Self-organization of gold nanoparticles on silanated surfaces

• Htet H. Kyaw,
• Salim H. Al-Harthi,
• Azzouz Sellai and
• Joydeep Dutta

Beilstein J. Nanotechnol. 2015, 6, 2345–2353, doi:10.3762/bjnano.6.242

• structures [8]. AuNPs have been studied intensively for a wide range of applications such as catalysis [9], biosensing [10], colorimetric sensing [11], optical sensing (surface plasmon resonance (SPR) and surface-enhanced Raman scattering (SERS)) [12][13], photonics [13][14], photovoltaic devices [15] and

Optimized design of a nanostructured SPCE-based multipurpose biosensing platform formed by ferrocene-tethered electrochemically-deposited cauliflower-shaped gold nanoparticles

• Wicem Argoubi,
• Maroua Saadaoui,
• Sami Ben Aoun and
• Noureddine Raouafi

Beilstein J. Nanotechnol. 2015, 6, 1840–1852, doi:10.3762/bjnano.6.187

• ferrocene groups after the addition of antigen. One can conclude that ferrocene is useful as a transducing system to follow biosensing events but foreseeing the exact electrochemical behavior (amperometric vs potentiometric) remains very difficult. Furthermore, the redox center directly linked to the gold

• the specific analyte the current variation is weak denoting a very good specificity of the device. The current rise in the latter case is probably due to structural similarity between gIgG (i.e., antibody to hIgG antigen produced in goat) and the other immune proteins. Enzyme-based biosensing The

• fast electron-transfer rates from the redox moiety to the electrode surface. Furthermore, the ferrocene vicinity to the HRP enzyme is useful to constantly re-oxidize the enzyme FAD cofactor thus allowing the design of fast response biosensing devices endowed with a large dynamic range. The LoD and the

Template-controlled mineralization: Determining film granularity and structure by surface functionality patterns

• Nina J. Blumenstein,
• Jonathan Berson,
• Stefan Walheim,
• Petia Atanasova,
• Johannes Baier,
• Joachim Bill and
• Thomas Schimmel

Beilstein J. Nanotechnol. 2015, 6, 1763–1768, doi:10.3762/bjnano.6.180

• the site-selective mineralization of a semiconductor material, zinc oxide (ZnO), on a chemically patterned surface [3]. ZnO thin films are of special interest since they can be used for different applications such as solar cells [16], biosensing devices [17] and others [18]. By using a nearly

Thermal treatment of magnetite nanoparticles

• Beata Kalska-Szostko,
• Urszula Wykowska,
• Dariusz Satula and
• Per Nordblad

Beilstein J. Nanotechnol. 2015, 6, 1385–1396, doi:10.3762/bjnano.6.143

• their application in various fields. The list of possible applications encompasses biomedical engineering, MRI contrast agents, hyperthermia treatment, sensing and biosensing [2][3]. They are also very promising candidates for electrical-related applications, for example, energy and magnetic storage

Growth and morphological analysis of segmented AuAg alloy nanowires created by pulsed electrodeposition in ion-track etched membranes

• Ina Schubert,
• Loic Burr,
• Christina Trautmann and
• Maria Eugenia Toimil-Molares

Beilstein J. Nanotechnol. 2015, 6, 1272–1280, doi:10.3762/bjnano.6.131

• for surface enhanced Raman spectroscopy [38][41][42][43] and for biosensing [44]. Furthermore, such gaps with precisely controlled dimensions allow for the systematic investigation of multipole surface plasmon modes [39][45][46]. Because of their high electrical conductivity [47], Au and Ag metallic

Synergic combination of the sol–gel method with dip coating for plasmonic devices

• Cristiana Figus,
• Maddalena Patrini,
• Francesco Floris,
• Lucia Fornasari,
• Paola Pellacani,
• Gerardo Marchesini,
• Andrea Valsesia,
• Flavia Artizzu,
• Daniela Marongiu,
• Michele Saba,
• Franco Marabelli,
• Andrea Mura,
• Giovanni Bongiovanni and
• Francesco Quochi

Beilstein J. Nanotechnol. 2015, 6, 500–507, doi:10.3762/bjnano.6.52

• 10.3762/bjnano.6.52 Abstract Biosensing technologies based on plasmonic nanostructures have recently attracted significant attention due to their small dimensions, low-cost and high sensitivity but are often limited in terms of affinity, selectivity and stability. Consequently, several methods have been

