Deep-learning recognition and tracking of individual nanotubes in low-contrast microscopy videos

• Vladimir Pimonov,
• Said Tahir and
• Vincent Jourdain

Beilstein J. Nanotechnol. 2025, 16, 1316–1324, doi:10.3762/bjnano.16.96

• growth kinetics, revealing complex behaviors such as intermittent switching between growth, pause, and etching modes, even under nominally constant synthesis conditions [20]. These observations, further supported by complementary Raman spectroscopy, served as a foundation for the development of a new

Enhancing the photoelectrochemical performance of BiOI-derived BiVO₄ films by controlled-intensity current electrodeposition

• Huu Phuc Dang,
• Khanh Quang Nguyen,
• Nguyen Thi Mai Tho and
• Tran Le

Beilstein J. Nanotechnol. 2025, 16, 1289–1301, doi:10.3762/bjnano.16.94

• samples fabricated with lower current density, highlighting the benefits of the optimized electrodeposition conditions for the former. Keywords: BiOI; BiVO4; electrodeposition; photoelectrochemical water splitting; Introduction In the context of the increasing global energy demand, the development of

Acrocomia aculeata oil-loaded nanoemulsion: development, anti-inflammatory properties, and cytotoxicity evaluation

• Verónica Bautista-Robles,
• Hady Keita,
• Edgar Julián Paredes Gamero,
• Layna Tayná Brito Leite,
• Jessica de Araújo Isaías Muller,
• Mônica Cristina Toffoli Kadri,
• Ariadna Lafourcade Prada and
• Jesús Rafael Rodríguez Amado

Beilstein J. Nanotechnol. 2025, 16, 1277–1288, doi:10.3762/bjnano.16.93

• ]. Despite these variations, the compositional profiles remain comparable, underscoring the distinctive chemical characteristics of the oil studied. Preparation of nanoemulsions, required hydrophilic–lipophilic balance, droplet size, zeta potential, and shelf stability The development of a nanoemulsion

• Acrocomia aculeata oil-loaded nanoemulsion as a nanotechnological innovative product that enhances the therapeutic value of A. aculeata oil and supports its development as a promising anti-inflammatory agent. Experimental Materials Bocaiúva oil was used as the lipid core (relative density 0.9000, iodine

Better together: biomimetic nanomedicines for high performance tumor therapy

• Imran Shair Mohammad,
• Gizem Kursunluoglu,
• Anup Kumar Patel,
• Hafiz Muhammad Ishaq,
• Cansu Umran Tunc,
• Dilek Kanarya,
• Mubashar Rehman,
• Omer Aydin and
• Yin Lifang

Beilstein J. Nanotechnol. 2025, 16, 1246–1276, doi:10.3762/bjnano.16.92

• targetability have been employed for the treatment of various fatal diseases such as cancer, Alzheimer’s, stroke, and diabetes [17][18][19]. However, the development of optimum NP drug carriers is still critical as they all come with several limitations. For example, liposomes can carry hydrophilic drugs that

• different steps of a metabolic pathway [100]. Later, this strategy has evolved into the development of artificial organelles, which contain enzymes for a complex cascade reaction. Artificial organelles consist of capsosomes with a polymeric shell containing multiple liposomes, where each liposome may carry

• delivery [115]. Excellent control of shape, size, and genetic modification makes virus-like particles an excellent opportunity for safe and effective delivery of payload to an intended site. 2 Biomedical applications of biomimetic nanoparticles 2.1 Chemotherapy In recent years, the development of novel

Hydrogels and nanogels: effectiveness in dermal applications

• Jéssica da Cruz Ludwig,
• Diana Fortkamp Grigoletto,
• Daniele Fernanda Renzi,
• Wolf-Rainer Abraham,
• Daniel de Paula and
• Najeh Maissar Khalil

Beilstein J. Nanotechnol. 2025, 16, 1216–1233, doi:10.3762/bjnano.16.90

• have emerged as promising alternatives for various medical purposes, including skin [7], nasal [4], and eye [8] applications. The evolution of ocular contact lenses, for example, has benefited from the development of hydrogels [9][10]. Hydrogels can be described as cross-linked polymeric networks

• prevention of the spontaneous combustion of coal [29]. The development of chemically functional materials on the nanoscale appears to be of fundamental importance when it comes to health applications. Nanogels are an excellent alternative for the manufacture of biomaterials due to their physical and chemical

• encapsulation of poorly water-soluble drugs and allowing the controlled release of the encapsulated compound [142][144]. These innovations represent a significant advance in the development of multifunctional and biocompatible nanogels, suitable for applications in oncology, gene therapy, and precision medicine

