Influence of laser beam profile on morphology and optical properties of silicon nanoparticles formed by laser ablation in liquid

• Natalie Tarasenka,
• Vladislav Kornev,
• Alena Nevar and
• Nikolai Tarasenko

Beilstein J. Nanotechnol. 2025, 16, 1533–1544, doi:10.3762/bjnano.16.108

• structure of the formed NPs were analyzed by means of ultraviolet–visible (UV–vis) spectroscopy, high-resolution transmission electron microscopy (HRTEM), selected area electron diffraction (SAED), X-ray diffraction (XRD), and Raman and photoluminescence (PL) spectroscopies. Particle size and morphology

• ) operating at an accelerating voltage of 10 kV. For SEM and Raman measurements, the colloidal solution was deposited onto Al foil by drop casting and dried at room temperature. The Raman measurements were performed under 488 nm excitation using a micro-Raman system (“NanoFlex”, Solar LS, Belarus). The UV–vis

• . Optical characterization The optical properties of Si NPs dispersed in ethanol were investigated using Raman and UV–vis spectroscopy. Initially, Si NPs obtained using Bessel, annular, and Gaussian laser beams were characterized by Raman spectroscopy, and their Raman spectra (vibrational modes) were

Dendrimer-modified carbon nanotubes for the removal and recovery of heavy metal ions from water

• Thao Quynh Ngan Tran,
• Huu Trung Nguyen,
• Subodh Kumar and
• Xuan Thang Cao

Beilstein J. Nanotechnol. 2025, 16, 1522–1532, doi:10.3762/bjnano.16.107

• patterns were recorded on a Shimadzu 6100 X-ray diffractometer in a 2θ range of 10–80°, providing insights into the crystalline structure and phase composition of the CNTs before and after modification. UV–vis spectroscopy was used to monitor adsorption of metal ions by the interaction of dendrimerized

Cross-reactivities in conjugation reactions involving iron oxide nanoparticles

• Shoronia N. Cross,
• Katalin V. Korpany,
• Hanine Zakaria and
• Amy Szuchmacher Blum

Beilstein J. Nanotechnol. 2025, 16, 1504–1521, doi:10.3762/bjnano.16.106

• using UV–vis spectroscopy. Following the CuAAC reaction with Cy5-azide, we immediately see a visible change in the color of the IONPs from brown to deep blue-green (Figure 3B, inset). The UV–vis spectrum of the IONP-PPA CuAAC product (Figure 3B.i) shows two broad peaks at ≈610 and 650 nm, which

• -substituted ring structures, thereby providing evidence against the formation of tetra-substituted rings, making quinone reactions unlikely. There is an important difference observed in the lineshapes of the post-CuAAC UV–vis spectra of IONP-PPA, and the EDC/NHS-free control (Figure 2B.i and 2C.i). Most

• bond formation with EDC activation, while no amides were detected in the EDC-free control, as expected. Our UV–vis results suggest a denser dye loading on IONP-PPA than the EDC-free control, which suggests more available binding sites (alkynes) on IONP-PPA. The C 1s XPS spectra also suggest the

Laser processing in liquids: insights into nanocolloid generation and thin film integration for energy, photonic, and sensing applications

• Akshana Parameswaran Sreekala,
• Pooja Raveendran Nair,
• Jithin Kundalam Kadavath,
• Bindu Krishnan,
• David Avellaneda Avellaneda,
• M. R. Anantharaman and
• Sadasivan Shaji

Beilstein J. Nanotechnol. 2025, 16, 1428–1498, doi:10.3762/bjnano.16.104

• pulse excitation (532 nm). The morphological changes induced by thermal and photochemical effects were found to influence the optical properties of these particles. Another commonly reported semiconductor material by LFL is zinc oxide (ZnO) [33][34]. The optical properties, particularly the UV emission

• flake-like aggregated structures with an average particle size of 77 nm were observed [114]. ZnO NPs were prepared by laser ablation of metallic zinc powders suspended in water, and thin films were fabricated by drop casting [115]. Figure 11a represents the UV–vis emission intensity ratio of ZnO

Photochemical synthesis of silver nanoprisms via green LED irradiation and evaluation of SERS activity

• Tuan Anh Mai-Ngoc,
• Nhi Kieu Vo,
• Cong Danh Nguyen,
• Thi Kim Xuan Nguyen and
• Thanh Sinh Do

