Inductive heating and flow chemistry – a perfect synergy of emerging enabling technologies

• Conrad Kuhwald,
• Sibel Türkhan and
• Andreas Kirschning

Beilstein J. Org. Chem. 2022, 18, 688–706, doi:10.3762/bjoc.18.70

• preferred route for large-scale production of syngas from biogas [29], while the latter is the main catalytic route [30]. The intrinsic problem with these processes is the extremely high temperature required, typically above 700 °C (ambient pressure) [27]. Since most such processes do not operate at ambient

A comprehensive review of flow chemistry techniques tailored to the flavours and fragrances industries

• Guido Gambacorta,
• James S. Sharley and
• Ian R. Baxendale

Beilstein J. Org. Chem. 2021, 17, 1181–1312, doi:10.3762/bjoc.17.90

Rhodium-catalyzed reductive carbonylation of aryl iodides to arylaldehydes with syngas

• Zhenghui Liu,
• Peng Wang,
• Zhenzhong Yan,
• Suqing Chen,
• Dongkun Yu,
• Xinhui Zhao and
• Tiancheng Mu

Beilstein J. Org. Chem. 2020, 16, 645–656, doi:10.3762/bjoc.16.61

• pressure, cheap ligand and low metal dosage could significantly improve the practicability in both chemical researches and industrial applications. Keywords: cost-effective ligand; industrial catalysis; reductive carbonylation; rhodium catalyst; syngas; Introduction The exploration of environmentally

• crucial for new practical applications. Syngas is a mixture of CO and H2, which is cheap, abundant and widely used in chemical industry productions [14][15][16]. In spite of its comprehensive utilization in industry, reactions involving CO are relatively seldom employed in fine chemicals syntheses. This

• 2, 3, 4, or 5 bar, the yield of benzaldehyde accordingly increased to 51%, 62% 81%, and 97%, respectively (Table 3, entries 2–5). However, further increasing the pressures did not lead to higher yields (Table 3, entries 6 and 7). After that, we examined the proportions of the syngas components on

The synthesis of active pharmaceutical ingredients (APIs) using continuous flow chemistry

• Marcus Baumann and
• Ian R. Baxendale

Beilstein J. Org. Chem. 2015, 11, 1194–1219, doi:10.3762/bjoc.11.134

• vacuum can enable the extraction of gaseous substances from a flow stream. This concept has since been studied in a variety of applications using for instance O3, CO, H2, CO2, O2, NH3 or syngas and has been reviewed very recently [84]. One noteworthy application of the tube-in-tube system by the Ley

Phosphinocyclodextrins as confining units for catalytic metal centres. Applications to carbon–carbon bond forming reactions

• Matthieu Jouffroy,
• Rafael Gramage-Doria,
• David Sémeril,
• Dominique Armspach,
• Dominique Matt,
• Werner Oberhauser and
• Loïc Toupet

Beilstein J. Org. Chem. 2014, 10, 2388–2405, doi:10.3762/bjoc.10.249

• candidates for hydroformylation studies. High-pressure NMR studies Upon subjecting complex 13 to a syngas (1:1 CO/H2 mixture) pressure of 40 bar at 80 °C in toluene-d8 (Scheme 7), the only species that was detected by high-pressure NMR and IR spectroscopy [44] was complex trans-[RhH(HUGPHOS-2)(CO)3] (14