Constrained thermoresponsive polymers – new insights into fundamentals and applications

• Patricia Flemming,
• Alexander S. Münch,
• Andreas Fery and
• Petra Uhlmann

Beilstein J. Org. Chem. 2021, 17, 2123–2163, doi:10.3762/bjoc.17.138

Automated high-content imaging for cellular uptake, from the Schmuck cation to the latest cyclic oligochalcogenides

• Rémi Martinent,
• Javier López-Andarias,
• Dimitri Moreau,
• Yangyang Cheng,
• Naomi Sakai and
• Stefan Matile

Beilstein J. Org. Chem. 2020, 16, 2007–2016, doi:10.3762/bjoc.16.167

• far exceeds the related tetrapeptide analogues with arginine or lysine residues. As a result, the gene transfection efficiency of 13 is better than that of polyethylenimine (PEI) with a large number of charges, which is one of the current standards in gene transfection. The uptake takes place through

Effects of solvent additive on “s-shaped” curves in solution-processed small molecule solar cells

• John A. Love,
• Shu-Hua Chou,
• Ye Huang,
• Guilllermo C. Bazan and
• Thuc-Quyen Nguyen

Beilstein J. Org. Chem. 2016, 12, 2543–2555, doi:10.3762/bjoc.12.249

• ITO/ZnO/PEIE/p-SIDT(FBTThCA8)2:PC71BM/MoO3/Al where PEIE refers to ethoxylated polyethylenimine. The cathode was cast from a sol–gel of zinc acetate, and thermally converted to ZnO in air as described in literature [69]. A thin (10 nm) layer of PEIE has been shown in the past to improve contact by

Carbohydrate PEGylation, an approach to improve pharmacological potency

• M. Eugenia Giorgi,
• Rosalía Agusti and
• Rosa M. de Lederkremer

Beilstein J. Org. Chem. 2014, 10, 1433–1444, doi:10.3762/bjoc.10.147

• ]. Mannose was also PEGylated in order to target drugs specifically to mannose receptors present in liver endothelial cells. Mannosyl PEGylated polyethylenimine (PEI) conjugates were synthesized either by direct coupling the mannose and the PEG chain to the PEI backbone (Figure 3A) or by attaching the

• peptides. Activated PEG derivatives for conjugation. Mannosyl PEGylated polyethylenimine for delivery systems. (A) Mannose and PEG are independently linked to the PEI backbone; (B) Mannose is attached to PEI via a PEG chain, adapted from [44]. PEGylated mannose derivatives, adapted from [45]. PEGylated

Hyperbranched polyethylenimine bearing cyclodextrin moieties showing temperature and pH controlled dye release

• Indra Böhm,
• Susanne Katharina Kreth and
• Helmut Ritter

Beilstein J. Org. Chem. 2011, 7, 1130–1134, doi:10.3762/bjoc.7.130

• modified, hyperbranched polyethylenimine (PEI-CD) was investigated. 5,8-Dichloro-1,4-dihydroxyanthraquinone (AQ-OH) was enclosed simply by ionic attraction between the phenolate groups of AQ-OH and the protonated amino groups of polyethylenimine (PEI). Additionally, the adamantyl moieties of 1,4-bis-N

• : anthraquinone; cyclodextrin; drug delivery; polyethylenimine; release; Introduction The development of novel materials and their use as drug delivery systems has gained increased interest in the last few decades [1][2][3]. In this context, certain stimuli responsive behaviors are required [4][5]. Hence, the

• ability to release molecules in response to temperature or pH change is an important feature of new biopharmaceutical compounds [6][7][8][9][10][11]. Hyperbranched polyethylenimine (PEI) is a promising material for medical applications due to its high biocompatibility [12][13]. Active drugs bearing