Investigation of the solubility of protoporphyrin IX in aqueous and hydroalcoholic solvent systems

• Michelly de Sá Matsuoka,
• Giovanna Carla Cadini Ruiz,
• Marcos Luciano Bruschi and
• Jéssica Bassi da Silva

Beilstein J. Nanotechnol. 2025, 16, 1209–1215, doi:10.3762/bjnano.16.89

• evaluate the solubility of PpIX in distinct solvent systems to support the development of novel pharmaceutical formulations. The shake-flask method was employed, using purified water, 50% ethanol (EtOH50), 77% ethanol (EtOH77), absolute ethanol (EtOHabs), and polymeric systems containing 10% (w/w

• its bioavailability and light absorption capacity will be increased [5]. To overcome this problem, the development of drug delivery systems, such as poloxamer-based ones, has played an important role on the delivery of dyes for PDT [8][9][10]. Poloxamers are triblock copolymers with thermosensitive

• optimize the development of new drug delivery systems for PDT applications. Moreover, the potential of P407 as a feasible system for PpIX delivery was also evaluated in different media. Experimental Preparation of the systems The systems were prepared at least 24 h before the test and used for up to seven

Chitosan nanocomposite containing rotenoids: an alternative bioinsecticidal approach for the management of Aedes aegypti

• Maria A. A. Bertonceli,
• Vitor D. C. Cristo,
• Ivo J. Vieira,
• Francisco J. A. Lemos,
• Arnoldo R. Façanha,
• Raimundo Braz-Filho,
• Gustavo V. T. Batista,
• Luis G. M. Basso,
• Sérgio H. Seabra,
• Thalya S. R. Nogueira,
• Felipe F. Moreira,
• Arícia L. E. M. Assis,
• Antônia E. A. Oliveira and
• Kátia V. S. Fernandes

Beilstein J. Nanotechnol. 2025, 16, 1197–1208, doi:10.3762/bjnano.16.88

• significant advancement, vector management remains the primary strategy for preventing these urban arboviruses. In this context, the development of pesticides that offer safer alternatives for the environment and human health has become urgent. In this study, a chitosan-based nanocomposite was developed as a

• investment of 16.9 million Brazilian reais in 2023 [4], the development of resistance by this vector to regularly used larvicides, which impact other organisms beneficial to the environment while presenting risks of poisoning to humans who handle them, is rampant. The adoption of new biotechnological tools

• limited regulatory restrictions imposed on the use of these insecticides. The development of pesticides that provide safer alternatives for both the environment and human health is an urgent need [8]. Thus, the nanocomposite developed in this study holds promising potential for the formulation of new

Crystalline and amorphous structure selectivity of ignoble high-entropy alloy nanoparticles during laser ablation in organic liquids is set by pulse duration

• Robert Stuckert,
• Felix Pohl,
• Oleg Prymak,
• Ulrich Schürmann,
• Christoph Rehbock,
• Lorenz Kienle and
• Stephan Barcikowski

Beilstein J. Nanotechnol. 2025, 16, 1141–1159, doi:10.3762/bjnano.16.84

• ][93][94] while a recent review also thoroughly reported on the by-product development due to radical recombination during laser-based syntheses in organic solvents [54]. These carbon species can interact with the plume and diffuse into the nanoparticles, depending on the affinity of nanoparticle

• alloy nanoparticles is a prerequisite for further development of nanomaterial fabrication methods for applications in heterogeneous catalysis and magnetism. This suitability has been shown in earlier studies for high-entropy alloy nanoparticles, including laser-generated HEA NPs, in the application

Towards a quantitative theory for transmission X-ray microscopy

• James G. McNally,
• Christoph Pratsch,
• Stephan Werner,
• Stefan Rehbein,
• Andrew Gibbs,
• Jihao Wang,
• Thomas Lunkenbein,
• Peter Guttmann and
• Gerd Schneider

Beilstein J. Nanotechnol. 2025, 16, 1113–1128, doi:10.3762/bjnano.16.82

• . In the current study, we continue this effort toward further development of 3D models for TXMs. First, we introduce Mie theory as an alternate approach for light propagation through the sample. Mie theory provides an exact solution to Maxwell’s equations but limited to spheres of known refractive

Influence of ion beam current on the structural, optical, and mechanical properties of TiO₂ coatings: ion beam-assisted vs conventional electron beam evaporation

• Agata Obstarczyk and
• Urszula Wawrzaszek

Beilstein J. Nanotechnol. 2025, 16, 1097–1112, doi:10.3762/bjnano.16.81

• , and good availability, TiO2 in the form of thin films is now widely used in the development of gas sensors, photodetectors, solar cells, memristors, and photocatalysts [1][12][15][16][17]. The area of application of titanium dioxide is also related to the crystal structure in which it occurs, that is

