Nonclassical dynamic modeling of nano/microparticles during nanomanipulation processes

• Moharam Habibnejad Korayem,
• Ali Asghar Farid and
• Rouzbeh Nouhi Hefzabad

Beilstein J. Nanotechnol. 2020, 11, 147–166, doi:10.3762/bjnano.11.13

• the modified couple stress theory are used to model the dynamics of cylindrical gold nanoparticles while the finite element method is utilized to solve the governing equations of motion. The results show a difference of 90% between the classical and nonclassical models in predicting the maximum

• of the classical method on polystyrene nanorods. The results for cylindrical gold nanoparticles indicate that the material length scale has a major effect on the exact positioning of cylindrical nanoparticles. Keywords: atomic force microscopy; modified couple stress theory; nanomanipulation

• used for biological nanoparticles [13]. Using MSCT for modeling AFM with a piezoelectric system was considered in another study [14]. Polyakov et al. examined the dependence of static friction and contact area on nanoparticle geometry in the manipulation of spherical silver and polyhedral gold

Molecular architectonics of DNA for functional nanoarchitectures

• Debasis Ghosh,
• Lakshmi P. Datta and
• Thimmaiah Govindaraju

Beilstein J. Nanotechnol. 2020, 11, 124–140, doi:10.3762/bjnano.11.11

• the functionalization with DNA. The crystallization of nanoparticles can be easily programed by the selection of designer DNA sequences. In fact, DNA-mediated assembly is widely used to synthesize hybrid lattices of gold nanoparticles and protein-based capsid particles [97][98]. The methylation of DNA

• of DNA, and this concept has been exploited by Trau and co-workers to analyze the different interaction patterns of methylated and nonmethylated DNA with gold nanoparticles [22]. The consistent and high methylation level of genomes makes the DNA more hydrophobic, while the distinct methylation in

Gold and silver dichroic nanocomposite in the quest for 3D printing the Lycurgus cup

• Lars Kool,
• Floris Dekker,
• Anton Bunschoten,
• Glen J. Smales,
• Brian R. Pauw,
• Aldrik H. Velders and
• Vittorio Saggiomo

Beilstein J. Nanotechnol. 2020, 11, 16–23, doi:10.3762/bjnano.11.2

• nanoparticles present in the glass. In this research we show the synthesis of dichroic silver nanoparticles and their embedding in a 3D printable nanocomposite. The addition of gold nanoparticles to the silver nanoparticle composite, gave a 3D printable nanocomposite with the same dichroism effect of the

• scientists for centuries, was discovered to be due to the presence of nanoparticles in the glass. This effect was due to two different metallic nanoparticles: silver nanoparticles (AgNP) and gold nanoparticles (AuNP). While the latters are responsible for the red plasmonic colour, the silver nanoparticles

• illumination systems, with a redder coloration when illuminated by the CRI 95 LED. Although the reflected and transmitted colours of the 3D printed AgNP nanocomposite are already similar to the original Lycurgus cup, the latter is also composed of gold nanoparticles, which render the transmitted light redder

The different ways to chitosan/hyaluronic acid nanoparticles: templated vs direct complexation. Influence of particle preparation on morphology, cell uptake and silencing efficiency

• Arianna Gennari,
• Julio M. Rios de la Rosa,
• Erwin Hohn,
• Maria Pelliccia,
• Enrique Lallana,
• Roberto Donno,
• Annalisa Tirella and
• Nicola Tirelli

Beilstein J. Nanotechnol. 2019, 10, 2594–2608, doi:10.3762/bjnano.10.250

• ., liposomes [26], amphiphilic polymers [31], and gold nanoparticles [32]. We refer the reader to the excellent review of Bushell in 2002 for an extensive physico-mathematical explanation of Dm [25]. Firstly, the AF4-DLS curves (Figure 3A, left) largely overlapped. Thus, it appears that DLS alone (Figure 1

Long-term stability and scale-up of noncovalently bound gold nanoparticle-siRNA suspensions

