Microplastic pollution in Himalayan lakes: assessment, risks, and sustainable remediation strategies

• Sameeksha Rawat,
• S. M. Tauseef and
• Madhuben Sharma

Beilstein J. Nanotechnol. 2025, 16, 2144–2167, doi:10.3762/bjnano.16.148

• key mechanism in remote lakes besides direct input [7]. Groundwater modeling methods have been instrumental in describing the transport and fate of contaminants, including MPs, in subsurface environments. Numerical methods such as MODFLOW coupled with transport methods such as MT3DMS and RT3D are

• glaciers has been identified as a distinct mechanism for MPs in the ecosystems of the Himalayas. MPs trapped in glacier ice are released as it melts, subsequently entering freshwater streams and lakes downstream [23]. Recently sampling in Pangong Lake and Beas catchment [2] has linked MP presence to

• them are new electrochemical technologies, membrane separation technologies, microbial technologies, and AOPs. The efficiency, mechanism, strengths, weaknesses, and applications of each technology are utilized to assess each technology. These technologies are indicative of the multidimensional

Electron transport through nanoscale multilayer graphene and hexagonal boron nitride junctions

• Aleksandar Staykov and
• Takaya Fujisaki

Beilstein J. Nanotechnol. 2025, 16, 2132–2143, doi:10.3762/bjnano.16.147

• approximately 20%, unlike the one order of magnitude in the case of graphene. Our understanding is that, in the h-BN junctions with and without Stone–Wales defect, the dominant transport mechanism is tunneling, which is not affected significantly by interaction of the h-BN with Stone–Wales defect with the Pt

Rapid synthesis of highly monodisperse AgSbS₂ nanocrystals: unveiling multifaceted activities in cancer therapy, antibacterial strategies, and antioxidant defense

• Funda Ulusu,
• Adem Sarilmaz,
• Yakup Ulusu,
• Faruk Ozel and
• Mahmut Kus

Beilstein J. Nanotechnol. 2025, 16, 2105–2115, doi:10.3762/bjnano.16.145

• bacterial cell wall and cell disruption when the NCs enter into the cell [39]. Thus, induction of apoptosis in bacterial cells occurs, resulting in an inevitable antibacterial mechanism of action. The data shows that the synthesized NCs in the study can be used as an antimicrobial agent in various

• radicals by donating electrons, thereby stabilizing these reactive species and mitigating potential cellular damage. The primary mechanism of action for the synthesized nanoparticles in this study is likely to involve electron donation to the DPPH radical [50]. Consistent with the DPPH results, the FRAP

• scavenging data, the FRAP outcome supports a dual-mechanism antioxidant model (both radical quenching and electron transfer). This suggests that the surface chemistry of AgSbS2 NCs effectively mediates both redox and radical-based pathways, making them promising candidates for applications requiring moderate

Multifrequency AFM integrating PeakForce tapping and higher eigenmodes for heterogeneous surface characterization

• Yanping Wei,
• Jiafeng Shen,
• Yirong Yao,
• Xuke Li,
• Ming Li and
• Peiling Ke

Beilstein J. Nanotechnol. 2025, 16, 2077–2085, doi:10.3762/bjnano.16.142

• (Figure 2B–D). With the free vibration amplitude of the eigenmode being low, this inherent damping mechanism ensures that superimposed vibrations do not significantly perturb the peak force magnitude during tip–sample interaction. Second, the dedicated signal processing scheme detailed in Section

• processes [6][26], complementing the absolute force measurements obtained from the quasi-static PeakForce feedback loop. This dual-mechanism approach enables the detection of a broad range of near-surface properties, including elastic modulus, viscoelasticity, and dissipation, greatly enhancing material

• -eigenmode oscillation acts as a highly sensitive sensor for detecting the aforementioned interaction gradients. Employing low oscillation amplitudes under modal vibration conditions is a well-established strategy that has been proven to further enhance sensitivity [26][27][28]. The underlying mechanism is

Molecular and mechanical insights into gecko seta adhesion: multiscale simulations combining molecular dynamics and the finite element method

• Yash Jain,
• Saeed Norouzi,
• Tobias Materzok,
• Stanislav N. Gorb and
• Florian Müller-Plathe

Beilstein J. Nanotechnol. 2025, 16, 2055–2076, doi:10.3762/bjnano.16.141

• structures on their feet [1][2]. This bioadhesion mechanism has been studied extensively, especially for biomimetic adhesive applications [3][4][5][6][7][8][9]. Understanding these interactions presents a formidable challenge in biophysics and materials science due to the extremely small length and time

