Electron beam-based direct writing of nanostructures using a palladium β-ketoesterate complex

• Chinmai Sai Jureddy,
• Krzysztof Maćkosz,
• Aleksandra Butrymowicz-Kubiak,
• Iwona B. Szymańska,
• Patrik Hoffmann and
• Ivo Utke

Beilstein J. Nanotechnol. 2025, 16, 530–539, doi:10.3762/bjnano.16.41

• )2] [40][41]. The potential of growing 3D nanostructures with this precursor was also explored. The insights gained from this research could be valuable in the development of precursors tailored for FEBID. Experimental The structure of [Pd(tbaoac)2] is shown in Figure 1. The precursor was synthesized

Zeolite materials with Ni and Co: synthesis and catalytic potential in the selective hydrogenation of citral

• Inocente Rodríguez-Iznaga,
• Yailen Costa Marrero,
• Tania Farias Piñeira,
• Céline Fontaine,
• Lexane Paget,
• Beatriz Concepción Rosabal,
• Arbelio Penton Madrigal,
• Vitalii Petranovskii and
• Gwendoline Lafaye

Beilstein J. Nanotechnol. 2025, 16, 520–529, doi:10.3762/bjnano.16.40

• metallic species for various applications, leading to the invention of new functional materials for sustainable development, such as catalysts [1][2][3]. Among the various methods used to modify zeolites, ion exchange is the most widely employed. Different ion exchange methods are known, such as ion

• systems enables the creation of materials with enhanced properties compared to monocationic zeolites, which is crucial for the development of advanced catalysts and other materials [7][8][9][10]. Natural zeolites attract significant attention because of their abundance, low cost, non-toxic nature, and

N₂⁺-implantation-induced tailoring of structural, morphological, optical, and electrical characteristics of sputtered molybdenum thin films

• Usha Rani,
• Kafi Devi,
• Divya Gupta and
• Sanjeev Aggarwal

Beilstein J. Nanotechnol. 2025, 16, 495–509, doi:10.3762/bjnano.16.38

• nitrogen ion implantation on molybdenum thin films. They also examined the phase development and tribological alterations caused by ion implantation. Furthermore, Nakano et al. [26] investigated the deterioration of optical characteristics in polycrystalline Mo mirrors exposed to irradiation with helium or

• thickness and investigating the effects of these factors on the characteristics of molybdenum thin films. This study promotes the development of next-generation Mo thin films with precisely tuned characteristics. The findings of this research contribute to the optimization and development of Mo thin films

• thankful to the Ministry of Human Resources and Development (MHRD) for RUSA 2.0 grants to the Centre for Advanced Material Research (CAMR), Kurukshetra University, Kurukshetra.

Performance optimization of a microwave-coupled plasma-based ultralow-energy ECR ion source for silicon nanostructuring

• Joy Mukherjee,
• Safiul Alam Mollick,
• Tanmoy Basu and
• Tapobrata Som

Beilstein J. Nanotechnol. 2025, 16, 484–494, doi:10.3762/bjnano.16.37

• beam current varies with different ion energies [29][30]. This article focuses on optimizing the beam current generated by a cost-effective microwave-based ECR ion source and the subsequent development of nanoscale patterns on the surface of silicon. The relationship between the beam current and

• ripple structure, the power spectral density factor along the parallel and perpendicular direction of the developed ripples is presented in Figure 6g,h. The prominent peak present in Figure 6g indicates the development of the ripple structure along the x direction (parallel) with a particular wavevector

• surface reduces the reflection of UV–visible light because of light trapping by multiple reflections [47][48][49]. Ar-ion bombardment for 3 h leads to the development of a well-defined nanopattern on the silicon surface; hence, the reflectivity becomes minimal compared to the other two surfaces that were

Synthetic-polymer-assisted antisense oligonucleotide delivery: targeted approaches for precision disease treatment

