Photothermal ablation of murine melanomas by Fe₃O₄ nanoparticle clusters

• Xue Wang,
• Lili Xuan and
• Ying Pan

Beilstein J. Nanotechnol. 2022, 13, 255–264, doi:10.3762/bjnano.13.20

• 59.4 emu/g (Figure 1c) and stronger absorption intensities at the NIR wavelength of 808 nm than individual nanoparticles [17]. In addition, the dynamic light scattering (DLS) analysis of NPCs suspended in aqueous culture medium reflected good dispersion (Figure 1d). The colloidal stability of our

• morphology of the as-synthesized nanoparticle clusters was characterized with a JEOL JEM-2100 transmission electron microscopy (TEM). Dynamic light scattering (DLS) The synthesized Fe3O4 NPCs were diluted in RPMI 1640 medium to a final concentration of 0.25 mg/mL. The particle size distribution was

A photonic crystal material for the online detection of nonpolar hydrocarbon vapors

• Evgenii S. Bolshakov,
• Aleksander V. Ivanov,
• Andrei A. Kozlov,
• Anton S. Aksenov,
• Elena V. Isanbaeva,
• Sergei E. Kushnir,
• Aleksei D. Yapryntsev,
• Aleksander E. Baranchikov and
• Yury A. Zolotov

Beilstein J. Nanotechnol. 2022, 13, 127–136, doi:10.3762/bjnano.13.9

• . Black lines show the linear correspondence of the experimental data. (a) Photo of the sensor and (b) electron microscopy image of a CCA of polystyrene particles without a PDMS layer on a glass substrate (effective particle size = 201 nm). The data obtained with dynamic light scattering slightly

• overestimates the diameter in comparison with the data obtained from microphotographs. This may be related to the specificity of the dynamic light scattering (DLS) method (hydrodynamic diameter measurement). A mechanism of detecting hydrocarbons with a sensor based on a 3D PhC: (a, b) swelling of colloidal

Bacterial safety study of the production process of hemoglobin-based oxygen carriers

• Axel Steffen,
• Yu Xiong,
• Radostina Georgieva,
• Ulrich Kalus and
• Hans Bäumler

Beilstein J. Nanotechnol. 2022, 13, 114–126, doi:10.3762/bjnano.13.8

• CCD method produces nearly uniform, peanut-shaped particles. The size distribution determined by dynamic light scattering (DLS) was 759 ± 25 nm. Confocal laser scanning microscopy (CLSM) images confirmed this size range (Figure 1C). Scanning electron microscopy (SEM) images of particles produced with

Theranostic potential of self-luminescent branched polyethyleneimine-coated superparamagnetic iron oxide nanoparticles

• Rouhollah Khodadust,
• Ozlem Unal and
• Havva Yagci Acar

Beilstein J. Nanotechnol. 2022, 13, 82–95, doi:10.3762/bjnano.13.6

• particles used for pGFP transfection. Supporting Information Supporting Information File 72: Supporting Information contains dynamic light scattering (DLS), photoluminescence spectra, and zeta potential analysis of SPION@bPEI, SPION@bPEI/pDNA, SPION@bPEI-Erb, SPION @bPEI-Erb/pDNA, and SPION@bPEI-Erb/pDNA

Biocompatibility and cytotoxicity in vitro of surface-functionalized drug-loaded spinel ferrite nanoparticles

• Sadaf Mushtaq,
• Khuram Shahzad,
• Tariq Saeed,
• Anwar Ul-Hamid,
• Bilal Haider Abbasi,
• Nafees Ahmad,
• Waqas Khalid,
• Muhammad Atif,
• Zulqurnain Ali and
• Rashda Abbasi

Beilstein J. Nanotechnol. 2021, 12, 1339–1364, doi:10.3762/bjnano.12.99

• electrophoresis. All samples moved towards the positive potential due to the negatively charged PMA coating (Figure 2d). The colloidal stability (i.e., hydrodynamic size, surface charge, and polydispersity index, PDI) of NPs was assessed using dynamic light scattering (DLS). All NPs (PMA-coated, and drug-attached

pH-driven enhancement of anti-tubercular drug loading on iron oxide nanoparticles for drug delivery in macrophages

• Karishma Berta Cotta,
• Sarika Mehra and
• Rajdip Bandyopadhyaya

Beilstein J. Nanotechnol. 2021, 12, 1127–1139, doi:10.3762/bjnano.12.84

• Cell, USA). NOR@IONP synthesis, at each of the respective pH, were performed with 3 distinct replicates. Nanoparticle characterization The hydrodynamic diameter of nanoparticles was determined after re-dispersing in milli-Q water and loading the sample in a cuvette for dynamic light scattering (DLS

