Sustainable fabrication of 2D-based devices through reuse of substrates with microfabricated electrodes

• Ying Zhang,
• Yigit Sozen,
• Esteban Zamora-Amo,
• Thomas Pucher,
• Nuria Jiménez-Arévalo,
• Zdenek Sofer,
• Yong Xie and
• Andres Castellanos-Gomez

Beilstein J. Nanotechnol. 2026, 17, 818–827, doi:10.3762/bjnano.17.58

• , Spain Department of Inorganic Chemistry, University of Chemistry and Technology, Prague, Prague, Czech Republic School of Advanced Materials and Nanotechnology, Xidian University, 710071 Xi’an, China 10.3762/bjnano.17.58 Abstract Fabricating microelectronic devices for two-dimensional (2D) materials

Restorative potential of laser-synthesized silver nanoparticles with Salvia officinalis for periodontal disease treatment: an in vitro study

• Jelena Filipović Tričković,
• Sanja Živković,
• Bojana Ilić,
• Miloš Tošić,
• Jelena Marinković,
• Ana Valenta Šobot and
• Miloš Momčilović

Beilstein J. Nanotechnol. 2026, 17, 781–795, doi:10.3762/bjnano.17.55

• ; silver nanoparticles (AgNPs); Introduction Synthesis of silver nanoparticles (AgNPs) is a promising nanotechnology with numerous biomedical applications, especially in the field of tissue restoration and regeneration [1]. The most commonly used methods in AgNP synthesis are (i) chemical methods, which

• , contaminant-free strategy that integrates nanotechnology with plant-derived phytochemicals to achieve positive therapeutic effects relevant for periodontal therapy. Future work should be focused on in vivo validation, mechanistic insights, and the development of clinically translatable formulations for

Tailoring Ag–Pt nanoalloys through solid-state dewetting: structural and optical insights

• Marcin Łapiński,
• Piotr Okoczuk,
• Blaž Grobiša,
• Ewa Pawlikowska,
• Amelia Rozwadowska,
• Wojciech Sadowski and
• Barbara Kościelska

Beilstein J. Nanotechnol. 2026, 17, 748–759, doi:10.3762/bjnano.17.52

• Marcin Lapinski Piotr Okoczuk Blaz Grobisa Ewa Pawlikowska Amelia Rozwadowska Wojciech Sadowski Barbara Koscielska Institute of Nanotechnology and Materials Engineering, Advanced Materials Center, Gdansk University of Technology, ul. G. Narutowicza 11/12, 80-233 Gdańsk, Poland 10.3762/bjnano

• chemical composition of the nanostructures was confirmed using XPS. Measurements were carried out with a hemispherical XPS spectrometer (Argus, Omicron Nanotechnology) equipped with an Mg Kα X-ray source, operated at 15 keV and 300 W. XPS measurements were performed under ultra-high vacuum at room

Environmental applications of silver nanoparticles: state-of-the-art review and emerging trends

• Soni Prajapati,
• Akash Kumar and
• Ranjana Singh

Beilstein J. Nanotechnol. 2026, 17, 697–736, doi:10.3762/bjnano.17.49

• water is due to AgNPs’ multifunctional properties and colloidal/gel stability. The water treatment approach has undergone a substantial revolution with the emergence of nanotechnology. Furthermore, the application of AgNPs in air and soil pollution must be addressed. 3.2 Air applications Air pollution

Protein-based custom-designed molecular nanotraps for biomedical applications

• Devid Maniglio,
• Alice Marinangeli and
• Alessandra Maria Bossi

Beilstein J. Nanotechnol. 2026, 17, 683–687, doi:10.3762/bjnano.17.47

• imprinted polymers; natural polymers silk fibroin; SilMA; Introduction Molecular recognition is a cornerstone in biomedical nanotechnology; it is pivotal to applications ranging from drug delivery to sequestering and to sensing. Where traditional affinity systems, such as antibodies, fall short for

Cellulose as a photocatalyst support material: extraction, structural features, and environmental applications

• Yee Teng Lim,
• Nur Farhana Jaafar,
• Azizul Hakim Lahuri and
• Endang Tri Wahyuni

Beilstein J. Nanotechnol. 2026, 17, 635–652, doi:10.3762/bjnano.17.44

• are already being used across diverse sectors including packaging, construction, and electronics [63][64]. Research continues to focus on extracting cellulose primarily from plants such as wood, cotton, and agricultural residues and processing it through various nanotechnology-based methods to enhance

