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Search for "biomedical" in Full Text gives 355 result(s) in Beilstein Journal of Nanotechnology. Showing first 200.

Towards a quantitative theory for transmission X-ray microscopy

  • James G. McNally,
  • Christoph Pratsch,
  • Stephan Werner,
  • Stefan Rehbein,
  • Andrew Gibbs,
  • Jihao Wang,
  • Thomas Lunkenbein,
  • Peter Guttmann and
  • Gerd Schneider

Beilstein J. Nanotechnol. 2025, 16, 1113–1128, doi:10.3762/bjnano.16.82

Graphical Abstract
  • ; transmission X-ray microscope; Introduction Transmission X-ray microscopes (TXMs) operating in the soft and tender X-ray energy range are valuable tools for structural analysis in both biomedical and materials science research [1][2][3][4]. These microscopes yield images at a lateral resolution approaching 25
  • nm, from which quantitative data are often extracted. For example, in materials science applications, nanoscale spectromicroscopy [5][6][7][8] is used to examine a sample around its absorption edges, which provides insights into its electronic structure. In biomedical applications [9][10][11][12
  • model. This will then enable more quantitatively accurate measurements in both spectromicroscopy and biomedical imaging. Experimental The measured data [35] were obtained by allowing both 60 nm gold nanospheres and 270 nm gold shells from a colloidal gold suspension to dry onto holey carbon-coated gold
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Published 15 Jul 2025

Fabrication of metal complex phthalocyanine and porphyrin nanoparticle aqueous colloids by pulsed laser fragmentation in liquid and their potential application to a photosensitizer for photodynamic therapy

  • Taisei Himeda,
  • Risako Kunitomi,
  • Ryosuke Nabeya,
  • Tamotsu Zako and
  • Tsuyoshi Asahi

Beilstein J. Nanotechnol. 2025, 16, 1088–1096, doi:10.3762/bjnano.16.80

Graphical Abstract
  • biological optical window (wavelengths from 650 to 1000 nm) and have recently attracted attention for applications in biomedical research such as photoacoustic imaging of tissues and PDT of tumors [2][3]. Porphyrins and Pcs are hydrophobic hydrocarbons that are insoluble in water. Hence, polymer composite
  • polypropylene oxide (PPO) arranged in a triblock structure. Here, the stability in phosphate-buffered saline (PBS, pH 7.2), which is used widely in pharmacology and biomedical experiments, was examined. We evaluated the phototoxicity of the fabricated nanoparticle colloids in vitro against PC12 cells (a cell
  • useful as a potential photosensitizer for PDT treatments in biomedical applications. Experimental Materials Cobalt(II) phthalocyanine (CoPc, 97%), nickel(II) phthalocyanine (NiPc, 85%), platinum octaethylporphyrin (PtOEP, 98%), and Pluronic® F-127 were purchased from Sigma-Aldrich. Chloroaluminum
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Published 11 Jul 2025

Piezoelectricity of hexagonal boron nitrides improves bone tissue generation as tested on osteoblasts

  • Sevin Adiguzel,
  • Nilay Cicek,
  • Zehra Cobandede,
  • Feray B. Misirlioglu,
  • Hulya Yilmaz and
  • Mustafa Culha

Beilstein J. Nanotechnol. 2025, 16, 1068–1081, doi:10.3762/bjnano.16.78

Graphical Abstract
  • stimulate electrically excitable cells without requiring an external power source, making them highly attractive for biomedical applications such as treating cardiac arrhythmias and promoting bone regeneration [17][18]. Mechanical stimulation, notably ultrasound (US), can induce a piezoelectric response in
  • , making them particularly attractive for biomedical applications. [21][22]. Barium titanate (BaTiO3) is one of the most well-known piezoelectric nanomaterials (NMs), characterized by a cubic structure with four polymorphs which change depending on the temperature and a high dielectric constant. All its
  • properties due to its noncentrosymmetric crystal structure, making it a promising material for biomedical applications such as bone regeneration, where it can convert mechanical stimuli into bioelectrical signals. Additionally, the biocompatibility and ability of hBN to be integrated into composite scaffolds
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Published 07 Jul 2025