• at a metal–dielectric interface [1][2][3][4][5]. Recently, due to such remarkable properties, biosensing technologies based on plasmonic nanostructures have attracted significant attention, particularly in the development of label-free sensors [6][7][8]. It is well known that surface plasmons (SPs

• hydrophobic property of the surface is an important characteristic from the perspective of biosensing applications since it also allows for altering the surface affinity for specific molecules. The surface of the films prepared from fresh sol of pH ≈4 was further characterized through contact angle

Hollow plasmonic antennas for broadband SERS spectroscopy

• Gabriele C. Messina,
• Mario Malerba,
• Pierfrancesco Zilio,
• Ermanno Miele,
• Michele Dipalo,
• Lorenzo Ferrara and
• Francesco De Angelis

Beilstein J. Nanotechnol. 2015, 6, 492–498, doi:10.3762/bjnano.6.50

• large enhancement of the vibrational features both in the case of resonant excitation and out-of-resonance excitation. Such characteristics indicate that these structures are potential candidates for plasmonic enhancers in multifunctional opto-electronic biosensors. Keywords: biosensing; multiband

• has become an important factor for the routine application of this technique to biology. There has been a significant increase in the number of studies concerning applications based on plasmonic effects in recent years. The areas of interest range from biomedicine, with examples of biosensing devices

A scanning probe microscope for magnetoresistive cantilevers utilizing a nested scanner design for large-area scans

• Tobias Meier,
• Alexander Förste,
• Ali Tavassolizadeh,
• Karsten Rott,
• Dirk Meyners,
• Roland Gröger,
• Günter Reiss,
• Eckhard Quandt,
• Thomas Schimmel and
• Hendrik Hölscher

Beilstein J. Nanotechnol. 2015, 6, 451–461, doi:10.3762/bjnano.6.46

• effects; magnetostriction; scanning probe microscopes and components; Introduction Since its invention in the 1980s [1] the atomic force microscope (AFM) became a versatile tool frequently used in nanoscale metrology, biosensing, maskless lithography and high density data storage with nearly as many

Functionalization of α-synuclein fibrils

• Simona Povilonienė,
• Vida Časaitė,
• Virginijus Bukauskas,
• Arūnas Šetkus,
• Juozas Staniulis and
• Rolandas Meškys

Beilstein J. Nanotechnol. 2015, 6, 124–133, doi:10.3762/bjnano.6.12

• ][45][54] and the construction of biosensing platforms [22]. Herein we present a feasible method to perform the postassembly bio-functionalization of amyloid fibrils. Our results demonstrate the robustness and stability of such amyloid. The resultant multicomponent nanostructure (nanoladders) should

Formation of stable Si–O–C submonolayers on hydrogen-terminated silicon(111) under low-temperature conditions

• Yit Lung Khung,
• Siti Hawa Ngalim,
• Andrea Scaccabarozzi and
• Dario Narducci

Beilstein J. Nanotechnol. 2015, 6, 19–26, doi:10.3762/bjnano.6.3

• order to gain access to the electronic properties of silicon, it is imperative that the organic layer on the top surface be kept thin enough to avoid a masking of the intrinsic properties of silicon, especially in biosensing application [1]. So far, hydrosilylation is among the most commonly accepted

Sequence-dependent electrical response of ssDNA-decorated carbon nanotube, field-effect transistors to dopamine

• Hari Krishna Salila Vijayalal Mohan,
• Jianing An and
• Lianxi Zheng

Beilstein J. Nanotechnol. 2014, 5, 2113–2121, doi:10.3762/bjnano.5.220

• electronic platform for biosensing [14]. Previously, numerous works have demonstrated that nucleic acid-functionalized CNT-based FETs exhibit fast, specific, and reproducible response to the detection of various polar molecules [15][16]. Since ssDNA has four bases, it gives the possibility of numerous

Effect of channel length on the electrical response of carbon nanotube field-effect transistors to deoxyribonucleic acid hybridization

• Hari Krishna Salila Vijayalal Mohan,
• Jianing An,
• Yani Zhang,
• Chee How Wong and
• Lianxi Zheng

Beilstein J. Nanotechnol. 2014, 5, 2081–2091, doi:10.3762/bjnano.5.217

• -dimensional electronic materials, and their further development has been encouraged in high frequency applications [8][9], chemical sensing [10][11] and biosensing [12][13]. Recently, SWCNTs have been demonstrated as one of the best biosensors for a number of reasons: i) their diameter (several nanometers) is