• nanoparticles. (a) Dynamic light scattering plot of number (%) v/s size (nm) of the nanoparticles in solution at the end of synthesis (n = 3). (b) Transmission electron microscopy image with a 50 nm scale bar. (c) X-ray diffraction plot indicating the Bragg’s 2θ diffraction angles identical to peaks observed

• for crystalline iron oxide. (d) FTIR spectrum of transmittance v/s wavenumber, depicting major functional groups of iron oxide and NOR. Characterization of NOR@IONPpH10 nanoparticles. (a) Dynamic light scattering plot of number (%) v/s size (nm) of the nanoparticles in solution at the completion of

Fate and transformation of silver nanoparticles in different biological conditions

• Barbara Pem,
• Marija Ćurlin,
• Darija Domazet Jurašin,
• Valerije Vrček,
• Rinea Barbir,
• Vedran Micek,
• Raluca M. Fratila,
• Jesus M. de la Fuente and
• Ivana Vinković Vrček

Beilstein J. Nanotechnol. 2021, 12, 665–679, doi:10.3762/bjnano.12.53

• biological fluids, obtained from animal experiments. A multimethod approach was used to examine their behaviour and transformation under experimental conditions relevant for in vivo settings by performing dynamic light scattering (DLS), electrophoretic light scattering (ELS), graphite furnace atomic

The preparation temperature influences the physicochemical nature and activity of nanoceria

• Robert A. Yokel,
• Wendel Wohlleben,
• Johannes Georg Keller,
• Matthew L. Hancock,
• Jason M. Unrine,
• D. Allan Butterfield and
• Eric A. Grulke

Beilstein J. Nanotechnol. 2021, 12, 525–540, doi:10.3762/bjnano.12.43

• hydrodynamic diameter (Smoluchowski's approximation) of the as-prepared- (as-loaded) and the partially dissolved nanoceria was determined by dynamic light scattering (DLS) using a Brookhaven 90Plus Particle Size Analyzer. The zeta potential (0.5 mg/mL) from pH 0.5 to 13, adjusted with nitric acid and sodium

A review on nanostructured silver as a basic ingredient in medicine: physicochemical parameters and characterization

• Gabriel M. Misirli,
• Kishore Sridharan and
• Shirley M. P. Abrantes

Beilstein J. Nanotechnol. 2021, 12, 440–461, doi:10.3762/bjnano.12.36

• , UV–vis spectroscopy, inductively coupled plasma optical emission spectrometry (ICP-OES), dynamic light scattering (DLS), among other techniques [33]. The basic principles of the techniques mentioned here are detailed in the following sections. Each AgNPs is unique, depending on its size, state of

• sample stored at 4 °C leading to an overlap, which indicates size and shape stability of the nanoparticles [48]. Dynamic light scattering: Historically, the first approaches to describe interactions between light and nanostructures were published in the early 20th century. Currently, the most popular

Characterization, bio-uptake and toxicity of polymer-coated silver nanoparticles and their interaction with human peripheral blood mononuclear cells

• Sahar Pourhoseini,
• Reilly T. Enos,
• Angela E. Murphy,
• Bo Cai and
• Jamie R. Lead

Beilstein J. Nanotechnol. 2021, 12, 282–294, doi:10.3762/bjnano.12.23

• pristine AgNPs, including dynamic light scattering (DLS), UV–vis spectroscopy (UV–vis), transmission electron microscopy (TEM), and inductively coupled plasma mass spectrometry (ICP-MS). DLS gave a Z-average hydrodynamic size of 33.7 ± 0.7 nm (mean ± standard deviation) and a PDI (polydispersity index) of

Differences in surface chemistry of iron oxide nanoparticles result in different routes of internalization

• Barbora Svitkova,
• Vlasta Zavisova,
• Veronika Nemethova,
• Martina Koneracka,
• Miroslava Kretova,
• Filip Razga,
• Monika Ursinyova and
• Alena Gabelova

Beilstein J. Nanotechnol. 2021, 12, 270–281, doi:10.3762/bjnano.12.22

• characteristics of these nanoparticles in the solvent and culture medium are shown in Table 1. Dynamic light scattering (DLS) Particle size distribution and zeta potential of the surface-modified MNPs in stock solution and culture medium were determined by DLS using a Zetasizer Nano-ZS (Malvern Instruments, UK