• Ana Cubillo Alvarez,
• Dylan Maguire and
• Ruairí P. Brannigan

Beilstein J. Nanotechnol. 2025, 16, 435–463, doi:10.3762/bjnano.16.34

• oligomer (PMO); phosphorothioate (PS); polyplexes; ribose substitutions; small interfering RNA (siRNA); synthetic polymers; tricyclo-DNA (tcDNA); Introduction The development and use of personalised therapies tailored to individual patients have emerged as a powerful strategy for treating various

• patient-personalised therapies [41][42]. In 2019, Kim et al. pioneered the development of milasen, a ssASO drug tailored to a single patient affected by a rare form of Batten’s disease, and its clinical efficiency was successfully proven [43]. Despite significant progress in the discovery of novel

• in ASO-based therapies. Some promising strategies to overcome these limitations involve the conjugation of ASOs with peptides [53], polymers [54], aptamers [55], and antibodies [56], as well as the development of novel drug delivery systems [57][58]. This review discusses the challenges associated

Quantification of lead through rod-shaped silver-doped zinc oxide nanoparticles using an electrochemical approach

• Ravinder Lamba,
• Gaurav Bhanjana,
• Neeraj Dilbaghi,
• Vivek Gupta and
• Sandeep Kumar

Beilstein J. Nanotechnol. 2025, 16, 422–434, doi:10.3762/bjnano.16.33

• uncomplicated method for producing Ag@ZnO NRs. These fabricated Ag@ZnO NRs play an effective role as an electron mediator in the development of lead chemical sensors which are both highly sensitive and robust in nature. Based on our current understanding, the lead sensor we developed exhibits the most notable

Biomimetics and bioinspired surfaces: from nature to theory and applications

• Rhainer Guillermo Ferreira,
• Thies H. Büscher,
• Manuela Rebora,
• Poramate Manoonpong,
• Zhendong Dai and
• Stanislav N. Gorb

Beilstein J. Nanotechnol. 2025, 16, 418–421, doi:10.3762/bjnano.16.32

• mammals while addressing the functional fibrillar interfaces in biological hair. Presenting one applied example for biomimetic approaches, Ali et al. [7] used the hydrophobicity of the integument of spring tail (Collembola) as a template for the bioinspired development of nanofilament coatings that reduce

Size control of nanoparticles synthesized by pulsed laser ablation in liquids using donut-shaped beams

• Abdel Rahman Altakroury,
• Oleksandr Gatsa,
• Farbod Riahi,
• Zongwen Fu,
• Miroslava Flimelová,
• Andrei Samokhvalov,
• Stephan Barcikowski,
• Carlos Doñate-Buendía,
• Alexander V. Bulgakov and
• Bilal Gökce

Beilstein J. Nanotechnol. 2025, 16, 407–417, doi:10.3762/bjnano.16.31

• and have a relatively low degree of crystallinity compared to the original target (Figure S4, Supporting Information File 1). The crystalline to amorphous transition is likely due to the development of stresses induced by ultrafast heating and cooling during PLAL [53]. However, both oxidation and

• from the European Regional Development Fund and the State Budget of the Czech Republic (project SenDiSo No. CZ.02.01.01/00/22_008/0004596).

ReactorAFM/STM – dynamic reactions on surfaces at elevated temperature and atmospheric pressure

• Tycho Roorda,
• Hamed Achour,
• Matthijs A. van Spronsen,
• Marta E. Cañas-Ventura,
• Sander B. Roobol,
• Willem Onderwaater,
• Mirthe Bergman,
• Peter van der Tuijn,
• Gertjan van Baarle,
• Johan W. Bakker,
• Joost W. M. Frenken and
• Irene M. N. Groot

Beilstein J. Nanotechnol. 2025, 16, 397–406, doi:10.3762/bjnano.16.30

• these techniques are photon-based [4][5][6][7][8][9]. Even though they provide valuable insights, the development of surface-sensitive techniques that can image the catalyst at the atomic scale under high-pressure and high-temperature conditions remains crucial. In attempting to close the pressure gap