Soft materials nanoarchitectonics: liquid crystals, polymers, gels, biomaterials, and others

  • Katsuhiko Ariga

Beilstein J. Nanotechnol. 2025, 16, 1025–1067, doi:10.3762/bjnano.16.77

Graphical Abstract
  • as biomedical applications [15][16][17][18][19][20], but also extends to functional material systems that address issues such as energy [21][22][23][24][25] and environment [26][27][28][29][30]. The creation of such soft functional materials has been fostered alongside the advancement of science
  • release of protein biopharmaceuticals in response to antibodies. It is anticipated that these hydrogels will prove useful in a number of biomedical applications, including the three-dimensional controlled release of drugs and proteins, the construction of hierarchical organoids, and the development of
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Published 04 Jul 2025

Multifunctional properties of bio-poly(butylene succinate) reinforced with multiwalled carbon nanotubes

  • Volodymyr Krasinskyi,
  • Krzysztof Bajer,
  • Ludmila Dulebova,
  • Nickolas Polychronopoulos,
  • Oksana Krasinska and
  • Daniel Kaczor

Beilstein J. Nanotechnol. 2025, 16, 1014–1024, doi:10.3762/bjnano.16.76

Graphical Abstract
  • of MWCNTs to tailor the properties of BioPBS for specific applications, such as in the packaging, automotive, and biomedical industries, where both biodegradability and enhanced material performance are desirable. Keywords: melt compounding; multiwalled carbon nanotubes; poly(butylene succinate
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Published 03 Jul 2025

A calix[4]arene-based supramolecular nanoassembly targeting cancer cells and triggering the release of nitric oxide with green light

  • Cristina Parisi,
  • Loredana Ferreri,
  • Tassia J. Martins,
  • Francesca Laneri,
  • Samantha Sollima,
  • Antonina Azzolina,
  • Antonella Cusimano,
  • Nicola D’Antona,
  • Grazia M. L. Consoli and
  • Salvatore Sortino

Beilstein J. Nanotechnol. 2025, 16, 1003–1013, doi:10.3762/bjnano.16.75

Graphical Abstract
  • , C.N.R., I-95126 Catania, Italy Institute for Biomedical Research and Innovation, National Research Council (CNR), I-90146 Palermo, Italy 10.3762/bjnano.16.75 Abstract We have designed and synthesized a novel calix[4]arene derivative bearing four choline appendages as recognition targeting ligands and
  • immunogenicity and paving the way for a variety of applications in the biomedical field [1][6][7][8][9]. Due to their amphiphilic character, calix[n]arene derivatives can self-assemble in water medium, leading to nanoaggregates exhibiting much better hosting performances than the single monomers [10]. Aggregates
  • poorly active unconventional photoactivatable drug molecules [12][13][14] as well as efficient cages to inhibit undesired photodegradation of photosensitive conventional drugs [15]. Nitric oxide (NO) is one of the most extensively studied molecules in the fascinating realm of biomedical sciences. This
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Published 03 Jul 2025

Structural and magnetic properties of microwave-synthesized reduced graphene oxide/VO2/Fe2O3 nanocomposite

  • Sumanta Sahoo,
  • Ankur Sood and
  • Sung Soo Han

Beilstein J. Nanotechnol. 2025, 16, 921–932, doi:10.3762/bjnano.16.70

Graphical Abstract
  • Fe2O3 nanoparticles and VO2 nanorods on the 2D rGO surface. Notably, the ternary composite displayed good magnetic properties for its potential biomedical applications. Overall, this work explores an efficient and cost-effective synthetic approach for developing graphene-based magnetic nanocomposites
  • , including their derivatives, are broadly explored for miscellaneous applications, such as energy storage/conversion, EMI shielding, biosensing, optoelectronics, robotics, flexible electronics, paint industries, textile industries, biomedical devices [5][6][7]. To be specific, the innovation of graphene
  • , the approach was also able to convert V2O5 to form VO2 and synthesize Fe2O3 from ferrocene. The structure and properties of the NC were examined through various characterization techniques. Lastly, the magnetic properties of Fe-containing ternary NCs were also evaluated for their possible biomedical
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Published 20 Jun 2025