Effect of different silica coatings on the toxicity of upconversion nanoparticles on RAW 264.7 macrophage cells

• Cynthia Kembuan,
• Helena Oliveira and
• Christina Graf

Beilstein J. Nanotechnol. 2021, 12, 35–48, doi:10.3762/bjnano.12.3

• -aminopropyltrimethoxysilane (AHAPS), which provides the nanoparticle surface with a positive charge, increasing their interaction with the cell membrane. The particles were characterized by scanning transmission electron microscopy (STEM), dynamic light scattering (DLS), electrophoretic light scattering (ELS), and

• UCNPs, was dried on a carbon-coated copper grid (Cu 400 mesh, Quantifoil®: 100 carbon support films). The images were analyzed using the software FIJI. At least 300 particles per sample were analyzed. Dynamic light scattering and electrophoretic light scattering The DLS and ELS measurements were

• , XRD data, STEM images, ICP-OES, and cell cycle data. Acknowledgements We thank I. Pieper from the research group of Prof. Dr. Martin Kaupenjohann (Technische Universität Berlin) for the ICP-OES measurements, Prof. Dr. R. Haag (Freie Universität Berlin) for providing access to the dynamic light

PEG/PEI-functionalized single-walled carbon nanotubes as delivery carriers for doxorubicin: synthesis, characterization, and in vitro evaluation

• Shuoye Yang,
• Zhenwei Wang,
• Yahong Ping,
• Yuying Miao,
• Yongmei Xiao,
• Lingbo Qu,
• Lu Zhang,
• Yuansen Hu and
• Jinshui Wang

Beilstein J. Nanotechnol. 2020, 11, 1728–1741, doi:10.3762/bjnano.11.155

• -COOH sample is distinctly smaller than that of the raw SWCNTs, and the sample treated with H2SO4/HNO3 mixed acid solution has the most even size distribution. The particle size of CNTs modified by PEG and PEI increases slightly. It should be noted that dynamic light scattering (DLS) is mainly suitable

Electrokinetic characterization of synthetic protein nanoparticles

• Daniel F. Quevedo,
• Cody J. Lentz,
• Adriana Coll de Peña,
• Yazmin Hernandez,
• Nahal Habibi,
• Rikako Miki,
• Joerg Lahann and
• Blanca H. Lapizco-Encinas

Beilstein J. Nanotechnol. 2020, 11, 1556–1567, doi:10.3762/bjnano.11.138

• diameter of 299 ± 128 nm (Figure 1b). The particles were subsequently collected and suspended in media. After allowing the particles to equilibrate for 24 h, the average particle diameter value increased to 356 ± 190 nm according to dynamic light scattering (DLS) measurements. The size distribution curves

• the desired particles. Particles, in their dry state, were imaged using SEM for shape analysis. To determine their hydrodynamic size distribution after being hydrated, the particles were suspended in ultrapure H2O + 0.01% Tween 20, sonicated on ice, and measured with dynamic light scattering (Malvern

Transient coating of γ-Fe₂O₃ nanoparticles with glutamate for its delivery to and removal from brain nerve terminals

• Konstantin Paliienko,
• Artem Pastukhov,
• Michal Babič,
• Daniel Horák,
• Olga Vasylchenko and
• Tatiana Borisova

Beilstein J. Nanotechnol. 2020, 11, 1381–1393, doi:10.3762/bjnano.11.122

• diameter Di. The dispersity (Ð) is expressed by the ratio Dw/Dn, where Dw is the weight-average particle diameter, Dw = ΣNiDi4/ΣNiDi3. The hydrodynamic diameter Dh (z-average) and polydispersity index (PI) as measures of the distribution width were obtained by dynamic light scattering (DLS) with a

• concentrations was considered as 100% in further calculations. Analysis of the size of γ-Fe2O3 nanoparticles in different media by laser correlation spectroscopy The size of γ-Fe2O3 nanoparticles was measured by dynamic light scattering using a laser correlation spectrometer ZetaSizer-3 (Malvern Instrument, UK

• media measured using laser correlation spectroscopy Nanoparticle distribution by intensity was measured using dynamic light scattering. Peak analysis (intensity) revealed that the overall mean was 171 nm in water (Figure 6a), which is a higher value than that according to the TEM micrographs (10 nm) [21