Beilstein J. Nanotechnol. 2025, 16, 1417–1427, doi:10.3762/bjnano.16.103

• , photochemical methods utilizing physical agents such as lasers [5], UV light [6], or LEDs [7][8][9] have gained attention due to their superior spatial and temporal control, high stability of the resulting AgNPrs and avoidance of environmentally unfriendly reducing agents [8][10]. The strong surface plasmon

• yield. The SERS performance of the synthesized AgNPrs, evaluated using 4-MBA as a probe molecule, demonstrated significantly enhanced Raman signals compared to the initial AgNPs seeds, highlighting their potential applicability in SERS-based sensors. Results and Discussion Synthesis of seeds The UV–vis

• distribution in the Figure 1b,c showed that the seed predominantly contained spherical silver nanoparticles with a size of approximately 10 nm, in agreement with the UV–vis spectrum result. Manufacturing of AgNPrs AgNPrs were synthesized in two steps, that is, (i) synthesis of AgNPs as seeds and (ii

Synthesis and antibacterial properties of nanosilver-modified cellulose triacetate membranes for seawater desalination

• Lei Wang,
• Shizhe Li,
• Kexin Xu,
• Wenjun Li,
• Ying Li and
• Gang Liu

Beilstein J. Nanotechnol. 2025, 16, 1380–1391, doi:10.3762/bjnano.16.100

• ) membrane for water desalination. The TiO2-modified membrane demonstrated significant antibacterial activity against Escherichia coli. Under UV light, the survival ratio of bacterial cells reduced to 5% within 4 h; the membrane was completely sterilized within 5 h. This effect is attributed to the

Ferroptosis induction by engineered liposomes for enhanced tumor therapy

• Alireza Ghasempour,
• Mohammad Amin Tokallou,
• Mohammad Reza Naderi Allaf,
• Mohsen Moradi,
• Hamideh Dehghan,
• Mahsa Sedighi,
• Mohammad-Ali Shahbazi and
• Fahimeh Lavi Arab

Beilstein J. Nanotechnol. 2025, 16, 1325–1349, doi:10.3762/bjnano.16.97

Enhancing the photoelectrochemical performance of BiOI-derived BiVO₄ films by controlled-intensity current electrodeposition

• Huu Phuc Dang,
• Khanh Quang Nguyen,
• Nguyen Thi Mai Tho and
• Tran Le

Beilstein J. Nanotechnol. 2025, 16, 1289–1301, doi:10.3762/bjnano.16.94

• . Characteristics of materials X-ray diffraction (XRD, Bruker D8 Advance) and Raman spectroscopy (LabRAM Odyssey Semiconductor) were used to analyze the crystal structures of photoanodes. UV–vis absorption spectra were obtained using a Cary 60 spectrophotometer. X-ray photoelectron spectroscopy (XPS, VG ESCALAB250

• performance owing to improved charge transport and enhanced surface reaction sites. Optical properties (UV–vis) UV–vis absorption spectroscopy (Figure 3) showed that BiVO4 samples absorb visible light, with absorption edges between 502 and 541 nm and optical bandgaps between 2.46 and 2.30 eV (Figure 3b

• , as well as the reduced electron–hole recombination rates observed in the Raman and UV–vis analyses. The long-term photoelectrochemical stability of the optimized BiVO4(326) photoanode was evaluated using chronoamperometry under continuous AM1.5G illumination at 1.23 V vs RHE in 0.50 M Na2SO4

Functional bio-packaging enhanced with nanocellulose from rice straw and cinnamon essential oil Pickering emulsion for fruit preservation

• Tuyen B. Ly,
• Duong D. T. Nguyen,
• Hieu D. Nguyen,
• Yen T. H. Nguyen,
• Bup T. A. Bui,
• Kien A. Le and
• Phung K. Le

Beilstein J. Nanotechnol. 2025, 16, 1234–1245, doi:10.3762/bjnano.16.91

• exhibits good heat-resistance, mechanical, and water-barrier properties. At an emulsion concentration as low as 10% (v/w) in the casting solution, high UV absorbance capacity (up to 100% UVC), high antibacterial activity (92.4% Escherichia coli inhibition), and good antioxidative properties (up to 43% DPPH