Synthesis and magnetic transitions of rare-earth-free Fe–Mn–Ni–Si-based compositionally complex alloys at bulk and nanoscale

  • Shabbir Tahir,
  • Tatiana Smoliarova,
  • Carlos Doñate-Buendía,
  • Michael Farle,
  • Natalia Shkodich and
  • Bilal Gökce

Beilstein J. Nanotechnol. 2025, 16, 823–836, doi:10.3762/bjnano.16.62

Graphical Abstract
  • ], wear resistant coatings [29], environmental [30], biomedical [31], magnetic [32] and electronic [33] technologies. In magnetic NPs, a key feature is the superparamagnetic blocked-to-superparamagnetic fluctuating transition, which occurs at a characteristic blocking temperature (TB). Below TB, NPs
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Published 05 Jun 2025

Supramolecular hydration structure of graphene-based hydrogels: density functional theory, green chemistry and interface application

  • Hon Nhien Le,
  • Duy Khanh Nguyen,
  • Minh Triet Dang,
  • Huyen Trinh Nguyen,
  • Thi Bang Tam Dao,
  • Trung Do Nguyen,
  • Chi Nhan Ha Thuc and
  • Van Hieu Le

Beilstein J. Nanotechnol. 2025, 16, 806–822, doi:10.3762/bjnano.16.61

Graphical Abstract
  • Zn(OH)2 constituent). ZH nanoparticles and GO nanosheets in the GO-SG-ZH hydrogel are antibacterial and antibiofilm agents with low toxicity for food packaging and biomedical applications [56][57]. The main antibacterial mechanism of GO nanosheets is cell membrane damage caused by direct contact of
  • biomedical applications thanks to its antibiofilm, safety, and biodegradability properties. Stability of graphene oxide–nanosilica–zinc hydroxide coatings on polylactide films in aqueous environments SG/PLA and GO-SG-ZH/PLA films were immersed in an environment simulating aqueous food for one month. The
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Published 04 Jun 2025

Colloidal few layered graphene–tannic acid preserves the biocompatibility of periodontal ligament cells

  • Teissir Ben Ammar,
  • Naji Kharouf,
  • Dominique Vautier,
  • Housseinou Ba,
  • Nivedita Sudheer,
  • Philippe Lavalle and
  • Vincent Ball

Beilstein J. Nanotechnol. 2025, 16, 664–677, doi:10.3762/bjnano.16.51

Graphical Abstract
  • satisfactory biocompatibility, FLG–TA potentially offers new insights as a novel biomaterial for dental applications. The addition of TA to the FLG surface enhances both physicochemical and biological properties. This advantageous combination expands the potential uses of the biocomposite across biomedical
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Published 20 May 2025

Nanoscale capacitance spectroscopy based on multifrequency electrostatic force microscopy

  • Pascal N. Rohrbeck,
  • Lukas D. Cavar,
  • Franjo Weber,
  • Peter G. Reichel,
  • Mara Niebling and
  • Stefan A. L. Weber

Beilstein J. Nanotechnol. 2025, 16, 637–651, doi:10.3762/bjnano.16.49

Graphical Abstract
  • ; quantitative force spectroscopy; scanning capacitance force microscopy; Introduction Technological progress in fields including electronics, energy storage, photonics, and biomedical devices would not have been possible without the development of new materials. Progress in these areas requires a detailed
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Published 08 May 2025

Polyurethane/silk fibroin-based electrospun membranes for wound healing and skin substitute applications

  • Iqra Zainab,
  • Zohra Naseem,
  • Syeda Rubab Batool,
  • Muhammad Waqas,
  • Ahsan Nazir and
  • Muhammad Anwaar Nazeer