• characteristics, which are indicators of the various contributing FET biosensing mechanisms [19], vary with channel length. A change in more than one of these electrical parameters after hybridization indicates the influence of multiple FET mechanisms. Therefore, it becomes essential to take into consideration

High speed e-beam lithography for gold nanoarray fabrication and use in nanotechnology

• Jorge Trasobares,
• François Vaurette,
• Marc François,
• Hans Romijn,
• Jean-Louis Codron,
• Dominique Vuillaume,
• Didier Théron and
• Nicolas Clément

Beilstein J. Nanotechnol. 2014, 5, 1918–1925, doi:10.3762/bjnano.5.202

• after the self-assembly process. The developed technology, which will surely be of great importance for molecular electronics study on such nanoarrays, also promising exciting future works in chemistry and biosensing. Experimental Nanoarray fabrication As described in [1][8], for e-beam lithography, we

Mechanical properties of sol–gel derived SiO₂ nanotubes

• Boris Polyakov,
• Mikk Antsov,
• Sergei Vlassov,
• Leonid M Dorogin,
• Mikk Vahtrus,
• Roberts Zabels,
• Sven Lange and
• Rünno Lõhmus

Beilstein J. Nanotechnol. 2014, 5, 1808–1814, doi:10.3762/bjnano.5.191

• environmentally sensitive materials [4][5], biological and biosensing applications [6][7][8], waveguide optics and photonics [9][10][11][12]. However, only a few publications were dedicated to the investigation of the mechanical properties of one-dimensional silica nanostructures, and even less to the ones

Different endocytotic uptake mechanisms for nanoparticles in epithelial cells and macrophages

• Dagmar A. Kuhn,
• Dimitri Vanhecke,
• Benjamin Michen,
• Fabian Blank,
• Peter Gehr,
• Alke Petri-Fink and
• Barbara Rothen-Rutishauser

Beilstein J. Nanotechnol. 2014, 5, 1625–1636, doi:10.3762/bjnano.5.174

• delivery [1][2][3][4][5][6], biosensing [7] and bio-medical imaging [8]. In order to develop optimal NPs for biomedical use, much attention is given to the understanding of the basic mechanism of NP interactions with cellular systems at the single cellular level [9][10][11]. It has already been shown that

In vitro interaction of colloidal nanoparticles with mammalian cells: What have we learned thus far?

• Moritz Nazarenus,
• Qian Zhang,
• Mahmoud G. Soliman,
• Pablo del Pino,
• Beatriz Pelaz,
• Susana Carregal-Romero,
• Joanna Rejman,
• Barbara Rothen-Rutishauser,
• Martin J. D. Clift,
• Reinhard Zellner,
• G. Ulrich Nienhaus,
• James B. Delehanty,
• Igor L. Medintz and
• Wolfgang J. Parak

Beilstein J. Nanotechnol. 2014, 5, 1477–1490, doi:10.3762/bjnano.5.161

• impact of NPs that merits discussion. There is a big difference between the use of NPs for cellular labeling or biosensing studies in research, as opposed to any therapeutic (in vivo) utility, and the two should never be thought of together or directly compared. It was, for example, recently shown that

Nanocavity crossbar arrays for parallel electrochemical sensing on a chip

• Enno Kätelhön,
• Dirk Mayer,
• Marko Banzet,
• Andreas Offenhäusser and
• Bernhard Wolfrum

Beilstein J. Nanotechnol. 2014, 5, 1137–1143, doi:10.3762/bjnano.5.124

• sensors that are highly desirable for applications such as on-chip parallel biosensing or the detection of chemical communication in a neuronal network. This can be achieved via the organization of feed lines in a perpendicular arrangement. Individual sensors are then located at each of the feed line

In vitro toxicity and bioimaging studies of gold nanorods formulations coated with biofunctional thiol-PEG molecules and Pluronic block copolymers

• Tianxun Gong,
• Douglas Goh,
• Malini Olivo and
• Ken-Tye Yong

Beilstein J. Nanotechnol. 2014, 5, 546–553, doi:10.3762/bjnano.5.64

• ]. Furthermore, it is well reported that AuNRs are often used for surface enhanced Raman spectroscopy (SERS) biosensing applications. This is based on the observation that a gold rod-like particle has a higher electric field at both ends of the rod [10][11] where it is particularly useful for enhancing the