Wet-spinning of magneto-responsive helical chitosan microfibers

• Dorothea Brüggemann,
• Johanna Michel,
• Naiana Suter,
• Matheus Grande de Aguiar and
• Michael Maas

Beilstein J. Nanotechnol. 2020, 11, 991–999, doi:10.3762/bjnano.11.83

• the IOPs were homogeneously embedded as micrometer-sized agglomerates in the chitosan matrix (Figure 3B,C). Individual IOPs had a diameter of approximately 100 nm whereas their aggregates had a diameter on the order of several micrometers. According to the dynamic light scattering results (Table S2

• IOP dispersions in 1% acetic acid using a dynamic light scattering device (ZetaSizer NanoSP, Malvern, United Kingdom). Preparation of chitosan microfibers with IOPs A coagulation bath containing absolute ethanol (VWR, Darmstadt, Germany) was prepared in a polyethylene terephthalate glycol tube (MOCAP

Identification of physicochemical properties that modulate nanoparticle aggregation in blood

• Ludovica Soddu,
• Duong N. Trinh,
• Eimear Dunne,
• Dermot Kenny,
• Giorgia Bernardini,
• Ida Kokalari,
• Arianna Marucco,
• Marco P. Monopoli and
• Ivana Fenoglio

Beilstein J. Nanotechnol. 2020, 11, 550–567, doi:10.3762/bjnano.11.44

• at room temperature. In the case of SNPs, the samples were sputter-coated with a thick gold film (≈17 nm) under argon atmosphere to improve secondary electron emission during SEM imaging. The NPs morphology was observed at an acceleration voltage of 20 kV. Dynamic light scattering (DLS) The mean

• diameter and polydispersity index (PDI) of the NPs were obtained using a Zetasizer (Nano ZS Malvern Instruments, UK) instrument based on the dynamic light scattering (DLS) technique. The measurements were performed on purified NPs by analysing 0.5 mL of the suspension in ultrapure water, placed in a square

Nanoparticles based on the zwitterionic pillar[5]arene and Ag⁺: synthesis, self-assembly and cytotoxicity in the human lung cancer cell line A549

• Dmitriy N. Shurpik,
• Denis A. Sevastyanov,
• Pavel V. Zelenikhin,
• Pavel L. Padnya,
• Vladimir G. Evtugyn,
• Yuriy N. Osin and
• Ivan I. Stoikov

Beilstein J. Nanotechnol. 2020, 11, 421–431, doi:10.3762/bjnano.11.33

• studied (Figure 1). The study of self-association of macrocycles 2–4 was carried out in water using the dynamic light scattering (DLS) method. It turned out that the decaamine 2, due to its poor solubility in water, does not form any self-associates across the entire range of concentrations studied (10−3

• out after mixing the solutions at 293 K. Dynamic light scattering (DLS) The particle size distribution formed as a result of self-association of the pillar[5]arenes 2–4 was determined at 20 °С by dynamic light scattering using a nanoparticle size analyzer (Zetasizer Nano ZS, Malvern) in quartz

Brome mosaic virus-like particles as siRNA nanocarriers for biomedical purposes

• Alfredo Nuñez-Rivera,
• Pierrick G. J. Fournier,
• Danna L. Arellano,
• Ana G. Rodriguez-Hernandez,
• Rafael Vazquez-Duhalt and
• Ruben D. Cadena-Nava

Beilstein J. Nanotechnol. 2020, 11, 372–382, doi:10.3762/bjnano.11.28

• obtained by the addition of 6 μL of 1% uranyl acetate for 1 min. The size and zeta potential of the viral nanoparticles and VLPs were determined by dynamic light scattering (DLS) using a Malvern NanoSizer. The siRNA and the capsid protein were quantified from purified BMV VLP-siAkt1 using the Quant-it

Poly(1-vinylimidazole) polyplexes as novel therapeutic gene carriers for lung cancer therapy

• Gayathri Kandasamy,
• Elena N. Danilovtseva,
• Vadim V. Annenkov and
• Uma Maheswari Krishnan

Beilstein J. Nanotechnol. 2020, 11, 354–369, doi:10.3762/bjnano.11.26

• 100, Perkin Elmer, USA). Dynamic light scattering (DLS) and zeta potential measurements: The hydrodynamic size of the PVI–siRNA polyplexes was measured on a Zetasizer Nano ZS (Malvern instruments, UK). Samples at different volume ratios containing a final siRNA concentration of 100 nM were used for

