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Search for "dosage" in Full Text gives 92 result(s) in Beilstein Journal of Nanotechnology.

CdSe nanorod/TiO2 nanoparticle heterojunctions with enhanced solar- and visible-light photocatalytic activity

  • Fakher Laatar,
  • Hatem Moussa,
  • Halima Alem,
  • Lavinia Balan,
  • Emilien Girot,
  • Ghouti Medjahdi,
  • Hatem Ezzaouia and
  • Raphaël Schneider

Beilstein J. Nanotechnol. 2017, 8, 2741–2752, doi:10.3762/bjnano.8.273

Graphical Abstract
  • TiO2 and CdSe/TiO2 composites loaded with 0.5, 1, 2, and 5 wt % CdSe, respectively (Figure S4, Supporting Information File 1). Influence of the photocatalyst dosage and rhodamine B concentration The photodegradation efficiency is generally affected by the amount of catalyst used and by the
  • mg of photocatalyst. As expected, the photocatalytic degradation rates increased with the catalyst dosage, which is linked to the concentration of adsorption sites and photocatalytically active sites (k = 0.010, 0.019 and 0.034 min−1 for reactions conducted with 25, 50 and 100 mg of photocatalyst
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Published 19 Dec 2017

Localized growth of carbon nanotubes via lithographic fabrication of metallic deposits

  • Fan Tu,
  • Martin Drost,
  • Imre Szenti,
  • Janos Kiss,
  • Zoltan Kónya and
  • Hubertus Marbach

Beilstein J. Nanotechnol. 2017, 8, 2592–2605, doi:10.3762/bjnano.8.260

Graphical Abstract
  • Fe samples were transferred under ambient conditions to the CVD apparatus at the University of Szeged, Hungary. Therefore, oxidation of the Fe deposits, forming Fe2O3 and Fe3O4, is anticipated as discussed previously [32]. However, exposure to H2 for ten minutes before the CVD and simultaneous dosage
  • , Germany) [51]. Dot exposures were performed using the SEM spot mode while square structures were all fabricated with a step size of 6.2 nm. The AG process was performed by continuous precursor dosage after the EBID process. The corresponding AG time quoted in this study is the time of the subsequent
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Published 05 Dec 2017

Carbon nanomaterials sensitize prostate cancer cells to docetaxel and mitomycin C via induction of apoptosis and inhibition of proliferation

  • Kati Erdmann,
  • Jessica Ringel,
  • Silke Hampel,
  • Manfred P. Wirth and
  • Susanne Fuessel

Beilstein J. Nanotechnol. 2017, 8, 1307–1317, doi:10.3762/bjnano.8.132

Graphical Abstract
  • . Co-administration of chemotherapeutics with carbon nanomaterials could result in a reduction of the chemotherapeutic dosage and thus limit systemic side effects. Keywords: carbon nanomaterials; chemosensitization; docetaxel; mitomycin C; prostate cancer cells; Introduction According to the global
  • (Table 1), DTX or MMC alone had to be applied in concentrations of about 25 ng/mL and 2 µg/mL, respectively (Supporting Information File 1, Figure S1a,b). This corresponded to a reduction of the chemotherapeutic dosage down to a seventeenth and a seventh, respectively, in the combinatory treatments in
  • S1c,d) [28]. Consistently, the reduction of the chemotherapeutic dosage was more distinct in combinatory treatments with CNFs independent of the chemotherapeutic used. A combined application with carbon nanomaterials would also result in an improved cellular uptake of the active drug component as
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Published 23 Jun 2017

“Sticky invasion” – the physical properties of Plantago lanceolata L. seed mucilage

  • Agnieszka Kreitschitz,
  • Alexander Kovalev and
  • Stanislav N. Gorb

Beilstein J. Nanotechnol. 2016, 7, 1918–1927, doi:10.3762/bjnano.7.183

Graphical Abstract
  • features mucilage finds diverse applications in pharmacy as, e.g., tablet binders, disintegrants, emulsifiers, and suspending or thickening agent. Mucilage as polymer was also studied for the application in pharmaceutical dosage as, e.g., film coating agents, buccal films or nanoparticles [31]. In the
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Published 05 Dec 2016

Chitosan-based nanoparticles for improved anticancer efficacy and bioavailability of mifepristone

  • Huijuan Zhang,
  • Fuqiang Wu,
  • Yazhen Li,
  • Xiping Yang,
  • Jiamei Huang,
  • Tingting Lv,
  • Yingying Zhang,
  • Jianzhong Chen,
  • Haijun Chen,
  • Yu Gao,
  • Guannan Liu and
  • Lee Jia

Beilstein J. Nanotechnol. 2016, 7, 1861–1870, doi:10.3762/bjnano.7.178

Graphical Abstract
  • ]. Because the side effects of MIF are closely related with its dosage, some studies have been implemented to find the optimum dosage of MIF [7] or to develop new formulations for MIF to improve its bioavailability [8]. Chitosan (Cs) is a basic polysaccharide found in nature with good biocompatibility and
  • Care and Use Committee to reduce the suffering and use of animals. Oral administration Eight male SD rats were randomly divided into two groups (n = 4). Group 1 was given a single 30 mg/kg dose of MIF (in soybean oil solution) and Group 2 was given a single dose of MCNs equivalent to the same dosage of
  • MCNs equivalent to the same dosage of MIF. Blood samples (each 0.5 mL) were collected into heparinized tubes from the orbital venous plexus at different time points after oral administration. Pharmacokinetic parameters of different MIF formulations. Acknowledgements This work was supported by the
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Published 28 Nov 2016