• Anna V. Epanchintseva,
• Julia E. Poletaeva,
• Dmitrii V. Pyshnyi,
• Elena I. Ryabchikova and
• Inna A. Pyshnaya

Beilstein J. Nanotechnol. 2019, 10, 2568–2578, doi:10.3762/bjnano.10.248

• of physicochemical characteristics and siRNA surface density for a long period. Keywords: colloidal stability; gold nanoparticles; scale-up; siRNA delivery; siRNA duplex stability; therapeutic nucleic acids; Introduction Drug delivery to cells is only one application of nanoparticles in biomedicine

• and does not alter the properties and advantages of gold nanoparticles. The stability and storage duration of the nanoconstructions is important for their use in research and technology. The important properties of the nanoconstructions may be compromised during storage because of desorption and

• comparison, we presented the electropherogram of the initial bare gold nanoparticles (Figure 1G). The density of the siRNA molecules on the AuNP surface is an indicator of the efficiency of the nucleic acid transporter: the higher the density, the less amount of the preparation can be administered, thus

Advanced hybrid nanomaterials

• Andreas Taubert,
• Fabrice Leroux,
• Pierre Rabu and
• Verónica de Zea Bermudez

Beilstein J. Nanotechnol. 2019, 10, 2563–2567, doi:10.3762/bjnano.10.247

• is simultaneously employed as a contrast agent in magnetic resonance imaging (MRI) and for local heating therapy using magnetic particle hyperthermia [33]. In vitro hyperthermia tests showed efficiency in inoculating mouse breast cancer cells. Another study reports the use of alendronate-coated gold

• nanoparticles [34]. The resulting gold–alendronate nanoplatform combines antitumor activity through drug delivery and photothermal therapy, as illustrated in vitro on the inhibition of prostate cancer cells. In the field of hybrid coordination networks, new lanthanide-based networks synthesized by a solvo

Label-free highly sensitive probe detection with novel hierarchical SERS substrates fabricated by nanoindentation and chemical reaction methods

• Jingran Zhang,
• Tianqi Jia,
• Yongda Yan,
• Li Wang,
• Peng Miao,
• Yimin Han,
• Xinming Zhang,
• Guangfeng Shi,
• Yanquan Geng,
• Zhankun Weng,
• Daniel Laipple and
• Zuobin Wang

Beilstein J. Nanotechnol. 2019, 10, 2483–2496, doi:10.3762/bjnano.10.239

• etching. For instance, Chen et al. [8] employed an electrochemical etching method to fabricate nanocube structures on a Cu30Mn70 surface by controlling the voltage. In addition, Zhang et al. [10] showed that gold nanoparticles can be fabricated by a gold etchant on a silicon surface as SERS substrates

Small protein sequences can induce cellular uptake of complex nanohybrids

• Jan-Philip Merkl,
• Malak Safi,
• Christian Schmidtke,
• Fadi Aldeek,
• Johannes Ostermann,
• Tatiana Domitrovic,
• Sebastian Gärtner,
• John E. Johnson,
• Horst Weller and
• Hedi Mattoussi

Beilstein J. Nanotechnol. 2019, 10, 2477–2482, doi:10.3762/bjnano.10.238

• macrophages to these hybrid materials combined with an improvement in their in vivo tumour accumulation [6]. Weil and co-workers described the use of multimodal platforms, made of diamond dots combined with gold nanoparticles, as imaging probes of live cell cultures [7]. We have recently characterized a

• hybrid system consisting of self-assembled gold nanoparticles (AuNPs) and polymer-encapsulated QDs. These constructs were further functionalized with polyhistidine-tagged proteins, yielding functional conjugates that exhibit fluorescent and plasmonic properties [8]. Over the last two decades several

• hydrodynamic size exceeds both the QD construct of our previous study (d(QD-LA) ≈ 10–15 nm [22]) or the virus particle itself (d ≈ 40 nm [21]). Experimental In brief, the functionalized polymer-encapsulated quantum dots were left to incubate with partially capped gold nanoparticles. This conjugate was