• significantly in the UV region (300–400 nm) (Figure 4b), demonstrating strong UV blocking capability [49]. The transmittance even dropped to near zero in the UVC range (280–315 nm). Above 400 nm, the transmittance was higher but remained below 100%, highlighting the dual function of PE-CEO in absorbing harmful

• UV rays while partially limiting visible light transmission (Figure 4d). This makes rCBP ideal for preserving light-sensitive products such as fruits and vegetables, protecting them from photodegradation and extending their shelf life [24]. This effect can be attributed to the presence of

Hydrogels and nanogels: effectiveness in dermal applications

• Jéssica da Cruz Ludwig,
• Diana Fortkamp Grigoletto,
• Daniele Fernanda Renzi,
• Wolf-Rainer Abraham,
• Daniel de Paula and
• Najeh Maissar Khalil

Beilstein J. Nanotechnol. 2025, 16, 1216–1233, doi:10.3762/bjnano.16.90

• percentage of animals with onset tumors in the group pre-treated with quercetin nanogels (0.12%) + TiO2 (15%) were significantly lower (p < 0.05) compared with the group exposed to UV radiation (control group). Besides, the nanogel containing quercetin (0.12%) + TiO2 (15%) significantly reduced (p < 0.001

• ) the expression of COX-2, EP3, EP4, PCNA, and cyclin D1 in contrast to the group that was pre-treated with quercetin and TiO2 only. Thus, nanogels containing quercetin+TiO2 held promise for the chemoprevention of UV-induced skin photocarcinogenesis. In recent years, the pharmaceutical industry and the

Investigation of the solubility of protoporphyrin IX in aqueous and hydroalcoholic solvent systems

• Michelly de Sá Matsuoka,
• Giovanna Carla Cadini Ruiz,
• Marcos Luciano Bruschi and
• Jéssica Bassi da Silva

Beilstein J. Nanotechnol. 2025, 16, 1209–1215, doi:10.3762/bjnano.16.89

• , the findings observed at 0.4 mg/mL PpIX are not in line. While spectrophotometric readings indicated high solubility, the visual inspection revealed turbidity, suggesting incomplete dissolution of the photosensitizer. This discrepancy may be attributed to the filtration step performed prior to UV–vis

Chitosan nanocomposite containing rotenoids: an alternative bioinsecticidal approach for the management of Aedes aegypti

• Maria A. A. Bertonceli,
• Vitor D. C. Cristo,
• Ivo J. Vieira,
• Francisco J. A. Lemos,
• Arnoldo R. Façanha,
• Raimundo Braz-Filho,
• Gustavo V. T. Batista,
• Luis G. M. Basso,
• Sérgio H. Seabra,
• Thalya S. R. Nogueira,
• Felipe F. Moreira,
• Arícia L. E. M. Assis,
• Antônia E. A. Oliveira and
• Kátia V. S. Fernandes

Beilstein J. Nanotechnol. 2025, 16, 1197–1208, doi:10.3762/bjnano.16.88

• and UV light exposure, as widely documented in the literature [29]. The analysis of third-instar Ae. aegypti larvae exposed to the nanocomposite CS/TPP–β-CD–rot (Figure 6) revealed notable dose-dependent morphological alterations. From 50 ppm onwards, the appearance of abnormal excretion in the anal

Electronic and optical properties of chloropicrin adsorbed ZnS nanotubes: first principle analysis

• Prakash Yadav,
• Boddepalli SanthiBhushan and
• Anurag Srivastava

Beilstein J. Nanotechnol. 2025, 16, 1184–1196, doi:10.3762/bjnano.16.87

• pristine ZnS NT and CP-adsorbed ZnS NT at orientations A, B, C, and D reveal significant variations that elucidate the interaction mechanisms between CP molecules and ZnS NTs. For pristine ZnS NTs, the spectrum displays multiple sharp peaks in the UV region (250–400 nm), with the strongest peak occurring

• at approximately 290–300 nm. This behavior is attributed to the intrinsic wide bandgap of ZnS (≈3.68 eV), which confines its absorption to the UV range, as confirmed by both experimental and theoretical studies on ZnS nanostructures [68]. These peaks arise from interband electronic transitions

• highlighting the suitability of ZnS nanostructures for UV photodetectors, sensors, and photocatalytic applications, where high UV sensitivity is critical [69]. Upon CP molecule adsorption, significant redshifts in the absorption spectra are observed across all orientations, indicative of bandgap narrowing

