Biomimetic nanoparticles in cancer photodynamic therapy: a review of targeted delivery systems and therapeutic outcomes

• Valentina I. Gorbacheva,
• Alexey S. Grabovoy,
• Polina S. Marukhina,
• Anastasiia O. Syrocheva and
• Ekaterina P. Kolesova

Beilstein J. Nanotechnol. 2026, 17, 396–422, doi:10.3762/bjnano.17.27

• regions within the tumors. In 4T1 cells exposed to NIR laser irradiation, membrane-coated nanoparticles generated singlet oxygen with threefold greater efficiency compared to non-coated nanoparticles. In BALB/c mouse models bearing 4T1 tumors, the membrane-coated nanoparticles preferentially accumulated

Polycatecholamine nanocoatings on stainless steel: the effect on attachment of human fibroblasts and platelets

• Paulina Trzaskowska,
• Ewa Rybak,
• Maciej Trzaskowski,
• Kamil Kopeć,
• Jakub Krzemiński,
• Rafał Podgórski,
• Hatice Genc,
• Mehtap Civelek and
• Iwona Cicha

Beilstein J. Nanotechnol. 2026, 17, 365–380, doi:10.3762/bjnano.17.25

• controlled nanoscale surface features in the development of next-generation bioactive coatings for medical implants and blood-contacting devices. Experimental Materials and methods Stainless steel samples Stainless steel 316L discs (14 mm in diameter, 0.8 mm in thickness) were laser-cut by STOMILEX (Poland

Interconnection morphology effects on the radio frequency response of carbon nanotube sponges

• Manuela Scarselli,
• Javad Rezvani,
• Zeno Zuccari,
• Mattia Scagliotti and
• Simone Tocci

Beilstein J. Nanotechnol. 2026, 17, 343–351, doi:10.3762/bjnano.17.23

• using a laser with a wavelength of 532 nm and a power of approximately 15 mW. The photon energy was calibrated using a Si reference. The measurements were performed using a monochromator with 1800 lines·mm−1. The laser power was optimised to prevent laser-induced damage. XPS surface analysis studies

Beam shaping techniques for pulsed laser ablation in liquids: Unlocking tunable control of nanoparticle synthesis in liquids

• Sergio Molina-Prados,
• Nadezhda M. Bulgakova,
• Alexander V. Bulgakov,
• Jesus Lancis,
• Gladys Mínguez Vega and
• Carlos Doñate-Buendia

Beilstein J. Nanotechnol. 2026, 17, 309–342, doi:10.3762/bjnano.17.22

• 10.3762/bjnano.17.22 Abstract Nanoparticle synthesis via pulsed laser ablation in liquids has gained prominence as a versatile and environmentally friendly approach for producing ligand-free colloids with controlled composition, size, and morphology. While pulsed laser ablation in liquids offers

• unparalleled advantages in terms of nanoparticle purity and material versatility, enhancing the size control and productivity require modifications of the standard pulsed laser ablation in liquids technique, such as the incorporation of beam shaping techniques. Recent developments in spatial and temporal beam

• shaping have demonstrated their potential to revolutionise pulsed laser ablation in liquids by enabling more precise energy deposition and modified nanoparticle production dynamics. This review highlights the critical role of beam shaping, encompassing spatial shaping of the beam to influence laser

Fast vortex dynamics and relaxation times in NbRe-based heterostructures

• Francesco De Chiara,
• Zahra Makhdoumi Kakhaki,
• Francesco Avitabile,
• Francesco Colangelo,
• Abhishek Kumar,
• Carmine Attanasio and
• Carla Cirillo

Beilstein J. Nanotechnol. 2026, 17, 292–302, doi:10.3762/bjnano.17.20

• optical lithography using a direct laser writer exposure followed by an ion-etching procedure. This technique results in microstrips with straight edges, ensuring a uniform width, w, of the device [39]. The geometrical values of the microstrips are reported in Table 1. Electrical contacts were realized

Multilayered hyperbolic Au/TiO₂ nanostructures for enhancing the nonlinear response around the epsilon-near-zero point

• Fernando Arturo Araiza-Sixtos,
• Mauricio Gomez-Robles,
• Rafael Salas-Montiel and
• Raúl Rangel-Rojo

Beilstein J. Nanotechnol. 2026, 17, 251–261, doi:10.3762/bjnano.17.17

• laser, enabling us to characterize both the refractive and absorptive contributions to the nonlinear response. Due to the high pulse repetition rate inherent to Ti:sapphire systems and the presence of linear absorption in the samples, cumulative pulse-to-pulse thermal effects may be present. A modified

