Integrated photonics multi-waveguide devices for optical trapping and Raman spectroscopy: design, fabrication and performance demonstration

• Gyllion B. Loozen,
• Arnica Karuna,
• Mohammad M. R. Fanood,
• Erik Schreuder and
• Jacob Caro

Beilstein J. Nanotechnol. 2020, 11, 829–842, doi:10.3762/bjnano.11.68

• waveguides. Keywords: Brownian motion; integrated optics devices; lab-on-a-chip; optical trapping; nanofabrication; Raman spectroscopy; ridge waveguides; Introduction Photonic lab-on-a-chip (LOC) techniques strongly attract attention for the manipulation and measurement of biological particles such as

Experimental study of an evanescent-field biosensor based on 1D photonic bandgap structures

• Jad Sabek,
• Francisco Javier Díaz-Fernández,
• Luis Torrijos-Morán,
• Zeneida Díaz-Betancor,
• Ángel Maquieira,
• María-José Bañuls,
• Elena Pinilla-Cienfuegos and
• Jaime García-Rupérez

Beilstein J. Nanotechnol. 2019, 10, 967–974, doi:10.3762/bjnano.10.97

• development of integrated lab-on-a-chip (LOC) devices for the highly sensitive and label-free detection of target analytes is one of the fields arousing high interest over the recent years [1][2]. These devices aim at overcoming some of the drawbacks of the methodologies commonly used today, such as ELISA

Advanced scanning probe lithography using anatase-to-rutile transition to create localized TiO₂ nanorods

• Julian Kalb,
• Vanessa Knittel and
• Lukas Schmidt-Mende

Beilstein J. Nanotechnol. 2019, 10, 412–418, doi:10.3762/bjnano.10.40

• contrast, local light scattering, high-resolution surface roughness gradients or microchannels. This set of extensions for rutile TiO2 nanorod applications is a valuable toolkit for lab-on-a-chip devices [33][34][35]. Recently, we investigated the influence of rutile seed layers on the growth and shape of

Size limits of magnetic-domain engineering in continuous in-plane exchange-bias prototype films

• Alexander Gaul,
• Daniel Emmrich,
• Timo Ueltzhöffer,
• Henning Huckfeldt,
• Hatice Doğanay,
• Johanna Hackl,
• Muhammad Imtiaz Khan,
• Daniel M. Gottlob,
• Gregor Hartmann,
• André Beyer,
• Dennis Holzinger,
• Slavomír Nemšák,
• Claus M. Schneider,
• Armin Gölzhäuser,
• Günter Reiss and
• Arno Ehresmann

Beilstein J. Nanotechnol. 2018, 9, 2968–2979, doi:10.3762/bjnano.9.276

• Background: The application of superparamagnetic particles as biomolecular transporters in microfluidic systems for lab-on-a-chip applications crucially depends on the ability to control their motion. One approach for magnetic-particle motion control is the superposition of static magnetic stray field

Electrodeposition of reduced graphene oxide with chitosan based on the coordination deposition method

• Mingyang Liu,
• Yanjun Chen,
• Chaoran Qin,
• Zheng Zhang,
• Shuai Ma,
• Xiuru Cai,
• Xueqian Li and
• Yifeng Wang

Beilstein J. Nanotechnol. 2018, 9, 1200–1210, doi:10.3762/bjnano.9.111

• incredible potential in the area of lab-on-a-chip devices, biofuel cells and implantable devices [9]. Aminopolysaccharide chitosan is one of the most widely used materials for electrodeposition. Due to its pH-responsive film-forming properties, chitosan can be electrodeposited as a stable film on the cathode

Optimal fractal tree-like microchannel networks with slip for laminar-flow-modified Murray’s law

• Dalei Jing,
• Shiyu Song,
• Yunlu Pan and
• Xiaoming Wang

Beilstein J. Nanotechnol. 2018, 9, 482–489, doi:10.3762/bjnano.9.46

• microfluidic systems widely used in various fields such as lab-on-a-chip for chemical and biomedical detection and microchannel heat sinks for the cooling of electronic systems [1][2], the optimal mass and heat transfer performance is essential, yet challenging. For example, a microchannel heat sink has a