Beilstein J. Nanotechnol. 2025, 16, 591–612, doi:10.3762/bjnano.16.46

Graphical Abstract
  • 37610, Pakistan 10.3762/bjnano.16.46 Abstract The importance of electrospun membranes for biomedical applications has increased, especially when it comes to skin regeneration and wound healing. This review presents the production and applications of electrospun membranes based on polyurethane (PU) and
  • silk fibroin (SF) and highlights their benefits as a skin substitute. This review also highlights the electrospinning technique used to prepare nanofibers for these biomedical applications. Silk, well-known for its excellent biocompatibility, biodegradability, structural properties, and low immunogenic
  • response, is extensively investigated by addressing its molecular structure, composition, and medical uses. PU is a candidate for potential biomedical applications because of its strength, flexibility, biocompatibility, cell-adhesive properties, and high resistance to biodegradation. PU combined with silk
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Published 24 Apr 2025

Nanomaterials in targeting amyloid-β oligomers: current advances and future directions for Alzheimer's disease diagnosis and therapy

  • Shiwani Randhawa,
  • Trilok Chand Saini,
  • Manik Bathla,
  • Rahul Bhardwaj,
  • Rubina Dhiman and
  • Amitabha Acharya

Beilstein J. Nanotechnol. 2025, 16, 561–580, doi:10.3762/bjnano.16.44

Graphical Abstract
  • physicochemical properties, diverse structural forms, and potential applications in combating NDs. The unique characteristics of CNMs, including their hydrophobic surfaces and variable dimensions, enable them to interact effectively with biomolecules, making them valuable tools in biomedical research and
  • valuable candidates for various biomedical applications such as diagnosis, therapeutics, and drug delivery. The efficacy of these NPs is closely linked to their pharmacokinetic properties. The biodistribution, safety profile, and clearance mechanism of NPs plays a critical role in the clinical application
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Published 22 Apr 2025

Functionalized gold nanoflowers on carbon screen-printed electrodes: an electrochemical platform for biosensing hemagglutinin protein of influenza A H1N1 virus

  • Carlos Enrique Torres-Méndez,
  • Sharmilee Nandi,
  • Klara Martinovic,
  • Patrizia Kühne,
  • Yifan Liu,
  • Sam Taylor,
  • Maria Lysandrou,
  • Maria Ines Berrojo Romeyro Mascarenhas,
  • Viktoria Langwallner,
  • Javier Enrique Sebastián Alonso,
  • Ivana Jovanovic,
  • Maike Lüftner,
  • Georgia-Vasiliki Gkountana,
  • David Bern,
  • Abdul-Raouf Atif,
  • Ehsan Manouchehri Doulabi,
  • Gemma Mestres and
  • Masood Kamali-Moghaddam

Beilstein J. Nanotechnol. 2025, 16, 540–550, doi:10.3762/bjnano.16.42

Graphical Abstract
  • Manouchehri Doulabi Gemma Mestres Masood Kamali-Moghaddam Division of Biomedical Engineering, Department of Materials Science and Engineering, Uppsala University, Uppsala, Sweden Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden 10.3762/bjnano
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Published 16 Apr 2025

Electron beam-based direct writing of nanostructures using a palladium β-ketoesterate complex

  • Chinmai Sai Jureddy,
  • Krzysztof Maćkosz,
  • Aleksandra Butrymowicz-Kubiak,
  • Iwona B. Szymańska,
  • Patrik Hoffmann and
  • Ivo Utke

Beilstein J. Nanotechnol. 2025, 16, 530–539, doi:10.3762/bjnano.16.41

Graphical Abstract
  • applications [32][33][34], palladium is an important metal as it is the optimal material to make metallic contacts with CNTs [35]. Palladium nanoparticles are also being explored for biomedical applications and sensors [36]. Therefore, Pd nanoprinting via FEBID could emerge as a key technique for creating
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Published 15 Apr 2025

Synthetic-polymer-assisted antisense oligonucleotide delivery: targeted approaches for precision disease treatment