• version of the z-scan technique that allowed us to separate the electronic from the thermal contribution was used. A clear enhancement of the nonlinear response was observed for the sample with an ENZ point around the laser wavelength 800 nm with a nonlinear refractive index of n2 = 0.103 ± 0.006 cm2·GW−1

• tune the material to the laser wavelength rather than the other way around. We make a characterization of the linear optical properties of the samples and present a study of the nonlinear optical properties. For the linear characterization of the samples, we study the absorption using spectrophotometry

Gold nanoparticle-decorated reduced graphene oxide as a highly effective catalyst for the selective α,β-dehydrogenation of N-alkyl-4-piperidones

• Brenda Flore Kenyim,
• Mihir Tzalis,
• Marilyn Kaul,
• Robert Oestreich,
• Aysenur Limon,
• Chancellin Pecheu Nkepdep and
• Christoph Janiak

Beilstein J. Nanotechnol. 2026, 17, 218–238, doi:10.3762/bjnano.17.15

Structure-dependent thermochromism of PAZO thin films: theory and experiment

• Georgi Mateev,
• Dean Dimov,
• Nataliya Berberova-Buhova,
• Nikoleta Kircheva,
• Todor Dudev,
• Ludmila Nikolova,
• Elena Stoykova,
• Keehoon Hong,
• Dimana Nazarova,
• Silvia Angelova and
• Lian Nedelchev

Beilstein J. Nanotechnol. 2026, 17, 186–199, doi:10.3762/bjnano.17.12

• prepared for the study. Two of them underwent thermal treatment at 200 °C for 1 h, resulting in the emergence of a new absorption band with a peak in the 460–475 nm range. Birefringence was then induced in pairs of samples using 444 and 532 nm laser illumination. Following sample treatment and laser

• under laser illumination at 532 nm. To emphasize these changes, we plotted in the Figure 4D the spectra of the untreated PAZO sample and the thermally treated one. Quantitative interpretation of the obtained P and S absorption spectra can be done by calculating an order parameter, Sorder, from the

• started approximately 1 h after the samples had cooled down to r.t. The corresponding data are presented in Figure 5. From the results it is evident that thermal treatment does not enhance the birefringence (∆n) when the pump laser wavelength is 444 nm. In contrast, a significant improvement is observed

Influence of surface characteristics on the in vitro stability and cell uptake of nanoliposomes for brain delivery

• Dushko Shalabalija,
• Ljubica Mihailova,
• Nikola Geskovski,
• Andreas Zimmer,
• Otmar Geiss,
• Sabrina Gioria,
• Diletta Scaccabarozzi and
• Marija Glavas Dodov

Beilstein J. Nanotechnol. 2026, 17, 139–158, doi:10.3762/bjnano.17.9

• outlet of the MWD detector was connected to a DAWN 8+ HELEOS II MALS operating with a 658 nm laser (Wyatt Technology Europe). A DLS (Malvern Zetasizer Nano-S, UK) with an installed quartz flow cell (ZEN0023) was also used in this study in flow mode. Refractive index (RI) and absorption parameters were

• acidic environment (for visualization of endocytic pathways). Further, the cells were stained and visualized as described above. Internalization studies of nanoliposomes in hCMEC/D3 cells by confocal microscopy Confocal laser scanning microscopy (Carl Zeiss, Axiovert 200M Inverted Microscope) was

• ± 0.81 to 140.20 ± 0.95 nm (PDI < 0.256). The data in the literature suggests that DLS is widely employed for sizing liposomes and other colloidal materials. It operates by detecting laser light scattered due to the Brownian motion of particles or macromolecules in suspension, with the scattering

Reduced graphene oxide paper electrode for lithium-ion cells – towards optimized thermal reduction

• Agata Pawłowska,
• Magdalena Baran,
• Stefan Marynowicz,
• Aleksandra Izabela Banasiak,
• Adrian Racki,
• Adrian Chlanda,
• Tymoteusz Ciuk,
• Marta Wolczko and
• Andrzej Budziak

Beilstein J. Nanotechnol. 2026, 17, 24–37, doi:10.3762/bjnano.17.3

• samples per material, that is, M300, T400, T600, and T800. Raman spectroscopy The structural properties of the rGO paper sheets were studied with Raman spectroscopy (InVia Renishaw spectrometer). The spectra were collected with three accumulations, a 10 s exposure time, and 1% laser power (laser