• AFM/STM reactor is the possibility to observe the structural and electronic properties of the surface at high gas pressures and temperatures, independent of its conductivity. The extension from STM-only and AFM-only to the combined AFM/STM reactor is an ongoing development of the existing ReactorSTM

Engineered PEG–PCL nanoparticles enable sensitive and selective detection of sodium dodecyl sulfate: a qualitative and quantitative analysis

• Soni Prajapati and
• Ranjana Singh

Beilstein J. Nanotechnol. 2025, 16, 385–396, doi:10.3762/bjnano.16.29

• , 190, 12, and 4 h of exposure, respectively [6]. The sub-lethal chronic effects of SDS were observed on the survival, metabolic processes, and development of juvenile Centropomus parallelus specimens exposed to the compound at three distinct salinity levels [7]. In vitro studies on bovine lenses at an

• absence of the Bradford reagent. This confirmed that both PEG–PCL NPs and the Bradford reagents need to be added to the ratio for the optical sensor development. PEG–PCL NPs and the Bradford reagent ratio was 2:3, giving maximum optical absorbance (Figure 4a). Similar results were obtained via

Development of a mucoadhesive drug delivery system and its interaction with gastric cells

• Ahmet Baki Sahin,
• Serdar Karakurt and
• Deniz Sezlev Bilecen

Beilstein J. Nanotechnol. 2025, 16, 371–384, doi:10.3762/bjnano.16.28

• effective in overcoming these obstacles, particularly regarding drugs that are designed for the treatment of local gastric diseases [3]. The solution to this is the development of gastroretentive drug delivery systems. These are designed to increase the drug residence time in the upper part of the

• system. The reason for choosing this peptide as a model drug was that there is ongoing research for the use of peptide-based therapeutics for the treatment of diseases; however, development of oral peptide therapy is quite challenging because of the high acidity in the stomach and the presence of the

• development of this assay was inspired by a study performed by Sarparanta and colleagues [79]. AGS cells were seeded on separate 12-well plates at two concentrations (6 × 104 and 1.2 × 105 cells/well) to analyze the increase in mucoadhesion with increasing cell concentrations. Next day, the medium was

Tailoring of physical properties of RF-sputtered ZnTe films: role of substrate temperature

• Kafi Devi,
• Usha Rani,
• Arun Kumar,
• Divya Gupta and
• Sanjeev Aggarwal

Beilstein J. Nanotechnol. 2025, 16, 333–348, doi:10.3762/bjnano.16.25

• substrate, which ultimately lead to the development of stress and strain within the film. At a substrate temperature of 600 °C, the lattice constant value is the same as in the bulk material. The strain in films occurs due to lattice mismatch between film and bulk. The microstrain in films was calculated

• accelerator and related characterization facilities at Kurukshetra University. The authors are also thankful to the Ministry of Human Resource and Development (MHRD), New Delhi for RUSA 2.0 grants to the Center for Advanced Material Research (CAMR), Kurukshetra University.

Graphene oxide–chloroquine conjugate induces DNA damage in A549 lung cancer cells through autophagy modulation

• Braham Dutt Arya,
• Sandeep Mittal,
• Prachi Joshi,
• Alok Kumar Pandey,
• Jaime E. Ramirez-Vick,
• Govind Gupta and
• Surinder P. Singh

Beilstein J. Nanotechnol. 2025, 16, 316–332, doi:10.3762/bjnano.16.24

• .16.24 Abstract Autophagy is a highly regulated catabolic process by which unnecessary, dysfunctional, or damaged proteins and other cellular components are degraded and recycled to promote cellular differentiation, survival, and development. In response to endogenous or exogenous stresses, cancer cells

Fabrication and evaluation of BerNPs regarding the growth and development of Streptococcus mutans

• Tuyen Huu Nguyen,
• Hong Thanh Pham,
• Kieu Kim Thanh Nguyen,
• Loan Hong Ngo,
• Anh Ngoc Tuan Mai,
• Thu Hoang Anh Lam,
• Ngan Thi Kim Phan,
• Dung Tien Pham,
• Duong Thuy Hoang,
• Thuc Dong Nguyen and
• Lien Thi Xuan Truong