Flexible photonic crystal membranes with nanoparticle high refractive index layers

• Torben Karrock,
• Moritz Paulsen and
• Martina Gerken

Beilstein J. Nanotechnol. 2017, 8, 203–209, doi:10.3762/bjnano.8.22

• area nanostructures. PDMS (Sylgard 184 PDMS by Dow Corning, Midland, MI, USA) is used as the membrane material. It consists of a base polymer (part A) and a curing agent (part B). PDMS received broad attention for the fabrication of microsystems such as microfluidic and lab-on-a-chip systems [16]. It

Low temperature co-fired ceramic packaging of CMOS capacitive sensor chip towards cell viability monitoring

• Niina Halonen,
• Joni Kilpijärvi,
• Maciej Sobocinski,
• Timir Datta-Chaudhuri,
• Antti Hassinen,
• Someshekar B. Prakash,
• Peter Möller,
• Pamela Abshire,
• Sakari Kellokumpu and
• Anita Lloyd Spetz

Beilstein J. Nanotechnol. 2016, 7, 1871–1877, doi:10.3762/bjnano.7.179

• medium above the capacitors. Moreover, the manufacturing of microfluidic channels in the LTCC package was demonstrated. Keywords: capacitance sensing; cell viability; lab-on-a-chip; low temperature co-fired ceramic (LTCC); Introduction Biosafety regulations require ethical, simple, rapid, and cost

• spectroscopy [1], electrochemical quartz crystal microbalance measurements [2], optical sensing [3], impedimetric sensing [4][5][6], and capacitive sensing [7][8][9][10][11]. The lab-on-a-chip (LoC) concept is an excellent way to implement label-free, noninvasive, cost-effective cytotoxicity assessment. LoCs

Viability and proliferation of endothelial cells upon exposure to GaN nanoparticles

• Tudor Braniste,
• Ion Tiginyanu,
• Tibor Horvath,
• Simion Raevschi,
• Serghei Cebotari,
• Marco Lux,
• Axel Haverich and
• Andres Hilfiker

Beilstein J. Nanotechnol. 2016, 7, 1330–1337, doi:10.3762/bjnano.7.124

• [16][17]. At the same time, the huge potential of integration of GaN in nano-optoelectonic devices opens up the possibility to test the material in lab-on-a-chip technologies. In this study, porcine aortic endothelial cells were investigated in direct contact with GaN nanoparticles. GaN is a compound

Highly compact refractive index sensor based on stripe waveguides for lab-on-a-chip sensing applications

• Chamanei Perera,
• Kristy Vernon,
• Elliot Cheng,
• Juna Sathian,
• Esa Jaatinen and
• Timothy Davis

Beilstein J. Nanotechnol. 2016, 7, 751–757, doi:10.3762/bjnano.7.66

• the device too large for lab-on-a-chip applications [3] and requires precise alignments [12][14]. Nano-plasmonic sensors utilising metallic nanostructures can be used to overcome these limitations. In addition, they allow miniaturisation of the overall device size as well as improving the ease of

• light from the same single source [17]. These nano-sized MZI based sensors typically have a sensitivity 10–100 times less than that of the commercially available SPR-prism based sensors, but have the advantage of being more compact and having sufficient sensitivity for being used in some lab-on-a-chip

Finite-size effect on the dynamic and sensing performances of graphene resonators: the role of edge stress

• Chang-Wan Kim,
• Mai Duc Dai and
• Kilho Eom

Beilstein J. Nanotechnol. 2016, 7, 685–696, doi:10.3762/bjnano.7.61

• -frequency dynamic range of nanomechanical resonators has enabled them to be used for development of lab-on-a-chip mass spectrometry [7][8]. For the recent decade, graphene, which is an atomically thin sheet made of carbon atoms, has been highlighted due to its excellent electrical [9][10][11] and mechanical