Quantitative estimation of nanoparticle/substrate adhesion by atomic force microscopy

• Aydan Çiçek,
• Markus Kratzer,
• Christian Teichert and
• Christian Mitterer

Beilstein J. Nanotechnol. 2026, 17, 1–14, doi:10.3762/bjnano.17.1

• cantilever deflection as well as torsional spring constant [39]. However, errors can arise due to the sensitivity of the PSPD to laser alignment and a few micrometers offset from the tip shear center, leading to erroneous determination of the cantilever torsion loop offset. As a result, there is very low

Internal 3D temperature mapping in biological systems using ratiometric light-sheet imaging and lipid-coated upconversion nanothermometers

• Dannareli Barron-Ortiz,
• Enric Pérez-Parets,
• Rubén D. Cadena-Nava,
• Emilio J. Gualda,
• Jacob Licea-Rodríguez,
• Juan Hernández-Cordero,
• Pablo Loza-Álvarez and
• Israel Rocha-Mendoza

Beilstein J. Nanotechnol. 2025, 16, 2306–2316, doi:10.3762/bjnano.16.159

• NIR excitation at 980 nm was provided by a fiber Bragg grating-stabilized laser (JDSU, 2900 Series), with collimated light focused onto the back focal plane of a 4×/0.13 NA excitation objective (Nikon, PlanFluor) using a 250 mm cylindrical lens (Thorlabs, LJ1267RM-A). The excitation objective

• metabolism to organ-specific stress responses. Characteristic UC fluorescent emission spectra of NaYF4:Er3+/Yb3+ in the green region when irradiated with 980 nm laser light. Insets: UC process scheme (right). Schematic representation of the energy transfer between Yb3+ and Er3+ ions and the UC emission in an

Visualizing nanostructures in supramolecular hydrogels: a correlative study using confocal and cryogenic scanning electron microscopy

• Shaun M. Smith,
• Ferdinando Malagreca,
• Jacqueline Hicks,
• Giuseppe Mantovani,
• David B. Amabilino,
• Christopher Parmenter and
• Lluïsa Pérez-García

Beilstein J. Nanotechnol. 2025, 16, 2274–2284, doi:10.3762/bjnano.16.156

• ) fluorophores were imaged using confocal laser scanning microscopy (CLSM) of fully solvated gels and cryogenic scanning electron microscopy (cryo-SEM) was used to observe the corresponding xerogels. The DPP@Gel systems exhibit strong fluorescence and are effectively imaged using CLSM, with fibre morphologies

• even then, excitation laser intensities had to be operated at or near their maximum fluence to obtain images with good signal-to-noise ratio. This elevated laser power then contributed to a certain extent of fluorophore bleaching, making effective imaging even more challenging. Despite these measures

• . The significantly stronger fluorescence emission of the DPP derivatives under moderate laser excitation (a low percentage of the maximum possible irradiance) enabled individual fibrillar structures to be visualized clearly without the need to compress the gel between glass slides, thus preserving the

Chiral plasmonic nanostructures fabricated with circularly polarized light

• Tian Qiao and
• Ming Lee Tang

Beilstein J. Nanotechnol. 2025, 16, 2245–2264, doi:10.3762/bjnano.16.154

• -assisted hydrolysis with relatively low-energy electrons (≈1.5 eV compared to >10 eV at the hot spots) at the lateral sides of AuNRs. In contrast, polymethyl(methacrylate) (PMMA) decomposed preferentially at the hot spots of the AuNRs under femtosecond laser excitation by high-energy hot electrons

• ) measures the interaction between electrons and cPNSs upon laser excitation by mapping the EELS within an electron microscope [135] (Figure 8e). In summary, we have reviewed the nanoscale characterization tools correlating structure to chiroptical activity of PNSs in this section. CD and ORD are handy tools

Optical bio/chemical sensors for vitamin B₁₂ analysis in food and pharmaceuticals: state of the art, challenges, and future outlooks

• Seyed Mohammad Taghi Gharibzahedi and
• Zeynep Altintas

Beilstein J. Nanotechnol. 2025, 16, 2207–2244, doi:10.3762/bjnano.16.153

• newer studies on the ECL sensors compared to CL sensors to detect VB12. Bhaiyya et al. have recently fabricated a novel laser-induced graphene (LIG)-based ECL system with two and three channels to detect H2O2, VB12, and vitamin C (VC) from real samples. VB12 and VC acted as the recognition analytes, the