Preparation of alginate–chitosan–cyclodextrin micro- and nanoparticles loaded with anti-tuberculosis compounds

  • Albert Ivancic,
  • Fliur Macaev,
  • Fatma Aksakal,
  • Veaceslav Boldescu,
  • Serghei Pogrebnoi and
  • Gheorghe Duca

Beilstein J. Nanotechnol. 2016, 7, 1208–1218, doi:10.3762/bjnano.7.112

Graphical Abstract
  • treatment of lung infections. Among others, these are the reduction of the systemic toxicity, the availability of high drug concentrations at the site of action, and the avoidance of the first-pass effect [6]. The main challenges connected to this type of formulations are problems with correct dosage
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Published 24 Aug 2016

PLGA nanoparticles as a platform for vitamin D-based cancer therapy

  • Maria J. Ramalho,
  • Joana A. Loureiro,
  • Bárbara Gomes,
  • Manuela F. Frasco,
  • Manuel A. N. Coelho and
  • M. Carmo Pereira

Beilstein J. Nanotechnol. 2015, 6, 1306–1318, doi:10.3762/bjnano.6.135

Graphical Abstract
  • activity, allowing reduced administration frequency, as well as lower drug dosage, and thus increased drug bioavailability. This work also demonstrated that encapsulation in a nanovehicle enhanced the growth inhibition effect of calcitriol in the treated human cell lines by inducing cell cycle arrest in
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Published 12 Jun 2015

Influence of gold, silver and gold–silver alloy nanoparticles on germ cell function and embryo development

  • Ulrike Taylor,
  • Daniela Tiedemann,
  • Christoph Rehbock,
  • Wilfried A. Kues,
  • Stephan Barcikowski and
  • Detlef Rath

Beilstein J. Nanotechnol. 2015, 6, 651–664, doi:10.3762/bjnano.6.66

Graphical Abstract
  • applied in extremly small sizes in conjuction with high dosages (<2 nm, 1014 NP per embryo). (iii) Concerning oocytes and embryos silver nanoparticles are considerable more toxic than gold nanoparticles, with a clear dependency on the applied dosage. A clearly defined toxic threshold is difficult to
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Published 05 Mar 2015

Functionalized polystyrene nanoparticles as a platform for studying bio–nano interactions

  • Cornelia Loos,
  • Tatiana Syrovets,
  • Anna Musyanovych,
  • Volker Mailänder,
  • Katharina Landfester,
  • G. Ulrich Nienhaus and
  • Thomas Simmet

Beilstein J. Nanotechnol. 2014, 5, 2403–2412, doi:10.3762/bjnano.5.250

Graphical Abstract
  • resistance and cannot be applied orally. Such drugs could be encapsulated within nanoparticles protecting the drug, generating a new hydrophilic surface, improving pharmacokinetics and targeting the drug to distinct cells and tissues This would enable a reduction of the drug dosage thereby improving the
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Published 15 Dec 2014

Nanobioarchitectures based on chlorophyll photopigment, artificial lipid bilayers and carbon nanotubes

  • Marcela Elisabeta Barbinta-Patrascu,
  • Stefan Marian Iordache,
  • Ana Maria Iordache,
  • Nicoleta Badea and
  • Camelia Ungureanu

Beilstein J. Nanotechnol. 2014, 5, 2316–2325, doi:10.3762/bjnano.5.240

Graphical Abstract
  • largely used as drug delivery vehicles, showing potential in targeting specific cancer cells [18] with a necessary dosage lower than conventional drugs, without harming healthy cells and significantly reduced side effects. Another interesting property of carbon nanotubes is their antioxidant activity
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Published 02 Dec 2014

Influence of surface-modified maghemite nanoparticles on in vitro survival of human stem cells

  • Michal Babič,
  • Daniel Horák,
  • Lyubov L. Lukash,
  • Tetiana A. Ruban,
  • Yurii N. Kolomiets,
  • Svitlana P. Shpylova and
  • Oksana A. Grypych

Beilstein J. Nanotechnol. 2014, 5, 1732–1737, doi:10.3762/bjnano.5.183

Graphical Abstract
  • drugs to specific types of cells in a body, in order to greatly reduce both the needed dosage and the side effects of the drug [6][7][8]. At the same time, the long-term fate of the particles and their possible cytotoxic effects on cells of the human body have to be taken into account to evaluate
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Published 08 Oct 2014

Precise quantification of silica and ceria nanoparticle uptake revealed by 3D fluorescence microscopy

