Chemistry in flow systems III

  1. editorImage
  1. Editor: Prof. Andreas Kirschning
    Leibniz Universität Hannover

The third Thematic Series on flow chemistry demonstrates the emerging importance of transforming chemical synthesis in the laboratory from a classical batch approach to continuous processes by using micro- and miniaturized flow reactors. In the past two decades this technology has seen a dramatic increase of visibility. Considering an analyses of the accompanied developments in flow synthesis one has to acknowledge that the topic has shifted among different disciplines with a variety of intensities and focus. In the late eighties and nineties, the idea of miniaturising continuous chemical processes was mainly pursued by chemical engineers. In the late nineties, organic chemists from both industry and academia became involved in the use of microreactors and provided a myriad of synthetic examples.

See also the Thematic Series:
Chemistry in flow systems II
Chemistry in flow systems

See videos about flow chemistry at Beilstein TV.

Chemistry in flow systems III

  1. Andreas Kirschning
  • Editorial
  • Published 16 Aug 2013

Beilstein J. Org. Chem. 2013, 9, 1696–1697, doi:10.3762/bjoc.9.193

3D-printed devices for continuous-flow organic chemistry

  1. Vincenza Dragone,
  2. Victor Sans,
  3. Mali H. Rosnes,
  4. Philip J. Kitson and
  5. Leroy Cronin
  • Full Research Paper
  • Published 16 May 2013

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  • Supp. Info

  • Video

Beilstein J. Org. Chem. 2013, 9, 951–959, doi:10.3762/bjoc.9.109

Simple and rapid hydrogenation of p-nitrophenol with aqueous formic acid in catalytic flow reactors

  1. Rahat Javaid,
  2. Shin-ichiro Kawasaki,
  3. Akira Suzuki and
  4. Toshishige M. Suzuki
  • Full Research Paper
  • Published 14 Jun 2013

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  • Supp. Info

Beilstein J. Org. Chem. 2013, 9, 1156–1163, doi:10.3762/bjoc.9.129

  • Full Research Paper
  • Published 17 Jul 2013

Beilstein J. Org. Chem. 2013, 9, 1437–1442, doi:10.3762/bjoc.9.162

Controlled synthesis of poly(3-hexylthiophene) in continuous flow

  1. Helga Seyler,
  2. Jegadesan Subbiah,
  3. David J. Jones,
  4. Andrew B. Holmes and
  5. Wallace W. H. Wong
  • Full Research Paper
  • Published 25 Jul 2013

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  • Supp. Info

Beilstein J. Org. Chem. 2013, 9, 1492–1500, doi:10.3762/bjoc.9.170

  • Full Research Paper
  • Published 29 Jul 2013

Beilstein J. Org. Chem. 2013, 9, 1508–1516, doi:10.3762/bjoc.9.172

The rapid generation of isothiocyanates in flow

  1. Marcus Baumann and
  2. Ian R. Baxendale
  • Full Research Paper
  • Published 08 Aug 2013

Beilstein J. Org. Chem. 2013, 9, 1613–1619, doi:10.3762/bjoc.9.184

Gallium-containing polymer brush film as efficient supported Lewis acid catalyst in a glass microreactor

  1. Rajesh Munirathinam,
  2. Roberto Ricciardi,
  3. Richard J. M. Egberink,
  4. Jurriaan Huskens,
  5. Michael Holtkamp,
  6. Herbert Wormeester,
  7. Uwe Karst and
  8. Willem Verboom
  • Full Research Paper
  • Published 16 Aug 2013

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  • Supp. Info

Beilstein J. Org. Chem. 2013, 9, 1698–1704, doi:10.3762/bjoc.9.194

  • Full Research Paper
  • Published 26 Aug 2013

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  • Supp. Info

Beilstein J. Org. Chem. 2013, 9, 1745–1750, doi:10.3762/bjoc.9.201

  • Full Research Paper
  • Published 02 Sep 2013

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  • Supp. Info

Beilstein J. Org. Chem. 2013, 9, 1781–1790, doi:10.3762/bjoc.9.207

Flow Giese reaction using cyanoborohydride as a radical mediator

  1. Takahide Fukuyama,
  2. Takuji Kawamoto,
  3. Mikako Kobayashi and
  4. Ilhyong Ryu
  • Letter
  • Published 03 Sep 2013

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  • Supp. Info

Beilstein J. Org. Chem. 2013, 9, 1791–1796, doi:10.3762/bjoc.9.208

Ethyl diazoacetate synthesis in flow

  1. Mariëlle M. E. Delville,
  2. Jan C. M. van Hest and
  3. Floris P. J. T. Rutjes
  • Full Research Paper
  • Published 05 Sep 2013

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Beilstein J. Org. Chem. 2013, 9, 1813–1818, doi:10.3762/bjoc.9.211

