Using gold nanoparticles to detect single-nucleotide polymorphisms: toward liquid biopsy

• María Sanromán Iglesias and
• Marek Grzelczak

Beilstein J. Nanotechnol. 2020, 11, 263–284, doi:10.3762/bjnano.11.20

• ]. Several limitations need to be addressed as well. One of the known issues in colloidal biosensing is the spontaneous formation of a protein corona on the surface of the particles in physiological media [146], inhibiting the interaction of the biomarkers with the colloid, thereby altering the sensitivity

The different ways to chitosan/hyaluronic acid nanoparticles: templated vs direct complexation. Influence of particle preparation on morphology, cell uptake and silencing efficiency

• Arianna Gennari,
• Julio M. Rios de la Rosa,
• Erwin Hohn,
• Maria Pelliccia,
• Enrique Lallana,
• Roberto Donno,
• Annalisa Tirella and
• Nicola Tirelli

Beilstein J. Nanotechnol. 2019, 10, 2594–2608, doi:10.3762/bjnano.10.250

• . DLS data were analysed using the Zetasizer Nano software (Malvern). The data were also used to calculate: ρ = Rg/Rh (shape factor). This parameter defines key geometrical characteristics of a colloid. ρ values are given in literature [23] for a variety of particle morphologies. For example, ρ = 0.775

• provides also information about the colloid compactness through parameters such as their average radius of gyration Rg (it depends on the mass distribution), the shape factor ρ defined as the Rg/RH ratio, and the mass fractal dimension Dm defined as the exponent in the relation between mass of a colloidal

• the scaling between the mass of a colloid and its dimension, therefore is a direct measure of its compactness; for example, for a “dense solid” colloid, its value will approach 3, while its values decrease for aggregates, and therefore this parameter has been used for aggregation studies of, e.g

Polyvinylpyrrolidone as additive for perovskite solar cells with water and isopropanol as solvents

• Chen Du,
• Shuo Wang,
• Xu Miao,
• Wenhai Sun,
• Yu Zhu,
• Chengyan Wang and
• Ruixin Ma

Beilstein J. Nanotechnol. 2019, 10, 2374–2382, doi:10.3762/bjnano.10.228

• solar cells, and the preparation method is relatively simple. Overall, it is a low-cost, low-toxicity preparation method to commercialize perovskite solar cells. Experimental Materials Lead nitrate, polyvinylpyrrolidone, chlorobenzene and isopropanol were purchased from Aladdin. SnO2 colloid was

The role of Ag⁺, Ca²⁺, Pb²⁺ and Al³⁺ adions in the SERS turn-on effect of anionic analytes

• Stefania D. Iancu,
• Andrei Stefancu,
• Vlad Moisoiu,
• Loredana F. Leopold and
• Nicolae Leopold

Beilstein J. Nanotechnol. 2019, 10, 2338–2345, doi:10.3762/bjnano.10.224

• solution. The Raman enhancement is not a result of the colloid aggregation since no broadening of the SPR band was observed in the colloid extinction spectra after the SERS activation of the cit-AgNPs/organic acid mixtures with cations. A weak damping of the SPR band is observed only after the addition of

• -AgNP solution, but not at basic pH values. In this study, this pH limitation is overcome. By activating the colloid with 50 µM Al3+ the SERS spectra of salicylic acid could be obtained in the pH 6–9 range, as shown in Supporting Information File 1, Figure S4. In the case of fumaric acid, the

• boil for another 30 min. A pH 6 was measured after the colloid synthesis. SERS measurements. For the SERS measurements, the cit-AgNPs were activated with Ca2+, Pb2+ or Al3+ cations at a final concentration of 50 µM, which were added to the colloidal solution in the form of nitrate or sulfate salts: Ca

Microfluidics as tool to prepare size-tunable PLGA nanoparticles with high curcumin encapsulation for efficient mucus penetration

• Nashrawan Lababidi,
• Valentin Sigal,
• Aljoscha Koenneke,
• Konrad Schwarzkopf,
• Andreas Manz and
• Marc Schneider