Towards targeted drugs and next generation of nanomedicines

• Anna Salvati,
• Silvia Giordani and
• Wolfgang J. Parak

Beilstein J. Nanotechnol. 2026, 17, 598–601, doi:10.3762/bjnano.17.41

• , Germany 10.3762/bjnano.17.41 Keywords: cellular uptake; drug delivery; intracellular trafficking; nanomedicine; nanoparticles; tumor microenvironment; Nanomedicine is dedicated to the application of nanotechnology in the medical field. Nanosized materials are intended for delivering drugs to their

• used for vaccination are composed of a complex mixture of different lipids, all of which have a particular function. Additionally, inorganic nanoparticles can be made with controlled size and shape out of many different materials. Nanotechnology has also made standardized characterization and quality

• , synthesis and functionalization of nanobiomaterials, nanotechnology applied to therapy and medical diagnostics, and pharmaceutical nanotechnology. The collected articles and contributions provide a broad overview on recent advances in the field within the aforementioned topics. Additionally, it includes

Probing tribological evolution in atomically thin MoS₂ at different scales

• Xingzhong Zeng and
• Miao Zhang

Beilstein J. Nanotechnol. 2026, 17, 586–597, doi:10.3762/bjnano.17.40

• factor limiting the performance and reliability of nanotechnology-enabled devices, including magnetic storage systems and micro/nanoelectromechanical systems (MEMS/NEMS) [1][2]. Unlike macroscale friction, nanoscale friction of two-dimensional (2D) materials exhibits unique size-dependent and interface

Laser–material interactions in liquids for the synthesis of nanomaterials: current status and perspectives

• Carlos Doñate Buendia,
• Bilal Gökce and
• Leonid V. Zhigilei

Beilstein J. Nanotechnol. 2026, 17, 571–575, doi:10.3762/bjnano.17.38

• –matter interactions; laser processing in liquids; In the ever-evolving landscape of materials science and nanotechnology, laser synthesis and processing of colloids (LSPC) has emerged [1] as a powerful and versatile technique for producing high-purity, surfactant-free nanoparticles from a wide range of

Advances in nanotechnology applied to natural products

• Douglas Dourado,
• Fábio Rocha Formiga,
• Éverton do Nascimento Alencar and
• Franceline Reynaud

Beilstein J. Nanotechnol. 2026, 17, 555–558, doi:10.3762/bjnano.17.36

• photochemical instability, (c) rapid metabolic degradation, (d) reduced permeability, (e) volatility, and (f) unpleasant organoleptic characteristics. These attributes have compromised the potential of natural products towards their extensive application in diverse fields [1]. In this context, nanotechnology

• , and enhance functional biological performance, often by improving stability and delivery [1]. Thus, the association between nanotechnology and natural products not only drives therapeutic innovation but also redefines the role of these compounds across multiple contemporary technological domains. In

• contributions in this thematic issue highlight the significant potential of nanotechnology to overcome limitations of natural products, thereby enabling a wide range of effective applications, as noted in this editorial. By covering a broad range of nanostructured systems, this collection reflects the diversity

Upcycling agroindustrial waste into graphene oxide supports for gold nanoparticles: toward sustainable nanomaterials

• Juan Marcos Castro-Tapia,
• Selene Acosta,
• Hiram Joazet Ojeda-Galván,
• Elsie Evelyn Araujo-Palomo,
• Edgar Giovanni Villabona-Leal and
• Mildred Quintana

Beilstein J. Nanotechnol. 2026, 17, 489–504, doi:10.3762/bjnano.17.32

• UV–vis, ATR-FTIR, XPS, XRD, and Raman measurements, complemented by TGA and TEM to assess optical properties, surface chemistry, and structural and morphological features. Additionally, gold nanoparticles (AuNPs) were photochemically deposited onto Agro-GO to evaluate its potential for nanotechnology

Defects and defect-mediated engineering of two-dimensional materials: challenges and open questions

• Arkady V. Krasheninnikov,
• Matthias Batzill,
• Anouar-Akacha Delenda,
• Marija Drndić,
• Chris Ewels,
• Katharina J. Franke,
• Mahdi Ghorbani-Asl,
• Alexander Holleitner,
• Ado Jorio,
• Ute Kaiser,
• Daria Kieczka,
• Hannu-Pekka Komsa,
• Jani Kotakoski,
• Manuel Längle,
• David Lamprecht,
• Yun Liu,
• Steven G. Louie,
• Janina Maultzsch,
• Thomas Michely,
• Katherine Milton,
• Anna Niggas,
• Hanako Okuno,
• Joshua A. Robinson,
• Marika Schleberger,
• Bruno Schuler,
• Alexander Shluger,
• Kazu Suenaga,
• Kristian S. Thygesen,
• Richard A. Wilhelm,
• E. Harriet Åhlgren and
• Carla Bittencourt