Novel roles for well-known players: from tobacco mosaic virus pests to enzymatically active assemblies

• Claudia Koch,
• Fabian J. Eber,
• Carlos Azucena,
• Alexander Förste,
• Stefan Walheim,
• Thomas Schimmel,
• Alexander M. Bittner,
• Holger Jeske,
• Hartmut Gliemann,
• Sabine Eiben,
• Fania C. Geiger and
• Christina Wege

Beilstein J. Nanotechnol. 2016, 7, 613–629, doi:10.3762/bjnano.7.54

• enzyme and antibody moieties installed [87][132][134] or engineered [133] at high surface densities on TMV nanocarriers, miniaturized sensor devices might be among the layouts worth extensive testing. Research on microfluidic lab-on-a-chip biodetection systems started in the end of the 20th century, and

• becoming apparent in environmental, food, or intoxication diagnostics (for a recent detailed review, refer to [171]). Lab-on-a-chip solutions may integrate sample preparation and enrichment routines with multiple diagnostic tasks, requiring low total amounts of analytes as well as biorecognition elements

• . Prospects for novel layouts enabling lab-on-a-chip applications and improved orientation of enzymatically active TMV rods. A: Scheme of a microchannel of a glucose sensor chip equipped with a blend of two TMV enzyme nanocarrier species. By an appropriate mixture thereof, an optimally composed two-enzyme

Electroviscous effect on fluid drag in a microchannel with large zeta potential

• Dalei Jing and
• Bharat Bhushan

Beilstein J. Nanotechnol. 2015, 6, 2207–2216, doi:10.3762/bjnano.6.226

• -mechanical systems (MEMS/NEMS) have been realized and widely used. As a significant branch of MEMS/NEMS, micro/nanofluidic systems incorporating micro/nano pumps, valves, mixers, and channels have wide applications, such as micro heat exchangers, drug delivery systems, and lab-on-a-chip bioanalysis [1][2

Imaging of carbon nanomembranes with helium ion microscopy

• André Beyer,
• Henning Vieker,
• Robin Klett,
• Hanno Meyer zu Theenhausen,
• Polina Angelova and
• Armin Gölzhäuser

Beilstein J. Nanotechnol. 2015, 6, 1712–1720, doi:10.3762/bjnano.6.175

• as filters [7], sensors [4], resists [8], nanosieves [9], or “lab-on-a-chip” devices [10]. Many aspects regarding the fabrication, modification and functionalization of homogenous as well as patterned CNMs are compiled in a recent review [11]. Optical microscopy is suitable for imaging CNMs on SiO2

Sorting of droplets by migration on structured surfaces

• Wilfried Konrad and
• Anita Roth-Nebelsick

Beilstein J. Nanotechnol. 2011, 2, 215–221, doi:10.3762/bjnano.2.25

• ; microfluidics; surface; surface energy; surface structures; Introduction Manipulation of droplets is an issue of great interest in microfluidics. The underlying motivation is the design of microdevices that are able to perform various fluidic processes within dimensions on the micrometer scale [1]. “Lab-on-a

• -chip” concepts aim at integrating chemical and biochemical processes into chip-like designs that enable the user to carry out tasks in analytical chemistry or bioassay applications [2]. The design of microfluidic batch processes requires a continuous and controlled flow and cycling of suspended

Microfluidic anodization of aluminum films for the fabrication of nanoporous lipid bilayer support structures

• Jaydeep Bhattacharya,
• Alexandre Kisner,
• Andreas Offenhäusser and
• Bernhard Wolfrum

Beilstein J. Nanotechnol. 2011, 2, 104–109, doi:10.3762/bjnano.2.12

• advantages of using nanoporous membranes as support structures for lipid bilayers, which allows the monitoring of the activity of membrane proteins [26][27][28][29][30]. Although solid lipid support structures [31] may exhibit versatile functionality for lab-on-a-chip applications [32], only porous