Beilstein J. Nanotechnol. 2019, 10, 2280–2293, doi:10.3762/bjnano.10.220

• nanoprecipitation in order to have better control over the kinetics of the colloid formation. To the best of our knowledge, no comprehensive study has presented relevant experimental evidence enabling more insight into the nanoprecipitation mechanism. Our microfluidic system has a unique feature allowing us to

Mannosylated brush copolymers based on poly(ethylene glycol) and poly(ε-caprolactone) as multivalent lectin-binding nanomaterials

• Stefania Ordanini,
• Wanda Celentano,
• Anna Bernardi and
• Francesco Cellesi

Beilstein J. Nanotechnol. 2019, 10, 2192–2206, doi:10.3762/bjnano.10.212

• multivalent fashion, leading to an increase of turbidity. Interestingly, turbidity was not observed with the monovalent compound PEG9-PCL1-Man1, suggesting that the polymer and the resulting nanosized colloid in water do not have a suitable valency for the formation of Con A clusters. We assumed that the

Pulsed laser synthesis of highly active Ag–Rh and Ag–Pt antenna–reactor-type plasmonic catalysts

• Kenneth A. Kane and
• Massimo F. Bertino

Beilstein J. Nanotechnol. 2019, 10, 1958–1963, doi:10.3762/bjnano.10.192

• [1]. Plasmonic coupling results in an increase in the magnitude of the LSPR-induced electric fields. The selective adsorption of NP groupings to the Ag nanostructure concavities may be a result of LSPR-induced electric fields, which are largest in these highly angular regions. The mixed Ag–Pt colloid

• , comprising Ag–Pt heterostructures, was found to exhibit a slight blue-shift of the LSPR, while the mixed Ag–Rh colloid showed a more pronounced red-shift. Pt and Ag are known to possess lower catalytic activity in the reduction of 4-nitrophenol than Rh [21][22]. Accordingly, Pt and Ag exhibited a lower

Nanoarchitectonics meets cell surface engineering: shape recognition of human cells by halloysite-doped silica cell imprints

• Elvira Rozhina,
• Ilnur Ishmukhametov,
• Svetlana Batasheva,
• Farida Akhatova and
• Rawil Fakhrullin

Beilstein J. Nanotechnol. 2019, 10, 1818–1825, doi:10.3762/bjnano.10.176

• cells templates offer other fascinating opportunities due to their cell-mimicking geometries, for example, a novel class of bioinspired colloid particles was fabricated recently. Colloid antibodies were produced via the formation of solid silica shells doped with gold nanoparticles on bacterial cells

• , only HeLa cells were recognised by the imprints, while yeast cells were ignored. Although this does not guarantee an equally effective recognition of other mammalian cells (i.e., in a mixture with HeLa cells), our results open new avenues for the fabrication of colloid particles capable of shape-based

Chiral nanostructures self-assembled from nitrocinnamic amide amphiphiles: substituent and solvent effects

• Hejin Jiang,
• Huahua Fan,
• Yuqian Jiang,
• Li Zhang and
• Minghua Liu

Beilstein J. Nanotechnol. 2019, 10, 1608–1617, doi:10.3762/bjnano.10.156

• Hejin Jiang Huahua Fan Yuqian Jiang Li Zhang Minghua Liu Beijing National Laboratory for Molecular Science (BNLMS), CAS Laboratory of Colloid, Interface and Chemical Thermodynamics, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China University of Chinese Academy of Sciences

BiOCl/TiO₂/diatomite composites with enhanced visible-light photocatalytic activity for the degradation of rhodamine B

• Minlin Ao,
• Kun Liu,
• Xuekun Tang,
• Zishun Li,
• Qian Peng and
• Jing Huang

Beilstein J. Nanotechnol. 2019, 10, 1412–1422, doi:10.3762/bjnano.10.139

• solution A. Solution B was obtained by mixing 4 g of diatomite, 20 mL of ethanol, 0.5 mL of glacial acetic acid and 1.5 mL of 0.1 mol/L nitric acid under stirring. In order to obtain the precursor colloid, solution B was dripped into solution A under stirring. After that, the precursor was dried at 60 °C

Gas sensing properties of individual SnO₂ nanowires and SnO₂ sol–gel nanocomposites

