Methodologies for the synthesis of quaternary carbon centers via hydroalkylation of unactivated olefins: twenty years of advances

• Thiago S. Silva and
• Fernando Coelho

Beilstein J. Org. Chem. 2021, 17, 1565–1590, doi:10.3762/bjoc.17.112

• initiator toward the alkyl halide to generate an alkyl radical and the Ni(II) complex (B) (Scheme 33). The reduction of B by the organosilane produces Ni(II) hydride (C), which complexes with the olefin to afford, after a β-migratory insertion, the alkyl–Ni complex (D) with anti-Markovnikov selectivity

Synthesis of six-membered silacycles by borane-catalyzed double sila-Friedel–Crafts reaction

• Yafang Dong,
• Masahiko Sakai,
• Kazuto Fuji,
• Kohei Sekine and
• Yoichiro Kuninobu

Beilstein J. Org. Chem. 2020, 16, 409–414, doi:10.3762/bjoc.16.39

• been demonstrated. Keywords: borane; cyclic compound; organosilane; sila-Friedel–Crafts; silylation; Introduction Six-membered silacyclic compounds, such as phenoxasilin and phenothiasilin derivatives, are attractive compounds for applications as organic electronic materials [1][2][3][4], ligands [5

Allylic cross-coupling using aromatic aldehydes as α-alkoxyalkyl anions

• Akihiro Yuasa,
• Kazunori Nagao and
• Hirohisa Ohmiya

Beilstein J. Org. Chem. 2020, 16, 185–189, doi:10.3762/bjoc.16.21

• , agrochemicals and bioactive natural products. Generally, α-alkoxyalkyl anions are presynthesized as stoichiometric organometallic reagents such as organolithium, organozinc, organocuprate, organostannane, organosilane and organoboron compounds [1][2][3][4][5][6]. Alternatively, we showed that easily available