules provides a scaffold with a deep cavity and hydrogen bonding functional groups for

Beilstein Journal of Organic Chemistry

• Jonathan Clayden

Beilstein J. Org. Chem. 2005, 1, No. 1, doi:10.1186/1860-5397-1-1

• : para-biologies built, just like the original kind, out of organic chemistry. The synthesis of molecular motors, or sensors, of springs and levers makes possible this new molecular engineering at the nanometre scale for eventual uses which only the future will tell. Expanding scientific horizons are