Ultrathin water layers on mannosylated gold nanoparticles

• Maiara A. Iriarte Alonso,
• Jorge H. Melillo,
• Silvina Cerveny,
• Yujin Tong and
• Alexander M. Bittner

Beilstein J. Nanotechnol. 2025, 16, 2183–2198, doi:10.3762/bjnano.16.151

• evaporated under nitrogen flow. The VSFG experiments were achieved under dry air flushing at room temperature (24 °C) at four different center frequencies to measure the complete CH and OH stretching region in the broadband infrared. The tunable infrared laser produced femtosecond pulses of ca. 5.5 mW (at

• for ppp polarization (all beams polarized normal to the surface) and 2 min for ssp (laser beams polarized parallel to the surface, sum frequency emission and up-conversion polarized perpendicular and infrared parallel to the plane of incidence). Electron microscopy imaging SEM and STEM images were

Toward clinical translation of carbon nanomaterials in anticancer drug delivery: the need for standardisation

• Michał Bartkowski,
• Francesco Calzaferri and
• Silvia Giordani

Beilstein J. Nanotechnol. 2025, 16, 2092–2104, doi:10.3762/bjnano.16.144

• , laser ablation, or electrochemical techniques, among others. These CNMs must then be thoroughly characterised to confirm their structural and physicochemical properties, including size, shape, charge, surface functionality, stability, and potential toxicity. Following characterisation, anticancer

• main issues is the wide variety of methods that can be used to synthesise CNMs, which can lead to variations in their properties and performance. For example, carbon nanotubes can be synthesised using arc discharge, laser ablation, and chemical vapour deposition, among others [30]. Each method can

Calibration of piezo actuators and systems by dynamic interferometry

• Knarik Khachatryan and
• Michael Reichling

Beilstein J. Nanotechnol. 2025, 16, 2086–2091, doi:10.3762/bjnano.16.143

• . Experiments are performed with laser light of wavelength λ = λvac = 780.41 nm and the excitation frequency is kept at the cantilever eigenfrequency fexc = 169.667 kHz determined at the beginning of the measurements. The piezoelectric tube (PZT-8, EBL Products Inc., East Hartford, CT, USA) used for fiber

• measurement has been performed many weeks earlier. The difference in calibration results for measurements taken with significant time elapsed between can be explained by slight differences in the alignment of the laser spot on the cantilever due to manual adjustment or drift. Although, in our models, light is

• treated as a plane wave, in reality the light beam exiting the fiber end has a divergence of about 9°. As a consequence, light diffracted at the edges of the cantilever acts back on the reflected light sampled by the fiber. Furthermore, the partially coherent light of the laser produces speckle patterns

Laser ablation in liquids for shape-tailored synthesis of nanomaterials: status and challenges

• Natalie Tarasenka

Beilstein J. Nanotechnol. 2025, 16, 1963–1997, doi:10.3762/bjnano.16.137

• . Despite many synthesis methods are still mainly focused on the production of near-spherical NPs, a number of emerging applications require nanomaterials of nonspherical shape and developed surface, which determine the functional performance of nanostructured devices. Laser ablation in liquids has been

• demonstrated as a clean, simple, and versatile NP synthesis method. However, the conditions of NP formation and growth are favouring the production of spherical NPs. There are fewer studies of shape control during laser ablation. With that in mind, this perspective article represents a view on the current

• stage of the development of laser ablation in liquids from the perspective of shape control of the forming nanomaterials. The key parameters influencing the NP shape are highlighted, including the composition of a liquid, laser focusing conditions and introduction of external fields, and the mechanism

Evaluating metal-organic precursors for focused ion beam-induced deposition through solid-layer decomposition analysis

• Benedykt R. Jany,
• Katarzyna Madajska,
• Aleksandra Butrymowicz-Kubiak,
• Franciszek Krok and
• Iwona B. Szymańska

Beilstein J. Nanotechnol. 2025, 16, 1942–1951, doi:10.3762/bjnano.16.135

• deposition, chemical mechanical polishing, and laser nanopatterning, enable the creation of nanostructures and nanoscale devices. However, a major limitation of these methods is their inability to effectively produce high-resolution three-dimensional nanostructures [1][2][3][4]. In contrast, focused electron

Further insights into the thermodynamics of linear carbon chains for temperatures ranging from 13 to 300 K