  • Letter
  • Published 10 Sep 2013

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Beilstein J. Org. Chem. 2013, 9, 1837–1842, doi:10.3762/bjoc.9.214

  • Full Research Paper
  • Published 11 Sep 2013

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  • Supp. Info

Beilstein J. Org. Chem. 2013, 9, 1843–1852, doi:10.3762/bjoc.9.215

  • Full Research Paper
  • Published 17 Sep 2013

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  • Supp. Info

Beilstein J. Org. Chem. 2013, 9, 1883–1890, doi:10.3762/bjoc.9.221

One-step synthesis of pyridines and dihydropyridines in a continuous flow microwave reactor

  1. Mark C. Bagley,
  2. Vincenzo Fusillo,
  3. Robert L. Jenkins,
  4. M. Caterina Lubinu and
  5. Christopher Mason
  • Full Research Paper
  • Published 30 Sep 2013

Beilstein J. Org. Chem. 2013, 9, 1957–1968, doi:10.3762/bjoc.9.232

Microflow photochemistry: UVC-induced [2 + 2]-photoadditions to furanone in a microcapillary reactor

  1. Sylvestre Bachollet,
  2. Kimitada Terao,
  3. Shin Aida,
  4. Yasuhiro Nishiyama,
  5. Kiyomi Kakiuchi and
  6. Michael Oelgemöller
  • Letter
  • Published 04 Oct 2013

  • PDF

Beilstein J. Org. Chem. 2013, 9, 2015–2021, doi:10.3762/bjoc.9.237

Flow synthesis of a versatile fructosamine mimic and quenching studies of a fructose transport probe

  1. Matthew B. Plutschack,
  2. D. Tyler McQuade,
  3. Giulio Valenti and
  4. Peter H. Seeberger
  • Full Research Paper
  • Published 07 Oct 2013

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  • Supp. Info

Beilstein J. Org. Chem. 2013, 9, 2022–2027, doi:10.3762/bjoc.9.238

Temperature measurements with two different IR sensors in a continuous-flow microwave heated system

  1. Jonas Rydfjord,
  2. Fredrik Svensson,
  3. Magnus Fagrell,
  4. Jonas Sävmarker,
  5. Måns Thulin and
  6. Mats Larhed
  • Full Research Paper
  • Published 10 Oct 2013

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  • Supp. Info

Beilstein J. Org. Chem. 2013, 9, 2079–2087, doi:10.3762/bjoc.9.244

Flow synthesis of phenylserine using threonine aldolase immobilized on Eupergit support

  1. Jagdish D. Tibhe,
  2. Hui Fu,
  3. Timothy Noël,
  4. Qi Wang,
  5. Jan Meuldijk and
  6. Volker Hessel
  • Full Research Paper
  • Published 22 Oct 2013

  • PDF

Beilstein J. Org. Chem. 2013, 9, 2168–2179, doi:10.3762/bjoc.9.254

Micro-flow synthesis and structural analysis of sterically crowded diimine ligands with five aryl rings

  1. Shinichiro Fuse,
  2. Nobutake Tanabe,
  3. Akio Tannna,
  4. Yohei Konishi and
  5. Takashi Takahashi
  • Full Research Paper
  • Published 01 Nov 2013

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  • Supp. Info

Beilstein J. Org. Chem. 2013, 9, 2336–2343, doi:10.3762/bjoc.9.268

Synthesis of homo- and heteromultivalent carbohydrate-functionalized oligo(amidoamines) using novel glyco-building blocks

  1. Felix Wojcik,
  2. Sinaida Lel,
  3. Alexander G. O’Brien,
  4. Peter H. Seeberger and
  5. Laura Hartmann
  • Full Research Paper
  • Published 07 Nov 2013

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  • Supp. Info

  • Video

Beilstein J. Org. Chem. 2013, 9, 2395–2403, doi:10.3762/bjoc.9.276

  • Full Research Paper
  • Published 13 Nov 2013

Beilstein J. Org. Chem. 2013, 9, 2457–2462, doi:10.3762/bjoc.9.284

Investigating the continuous synthesis of a nicotinonitrile precursor to nevirapine

  1. Ashley R. Longstreet,
  2. Suzanne M. Opalka,
  3. Brian S. Campbell,
  4. B. Frank Gupton and
  5. D. Tyler McQuade
  • Full Research Paper
  • Published 20 Nov 2013

  • PDF

  • Supp. Info

Beilstein J. Org. Chem. 2013, 9, 2570–2578, doi:10.3762/bjoc.9.292

  • Full Research Paper
  • Published 17 Dec 2013

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Beilstein J. Org. Chem. 2013, 9, 2886–2897, doi:10.3762/bjoc.9.325

  • Review
  • Published 14 Feb 2014

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Beilstein J. Org. Chem. 2014, 10, 405–424, doi:10.3762/bjoc.10.38

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