Beilstein J. Nanotechnol. 2025, 16, 308–315, doi:10.3762/bjnano.16.23

• materials with novel properties. The development of substances and methods with enhanced water dispersibility and bioavailability from materials such as berberine and curcumin is a current trend. Several studies on the nanofabrication of berberine aimed at improving its bioavailability and evaluating its

• ranging from 12.5 to 25.0 µg/mL [31]. However, there is limited research on the activity of BerNPs against S. mutans, a primary pathogen responsible for dental caries. This study aims to provide additional information on the potential and applications of BerNPs in the development of oral care products

• , and ldh, thereby preventing biofilm development [40]. Conclusion In this study, BerNPs were fabricated using ball milling with zirconium balls. Analysis through FE-SEM, UV–vis, XRD, and FTIR revealed that the nanoparticles predominantly exhibited a crystalline structure, with an average size of 40–65

Enhancing mechanical properties of chitosan/PVA electrospun nanofibers: a comprehensive review

• Nur Areisman Mohd Salleh,
• Amalina Muhammad Afifi,
• Fathiah Mohamed Zuki and
• Hanna Sofia SalehHudin

Beilstein J. Nanotechnol. 2025, 16, 286–307, doi:10.3762/bjnano.16.22

• directions are proposed to overcome these obstacles and further enhance the mechanical properties of chitosan/PVA electrospun nanofibers, guiding their development for practical applications. Keywords: biomaterials; chitosan; electrospun nanofiber; mechanical properties; polyvinyl alcohol; Introduction In

• nanocomposites have been produced through the substantial utilization of nanoparticles. The development of fibrous nanocomposites or bio-nanocomposites, where the matrix and/or fillers are biomaterials, has been advanced in recent years by introducing nanoscale materials into electrospun fibers in the form of

Emerging strategies in the sustainable removal of antibiotics using semiconductor-based photocatalysts

• Yunus Ahmed,
• Keya Rani Dutta,
• Parul Akhtar,
• Md. Arif Hossen,
• Md. Jahangir Alam,
• Obaid A. Alharbi,
• Hamad AlMohamadi and
• Abdul Wahab Mohammad

Beilstein J. Nanotechnol. 2025, 16, 264–285, doi:10.3762/bjnano.16.21

• continuous presence of antibiotics in natural environments can contribute to the development of antibiotic-resistant bacteria (ARBs) and their resistance genes (ARGs), hastening the spread of antibiotic resistance [9][10]. Several studies have reported that this situation poses significant risks to human

• enable localized surface plasmonic resonance (LSPR). The second strategy focuses on the development of heterojunctions between two semiconductors that is activated by visible light [65][66]. These heterojunctions should have bandgaps and energy levels that match the valence and conduction bands

• efficiency in comparison to α-Bi2O3. Nevertheless, the inherent instability of β-Bi2O3 presents a formidable obstacle in the development of uncomplicated techniques for producing pure β-Bi2O3, particularly at the nanoscale. The photocatalytic efficiency of Bi2O3 is inadequate for decomposing antibiotics

Synthesis and the impact of hydroxyapatite nanoparticles on the viability and activity of rhizobacteria

• Bedah Rupaedah,
• Indrika Novella,
• Atiek Rostika Noviyanti,
• Diana Rakhmawaty Eddy,
• Anna Safarrida,
• Abdul Hapid,
• Zhafira Amila Haqqa,
• Suryana Suryana,
• Irwan Kurnia and
• Fathiyah Inayatirrahmi

Beilstein J. Nanotechnol. 2025, 16, 216–228, doi:10.3762/bjnano.16.17

• maintain their viability over time [4]. Consequently, the characteristics of the carrier material used to transport rhizobacteria are critical in determining their survival and successful colonization within both soil and root systems. This, in turn, contributes to the development of biofertilizers as a