• Alexey V. Shaposhnik,
• Dmitry A. Shaposhnik,
• Sergey Yu. Turishchev,
• Olga A. Chuvenkova,
• Stanislav V. Ryabtsev,
• Alexey A. Vasiliev,
• Xavier Vilanova,
• Francisco Hernandez-Ramirez and
• Joan R. Morante

Beilstein J. Nanotechnol. 2019, 10, 1380–1390, doi:10.3762/bjnano.10.136

• glacial acetic acid. A surplus of hydrogen peroxide was added to the solution: where NH3·H2O was added dropwise to cause hydrolytic precipitation of tin oxide as follows: The obtained colloid was precipitated by centrifugation, dried and annealed. Tin dioxide nanopowder was formed as a result of tin acid

A biomimetic nanofluidic diode based on surface-modified polymeric carbon nitride nanotubes

• Kai Xiao,
• Baris Kumru,
• Lu Chen,
• Lei Jiang,
• Bernhard V. K. J. Schmidt and
• Markus Antonietti

Beilstein J. Nanotechnol. 2019, 10, 1316–1323, doi:10.3762/bjnano.10.130

• Kai Xiao Baris Kumru Lu Chen Lei Jiang Bernhard V. K. J. Schmidt Markus Antonietti Max Planck Institute of Colloids and Interfaces, Department of Colloid Chemistry, 14476 Potsdam, Germany Key Laboratory of Bio-inspired Smart Interfacial Science and Technology of Ministry of Education, School of

Quantitative analysis of annealing-induced instabilities of photo-leakage current and negative-bias-illumination-stress in a-InGaZnO thin-film transistors

• Dapeng Wang and
• Mamoru Furuta

Beilstein J. Nanotechnol. 2019, 10, 1125–1130, doi:10.3762/bjnano.10.112

• Dapeng Wang Mamoru Furuta Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education; Shaanxi Key Laboratory for AdvancedEnergy Devices; Shaanxi Engineering Lab for Advanced Energy Technology, School of Materials Science and Engineering, Shaanxi Normal University, Xi’an 710119

Scavenging of reactive oxygen species by phenolic compound-modified maghemite nanoparticles

• Małgorzata Świętek,
• Yi-Chin Lu,
• Rafał Konefał,
• Liliana P. Ferreira,
• M. Margarida Cruz,
• Yunn-Hwa Ma and
• Daniel Horák

Beilstein J. Nanotechnol. 2019, 10, 1073–1088, doi:10.3762/bjnano.10.108

• . The superparamagnetism of the γ-Fe2O3 colloid was confirmed by SQUID magnetometry through the absence of remanence and coercivity in the magnetic hysteresis curve (Figure 3c,d). The saturation magnetization of the γ-Fe2O3 colloid (4.4 mg/mL was 0.307 A·m2·kg−1 at 260 K. The critical parameter for the

• magnetization of the γ-Fe2O3@Hep colloid (by 2%) at 260 K was observed compared to the saturation magnetization of γ-Fe2O3 at the same particle concentration (inset in Figure 3c). This decrease was caused by the increased content of the nonmagnetic fraction in the particles. The TGA result of the γ-Fe2O3@Hep

• compared to that of the γ-Fe2O3 colloid. As expected, the magnetic saturation decreased with increasing content of the nonmagnetic organic phase at the nanoparticle surface, which was previously verified for the γ-Fe2O3@Hep colloid. At the same concentration, the saturation magnetization values of the

Mechanism of silica–lysozyme composite formation unravelled by in situ fast SAXS

• Tomasz M. Stawski,
• Daniela B. van den Heuvel,
• Rogier Besselink,
• Dominique J. Tobler and
• Liane G. Benning

Beilstein J. Nanotechnol. 2019, 10, 182–197, doi:10.3762/bjnano.10.17

• inorganic nanoparticles (NPs) and proteins in aqueous media is of paramount interest for colloid chemistry. In particular, the interactions between silica (SiO2) NPs and lysozyme (LZM) have attracted attention, because LZM is well-known to adsorb strongly to silica NPs, while at the same time preserving its