Single-layer graphene oxide film grown on α-Al₂O₃(0001) for use as an adsorbent

• Shiro Entani,
• Mitsunori Honda,
• Masaru Takizawa and
• Makoto Kohda

Beilstein J. Nanotechnol. 2025, 16, 1082–1087, doi:10.3762/bjnano.16.79

• Shiro Entani Mitsunori Honda Masaru Takizawa Makoto Kohda Quantum Materials and Applications Research Center, National Institutes for Quantum Science and Technology, Takasaki, Gunma 370-1292, Japan Honda’s Lab for Development of Future Clay Materials Research, Japan Atomic Energy Agency, Tokai

• were conducted into its adsorption properties. A significant accident at a nuclear facility can result in the release of substantial amounts of radioactive cesium (Cs) and strontium (Sr) into the environment [19][20]. The development of a method for reducing the volume of these radioactive waste is

Soft materials nanoarchitectonics: liquid crystals, polymers, gels, biomaterials, and others

• Katsuhiko Ariga

Beilstein J. Nanotechnol. 2025, 16, 1025–1067, doi:10.3762/bjnano.16.77

• materials systems. It can be reasonably proposed that the mastery of materials science in the context of soft functional materials will facilitate the development of advanced functional systems that emulate the characteristics of living organisms. This concept is not limited to applications in biology, such

• the synthesis of covalent organic frameworks via polymer chemistry [70][71][72][73][74]. In particular, some thin-film techniques based on interface science are useful for the deliberate and rational assembly of ordered aggregated membrane structures. This is exemplified by the development of methods

• development of more sophisticated functional materials. Concurrently with the transition from hard to soft, there is also a significant trend in the advancement of materials sciences from the macroscale to the nanoscale. In other words, the ability to control the structures of materials at the nanoscale (i.e

Time-resolved probing of laser-induced nanostructuring processes in liquids

• Maximilian Spellauge,
• David Redka,
• Mianzhen Mo,
• Changyong Song,
• Heinz Paul Huber and
• Anton Plech

Beilstein J. Nanotechnol. 2025, 16, 968–1002, doi:10.3762/bjnano.16.74

• deformations caused by thermally excited elastic strains. However, stroboscopic measurements like these are limited to systems that recover their original states after perturbation and are unsuitable for studying irreversible kinetic reactions in strongly driven non-equilibrium phenomena. The development of

• comprehension of these intricate processes. The development of new large-scale facilities is actively underway through international collaboration. This progress will significantly enhance accessibility for researchers from diverse fields, extending beyond X-ray or electron scattering, and provide a versatile

• scattering studies with the use of electrons have been hindered by their shallow penetration depth (<1 μm) compared to that of hard X-rays (>100 μm). Recently, the development of free-flowing liquid sheet jets has overcome this limitation by providing flat liquid sheets with thicknesses down to tens of

Synthesis of biowaste-derived carbon-dot-mediated silver nanoparticles and the evaluation of electrochemical properties for supercapacitor electrodes

• Navya Kumari Tenkayala,
• Chandan Kumar Maity,
• Md Moniruzzaman and
• Subramani Devaraju

Beilstein J. Nanotechnol. 2025, 16, 933–943, doi:10.3762/bjnano.16.71

• density, quick charge/discharge capacity, and an outstanding retention rate. Nanocarbons are the appropriate candidates for EDLCs due to their high surface charge-storage ability and high conductivity [8][9][10]. The development of electrode materials with an efficient EDLC and pseudocapacitor properties

Focused ion beam-induced platinum deposition with a low-temperature cesium ion source

• Thomas Henning Loeber,
• Bert Laegel,
• Meltem Sezen,
• Feray Bakan Misirlioglu,
• Edgar J. D. Vredenbregt and
• Yang Li

Beilstein J. Nanotechnol. 2025, 16, 910–920, doi:10.3762/bjnano.16.69

• are more advanced with respect to source development because of their relatively low requirements regarding the cooling laser. Milling [10] as well as induced deposition of platinum (Pt) [11] and tungsten (W) [12] have been studied for a prototype FIB with an ultracold Rb+source. Further, a Cs+ laser

Heat-induced transformation of nickel-coated polycrystalline diamond film studied in situ by XPS and NEXAFS