• application and storage [7]. Nanomaterials have gained significant attention in the development of rhizobacterial carrier materials, as their effective utilization can provide protective benefits to plants, assist in nutrient absorption, and, when in gel form, significantly improve water management efficiency

Recent advances in photothermal nanomaterials for ophthalmic applications

• Jiayuan Zhuang,
• Linhui Jia,
• Chenghao Li,
• Rui Yang,
• Jiapeng Wang,
• Wen-an Wang,
• Heng Zhou and
• Xiangxia Luo

Beilstein J. Nanotechnol. 2025, 16, 195–215, doi:10.3762/bjnano.16.16

• treatment technologies. This underscores an urgent need for more advanced therapeutic approaches to effectively halt or even reverse the progression of eye diseases. The rapid advancement of nanotechnology offers promising pathways for the development of novel ophthalmic therapies. Notably, photothermal

• treatments pose significant barriers [5]. The evolution of nanotechnology has catalyzed the development of novel therapeutic technologies, with a plethora of nanomaterials exhibiting significant potential for nanotherapeutic applications [6][7][8]. Among these, photothermal nanomaterials hold promise in

• photothermal conversion and tunability of light absorption of these materials simplify the therapeutic light source, broadening their applicability [17][18]. Furthermore, the customizable nature of these nanomaterials allows for the development of personalized treatment plans, tailored to individual patient

Probing the potential of rare earth elements in the development of new anticancer drugs: single molecule studies

• Josiane A. D. Batista,
• Rayane M. de Oliveira,
• Carlos H. M. Lima,
• Milton L. Lana Júnior,
• Virgílio C. dos Anjos,
• Maria J. V. Bell and
• Márcio S. Rocha

Beilstein J. Nanotechnol. 2025, 16, 187–194, doi:10.3762/bjnano.16.15

• , Minas Gerais, Brazil Departamento de Ciências Naturais, Universidade Federal do Acre, Rio Branco, Acre, Brazil 10.3762/bjnano.16.15 Abstract We use optical tweezers and atomic force microscopy to investigate the potential of rare earth elements to be used as anticancer agents in the development of new

• what occurs with classical DNA condensing agents such as polycations and depletants. Keywords: DNA; optical tweezers; rare earth elements; single molecule force spectroscopy; Introduction The development of new drugs to treat human diseases is a field of singular importance that usually involves

• side effects related to these therapies. Actually, both aspects depend on the development of new drugs and/or drug carriers that can improve the selectivity of these anticancer agents to reach their specific targets inside tumor cells [3][4][5]. Although commonly used in a number of technological

A review of metal-organic frameworks and polymers in mixed matrix membranes for CO₂ capture

• Charlotte Skjold Qvist Christensen,
• Nicholas Hansen,
• Mahboubeh Motadayen,
• Nina Lock,
• Martin Lahn Henriksen and
• Jonathan Quinson

Beilstein J. Nanotechnol. 2025, 16, 155–186, doi:10.3762/bjnano.16.14

• membranes. To address this challenge, the development of mixed matrix membranes (MMMs) is a promising strategy. MMMs are obtained by carefully integrating porous nano-fillers into polymeric matrices, enabling the simultaneous enhancement of selectivity and permeability. In particular, metal-organic

• opportunities encountered in the development and fabrication of MOF-based MMMs for CO2 capture. An account of current trends in the field is given, while gaps and further areas of investigation are identified and highlighted. Specifically, the review intends to convey a broad yet comprehensive understanding of

• of their outstanding gas adsorption capabilities [30][45]. The topic of MOF-based gas separation and CO2 capture has been extensively addressed in comprehensive reviews [26][46][47][48][49]. A succinct account of MOF development for CO2 capture is proposed in the next paragraphs to better understand

Clays enhanced with niobium: potential in wastewater treatment and reuse as pigment with antibacterial activity