Multiwalled carbon nanotube based aromatic volatile organic compound sensor: sensitivity enhancement through 1-hexadecanethiol functionalisation

• Nadra Bohli,
• Meryem Belkilani,
• Juan Casanova-Chafer,
• Eduard Llobet and
• Adnane Abdelghani

Beilstein J. Nanotechnol. 2019, 10, 2364–2373, doi:10.3762/bjnano.10.227

• temperature toluene and benzene sensor based on multiwall carbon nanotubes (MWCNTs) decorated with gold nanoparticles and functionalised with a long-chain thiol self-assembled monolayer, 1-hexadecanethiol (HDT). High-resolution transmission electron microscopy (HRTEM) and Fourier transform infrared

• substrates. They were then decorated with gold nanoparticles via a sputtering technique with a Sputtering ATC Orion 8-HV-AJA International machine [19]. This technique consists of bombarding the surface of a gold disc by a plasma beam, enabling the nanoparticles to cling to the walls of the MWCNTs under the

• [20]. Figure 1 shows the synoptic structure of the sensor before and after the HDT deposition. HRTEM and FTIR characterisation The analysis of the quantity and distribution of the gold nanoparticles attached to the MWCNTs was undertaken with a high-resolution transmission electron microscope (JEOL

Use of data processing for rapid detection of the prostate-specific antigen biomarker using immunomagnetic sandwich-type sensors

• Camila A. Proença,
• Tayane A. Freitas,
• Thaísa A. Baldo,
• Elsa M. Materón,
• Flávio M. Shimizu,
• Gabriella R. Ferreira,
• Frederico L. F. Soares,
• Ronaldo C. Faria and
• Osvaldo N. Oliveira Jr.

Beilstein J. Nanotechnol. 2019, 10, 2171–2181, doi:10.3762/bjnano.10.210

• polyclonal antibody, (3) capture of biomarker by the bioconjugate, (4) sandwich formation by injection of the biomarker captured by Ab2-MNP-HRP in the microfluidic system. The first step included the deposition of a bilayer of poly(diallyldimethylammonium) (PDDA) and gold nanoparticles (AuNPs) decorated with

• glutathione, as illustrated in Figure 7. An aliquot of 5 μL of 2.0 mg·mL−1 of PDDA was added to each working electrode and kept for 20 min. The electrode surface was rinsed with Millipore water to remove excess of reagents. Then, 5.0 μL of gold nanoparticles modified with glutathione (AuNP-GSH, 46.68 µg·mL−1

Gold-coated plant virus as computed tomography imaging contrast agent

• Alaa A. A. Aljabali,
• Mazhar S. Al Zoubi,
• Khalid M. Al-Batanyeh,
• Ali Al-Radaideh,
• Mohammad A. Obeid,
• Abeer Al Sharabi,
• Walhan Alshaer,
• Bayan AbuFares,
• Tasnim Al-Zanati,
• Murtaza M. Tambuwala,
• Naveed Akbar and
• David J. Evans

Beilstein J. Nanotechnol. 2019, 10, 1983–1993, doi:10.3762/bjnano.10.195

• contrast agents including gold nanoparticles (AuNPs) [13], bromine [14], platinum [15], ytterbium [16], gadolinium [4], and tungsten [15]. Many of the systems are made up of a core that is coated with a polymeric material such as liposomes [17], micelles [13], lipoproteins or polymeric nanoparticles [18

Porous silver-coated pNIPAM-co-AAc hydrogel nanocapsules

• William W. Bryan,
• Riddhiman Medhi,
• Maria D. Marquez,
• Supparesk Rittikulsittichai,
• Michael Tran and
• T. Randall Lee