• Alexandre Rocha Paschoal,
• Thiago Alves de Moura,
• Juan S. Rodríguez-Hernández,
• Carlos William de Araujo Paschoal,
• Yoong Ahm Kim,
• Morinobu Endo and
• Paulo T. Araujo

Beilstein J. Nanotechnol. 2025, 16, 1818–1825, doi:10.3762/bjnano.16.125

• 0.86) were identified using 514.5 nm, while two LCC with N = 40 and 50 (γP = 0.67 and 0.81, respectively) were identified using 568.2 nm. In agreement with the literature [29][30], the use of different laser lines does not influence the response of the LCC@MWCNT to different T, but it might excite LCC

Electrical, photocatalytic, and sensory properties of graphene oxide and polyimide implanted with low- and medium-energy silver ions

• Josef Novák,
• Eva Štěpanovská,
• Petr Malinský,
• Vlastimil Mazánek,
• Jan Luxa,
• Ulrich Kentsch and
• Zdeněk Sofer

Beilstein J. Nanotechnol. 2025, 16, 1794–1811, doi:10.3762/bjnano.16.123

• laser (532 nm, 50 mW) and a 50× magnification objective. For ATR-FTIR measurements, a NICOLET iS50R FTIR spectrometer (Thermo Scientific, USA) was employed. The measurements, spanning the range of 4000–400 cm−1 at a resolution of 4 cm−1, utilized a diamond ATR crystal and a DTGS detector for precise

Bioinspired polypropylene-based functionally graded materials and metamaterials modeling the mistletoe–host interface

• Lina M. Rojas González,
• Naeim Ghavidelnia,
• Christoph Eberl and
• Max D. Mylo

Beilstein J. Nanotechnol. 2025, 16, 1592–1606, doi:10.3762/bjnano.16.113

• outside. Once the molding grids had been filled with the base material, they were carefully removed, and hot compression was carried out. Tensile specimens were cut from the laminate using a laser cutter (MT-7050W100, Maitech, Milan, Italy) with a single cycle at a laser speed of 10 mm/s and a power of 30

• could be cut out of the laminate in the width. Figure 2 provides an overview of the tensile specimen designs and their respective fiber content distribution and dimensions. Furthermore, two 2D metamaterials with triangular unit cell configurations were laser cut from the hot-pressed laminates of graded

• ., inversely graded metamaterial, Figure 2I). Glass fiber content analysis X-ray microtomographic (μCT) scans were used to determine the glass fiber content along a linearly graded specimen with rectilinear interfaces and to estimate the heating effects of laser cutting at the specimen edges. Sections of about

Photocatalytic degradation of ofloxacin in water assisted by TiO₂ nanowires on carbon cloth: contributions of H₂O₂ addition and substrate absorbability

• Iram Hussain,
• Lisha Zhang,
• Zhizhen Ye and
• Jin-Ming Wu

Beilstein J. Nanotechnol. 2025, 16, 1567–1579, doi:10.3762/bjnano.16.111

• diffractometer (Rigaku Corporation) with Cu Kα radiation, operating at 40 kV and 35 mA. Raman spectra were obtained using an Alpha300R UV system (WITec, Germany) equipped with a TEM00 laser at a wavelength of 532 nm. X-ray photoelectron spectroscopy (XPS) characterizations were conducted using a Kratos AXIS

Influence of laser beam profile on morphology and optical properties of silicon nanoparticles formed by laser ablation in liquid

• Natalie Tarasenka,
• Vladislav Kornev,
• Alena Nevar and
• Nikolai Tarasenko

Beilstein J. Nanotechnol. 2025, 16, 1533–1544, doi:10.3762/bjnano.16.108

• Abstract In this study, silicon nanoparticles (NPs) were produced by pulsed laser ablation in a liquid, aiming to investigate the influence of a laser beam profile on the properties of the resultant NPs. Morphology, inner structure, and phase composition of the formed NPs were characterized by means of

• ultraviolet–visible spectroscopy, high-resolution transmission electron microscopy, and Raman and photoluminescence spectroscopies, and the correlation of the NP properties with the laser beam profile was studied. Three different beam profiles were selected, namely, a Bessel beam produced using an axicon, an

• annular profile formed using a combination of an axicon and a converging lens, and a Gaussian beam focused on the surface of a Si target using the same converging lens. In all the schemes, a nanosecond Nd3+:YAG laser with a pulse duration of 10 ns operating at its fundamental harmonic (1064 nm) was used