• Olga V. Sedelnikova,
• Yuliya V. Fedoseeva,
• Dmitriy V. Gorodetskiy,
• Yuri N. Palyanov,
• Elena V. Shlyakhova,
• Eugene A. Maksimovskiy,
• Anna A. Makarova,
• Lyubov G. Bulusheva and
• Aleksandr V. Okotrub

Beilstein J. Nanotechnol. 2025, 16, 887–898, doi:10.3762/bjnano.16.67

• , resulting in the development of a thin sp² carbon layer over the entire surface of the sample. The chemical state of nickel in the annealed Ni-PCD film was elucidated using XPS and NEXAFS spectroscopy to probe the local environment of metal atoms on the surface and inside the bulk (Figure 3). The XPS Ni 3p

Synchrotron X-ray photoelectron spectroscopy study of sodium adsorption on vertically arranged MoS₂ layers coated with pyrolytic carbon

• Alexander V. Okotrub,
• Anastasiya D. Fedorenko,
• Anna A. Makarova,
• Veronica S. Sulyaeva,
• Yuliya V. Fedoseeva and
• Lyubov G. Bulusheva

Beilstein J. Nanotechnol. 2025, 16, 847–859, doi:10.3762/bjnano.16.64

• film, and annealing of the sodiated sample restores its structure. The obtained results demonstrate the important role of the graphitic coating in the development of viable MoS2-based electrodes for energy storage systems. Keywords: graphitic coating; molybdenum disulfide film; Na adsorption

Synthesis and magnetic transitions of rare-earth-free Fe–Mn–Ni–Si-based compositionally complex alloys at bulk and nanoscale

• Shabbir Tahir,
• Tatiana Smoliarova,
• Carlos Doñate-Buendía,
• Michael Farle,
• Natalia Shkodich and
• Bilal Gökce

Beilstein J. Nanotechnol. 2025, 16, 823–836, doi:10.3762/bjnano.16.62

• temperature ranges, such as room-temperature cooling and cryogenic systems [3][4]. The magnetic transition also plays a critical role in the development of temperature-sensitive magnetic sensors and actuators [5][6]. These devices harness the abrupt change in magnetic properties at Tc to detect temperature

• potential to replace rare earth elements in magnetic materials [18]. The development of rare-earth-free or rare-earth-lean magnets is critical because of the economic, environmental, and supply chain challenges associated with rare earth elements [19][20]. For instance, mining and processing of rare earths

Thickness dependent oxidation in CrCl₃: a scanning X-ray photoemission and Kelvin probe microscopies study

• Shafaq Kazim,
• Rahul Parmar,
• Maryam Azizinia,
• Matteo Amati,
• Muhammad Rauf,
• Andrea Di Cicco,
• Seyed Javid Rezvani,
• Dario Mastrippolito,
• Luca Ottaviano,
• Tomasz Klimczuk,
• Luca Gregoratti and
• Roberto Gunnella

Beilstein J. Nanotechnol. 2025, 16, 749–761, doi:10.3762/bjnano.16.58

• oxidation or the introduction of surface vacancies, a novel and versatile approach is unveiled for the development of low-dimensional multifunctional nanodevices. Keywords: chemical mapping; CrX3; Kelvin probe force microscopy; mechanical exfoliation; scanning photoelectron microscopy (SPEM); two

Serum heat inactivation diminishes ApoE-mediated uptake of D-Lin-MC3-DMA lipid nanoparticles

• Demian van Straten,
• Luuk van de Schepop,
• Rowan Frunt,
• Pieter Vader and
• Raymond M. Schiffelers

Beilstein J. Nanotechnol. 2025, 16, 740–748, doi:10.3762/bjnano.16.57

• protein corona formation in vitro and prevent bias in LNP development. Keywords: apolipoprotein E; fetal calf serum; heat inactivation; lipid nanoparticle; protein corona; Introduction Nanotechnology has gained a strong foothold in the field of drug delivery, having significant promise to overcome the

• a crucial part during pre-clinical nanoparticle development. The influence of the protein corona is particularly evident for the efficacy of lipid nanoparticles used for RNA delivery. Lipid nanoparticles (LNPs) protect the encapsulated RNA from premature clearance and simultaneously facilitate the

• delivery efficiency, it is becoming increasingly clear that the in vivo environment to which the nanoparticles will be exposed should be considered during LNP development. Nevertheless, the initial screening of nanoparticles in vitro is often restricted to experiments using tissue culture media

Synthesis of a multicomponent cellulose-based adsorbent for tetracycline removal from aquaculture water

• Uyen Bao Tran,
• Ngoc Thanh Vo-Tran,
• Khai The Truong,
• Dat Anh Nguyen,
• Quang Nhat Tran,
• Huu-Quang Nguyen,
• Jaebeom Lee and
• Hai Son Truong-Lam