  • Ana Cubillo Alvarez,
  • Dylan Maguire and
  • Ruairí P. Brannigan

Beilstein J. Nanotechnol. 2025, 16, 435–463, doi:10.3762/bjnano.16.34

Graphical Abstract
  • its characteristic amphipathic guanidinium group, PLR has been frequently used in biomedical applications, particularly as a carrier for nucleic acid delivery [91]. Moreover, its strong cationic nature allows it to effectively bind to negatively charged molecules, facilitating cellular uptake through
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Published 27 Mar 2025

Size control of nanoparticles synthesized by pulsed laser ablation in liquids using donut-shaped beams

  • Abdel Rahman Altakroury,
  • Oleksandr Gatsa,
  • Farbod Riahi,
  • Zongwen Fu,
  • Miroslava Flimelová,
  • Andrei Samokhvalov,
  • Stephan Barcikowski,
  • Carlos Doñate-Buendía,
  • Alexander V. Bulgakov and
  • Bilal Gökce

Beilstein J. Nanotechnol. 2025, 16, 407–417, doi:10.3762/bjnano.16.31

Graphical Abstract
  • the size, requiring a monodisperse or at least monomodal size distribution. As an example, gold NPs with a narrow particle size distribution achieve a higher detection sensitivity in sensing applications [9]. Besides, NP size is critical for biomedical applications, where deviations from the optimum
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Published 25 Mar 2025

Development of a mucoadhesive drug delivery system and its interaction with gastric cells

  • Ahmet Baki Sahin,
  • Serdar Karakurt and
  • Deniz Sezlev Bilecen

Beilstein J. Nanotechnol. 2025, 16, 371–384, doi:10.3762/bjnano.16.28

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  • concluded that EudAlg nanoparticles do not significantly affect the viability of AGS cell (Figure 4A). Internalization of nanoparticles When nanoparticles are designed for biomedical applications, two important properties to be considered are toxicity and cellular uptake. The cellular uptake of
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Published 13 Mar 2025

Pulsed laser in liquid grafting of gold nanoparticle–carbon support composites

  • Madeleine K. Wilsey,
  • Teona Taseska,
  • Qishen Lyu,
  • Connor P. Cox and
  • Astrid M. Müller

Beilstein J. Nanotechnol. 2025, 16, 349–361, doi:10.3762/bjnano.16.26

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  • , catalysis, sensing, and biomedical fields. Conclusion Pulsed laser grafting of gold nanoparticle–carbon fiber paper composites presents a significant advancement in electrode design for electrocatalytic applications. Our novel one-step aqueous pulsed laser grafting process enables the fabrication of
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Published 07 Mar 2025

Graphene oxide–chloroquine conjugate induces DNA damage in A549 lung cancer cells through autophagy modulation

  • Braham Dutt Arya,
  • Sandeep Mittal,
  • Prachi Joshi,
  • Alok Kumar Pandey,
  • Jaime E. Ramirez-Vick,
  • Govind Gupta and
  • Surinder P. Singh

Beilstein J. Nanotechnol. 2025, 16, 316–332, doi:10.3762/bjnano.16.24

Graphical Abstract
  • Education, Shiksha Sadan, Sector-5, Panchkula-134114, India CSIR-Indian Institute of Toxicology Research (CSIR-IITR), 31, Mahatma Gandhi Marg, Lucknow-226001, India Department of Biomedical, Industrial & Human Factors Engineering, Wright State University, Dayton, Ohio 45435, United States 10.3762/bjnano
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Published 03 Mar 2025

Enhancing mechanical properties of chitosan/PVA electrospun nanofibers: a comprehensive review

  • Nur Areisman Mohd Salleh,
  • Amalina Muhammad Afifi,
  • Fathiah Mohamed Zuki and
  • Hanna Sofia SalehHudin