Beilstein J. Nanotechnol. 2019, 10, 1973–1982, doi:10.3762/bjnano.10.194

• hydrogels. Figure 1b shows an image of the pNIPAM-co-AAc hydrogels at high magnification. Using statistical image analysis of the SEM images, the typical size of the hydrogels was determined to be 787 ± 81 nm. To bind the negatively charged THPC gold nanoparticles to the surface of the hydrogel particles

Engineered superparamagnetic iron oxide nanoparticles (SPIONs) for dual-modality imaging of intracranial glioblastoma via EGFRvIII targeting

• Xianping Liu,
• Chengjuan Du,
• Haichun Li,
• Ting Jiang,
• Zimiao Luo,
• Zhiqing Pang,
• Daoying Geng and
• Jun Zhang

Beilstein J. Nanotechnol. 2019, 10, 1860–1872, doi:10.3762/bjnano.10.181

• studied with regard to their long blood half-life [11], easy surface modification and excellent biocompatibility [12]. In the past years, several multifunctional vehicles for glioblastoma imaging have been developed, such as gold nanoparticles [13][14], which were integrated for diagnosis and treatment

Microfluidic manufacturing of different niosomes nanoparticles for curcumin encapsulation: Physical characteristics, encapsulation efficacy, and drug release

• Mohammad A. Obeid,
• Ibrahim Khadra,
• Abdullah Albaloushi,
• Margaret Mullin,
• Hanin Alyamani and
• Valerie A. Ferro

Beilstein J. Nanotechnol. 2019, 10, 1826–1832, doi:10.3762/bjnano.10.177

• unwanted side effects [8][9]. Liposomes, solid lipid nanoparticles, dendrimers, micelles, polymeric nanoparticles, gold nanoparticles, and carbon nanotubes are among the most common types of nanoparticle delivery systems [10]. These efforts have been reported in several studies. For example, Guo et al

Nanoarchitectonics meets cell surface engineering: shape recognition of human cells by halloysite-doped silica cell imprints

• Elvira Rozhina,
• Ilnur Ishmukhametov,
• Svetlana Batasheva,
• Farida Akhatova and
• Rawil Fakhrullin

Beilstein J. Nanotechnol. 2019, 10, 1818–1825, doi:10.3762/bjnano.10.176

• cells templates offer other fascinating opportunities due to their cell-mimicking geometries, for example, a novel class of bioinspired colloid particles was fabricated recently. Colloid antibodies were produced via the formation of solid silica shells doped with gold nanoparticles on bacterial cells

Toxicity and safety study of silver and gold nanoparticles functionalized with cysteine and glutathione

• Barbara Pem,
• Igor M. Pongrac,
• Lea Ulm,
• Ivan Pavičić,
• Valerije Vrček,
• Darija Domazet Jurašin,
• Marija Ljubojević,
• Adela Krivohlavek and
• Ivana Vinković Vrček

Beilstein J. Nanotechnol. 2019, 10, 1802–1817, doi:10.3762/bjnano.10.175

• Zagreb, Croatia 10.3762/bjnano.10.175 Abstract This study was designed to evaluate the nano–bio interactions between endogenous biothiols (cysteine and glutathione) with biomedically relevant, metallic nanoparticles (silver nanoparticles (AgNPs) and gold nanoparticles (AuNPs)), in order to assess the

• with time. Transmission electron micrographs of silver (AgNPs) and gold nanoparticles (AuNPs) prepared in the presence of cysteine (CYS) or glutathione (GSH). (a) Viability of L929 cells exposed to silver (AgNPs) and gold nanoparticles (AuNPs) stabilized with cysteine (CYS) or glutathione (GSH), Ag

• reflective spots (g), while NP reflectance signals are visible as bright red signals and indicated by white arrows (c,d). The effect of silver (AgNPs) and gold nanoparticles (AuNPs) stabilized with cysteine (CYS) or glutathione (GSH), Ag+ and Au3+ ions on (a) total DNA damage and (b) DNA double-stranded

Growth dynamics and light scattering of gold nanoparticles in situ synthesized at high concentration in thin polymer films