• : composite; lysozyme; scattering; silica; small-angle X-ray scattering (SAXS); Introduction A mechanistic understanding of aggregation in aqueous media leading to the formation of composites of inorganic nanoparticles and proteins is of paramount interest for colloid chemistry, Earth sciences, or the design

Pull-off and friction forces of micropatterned elastomers on soft substrates: the effects of pattern length scale and stiffness

• Peter van Assenbergh,
• Marike Fokker,
• Julian Langowski,
• Jan van Esch,
• Marleen Kamperman and
• Dimitra Dodou

Beilstein J. Nanotechnol. 2019, 10, 79–94, doi:10.3762/bjnano.10.8

Hybrid Au@alendronate nanoparticles as dual chemo-photothermal agent for combined cancer treatment

• Anouchka Plan Sangnier,
• Romain Aufaure,
• Laurence Motte,
• Claire Wilhelm,
• Erwann Guenin and
• Yoann Lalatonne

Beilstein J. Nanotechnol. 2018, 9, 2947–2952, doi:10.3762/bjnano.9.273

• negative zeta potential, equal to −37.5 ± 9.1 mV confirms the presence of alendronate on the surface providing negative charges, which allow colloid stabilization despite the presence of ammonium cations. Au@alendronate NPs as NIR photothermal nano-heater Since gold NPs bring their own therapeutic asset

Enhancement of X-ray emission from nanocolloidal gold suspensions under double-pulse excitation

• Wei-Hung Hsu,
• Frances Camille P. Masim,
• Armandas Balčytis,
• Hsin-Hui Huang,
• Tetsu Yonezawa,
• Aleksandr A. Kuchmizhak,
• Saulius Juodkazis and
• Koji Hatanaka

Beilstein J. Nanotechnol. 2018, 9, 2609–2617, doi:10.3762/bjnano.9.242

• in time and space. Results and Discussion Two-pulse excitation for X-ray emission Figure 2 shows the X-ray generation as a function of the time between the pre-pulse of 80 μJ and the main pulse of 700 μJ. Strong X-ray generation was observed at a delay of 1 ns in the case of the gold colloid. For the

Exploring the photoleakage current and photoinduced negative bias instability in amorphous InGaZnO thin-film transistors with various active layer thicknesses

• Dapeng Wang and
• Mamoru Furuta

Beilstein J. Nanotechnol. 2018, 9, 2573–2580, doi:10.3762/bjnano.9.239

• Dapeng Wang Mamoru Furuta Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education; Shaanxi Key Laboratory for Advanced Energy Devices; Shaanxi Engineering Lab for Advanced Energy Technology, School of Materials Science and Engineering, Shaanxi Normal University, Xi’an 710119

Cytotoxicity of doxorubicin-conjugated poly[N-(2-hydroxypropyl)methacrylamide]-modified γ-Fe₂O₃ nanoparticles towards human tumor cells

• Zdeněk Plichta,
• Yulia Kozak,
• Rostyslav Panchuk,
• Viktoria Sokolova,
• Matthias Epple,
• Lesya Kobylinska,
• Pavla Jendelová and
• Daniel Horák

Beilstein J. Nanotechnol. 2018, 9, 2533–2545, doi:10.3762/bjnano.9.236

• Ar atmosphere and the polymerization proceeded at 60 °C for 16 h. The resulting PHPMA was washed with ethyl acetate and separated by filtration yielding 1.92 g of the polymer (Mn = 177 kDa). Aqueous solution of PHPMA (2 mL; 0.1 g PHPMA/mL) was then added to the γ-Fe2O3 colloid (2 mL; 0.1 g of γ-Fe2O3

• /mL) to obtain γ-Fe2O3@PHPMA. Second, P(HPMA-MMAA)-Dox (0.1–13.0 µg) was dissolved in aqueous γ-Fe2O3@PHPMA colloid (2–260 µg; 50 mg γ-Fe2O3/mL) to get γ-Fe2O3@P(HPMA-MMAA)-Dox before use in the cell experiments. Characterization methods 1H NMR (in CDCl3) and FTIR spectra of MMAA were recorded on a