Dye-doped spheres with plasmonic semi-shells: Lasing modes and scattering at realistic gain levels

• Nikita Arnold,
• Boyang Ding,
• Calin Hrelescu and
• Thomas A. Klar

Beilstein J. Nanotechnol. 2013, 4, 974–987, doi:10.3762/bjnano.4.110

• used for important applications such as biosensing [18], plasmon-enhanced solar cells [19][20], or as substrates for surface-enhanced Raman scattering [21][22] and coherent anti-Stokes Raman scattering [23]. A severe problem for all plasmonic applications is the damping of plasmons due to Ohmic losses

Photocatalytic antibacterial performance of TiO₂ and Ag-doped TiO₂ against S. aureus. P. aeruginosa and E. coli

• Kiran Gupta,
• R. P. Singh,
• Ashutosh Pandey and
• Anjana Pandey

Beilstein J. Nanotechnol. 2013, 4, 345–351, doi:10.3762/bjnano.4.40

• photocatalytic efficiency [8][9]. However, silver nanoparticles have prospective applications including biosensing, biodiagnostics, optical fibers, and antimicrobial and photocatalytic uses. Silver ions are known to cause denaturation of proteins present in bacterial cell walls and slow down bacterial growth [5

FTIR nanobiosensors for Escherichia coli detection

• Stefania Mura,
• Gianfranco Greppi,
• Maria Laura Marongiu,
• Pier Paolo Roggero,
• Sandeep P. Ravindranath,
• Lisa J. Mauer,
• Nicoletta Schibeci,
• Francesco Perria,
• Massimo Piccinini,
• Plinio Innocenzi and
• Joseph Irudayaraj

Beilstein J. Nanotechnol. 2012, 3, 485–492, doi:10.3762/bjnano.3.55

• traditional devices into biosensing systems with high sensitivity. In particular, mesoporous titania thin films synthesized with the sol–gel method, were used to immobilize biomolecules (antibodies and pathogens) thanks to the high surface area due to their nano-organization, visible in a AFM image (Figure 1

Microfluidic anodization of aluminum films for the fabrication of nanoporous lipid bilayer support structures

• Jaydeep Bhattacharya,
• Alexandre Kisner,
• Andreas Offenhäusser and
• Bernhard Wolfrum

Beilstein J. Nanotechnol. 2011, 2, 104–109, doi:10.3762/bjnano.2.12

• as template structures in nanofabrication technology [9][10][11][12][13][14][15][16][17][18][19][20] to their direct use as functional interfaces for controlled release of molecules [21][22][23], co-culture development [24], or biosensing [25]. For example, Steinem et al. have demonstrated the

Magnetic nanoparticles for biomedical NMR-based diagnostics

• Huilin Shao,
• Tae-Jong Yoon,
• Monty Liong,
• Ralph Weissleder and
• Hakho Lee

Beilstein J. Nanotechnol. 2010, 1, 142–154, doi:10.3762/bjnano.1.17

• medicine. In general, biological samples have only negligible magnetic susceptibility. Thus, using magnetic nanoparticles for biosensing not only enhances sensitivity but also effectively reduces sample preparation needs. This review focuses on the use of magnetic nanoparticles for in vitro detection of

• molecular measurements into clinical settings, however, an assay would need to 1) provide high sensitivity and specificity, 2) minimize sample preparation and sample volume, and 3) ideally allow concurrent detection of diverse target moieties through multiplexed measurements. Biosensing strategies based on

• their longitudinal relaxivities (r1), T2 is used for NMR-based biosensing applications. With a higher r2 relaxivity, fewer numbers of nanoparticles are required to produce detectable T2 changes. Within an ensemble of MNPs, magnetic relaxation properties depend on more than simply the particles

Electrochemical behavior of dye-linked L-proline dehydrogenase on glassy carbon electrodes modified by multi-walled carbon nanotubes

• Haitao Zheng,
• Leyi Lin,
• Yosuke Okezaki,
• Ryushi Kawakami,
• Haruhiko Sakuraba,
• Toshihisa Ohshima,
• Keiichi Takagi and
• Shin-ichiro Suye

Beilstein J. Nanotechnol. 2010, 1, 135–141, doi:10.3762/bjnano.1.16

• require considerable time for analysis. In recent years, researchers have paid much more attention to the construction of electrochemical enzyme biosensors for the analysis of amino acids [5][6][7], and several electrochemical biosensing systems for L-proline and D-proline determination have been reported