• nanoparticles in the size range of 80 to 120 nm is clearly discernible from the electron micrographs. The hydrodynamic diameter of the blank PVI nanoparticles measured using dynamic light scattering was found to be about 237 ± 34.6 nm. The zeta potential measured for the blank PVI nanoparticles in HEPES buffer

The different ways to chitosan/hyaluronic acid nanoparticles: templated vs direct complexation. Influence of particle preparation on morphology, cell uptake and silencing efficiency

• Arianna Gennari,
• Julio M. Rios de la Rosa,
• Erwin Hohn,
• Maria Pelliccia,
• Enrique Lallana,
• Roberto Donno,
• Annalisa Tirella and
• Nicola Tirelli

Beilstein J. Nanotechnol. 2019, 10, 2594–2608, doi:10.3762/bjnano.10.250

• in the template process and significant aggregation takes place during the TPP–HA exchange. The templated chitosan/HA nanoparticles therefore have a mildly larger size (measured by dynamic light scattering alone or by field flow fractionation coupled to static or dynamic light scattering), and above

Long-term stability and scale-up of noncovalently bound gold nanoparticle-siRNA suspensions

• Anna V. Epanchintseva,
• Julia E. Poletaeva,
• Dmitrii V. Pyshnyi,
• Elena I. Ryabchikova and
• Inna A. Pyshnaya

Beilstein J. Nanotechnol. 2019, 10, 2568–2578, doi:10.3762/bjnano.10.248

• siRNA duplex integrity as well as siRNA surface density. Dynamic light scattering, transmission electron microscopy, UV–vis spectroscopy, and electrophoresis were used to study the effect of scaling up the AuNP-siRNA synthesis and long term storage of its suspension on physicochemical properties of the

• stability of the AuNP-siRNA suspensions during storage by gel electrophoresis and dynamic light scattering, studied the samples by transmission electron microscopy (TEM), determined spectral characteristics of the AuNP-siRNA, and monitored the preservation of the siRNA on the AuNP surface by electrophoresis

Bombesin receptor-targeted liposomes for enhanced delivery to lung cancer cells

• Mohammad J. Akbar,
• Pâmela C. Lukasewicz Ferreira,
• Melania Giorgetti,
• Leanne Stokes and
• Christopher J. Morris

Beilstein J. Nanotechnol. 2019, 10, 2553–2562, doi:10.3762/bjnano.10.246

• formulations were prepared using the thin-film technique to yield small and monodisperse vesicles as judged by dynamic light scattering (DLS) analysis (Table 1). The colloidal properties of both liposomal formulations were highly similar in terms of size, polydispersity and zeta potential and consistent with

Small protein sequences can induce cellular uptake of complex nanohybrids

• Jan-Philip Merkl,
• Malak Safi,
• Christian Schmidtke,
• Fadi Aldeek,
• Johannes Ostermann,
• Tatiana Domitrovic,
• Sebastian Gärtner,
• John E. Johnson,
• Horst Weller and
• Hedi Mattoussi

Beilstein J. Nanotechnol. 2019, 10, 2477–2482, doi:10.3762/bjnano.10.238

• stability studies in culture media were first carried out. We found no sign of aggregation build up for at least 5 hours, as verified using dynamic light scattering measurements, where mono-modal autocorrelation function along with a single intensity vs hydrodynamic size peak (i.e., Laplace transform

pH-Controlled fluorescence switching in water-dispersed polymer brushes grafted to modified boron nitride nanotubes for cellular imaging

• Saban Kalay,
• Yurij Stetsyshyn,
• Volodymyr Donchak,
• Khrystyna Harhay,
• Ostap Lishchynskyi,
• Halyna Ohar,
• Yuriy Panchenko,
• Stanislav Voronov and
• Mustafa Çulha

Beilstein J. Nanotechnol. 2019, 10, 2428–2439, doi:10.3762/bjnano.10.233

• thermogravimetric analysis (TGA), Fourier transform infrared spectroscopy (FTIR), dynamic light scattering (DLS), ultraviolet–visible spectrophotometry (UV–vis), laser scanning confocal microscopy (LSCM) and scanning electron microscopy (SEM). The DLS results demonstrated that P(AA-co-FA)-functionalized BNNTs

• 9600 nm/min scan rate. The excitation and emission wavelength and the maximum fluorescence intensity of each peak were recorded. The concentration of BNNTs was 1 mg/mL. The pH of the suspension was adjusted by adding HCl or NaOH. Dynamic light scattering (DLS) The size distribution and zeta potential