  • Adriano A. Torrano and
  • Christoph Bräuchle

Beilstein J. Nanotechnol. 2014, 5, 1616–1624, doi:10.3762/bjnano.5.173

Graphical Abstract
  • nanoparticles. The flow is generated by a novel microfluidic reactor that can be combined with live-cell imaging and is able to cover the entire physiological range of shear rates [31]. Comparison to other methods Customary techniques performed for achieving the dosage of particles taken up by cells include
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Published 23 Sep 2014

Mimicking exposures to acute and lifetime concentrations of inhaled silver nanoparticles by two different in vitro approaches

  • Fabian Herzog,
  • Kateryna Loza,
  • Sandor Balog,
  • Martin J. D. Clift,
  • Matthias Epple,
  • Peter Gehr,
  • Alke Petri-Fink and
  • Barbara Rothen-Rutishauser

Beilstein J. Nanotechnol. 2014, 5, 1357–1370, doi:10.3762/bjnano.5.149

Graphical Abstract
  • in epon [71]. From the embedded cells, ultrathin sections were cut parallel to the vertical axis of the inserts, mounted on copper grids and stained with uranyl acetate. Imaging was done with a Philips CM12 TEM (FEI Co Philips Electron Optics). Estimation of NP dosage in dispersion over time The in
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Published 26 Aug 2014

Electron-beam induced deposition and autocatalytic decomposition of Co(CO)3NO

  • Florian Vollnhals,
  • Martin Drost,
  • Fan Tu,
  • Esther Carrasco,
  • Andreas Späth,
  • Rainer H. Fink,
  • Hans-Peter Steinrück and
  • Hubertus Marbach

Beilstein J. Nanotechnol. 2014, 5, 1175–1185, doi:10.3762/bjnano.5.129

Graphical Abstract
  • brightness of the deposits and the cluster growth mode are in line with the autocatalytic growth of EBID deposits upon dosage of additional Co(CO)3NO. The samples were further characterized at the PolLux soft X-ray STXM beamline [28] at the Swiss Light Source using a zone plate with a nominal resolution of
  • autocatalytic decomposition upon further precursor dosage. The two precursors show very different growth characteristics under the applied reaction conditions. Structure fabrication by using Co(CO)3NO is strongly affected by the applied electron dose in the EBID step and subsequent autocatalytic growth time
  • deposits at an enlarged photon energy scale, along with the spectrum of a Co layer produced by PVD as reference (grey). Evaluation of the X-ray absorption data for the growth of Co-containing deposits by EBID plus autocatalytic growth upon Co(CO)3NO dosage. a) Optical density (left vertical axis) and
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Published 30 Jul 2014

Antimicrobial properties of CuO nanorods and multi-armed nanoparticles against B. anthracis vegetative cells and endospores

  • Pratibha Pandey,
  • Merwyn S. Packiyaraj,
  • Himangini Nigam,
  • Gauri S. Agarwal,
  • Beer Singh and
  • Manoj K. Patra

Beilstein J. Nanotechnol. 2014, 5, 789–800, doi:10.3762/bjnano.5.91

Graphical Abstract
  • deadly B. anthracis spores and vegetative cells. However the limited work still underscores the potential of a nanomaterial-mediated decontamination of BW agents. Prasad et al. [13] have reported some degree of deactivation of B. anthracis cells by UV light assisted TiO2 nanoparticles at a dosage ranging
  • first 30 min of exposure to CuO nanoparticles (P5). Interestingly even 0.5 mg/mL dose of the NPs was capable of killing over 99% of B. anthracis vegetative cells. Afterward, up to 4 h the rate of decrease was not that high, even for higher dosage up to 6 mg/mL P5 NPs. In terms of absolute data after
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Published 05 Jun 2014

Spontaneous dissociation of Co2(CO)8 and autocatalytic growth of Co on SiO2: A combined experimental and theoretical investigation

  • Kaliappan Muthukumar,
  • Harald O. Jeschke,
  • Roser Valentí,
  • Evgeniya Begun,
  • Johannes Schwenk,
  • Fabrizio Porrati and
  • Michael Huth

Beilstein J. Nanotechnol. 2012, 3, 546–555, doi:10.3762/bjnano.3.63

Graphical Abstract
  • injection system for 30 min, causing a pressure increase to 3 × 10−5 mbar, which dropped within ten minutes to about 6 × 10−6 mbar. The gas injection system employs a stainless-steel precursor capsule with a fine-dosage valve. The precursor temperature was set by the ambient conditions to 27 °C. From the
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Published 25 Jul 2012

The morphology of silver nanoparticles prepared by enzyme-induced reduction

  • Henrik Schneidewind,
  • Thomas Schüler,
  • Katharina K. Strelau,
  • Karina Weber,
  • Dana Cialla,
  • Marco Diegel,
  • Roland Mattheis,
  • Andreas Berger,
  • Robert Möller and
  • Jürgen Popp

Beilstein J. Nanotechnol. 2012, 3, 404–414, doi:10.3762/bjnano.3.47

Graphical Abstract
  • the high-energy yield for the simulated film curve; and (3) the maximum height hmax of the silver nanoparticles by comparing the low-energy tail of silver with that of the homogenous silver film. In order to study the surface density and the total particle number (i.e., the dosage) of silver in the
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Published 18 May 2012
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