Beilstein J. Nanotechnol. 2026, 17, 454–488, doi:10.3762/bjnano.17.31

Nanoinformatics: spanning scales, systems and solutions

• Iseult Lynch,
• Diego S. T. Martinez,
• Kunal Roy and
• Georgia Melagraki

Beilstein J. Nanotechnol. 2026, 17, 423–427, doi:10.3762/bjnano.17.28

• Iseult Lynch Diego S. T. Martinez Kunal Roy Georgia Melagraki School of Geography, Earth and Environmental Sciences, University of Birmingham, Edgbaston, B15 2TT Birmingham, United Kingdom Brazilian Nanotechnology National Laboratory (LNNano), Brazilian Center for Research in Energy and Materials

• perspectives, and one review paper) that provide a snapshot of recent exciting developments in nanoinformatics, and is an output from the Beilstein Nanotechnology symposium [1] of the same name, held in October 2022. The advances presented are clustered around four key needs, including (i) prediction of

• , systems and solutions) for stimulating discussions. We also thank the editorial team of the Beilstein Journal of Nanotechnology, especially the support from Dr. Barbara Hissa and Dr. Lasma Gailite for the completion of this Thematic Issue. Funding Funding from the Horizon 2020 RISE project CompSafeNano

Biomimetic nanoparticles in cancer photodynamic therapy: a review of targeted delivery systems and therapeutic outcomes

• Valentina I. Gorbacheva,
• Alexey S. Grabovoy,
• Polina S. Marukhina,
• Anastasiia O. Syrocheva and
• Ekaterina P. Kolesova

Beilstein J. Nanotechnol. 2026, 17, 396–422, doi:10.3762/bjnano.17.27

• that combine imaging and therapy, and the challenges that remain for translating these technologies into clinical practice. By merging principles of biomimicry with nanotechnology, BNPs offer a promising new approach to more precise and effective cancer treatments tailored to individual patients

• energy to molecular oxygen or other substrates, generating cytotoxic ROS [17]. Historically, PDT relied on organic molecules, either naturally derived or synthetically produced, but since the early 21th century, advancements in nanotechnology have revealed the photosensitizing capabilities of

Beam shaping techniques for pulsed laser ablation in liquids: Unlocking tunable control of nanoparticle synthesis in liquids

• Sergio Molina-Prados,
• Nadezhda M. Bulgakova,
• Alexander V. Bulgakov,
• Jesus Lancis,
• Gladys Mínguez Vega and
• Carlos Doñate-Buendia

Beilstein J. Nanotechnol. 2026, 17, 309–342, doi:10.3762/bjnano.17.22

• industrially available picosecond laser sources, still requiring high power sources (100 W) but removing the requirement for high repetition rate and faster scanning speeds [55]. PLAL-produced nanomaterials have broad applications across different nanotechnology fields, including X-ray radiotherapy [62], boron

Advancing nanolithography: a comprehensive review of materials for local anodic oxidation with AFM

• Matteo Lorenzoni

Beilstein J. Nanotechnol. 2026, 17, 275–291, doi:10.3762/bjnano.17.19

• provide a comprehensive understanding of material selection in LAO and its implications for advancing nanotechnology. Keywords: local anodic oxidation; nanofabrication; scanning probe lithography; Review 1 Introduction Advancements in nanotechnology have led to the development of numerous nanoscale

• implemented through a dual-pass technique or by controlling the electronic and ionic contributions to the total current [17][18]. While dynamic mode LAO does not eliminate tip wear [19], it significantly reduces its impact. As new materials continue to emerge in the field of nanotechnology, this review also

Durable antimicrobial activity of fabrics functionalized with zeolite ion-exchanged nanomaterials against Staphylococcus aureus and Escherichia coli

• Perla Sánchez-López,
• Kendra Ramirez Acosta,
• Sergio Fuentes Moyado,
• Ruben Dario Cadena-Nava and
• Elena Smolentseva