Piezoelectricity of hexagonal boron nitrides improves bone tissue generation as tested on osteoblasts

• Sevin Adiguzel,
• Nilay Cicek,
• Zehra Cobandede,
• Feray B. Misirlioglu,
• Hulya Yilmaz and
• Mustafa Culha

Beilstein J. Nanotechnol. 2025, 16, 1068–1081, doi:10.3762/bjnano.16.78

• drop-casting 1 μL of hBN suspension (prepared in deionized water) onto a TEM grid. Fourier-transform infrared spectroscopy (FTIR, Shimadzu IRAffinity-1S) and Raman spectroscopy (Renishaw, 532 nm laser) were used to analyze chemical bonds and assess crystallinity. UV–visible spectroscopy (Varian Cary UV

• NMs, 5% silver nitrate solution was added to each well and exposed to UV light for 50 min. Afterward, the cells were washed with diH2O three times, and 5% sodium thiosulfate solution was added to each well to stop the reaction. After 3 min, the cells were rinsed under running tap water for 1 min and

• using a variety of techniques including FTIR, Raman, UV–vis, DLS, and PRFM to confirm their physicochemical properties. Characterization of hexagonal boron nitrides The TEM images of the synthesized hBNs are shown in Supporting Information File 1, Figure S3 (a) and (b). As seen, hBNs have platelet-like

A calix[4]arene-based supramolecular nanoassembly targeting cancer cells and triggering the release of nitric oxide with green light

• Cristina Parisi,
• Loredana Ferreri,
• Tassia J. Martins,
• Francesca Laneri,
• Samantha Sollima,
• Antonina Azzolina,
• Antonella Cusimano,
• Nicola D’Antona,
• Grazia M. L. Consoli and
• Salvatore Sortino

Beilstein J. Nanotechnol. 2025, 16, 1003–1013, doi:10.3762/bjnano.16.75

• , supramolecular nanoconstructs, and nanomaterials photoreleasing NO have been developed as potential nanomedicines over the last decades [40][41][42][43][44][45][46][47][48][49][50]. In this regard, generating NO with highly biocompatible long wavelength green or red light is highly desirable over blue or even UV

• gel (Merck Kieselgel 60, 230–400 mesh ASTM). The progress of the reactions was followed by thin layer chromatography (TLC) on 5 × 20 cm plates with a layer thickness of 0.2 mm. UV–vis spectra were recorded with a Jasco V-560 spectrophotometer using quartz cuvettes with an optical path length of 1 cm

Synthesis of biowaste-derived carbon-dot-mediated silver nanoparticles and the evaluation of electrochemical properties for supercapacitor electrodes

• Navya Kumari Tenkayala,
• Chandan Kumar Maity,
• Md Moniruzzaman and
• Subramani Devaraju

Beilstein J. Nanotechnol. 2025, 16, 933–943, doi:10.3762/bjnano.16.71

• color changing from brown to dark brownish black confirmed the synthesis of PG-CDs-AgNP within 2 h. After 2 h of reaction, the sample was collected for UV–vis studies. The UV–vis spectra were also implemented at 12 and 24 h, respectively. The growth and the formation of PG-CDs-AgNP were recorded by

• using UV–vis spectroscopy. Supporting Information File 1, section S1 contains the details of the material characterization techniques. Results and Discussion Plant extract-mediated production of nanoparticles from noble metal precursors are well reported. In the present work, waste P. pinnata leaf

• evidenced from the progressive color change of the solution as shown by surface plasmon resonance (SPR). Structural and morphological analysis The optical properties of PG-CDs and PG-CDs-AgNPs were studied using UV–visible spectroscopy and photoluminescence (PL) spectroscopy. An absorption peak at 275 nm

Ar⁺ implantation-induced tailoring of RF-sputtered ZnO films: structural, morphological, and optical properties

• Manu Bura,
• Divya Gupta,
• Arun Kumar and
• Sanjeev Aggarwal

Beilstein J. Nanotechnol. 2025, 16, 872–886, doi:10.3762/bjnano.16.66

• studied using field-emission scanning electron microscopy (FESEM) along with energy dispersive X-ray spectroscopy (EDS). Cross-sectional images are also obtained to evaluate the thickness of ZnO film. The optical properties of pristine and implanted ZnO films are investigated using a Shimadzu UV–visible

