Study on the total synthesis of velbanamine: Chemoselective dioxygenation of alkenes with PIFA via a stop-and-flow strategy

• Huili Liu,
• Kuan Zheng,
• Xiang Lu,
• Xiaoxia Wang and
• Ran Hong

Beilstein J. Org. Chem. 2013, 9, 983–990, doi:10.3762/bjoc.9.113

• , mediated by metals such as Os, Mn, Pd, Ru, Fe, and Ag [26][27][28][29][30][31][32][33][34][35][36][37]. On the other hand, the metal-free hypervalent iodine(III)-mediated reactions have recently enjoyed a renaissance attracting extensive investigations [38][39]. It is particularly interesting in the case

Organic synthesis using (diacetoxyiodo)benzene (DIB): Unexpected and novel oxidation of 3-oxo-butanamides to 2,2-dihalo-N-phenylacetamides

• Wei-Bing Liu,
• Cui Chen,
• Qing Zhang and
• Zhi-Bo Zhu

Beilstein J. Org. Chem. 2012, 8, 344–348, doi:10.3762/bjoc.8.38

• ; 3-oxo-N-phenylbutanamides; Introduction Hypervalent iodine(III) reagents [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18] have received much attention, as reflected by the plethora of publications and reviews [19][20][21][22][23]. This is due to their low toxicity, ready availability

Hypervalent iodine(III)-induced methylene acetoxylation of 3-oxo-N-substituted butanamides

• Wei-Bing Liu,
• Cui Chen,
• Qing Zhang and
• Zhi-Bo Zhu

Beilstein J. Org. Chem. 2011, 7, 1436–1440, doi:10.3762/bjoc.7.167

Shelf-stable electrophilic trifluoromethylating reagents: A brief historical perspective

• Norio Shibata,
• Andrej Matsnev and
• Dominique Cahard

Beilstein J. Org. Chem. 2010, 6, No. 65, doi:10.3762/bjoc.6.65

• family of hypervalent iodine(III)-CF3 reagents as mild electrophilic trifluoromethylating agents suitable for reactions with carbon- and heteroatom-centered nucleophiles. These reagents further demonstrated generality in trifluoromethylation of a wide range of nucleophiles including the

• , enamines, and thiolate anions with these reagents, albeit in low to moderate yields [28]. Neutral hypervalent iodine(III)–CF3 reagent Initial attempts by Yagupolskii and Umemoto to synthesize iodonium salts with a trifluoromethyl group were unsuccessful. Whilst iodonium salts including p

Benzyne arylation of oxathiane glycosyl donors

• Martin A. Fascione and
• W. Bruce Turnbull

Beilstein J. Org. Chem. 2010, 6, No. 19, doi:10.3762/bjoc.6.19

• with external alcohols would be easier to achieve if the phenyl sulfonium ion was formed with a less reactive counter ion. However, oxidation of 1-ABT in the presence of ketal 14 with NIS [33], or hypervalent iodine (III) with either bis(acetoxy)iodobenzene [PhI(OAc)2] [34] or bis(trifluoroacetoxy