Beilstein J. Nanotechnol. 2026, 17, 262–274, doi:10.3762/bjnano.17.18

• nanotechnology has expanded into different areas of science, including physics, chemistry, biology, and medicine, over the past few decades [1][2]. Recently, nanoparticles (NPs), nanomaterials, and nanocomposites have been applied in various fields, including medicine and biotechnology, to reduce the recurrence

• of infections [3][4]. In this context, nanotechnology and nanomaterials offer a new alternative to combat pathogens such as viruses and bacteria. Metal NPs have intrinsic manipulatable properties that make them useful in a wide variety of research fields, including biomedicine. Different types of NPs

• that ZnO possesses unique antibacterial, antimicrobial, and antifungal properties, making it effective against both Gram-positive and Gram-negative bacteria [19][20]. Recently, the application of nanotechnology has been extended to textiles. Fabrics functionalized with nanoparticles, also known as

Micro- and nanoscale effects in biological and bioinspired materials and surfaces

• Thies H. Büscher,
• Rhainer Guillermo Ferreira,
• Manuela Rebora and
• Stanislav N. Gorb

Beilstein J. Nanotechnol. 2026, 17, 214–217, doi:10.3762/bjnano.17.14

• inspiration from biological solutions for technology [3]. By studying multiscale structures and mechanisms in biological systems, biomimetics enables the translation of the fundamental principles into technological solutions for practical uses. In this context, bioinspired nanotechnology plays a vital role in

• generalizing nanoscale properties and processes in biology to engineer functional surfaces and interfaces across different scales. In May 2023, the Beilstein Nanotechnology Symposium titled “Functional Micro- and Nanostructured Surfaces: from Biology to Biomimetics” brought together a diverse group of

• discussions and collaborations from this symposium led to the motivation of vigorously representing this area in the Beilstein Journal of Nanotechnology, resulting in more than just one thematic issue showcasing novel research in this field. Emerging from this event, a first thematic issue "Biomimetics and

Safe and sustainable by design with ML/AI: A transformative approach to advancing nanotechnology

• Georgia Melagraki

Beilstein J. Nanotechnol. 2026, 17, 176–185, doi:10.3762/bjnano.17.11

• Georgia Melagraki Hellenic Military Academy, Vari, Greece 10.3762/bjnano.17.11 Abstract Nanotechnology is revolutionizing different sectors such as medicine, energy, defence, and environmental science by enabling the development of materials and technologies with exceptional precision and

• efficiency. From advanced drug delivery systems to clean energy solutions, the applications of nanotechnology are diverse and transformative. However, these innovations are accompanied by complex challenges regarding safety and sustainability for both the nanoscale materials themselves and for the products

• materials before producing them. This perspective article highlights how ML and AI are driving the evolution of SSbD in nanotechnology, focussing on predictive toxicology, materials informatics, lifecycle analysis, and the pivotal role of digital twins. It also explores current challenges, emerging

From shield to spear: Charge-reversible nanocarriers in overcoming cancer therapy barriers

• Madhuri Yeduvaka,
• Pooja Mittal,
• Ameer Boyalakuntla,
• Usman Bee Shaik,
• Himanshu Sharma,
• Thakur Gurjeet Singh,
• Siva Nageswara Rao Gajula and
• Lakshmi Vineela Nalla

Beilstein J. Nanotechnol. 2026, 17, 159–175, doi:10.3762/bjnano.17.10

• , drug resistance, and poor tumour selectivity. In response to these limitations, nanotechnology-based drug delivery systems have gained prominence for enhancing solubility, improving molecular stability, enabling controlled drug release, and prolonging systemic circulation, offering superior therapeutic

• pressing need for innovative solutions. An example would be smart nanocarrier drug delivery systems that enhance targeting precision and mitigate adverse effects [9][10]. Nanotechnology-based drug delivery systems have revolutionised cancer treatment by improving drug solubility, stability, and

Influence of surface characteristics on the in vitro stability and cell uptake of nanoliposomes for brain delivery

• Dushko Shalabalija,
• Ljubica Mihailova,
• Nikola Geskovski,
• Andreas Zimmer,
• Otmar Geiss,
• Sabrina Gioria,
• Diletta Scaccabarozzi and
• Marija Glavas Dodov

Beilstein J. Nanotechnol. 2026, 17, 139–158, doi:10.3762/bjnano.17.9

• characteristics; Introduction Advancements in nanotechnology and the use of nanoliposomes (NLs) as carriers for targeted delivery and controlled release of active components (AC) show promise in addressing multiple pathologies associated with neurodegenerative diseases like Alzheimer's disease (AD) [1]. It is