• –NIR spectrophotometer (UV-3600Plus) employed with Integrating Sphere Assembly (ISR-603) in the wavelength range of 200–800 nm. Results and Discussion Structural analysis Grazing incidence X-ray diffraction The grazing incidence X-ray diffraction (GXRD) patterns of pristine ZnO and argon-implanted ZnO

• in ion fluence, F(R) of the films increases (Figure 10). This points towards the degradation of the crystal quality of ZnO films with disordering of atoms and defects in the films. This causes an increased absorption of UV and visible light. Moreover, additional peaks are observed, centered at around

Insights into the electronic and atomic structures of cerium oxide-based ultrathin films and nanostructures using high-brilliance light sources

• Paola Luches and
• Federico Boscherini

Beilstein J. Nanotechnol. 2025, 16, 860–871, doi:10.3762/bjnano.16.65

• , which have similar properties as the ones induced by direct UV photoexcitation across the bandgap. Conclusions and Perspectives The present review reports the advances brought by the use of high-brilliance photon beams generated by synchrotron radiation and FEL sources in the study of cerium oxide-based

Supramolecular hydration structure of graphene-based hydrogels: density functional theory, green chemistry and interface application

• Hon Nhien Le,
• Duy Khanh Nguyen,
• Minh Triet Dang,
• Huyen Trinh Nguyen,
• Thi Bang Tam Dao,
• Trung Do Nguyen,
• Chi Nhan Ha Thuc and
• Van Hieu Le

Beilstein J. Nanotechnol. 2025, 16, 806–822, doi:10.3762/bjnano.16.61

• instrument (Jasco). Ultraviolet–visible absorption spectroscopy (UV–vis) and light transmittance spectroscopy were recorded using a V-670 spectrophotometer (Jasco). Microscopic texture and imaging were observed by a stereo zoom microscope (Optika SZM). Agar diffusion assays were used for testing

• environment and quickly settled down. Stacked agglomerates of GO-SG-ZH powder at the bottom of the dispersion were observed in the micrograph of Figure 6c, while the micrograph of the dispersion of GO-SG-ZH hydrogel showed the absence of stacked structures. In Figure 6d, UV–vis spectra of aqueous dispersions

• GO-SG-ZH hydrogel. (a) XRD pattern of GO-SG-ZH powder. (b) FTIR spectrum of GO-SG-ZH powder. (c) Aqueous dispersions of GO-SG-ZH powder and hydrogel (concentrations of 50 ppm) and their sedimented particles after 1 day (visualized by the optical microscope). (d) UV–vis spectra of aqueous dispersions

Morphology and properties of pyrite nanoparticles obtained by pulsed laser ablation in liquid and thin films for photodetection

• Akshana Parameswaran Sreekala,
• Bindu Krishnan,
• Rene Fabian Cienfuegos Pelaes,
• David Avellaneda Avellaneda,
• Josué Amílcar Aguilar-Martínez and
• Sadasivan Shaji

Beilstein J. Nanotechnol. 2025, 16, 785–805, doi:10.3762/bjnano.16.60

• its ability to absorb UV wavelengths [32]. This concept was used to fabricate photodetectors (PDs) using pyrite NPs on Si substrate as it inherently has the advantages of exceptional photo-absorption, high mobility, and high absorption coefficient as initially mentioned. Self-powering PDs have a

• nanocolloid in this work. The optical properties of nanocolloids and their thin films were evaluated using UV–visible (UV–vis) spectroscopy. The nanoparticle characterization and surface morphology were studied using transmission electron microscopy (TEM), scanning electron microscopy (SEM), and the

• crystalline structure of the films was characterized by X-ray diffraction (XRD). The UV–vis–NIR photodetection properties of p-n junction-based thin films composed of FeS2 nanoparticles are reported. Additionally, the results of various light-sensing parameters evaluated in these photodetectors are also

Synthesis of a multicomponent cellulose-based adsorbent for tetracycline removal from aquaculture water

• Uyen Bao Tran,
• Ngoc Thanh Vo-Tran,
• Khai The Truong,
• Dat Anh Nguyen,
• Quang Nhat Tran,
• Huu-Quang Nguyen,
• Jaebeom Lee and
• Hai Son Truong-Lam

Beilstein J. Nanotechnol. 2025, 16, 728–739, doi:10.3762/bjnano.16.56

• hurdles. Photochemical processes have also garnered significant research interest for tetracycline antibiotic removal, leveraging UV radiation [8][9]. While this approach offers cost-effectiveness, simplicity, and environmental benefits, its efficacy is strongly influenced by the compound’s adsorption

