Amine-linked diglycosides: Synthesis facilitated by the enhanced reactivity of allylic electrophiles, and glycosidase inhibition assays

• Ian Cumpstey,
• Jens Frigell,
• Elias Pershagen,
• Tashfeen Akhtar,
• Elena Moreno-Clavijo,
• Inmaculada Robina,
• Dominic S. Alonzi and
• Terry D. Butters

Beilstein J. Org. Chem. 2011, 7, 1115–1123, doi:10.3762/bjoc.7.128

• National de la Recherche Scientifique, 91198 Gif-sur-Yvette CEDEX, France Department of Organic Chemistry, Faculty of Chemistry, University of Seville, Prof. García González, 1, 41012 Seville, Spain Glycobiology Institute, Department of Biochemistry, Oxford University, South Parks Road, Oxford, OX1 3QU

• . Supporting Information File 214: 1H and 13C NMR spectra of compounds 18–27. Acknowledgements IC acknowledges the support of Vetenskapsrådet (the Swedish Research Council). TDB and DSA acknowledge the support of the Glycobiology Institute and Grant No. R01CA125642 from the National Cancer Institute for part

(Pseudo)amide-linked oligosaccharide mimetics: molecular recognition and supramolecular properties

• José L. Jiménez Blanco,
• Fernando Ortega-Caballero,
• Carmen Ortiz Mellet and
• José M. García Fernández

Beilstein J. Org. Chem. 2010, 6, No. 20, doi:10.3762/bjoc.6.20

• oligosaccharides is not yet efficient enough for generating oligosaccharide-based libraries that may be useful in the future for the discovery of new therapeutic drugs. Taking into account the increasing importance of glycobiology and the difficulties associated to the synthesis of carbohydrate-based libraries