Development and in vitro evaluation of liposomes and immunoliposomes containing 5-fluorouracil and R-phycoerythrin as a potential phototheranostic system for colorectal cancer

• Raissa Rodrigues Camelo,
• Vivianne Cortez Sombra Vandesmet,
• Octavio Vital Baccallini,
• José de Brito Vieira Neto,
• Thais da Silva Moreira,
• Luzia Kalyne Almeida Moreira Leal,
• Claudia Pessoa,
• Daniel Giuliano Cerri,
• Maria Vitória Lopes Badra Bentley,
• Josimar O. Eloy,
• Ivanildo José da Silva Júnior and
• Raquel Petrilli

Beilstein J. Nanotechnol. 2026, 17, 97–121, doi:10.3762/bjnano.17.7

• that approximately half of metastatic CRC cases are resistant to 5-FU treatments, contributing to decrease the survival rate of patients [5]. In this context, nanotechnology has emerged as a promising therapeutic strategy for cancer treatment. Nanostructured drug delivery systems enable preferential

Missing links in nanomaterials research impacting productivity and perceptions

• Santosh K. Tiwari and
• Nannan Wang

Beilstein J. Nanotechnol. 2025, 16, 2168–2176, doi:10.3762/bjnano.16.149

• of scientific progress, nanotechnology remains underutilized in public-facing applications. A major issue is the limited engagement of leading tech industries in developing nanotechnology-based products, prompting concerns about tangible societal and industrial outcomes. Far away, funding challenges

• productive technologies like generative AI, machine learning, and related progress, nanotechnology has not achieved autonomous societal integration. The author argues that without a unified, transparent, and science-driven global regulatory framework, the transformative potential of nanotechnology will

• technology to catch up with his ideas, his foresight catalyzed a profound shift in the way scientists approached the material world. What was once philosophical became increasingly feasible and eventually tangible. Since then, various aspects of nanoscience and nanotechnology have evolved, ranging from the

Microplastic pollution in Himalayan lakes: assessment, risks, and sustainable remediation strategies

• Sameeksha Rawat,
• S. M. Tauseef and
• Madhuben Sharma

Beilstein J. Nanotechnol. 2025, 16, 2144–2167, doi:10.3762/bjnano.16.148

• other sensitive aquatic ecosystems. The review describes existing remediation technologies, categorizing these into physical, chemical, and biological interventions, and takes into account emerging sustainable approaches, including biofilm-mediated degradation and nanotechnology-based solutions. The

• pollution; nanotechnology; remediation; Review 1 Introduction The Himalayan lakes, often known as the “Water Towers of Asia,” serve an important role in biodiversity conservation, downstream hydraulic management, and supplying freshwater supplies to millions of people. Sau et al. explain that Pangong

• permanently removed without causing secondary pollution [72]. 5.3.2 Nanotechnology for degradation. Nanotechnology offers a novel method for the accurate and effective breakdown of MPs. Under UV light, nanomaterials such as ZnO and TiO2 work as photocatalysts to break down MPs into CO2 and water, which are

Quality by design optimization of microemulsions for topical delivery of Passiflora setacea seed oil

• Daniel T. Pereira,
• Douglas Dourado,
• Danielle T. Freire,
• Dayanne L. Porto,
• Cícero F. S. Aragão,
• Myla L. de Souza,
• Guilherme R. S. de Araujo,
• Ana Maria Costa,
• Wógenes N. Oliveira,
• Anne Sapin-Minet,
• Éverton N. Alencar and
• Eryvaldo Sócrates T. Egito

Beilstein J. Nanotechnol. 2025, 16, 2116–2131, doi:10.3762/bjnano.16.146

• assays demonstrated high cell viability for ME at concentrations below 2 mg/mL in RAW 264.7 macrophages and 0.5 mg/mL in human umbilical vein endothelial cells. Overall, this work presents a promising nanotechnology-based topical delivery platform for P. setacea seed oil, employing quality by design

• principles to ensure formulation performance, stability, and skin cell compatibility. Keywords: design of experiments (DoE); microemulsions; nanotechnology; natural products; passion fruit; quality by design; skin delivery; Introduction Species of the Passiflora genus are known for their rich composition

• address these challenges, nanotechnology-based delivery systems, particularly microemulsions (MEs), offer a promising solution. Microemulsions are thermodynamically stable, isotropic mixtures typically composed of oil, water, surfactants, and co-surfactants [6]. Their spontaneous formation, high