Beilstein J. Nanotechnol. 2025, 16, 286–307, doi:10.3762/bjnano.16.22

Graphical Abstract
  • Department of Chemical Engineering, Faculty of Engineering, University of Malaya, 50603 Kuala Lumpur, Malaysia 10.3762/bjnano.16.22 Abstract This review examines strategies to enhance the mechanical properties of chitosan/polyvinyl alcohol (PVA) electrospun nanofibers, recognized for their biomedical and
  • evaluate mechanical properties and provides a comparative analysis of different enhancement approaches. Applications in biomedical and industrial contexts are explored, showcasing the versatility and innovation potential of these nanofibers. Finally, current challenges are addressed, and future research
  • sensitive compounds [3]. Electrospun nanofibers exhibit a large surface area, high porosity, and small pore size, making them useful for a wide range of applications, as shown in Figure 1. Chitosan/polyvinyl alcohol (PVA) electrospun nanofibers have many applications, including water treatment, biomedical
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Published 26 Feb 2025

Nanocarriers and macrophage interaction: from a potential hurdle to an alternative therapeutic strategy

  • Naths Grazia Sukubo,
  • Paolo Bigini and
  • Annalisa Morelli

Beilstein J. Nanotechnol. 2025, 16, 97–118, doi:10.3762/bjnano.16.10

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  • transport across membranes, and extend circulation times. These advantages could reduce the negative effects of off-target drug accumulation and improve the release to the disease sites compared to current delivery systems [6]. Despite the expected applications in the biomedical field, the journey of NPs
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Published 31 Jan 2025

Characterization of ZnO nanoparticles synthesized using probiotic Lactiplantibacillus plantarum GP258

  • Prashantkumar Siddappa Chakra,
  • Aishwarya Banakar,
  • Shriram Narayan Puranik,
  • Vishwas Kaveeshwar,
  • C. R. Ravikumar and
  • Devaraja Gayathri

Beilstein J. Nanotechnol. 2025, 16, 78–89, doi:10.3762/bjnano.16.8

Graphical Abstract
  • biomedical applications. This work reports on the green synthesis of ZnO NPs employing lactic acid bacteria (LAB) as capping and reducing agents to produce biocompatible NPs for use in pharmaceutical and biological applications [3][4][5]. LAB are Gram-positive, catalase-negative, and non-pathogenic bacteria
  • , suggesting their potential utility in environmental contexts and as biomedical coatings. Conclusion This work effectively proved the use of native lactic acid bacteria as capping and reducing agents in the green synthesis of ZnO NPs. The NPs exhibited potential structural, optical, and biological qualities
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Published 30 Jan 2025

Theoretical study of the electronic and optical properties of a composite formed by the zeolite NaA and a magnetite cluster

  • Joel Antúnez-García,
  • Roberto Núñez-González,
  • Vitalii Petranovskii,
  • H’Linh Hmok,
  • Armando Reyes-Serrato,
  • Fabian N. Murrieta-Rico,
  • Mufei Xiao and
  • Jonathan Zamora

Beilstein J. Nanotechnol. 2025, 16, 44–53, doi:10.3762/bjnano.16.5

Graphical Abstract
  • ], heavy metal removal [11][12], sensor technologies [13][14][15][16], and biomedical applications [17]. Nanoscale materials represent a thriving field of research with a wide range of potential applications. Today, it is generally recognized that properties like hardness, reactivity, toxicity, and optical
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Published 17 Jan 2025

Fabrication of hafnium-based nanoparticles and nanostructures using picosecond laser ablation

  • Abhishek Das,
  • Mangababu Akkanaboina,
  • Jagannath Rathod,
  • R. Sai Prasad Goud,
  • Kanaka Ravi Kumar,
  • Raghu C. Reddy,
  • Ratheesh Ravendran,
  • Katia Vutova,
  • S. V. S. Nageswara Rao and
  • Venugopal Rao Soma

Beilstein J. Nanotechnol. 2024, 15, 1639–1653, doi:10.3762/bjnano.15.129

Graphical Abstract
  • them to be used in high-temperature alloys and ceramics. Hf compounds are widely used in microelectronics because of their high dielectricity values [2]. In recent years, NPs derived from Hf have gained significant interest in biomedical fields because of their superior optical and thermal properties
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Published 18 Dec 2024
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