Beilstein J. Nanotechnol. 2025, 16, 728–739, doi:10.3762/bjnano.16.56

• . These limitations have spurred the development of more effective and versatile adsorbents. Modern adsorbents are available in diverse compositions. Moreover, they are easy to manufacture and generally both cost-effective and environmentally friendly. Cellulose-based adsorbents, in particular, have

• efficiency, eco-friendliness, versatility, and up to 70% removal efficiency of tetracyline, oxytetracycline, chlortetracycline, and doxycycline, the synthesized PGC material shows great potential for addressing environmental challenges and promoting sustainable development. The PGC adsorbent, with higher

Efficiency of single-pulse laser fragmentation of organic nutraceutical dispersions in a circular jet flow-through reactor

• Tina Friedenauer,
• Maximilian Spellauge,
• Alexander Sommereyns,
• Verena Labenski,
• Tuba Esatbeyoglu,
• Christoph Rehbock,
• Heinz P. Huber and
• Stephan Barcikowski

Beilstein J. Nanotechnol. 2025, 16, 711–727, doi:10.3762/bjnano.16.55

• School in Advanced Optical Technologies (SAOT), Friedrich-Alexander-Universität Erlangen-Nürnberg, Paul-Gordan-Strasse 6, Erlangen 91052, Germany Department of Molecular Food Chemistry and Food Development, Institute of Food and One Health, Gottfried Wilhelm Leibniz University Hannover, Am Kleinen Felde

Nanostructured materials characterized by scanning photoelectron spectromicroscopy

• Matteo Amati,
• Alexey S. Shkvarin,
• Alexander I. Merentsov,
• Alexander N. Titov,
• María Taeño,
• David Maestre,
• Sarah R. McKibbin,
• Zygmunt Milosz,
• Ana Cremades,
• Rainer Timm and
• Luca Gregoratti

Beilstein J. Nanotechnol. 2025, 16, 700–710, doi:10.3762/bjnano.16.54

• devices, which include the synthesis, characterization, and processing, are part of an emerging and rapidly growing field referred to as nanotechnology. However, despite the large efforts of the scientific and industrial communities in the development of new nanostructured materials and related

• corresponding CL spectrum. XPS measurements provide valuable information on the electronic structure and properties of the NiO samples, which strongly support the development of potential applications including gas sensors and optical resonators [43][47]. Conclusion SPEM is a synchrotron-based technique

• surface chemical changes, local charging, and space-charge effects. To partially mitigate this effects, strong efforts must be spent in the development of new photoelectron detection systems capable of collecting the majority of electrons, currently wasted due to the limited acceptance angles of

High-temperature epitaxial growth of tantalum nitride thin films on MgO: structural evolution and potential for SQUID applications

• Michelle Cedillo Rosillo,
• Oscar Contreras López,
• Jesús Antonio Díaz,
• Agustín Conde Gallardo and
• Harvi A. Castillo Cuero

Beilstein J. Nanotechnol. 2025, 16, 690–699, doi:10.3762/bjnano.16.53

• as lossless power transmission, magnetic levitation in transportation systems, and the creation of powerful electromagnets. Furthermore, superconductivity plays a pivotal role in the development of advanced technologies, including quantum computing and nanometric electronic devices. Despite

• significant progress, a major challenge remains in discovering materials that exhibit superconductivity at higher, more practical temperatures. The efficient fabrication of materials with a low superconducting energy gap and an intermediate Tc is crucial for the development and enhancement of superconducting

• temperature on the structural evolution of TaN thin films deposited on MgO(100) substrates was investigated using XRD and TEM. Figure 3 shows the XRD patterns of TaN films deposited at various temperatures, revealing critical insights into phase development, crystallinity, and epitaxial growth as the

Aprepitant-loaded solid lipid nanoparticles: a novel approach to enhance oral bioavailability

• Mazhar Hussain,
• Muhammad Farooq,
• Muhammad Asad Saeed,
• Muhammad Ijaz,
• Sherjeel Adnan,
• Zeeshan Masood,
• Muhammad Waqas,
• Wafa Ishaq and
• Nabeela Ameer

Beilstein J. Nanotechnol. 2025, 16, 652–663, doi:10.3762/bjnano.16.50

• , Robert Stevenson Road, Edinburgh, EH9 3FB, United Kingdom 10.3762/bjnano.16.50 Abstract Objectives of the present study are the development of aprepitant (APT)-loaded solid lipid nanoparticles (SLNs) using the polymers poloxamer 407 and β-cyclodextrin for enhanced solubility and their pharmacokinetic