• , clustering of the γ-Fe2O3@PHPMA particles also contributes to increased values of Dh. The ζ-potential of γ-Fe2O3@PHPMA substantially differed from that of γ-Fe2O3, reaching +38 mV and indicating the presence of coating. After mixing γ-Fe2O3@PHPMA nanoparticle colloid with P(HPMA-MMAA)-Dox, its chains readily

Enhanced antineoplastic/therapeutic efficacy using 5-fluorouracil-loaded calcium phosphate nanoparticles

• Shanid Mohiyuddin,
• Saba Naqvi and
• Gopinath Packirisamy

Beilstein J. Nanotechnol. 2018, 9, 2499–2515, doi:10.3762/bjnano.9.233

• colloid (data not shown). Fourier-transform infrared spectroscopy analysis The vibrational spectrum in the infrared region of synthesized CaP@5-FU NPs and CaP NPs with the drug 5-FU was observed to establish the chemical confirmation of the synthesized material with respect to the functional group. The

Droplet-based synthesis of homogeneous magnetic iron oxide nanoparticles

• Christian D. Ahrberg,
• Ji Wook Choi and
• Bong Geun Chung

Beilstein J. Nanotechnol. 2018, 9, 2413–2420, doi:10.3762/bjnano.9.226

• potential of 20.2 ± 0.25 mV, and particles synthesized in droplets had a zeta potential of 16.9 ± 0.5 mV. The two measured potentials are in the same range, indicating a relative colloid stability of the particle solutions [33]. To test the advantages of droplet synthesis over batch synthesis, particle size

SERS active Ag–SiO₂ nanoparticles obtained by laser ablation of silver in colloidal silica

• Cristina Gellini,
• Francesco Muniz-Miranda,
• Alfonso Pedone and
• Maurizio Muniz-Miranda

Beilstein J. Nanotechnol. 2018, 9, 2396–2404, doi:10.3762/bjnano.9.224

• irradiation time of the silver target was about 10 min. TEM samples were obtained by dropping a small amount of colloid onto carbon-coated copper grids and allowing it to evaporate. The images were recorded with a Philips CM12 at 120 kV. UV–visible absorption spectra of the colloidal suspensions were obtained

• scheme reported in Figure S1 of Supporting Information File 1. This procedure results in the emergence of the plasmonic band of nanometer-sized silver, observed in the absorption spectrum at 399 nm (Figure 1). The shift of the maximum from 395 nm, as observed in Ag colloid obtained by ns-pulsed laser

• used in the past (10 wt % SiO2) to obtain silica doped with silver [35]. This concentration is optimal for our purposes, that is, having a colloid with a high concentration of silica to exploit its adsorbent capacities, and limiting the background signal of silica. However, we have studied, during the

The role of adatoms in chloride-activated colloidal silver nanoparticles for surface-enhanced Raman scattering enhancement

• Nicolae Leopold,
• Andrei Stefancu,
• Krisztian Herman,
• István Sz. Tódor,
• Stefania D. Iancu,
• Vlad Moisoiu and
• Loredana F. Leopold

Beilstein J. Nanotechnol. 2018, 9, 2236–2247, doi:10.3762/bjnano.9.208

• colloid obtained by Ag+ reduction with citrate (cit-AgNPs), proposed by Lee and Meisel in 1982 [1]. Although the preparation of cit-AgNPs requires boiling conditions, this colloid is often preferred due to its high preparation success rate. Another often used SERS substrate is the silver colloid obtained

• of the colloid and therefore the aggregation of nanoparticles. Consequently, according to literature, electromagnetic hot spots, i.e., sites of highly increased field strength, are generated in the gaps between adjacent nanoparticles [10][11]. The maximal values for electromagnetic enhancement are on

• picture of the experimental setup used for the synthesis of Cl-AgNPs (Figure 1A) and a picture of the resulting colloid (Figure 1B). After the first 3 min of light exposure, the solution turned pale yellow; after 5 min of light exposure, an intense gray-brown color indicated a high concentration of AgNPs

Electrospun one-dimensional nanostructures: a new horizon for gas sensing materials

• Muhammad Imran,
• Nunzio Motta and
• Mahnaz Shafiei

Beilstein J. Nanotechnol. 2018, 9, 2128–2170, doi:10.3762/bjnano.9.202