• Corentin Guyot,
• Philippe Vandestrick,
• Ingrid Marenne,
• Olivier Deparis and
• Michel Voué

Beilstein J. Nanotechnol. 2019, 10, 1768–1777, doi:10.3762/bjnano.10.172

• inorganic film by, e.g., thermal annealing. Results: Simple laser reflection experiments showed that this growth process induced light scattering at the film/air interface. We report on this phenomenon, considering the growth dynamics of gold nanoparticles in a polymer film. The scattering of light was

• properties of plasmonic nanocomposite materials from experimental, theoretical as well as numerical points of view [1][2]. Metal nanoparticles (NPs) play a central role in the development of nanotechnology-based optical devices. Gold nanoparticles (AuNPs) are used in spectrally selective coatings to block

Highly ordered mesoporous silica film nanocomposites containing gold nanoparticles for the catalytic reduction of 4-nitrophenol

• Mohamad Azani Jalani,
• Leny Yuliati,
• Siew Ling Lee and
• Hendrik O. Lintang

Beilstein J. Nanotechnol. 2019, 10, 1368–1379, doi:10.3762/bjnano.10.135

• synthesis method using discotic trinuclear gold(I) pyrazolate complex, were successfully utilized for the fabrication of thin film mesoporous silica nanocomposites containing gold nanoparticles. The material exhibited a highly ordered hexagonal structure when subjected to a thermal hydrogen reduction

• treatment at 210 °C. In contrast, when the material was subjected to calcination as a heat treatment from 190 to 450 °C, the thin film nanocomposites showed an intense d100 X-ray diffraction peak. Moreover, gold nanoparticles inside the thin film nanocomposites were confirmed by the presence of the d111

• . Such catalytic activity is due to the presence of gold nanoparticles of smaller size in the silicate channels of the highly ordered mesoporous film nanocomposites. Keywords: catalyst; gold nanoparticle; mesoporous silica; nanocomposite; thermal hydrogen reduction; 4-nitrophenol reduction

Construction of a 0D/1D composite based on Au nanoparticles/CuBi₂O₄ microrods for efficient visible-light-driven photocatalytic activity

• Weilong Shi,
• Mingyang Li,
• Hongji Ren,
• Feng Guo,
• Xiliu Huang,
• Yu Shi and
• Yubin Tang

Beilstein J. Nanotechnol. 2019, 10, 1360–1367, doi:10.3762/bjnano.10.134

• content, the photocatalytic degradation rate of TC firstly increased to a maximum of 93% (2.5 wt % Au/CBO), then decreased again when more Au NPs are added to the composite system. This phenomenon may be connected with excessive gold nanoparticles hindering the absorption of visible light. In addition

A silver-nanoparticle/cellulose-nanofiber composite as a highly effective substrate for surface-enhanced Raman spectroscopy

• Yongxin Lu,
• Yan Luo,
• Zehao Lin and
• Jianguo Huang

Beilstein J. Nanotechnol. 2019, 10, 1270–1279, doi:10.3762/bjnano.10.126

• bacterial nanocellulose adsorbed with gold nanoparticles in the form of a hydrogel had a detection limit of 1 × 10−9 M for R6G [54], the Au–Ag bimetallic microfluidic SERS sensor had a detection limit of 1 × 10−13 M for the same analyte [64]; and a detection limit of 1 × 10−6 M was offered by a hybrid

Enhanced inhibition of influenza virus infection by peptide–noble-metal nanoparticle conjugates

• Zaid K. Alghrair,
• David G. Fernig and
• Bahram Ebrahimi

Beilstein J. Nanotechnol. 2019, 10, 1038–1047, doi:10.3762/bjnano.10.104

• ; gold nanoparticles; influenza virus; lytic infection; silver nanoparticles; Introduction The influenza (“flu”) type-A virus is a major health concern for humans and livestock animals. The primary mode of transmission is by the respiratory route. Flu infection occurs seasonally and can cause global

