ROMP-Derived cyclooctene-based monolithic polymeric materials reinforced with inorganic nanoparticles for applications in tissue engineering

• Franziska Weichelt,
• Solvig Lenz,
• Stefanie Tiede,
• Ingrid Reinhardt,
• Bernhard Frerich and
• Michael R. Buchmeiser

Beilstein J. Org. Chem. 2010, 6, 1199–1205, doi:10.3762/bjoc.6.137

• -opening metathesis polymerization (ROMP); tissue engineering; Introduction Tissue engineering (TE), a sub-area of regenerative medicine, brings together diverse technologies and interdisciplinary fields such as biology, engineering, material and life sciences, polymer and inorganic chemistry [1][2][3

• materials are required [7][8][9][10][11][12]. Bone is a natural composite material, being composed of an inorganic compound (calcium hydroxyapatite) incorporated into an organic matrix (collagen) and thus resulting in a material, which possesses high stiffness and fracture toughness [13][14]. Ring-opening

• metathesis polymerization (ROMP) derived norborn-2-ene (NBE)-based monolithic materials have previously been successfully tested for both osseous and adipose cell growth [6]. However, it has also been reported that the mechanical properties, such as hardness, of such scaffold materials were quite low. Harder

The catalytic performance of Ru–NHC alkylidene complexes: PCy₃ versus pyridine as the dissociating ligand

• Stefan Krehl,
• Diana Geißler,
• Sylvia Hauke,
• Oliver Kunz,
• Lucia Staude and
• Bernd Schmidt

Beilstein J. Org. Chem. 2010, 6, 1188–1198, doi:10.3762/bjoc.6.136

• activity of these pyridine-NHC complexes. They were found to initiate ring opening metathesis polymerization reactions very rapidly [30][31] and show a certain preference for cross metathesis [32][33][34][35]. If the pyridine ring is attached to the alkylidene ligand [36], a latent catalyst results which

Miniemulsion polymerization as a versatile tool for the synthesis of functionalized polymers

• Daniel Crespy and
• Katharina Landfester

Beilstein J. Org. Chem. 2010, 6, 1132–1148, doi:10.3762/bjoc.6.130

• copolymerization of isoprene afforded low crystalline polymers. After Grubbs popularized water resistant catalysts for metathesis polymerizations, it became clear that metathesis could be also performed in aqueous heterophase systems. Claverie et al. studied the ring-opening metathesis polymerization (ROMP) in

Synthesis and crossover reaction of TEMPO containing block copolymer via ROMP

• Olubummo Adekunle,
• Susanne Tanner and
• Wolfgang H. Binder

Beilstein J. Org. Chem. 2010, 6, No. 59, doi:10.3762/bjoc.6.59

• achieved extensively via living polymerization methods. Thus, besides acyclic diene metathesis polymerization (ADMET) [2], ring opening metathesis polymerization (ROMP) [3][4][5] is another type of olefin metathesis polymerization that can be used for the synthesis of block copolymers. Early examples of

Ring opening metathesis polymerization-derived block copolymers bearing chelating ligands: synthesis, metal immobilization and use in hydroformylation under micellar conditions

• Gajanan M. Pawar,
• Jochen Weckesser,
• Siegfried Blechert and
• Michael R. Buchmeiser

Beilstein J. Org. Chem. 2010, 6, No. 28, doi:10.3762/bjoc.6.28

• N,N-dipyrid-2-ylacetamide and their use in hydroformylation reactions [9]. Here, we report on the immobilization of a Rh-N,N-dipyrid-2-ylacetamide-based catalyst on a soluble, amphiphilic, ring-opening metathesis polymerization- (ROMP) derived block copolymer and its use in hydroformylation [10