Efficiency of single-pulse laser fragmentation of organic nutraceutical dispersions in a circular jet flow-through reactor

• Tina Friedenauer,
• Maximilian Spellauge,
• Alexander Sommereyns,
• Verena Labenski,
• Tuba Esatbeyoglu,
• Christoph Rehbock,
• Heinz P. Huber and
• Stephan Barcikowski

Beilstein J. Nanotechnol. 2025, 16, 711–727, doi:10.3762/bjnano.16.55

• yield of submicrometer particles and nanoparticles was quantified using UV–vis extinction spectroscopy, scanning electron microscopy, and analytical centrifugation, while high-performance liquid chromatography determined degradation. We found improved fragmentation efficiency at lower mass

• iron phthalocyanines (FePc), but also some purely organic dyes such as naphthalocyanides [25], perylenes [26], perylene diimides [27][28], fullerenes [29][30], and quinacridones [2][31] have been successfully downsized to the nanoscale using nanosecond- and femtosecond-LFL with wavelengths in the UV

• , green, and IR ranges. Metal complex dyes are characterized by high thermal and UV stability and were therefore preferred for initial LFL studies [32]. Asahi et al. and Tamaki et al. repeatedly showed that using a UV nanosecond laser with a repetition rate of several hertz not only produces NPs of

The impact of tris(pentafluorophenyl)borane hole transport layer doping on interfacial charge extraction and recombination

• Konstantinos Bidinakis and
• Stefan A. L. Weber

Beilstein J. Nanotechnol. 2025, 16, 678–689, doi:10.3762/bjnano.16.52

• deposited a mesoporous TiO2 layer from a (transparent) titania paste solution (Aldrich, 16.67 wt % in ethanol) via spin coating and annealed it (same parameters as in the previous step). After each of these titania deposition steps, we subjected the films to a UV-ozone cleaning step (FHR UVO 150) for 30 min

Colloidal few layered graphene–tannic acid preserves the biocompatibility of periodontal ligament cells

• Teissir Ben Ammar,
• Naji Kharouf,
• Dominique Vautier,
• Housseinou Ba,
• Nivedita Sudheer,
• Philippe Lavalle and
• Vincent Ball

Beilstein J. Nanotechnol. 2025, 16, 664–677, doi:10.3762/bjnano.16.51

• of graphene confers antioxidant properties The arrangement of TA molecules on graphene layers and their antioxidant effects were analyzed through three experimental methods. The concentration of TA in the FLG suspension was measured using UV–vis spectroscopy, surface composition changes from graphite

• to unexfoliated graphite (Table S1, Supporting Information File 1), a strong evidence for the incorporation of TA. After exfoliation, the UV spectra analysis indicated that nearly all of TA used in the preparation adhered to the FLG, with only 15 µg remaining as free TA molecules (from an initial

• oxidative stress, thus elucidating the ROS inhibition by FLG–TA. The UV–vis spectroscopic analysis (Figure S5, Supporting Information File 1) revealed a significant decrease in absorbance of the FLG–TA composite following exposure to DPPH solution, indicating oxidative modification of the material under ROS

Aprepitant-loaded solid lipid nanoparticles: a novel approach to enhance oral bioavailability

• Mazhar Hussain,
• Muhammad Farooq,
• Muhammad Asad Saeed,
• Muhammad Ijaz,
• Sherjeel Adnan,
• Zeeshan Masood,
• Muhammad Waqas,
• Wafa Ishaq and
• Nabeela Ameer

Beilstein J. Nanotechnol. 2025, 16, 652–663, doi:10.3762/bjnano.16.50

• solutions were collected through micropipette and filtered by using membrane filter (0.45 µm). The APT concentration was determined in the supernatant using a UV–vis spectrophotometer (UV 1800 Shimadzu, Japan) measuring the absorbance at λmax of 210 nm [13]. Drug content and encapsulation efficiency Drug

• (equivalent to 2 mg APT) were placed in a dialysis bag sealed at both ends in dissolution medium. After specified time intervals, samples (5 mL) were taken, replaced with fresh medium and analyzed through UV spectrophotometry at λmax = 210 nm after proper dilution. The drug release kinetics were determined by