• Silvia Jaerger,
• Patricia Appelt,
• Mario Antônio Alves da Cunha,
• Fabián Ccahuana Ayma,
• Ricardo Schneider,
• Carla Bittencourt and
• Fauze Jacó Anaissi

Beilstein J. Nanotechnol. 2025, 16, 141–154, doi:10.3762/bjnano.16.13

• purifying water contaminated with dyes necessitating the development of cost-effective technologies for their removal from industrial effluents. Adsorption emerges as a widely used method for pollutant removal from wastewater due to its design simplicity, operational ease, and relatively straightforward

• ) demonstrate significant antibacterial activity against the Gram-negative bacteria Proteus mirabilis, highlighting the influence of the dye in the assay outcomes. The implications of this work extend to the development of a novel hybrid pigment. This pigment, synthesized from abundant natural clays of the

TiO₂ immobilized on 2D mordenite: effect of hydrolysis conditions on structural, textural, and optical characteristics of the nanocomposites

• Marina G. Shelyapina,
• Rosario Isidro Yocupicio-Gaxiola,
• Gleb A. Valkovsky and
• Vitalii Petranovskii

Beilstein J. Nanotechnol. 2025, 16, 128–140, doi:10.3762/bjnano.16.12

• SiO2 opens up a wide range of opportunities for the development of new materials for specific applications. Experimental The synthesis of nanocomposites was carried out similarly to the method first proposed in [49] and used previously in [5][50] for the insertion of SiO2 nanopillars. The latter

Comparison of organic and inorganic hole transport layers in double perovskite material-based solar cell

• Deepika K and
• Arjun Singh

Beilstein J. Nanotechnol. 2025, 16, 119–127, doi:10.3762/bjnano.16.11

• their applicability to practical device development. Conclusion Solar energy is one of the most promising renewable energy sources. It is one of those energy sources creating no harmful emissions. PSCs are a new generation in the photovoltaic industry. Here, a La2NiMnO6 (LNMO)-based DPSC is simulated

Nanocarriers and macrophage interaction: from a potential hurdle to an alternative therapeutic strategy

• Naths Grazia Sukubo,
• Paolo Bigini and
• Annalisa Morelli

Beilstein J. Nanotechnol. 2025, 16, 97–118, doi:10.3762/bjnano.16.10

• .16.10 Abstract In the coming decades, the development of nanocarriers (NCs) for targeted drug delivery will mark a significant advance in the field of pharmacology. NCs can improve drug solubility, ensure precise distribution, and enable passage across biological barriers. Despite these potential

• nanomedicine landscape, the design and development of nanocarriers (NCs) for precise drug delivery are a pivotal innovation. NCs address significant pharmacological challenges, such as enhancing drug solubility, ensuring specific distribution, and facilitating the crossing of biological barriers [1]. Tailoring

• Hepatocellular carcinoma (HCC): HCC is the most common type of primary liver cancer and represents a significant global health burden [96]. The development of HCC is a complex, multistep process that involves genetic mutations, epigenetic alterations, and changes in the liver microenvironment. The prognosis for

Characterization of ZnO nanoparticles synthesized using probiotic Lactiplantibacillus plantarum GP258

• Prashantkumar Siddappa Chakra,
• Aishwarya Banakar,
• Shriram Narayan Puranik,
• Vishwas Kaveeshwar,
• C. R. Ravikumar and
• Devaraja Gayathri

Beilstein J. Nanotechnol. 2025, 16, 78–89, doi:10.3762/bjnano.16.8

• applications. Keywords: anticancer; green synthesis; lactic acid bacteria; nanoparticles; zinc oxide; Introduction Nanotechnology has revolutionized various fields through its remarkable development and the unique properties exhibited by nanoparticles (NPs) at the mesoscopic level. Dimension, form, surface

• 0.1 M ZnSO4·7H2O was added, and the flask was heated to 80 °C for 10 min. The continuous process of transformation could be confirmed by the development of white precipitate at the bottom of the flask. After that, the flask was incubated for a further 12 h at 37 °C to ensure complete particle