• greater antiviral activity than the free peptide, making this a viable tool for the development of a peptide formulation that efficiently combats seasonal, pandemic, and zoonotic influenza infections. Results and Discussion Stability of FluPep functionalised gold nanoparticles The mixed-matrix ligand

• shell of 70:30 (mol/mol) peptidol and alkanethiol ethylene glycol assembled on gold nanoparticles has a well-characterised stability with respect to ligand exchange and non-specific binding [26][27], but the effect of incorporating the FluPep amino acid sequence at the C-terminus of the CVVVT matrix

Correlation of surface-enhanced Raman scattering (SERS) with the surface density of gold nanoparticles: evaluation of the critical number of SERS tags for a detectable signal

• Vincenzo Amendola

Beilstein J. Nanotechnol. 2019, 10, 1016–1023, doi:10.3762/bjnano.10.102

• assays and nanomedicine. To this end, a crucial parameter is the minimum number of SERS tags that allows for the collection of intense Raman signals under real operating conditions. Here, SERS Au nanotags (AuNTs) based on clustered gold nanoparticles are deposited on a substrate and analyzed in the same

• suitability of plasmonic SERS labels for ultrasensitive analytical and biomedical applications is evident. Keywords: discrete dipole approximation (DDA); gold nanoparticles (AuNPs); nanotags; surface-enhanced Raman scattering (SERS); surface plasmon resonance (SPR); Introduction In surface-enhanced Raman

Structural and optical properties of penicillamine-protected gold nanocluster fractions separated by sequential size-selective fractionation

• Xiupei Yang,
• Zhengli Yang,
• Fenglin Tang,
• Jing Xu,
• Maoxue Zhang and
• Martin M. F. Choi

Beilstein J. Nanotechnol. 2019, 10, 955–966, doi:10.3762/bjnano.10.96

• . We conclude that the AuNCs here are primarily protected by the Au–S bonds. However, we cannot rule out that a small amount of Au–N bonds are present in the clusters. X-ray photoelectron analysis XPS can be used not only to analyze the properties of S–Au bonds in gold nanoparticles, but also to

Self-assembly and wetting properties of gold nanorod–CTAB molecules on HOPG

• Imtiaz Ahmad,
• Floor Derkink,
• Tim Boulogne,
• Pantelis Bampoulis,
• Harold J. W. Zandvliet,
• Hidayat Ullah Khan,
• Rahim Jan and
• E. Stefan Kooij

Beilstein J. Nanotechnol. 2019, 10, 696–705, doi:10.3762/bjnano.10.69

• ][25], catalytic [26][27][28][29], photonic [30][31][32][33][34], plasmonic [35][36][37][38][39], and surface-enhanced Raman scattering (SERS) [40][41][42] applications. In relation to our system consisting of cetyltrimethylammonium bromide (CTAB)-coated gold nanoparticles, it has also been observed

Hydrophilicity and carbon chain length effects on the gas sensing properties of chemoresistive, self-assembled monolayer carbon nanotube sensors

• Juan Casanova-Cháfer,
• Carla Bittencourt and
• Eduard Llobet

Beilstein J. Nanotechnol. 2019, 10, 565–577, doi:10.3762/bjnano.10.58

• the gold nanoparticles creating SAMs (see Figure S2, Supporting Information File 1), which differed in their terminal functional groups and in the length of their carbon chain. This enables studying the effects of hydrophilicity or hydrophobicity of terminal functional groups and carbon chain length

• quantitative XPS results indicating that the Au content was 5.7 wt % in these samples). A monomodal distribution of Au nanoparticles is obtained with average diameter of about 4 nm. The gold nanoparticles appear very close one to another (typically 10 nm apart), which will affect the gas sensing mechanism, as

• will be discussed in detail below. The crystallinity of oxygen-plasma-treated MWCNTs decorated with gold nanoparticles was characterized by Raman spectroscopy. Taking the intensity ratio of the D/G bands into consideration, the material presents a low level of crystallinity with defects caused by the