Continuous flow photocyclization of stilbenes – scalable synthesis of functionalized phenanthrenes and helicenes

• Quentin Lefebvre,
• Marc Jentsch and
• Magnus Rueping

Beilstein J. Org. Chem. 2013, 9, 1883–1890, doi:10.3762/bjoc.9.221

• also tolerated, but nitro- and amino groups containing stilbenes showed low conversion or decomposition. Meta-substituted substrates gave inseparable regioisomers, and ortho-substitution led to low conversion. In the case of substrate 1e, a separable 1:1 mixture of regioisomers 2e and 2e’ was obtained

Mild and efficient cyanuric chloride catalyzed Pictet–Spengler reaction

• Ashish Sharma,
• Mrityunjay Singh,
• Nitya Nand Rai and
• Devesh Sawant

Beilstein J. Org. Chem. 2013, 9, 1235–1242, doi:10.3762/bjoc.9.140

• cyclized product in poor yield along with impurities [1][22]. In contrast, our methodology proved effective in catalyzing the condensation of tryptamine and electron-donating aldehydes. Interestingly, the ortho-substitution on benzaldehyde is also well tolerated. For instance, the condensation of 2

Synthesis and ring openings of cinnamate-derived N-unfunctionalised aziridines

• Alan Armstrong and
• Alexandra Ferguson

Beilstein J. Org. Chem. 2012, 8, 1747–1752, doi:10.3762/bjoc.8.199

• 4–6, 8, 10). Poor isolated yields were observed when conditions (B) were used on electron-poor substrates; this was attributed to the increased susceptibility to hydrolysis of the aziridine products. The increased steric demand posed by ortho substitution was found to have a detrimental effect on

The effect of the formyl group position upon asymmetric isomeric diarylethenes bearing a naphthalene moiety

• Renjie Wang,
• Shouzhi Pu,
• Gang Liu and
• Shiqiang Cui

Beilstein J. Org. Chem. 2012, 8, 1018–1026, doi:10.3762/bjoc.8.114

• hexane and PMMA films, whereas the molar absorption coefficients of diarylethenes 1–3 increased in order of meta < para < ortho substitution by the formyl group in hexane. The results were in agreement with those of the reported diarylethenes containing an electron-withdrawing cyano group [49], but were