• final detachment. This two-stage detachment mechanism, where the pad peels off first, followed by the tip, is clearly visible in the contact profile, where the number of contacts sharply dropped to a non-zero plateau before eventually dropping to zero. The animations in Supporting Information File 2

Beyond the shell: exploring polymer–lipid interfaces in core–shell nanofibers to carry hyaluronic acid and β-caryophyllene

• Aline Tavares da Silva Barreto,
• Francisco Alexandrino-Júnior,
• Bráulio Soares Arcanjo,
• Paulo Henrique de Souza Picciani and
• Kattya Gyselle de Holanda e Silva

Beilstein J. Nanotechnol. 2025, 16, 2015–2033, doi:10.3762/bjnano.16.139

• pores. The pore formation on the shell surface is a potential mechanism for regulating the release of the core content [56][57]. A biomedical scaffold must possess suitable pore size and a high level of porosity. The porosity of the scaffold in tissue engineering applications should be adequate. A study

• of the core, suggests a viable mechanism for the controlled release of active ingredients through diffusion. The high surface hydrophobicity of the nanofibers, confirmed by contact angle measurements, reinforces their potential use in applications that require low tissue adhesion, such as non

The cement of the tube-dwelling polychaete Sabellaria alveolata: a complex composite adhesive material

• Emilie Duthoo,
• Aurélie Lambert,
• Pierre Becker,
• Carla Pugliese,
• Jean-Marc Baele,
• Arnaud Delfairière,
• Matthew J. Harrington and
• Patrick Flammang

Beilstein J. Nanotechnol. 2025, 16, 1998–2014, doi:10.3762/bjnano.16.138

• of inspiration for developing biomimetic adhesives. However, a thorough understanding of their composition and operating mechanism is essential for advancing such applications. Sabellariid tubeworms are model organisms in bioadhesion research, and their adhesive system has been characterized in

Laser ablation in liquids for shape-tailored synthesis of nanomaterials: status and challenges

• Natalie Tarasenka

Beilstein J. Nanotechnol. 2025, 16, 1963–1997, doi:10.3762/bjnano.16.137

• stage of the development of laser ablation in liquids from the perspective of shape control of the forming nanomaterials. The key parameters influencing the NP shape are highlighted, including the composition of a liquid, laser focusing conditions and introduction of external fields, and the mechanism

• shown below. However, obtaining the information on spatial and temporal evolution of transient laser-induced plasma represents a challenge due to the short plasma lifetime. 1.1 Plasma formation and propagation In a widely accepted mechanism of PLAL, the formation of NPs occurs via two major processes

• : thermal evaporation and explosive ejection [1]. According to the thermal evaporation mechanism, the action of a laser beam on the surface of a solid target initiates the absorption of the laser pulse energy. This results in initiation of melting and ionization with the formation of a plasma plume near the

Mechanical property measurements enabled by short-term Fourier-transform of atomic force microscopy thermal deflection analysis

• Thomas Mathias,
• Roland Bennewitz and
• Philip Egberts

Beilstein J. Nanotechnol. 2025, 16, 1952–1962, doi:10.3762/bjnano.16.136

• technique, spectral analysis of the thermal motion in the deflection of AFM cantilevers has shown promise as a lower-cost, less equipment-intensive mechanism to access the dynamic and time-evolving oscillatory characteristics of the cantilever [11][12][13][14][15][16]. In these techniques, the cantilever

Quantum circuits with SINIS structures

• Mikhail Tarasov,
• Mikhail Fominskii,
• Aleksandra Gunbina,
• Artem Krasilnikov,
• Maria Mansfeld,
• Dmitrii Kukushkin,
• Andrei Maruhno,
• Valeria Ievleva,
• Mikhail Strelkov,
• Daniil Zhogov,
• Konstantin Arutyunov,
• Vyacheslav Vdovin,
• Vladislav Stolyarov and
• Valerian Edelman

Beilstein J. Nanotechnol. 2025, 16, 1931–1941, doi:10.3762/bjnano.16.134

• an energy much higher than the thermal energy, the quantum absorption mechanism is already realized, and the real absorption picture becomes much more complicated [19]. It is necessary to take into account many other parameters and relaxation mechanisms. An example of the thermalization process of a

PEGylated lipids in lipid nanoparticle delivery dynamics and therapeutic innovation

• Peiyang Gao

Beilstein J. Nanotechnol. 2025, 16, 1914–1930, doi:10.3762/bjnano.16.133

• [70]. Complement activation plays a central role in mediating PEG immunogenicity. When anti-PEG antibodies bind to PEGylated LNPs, they can activate the complement cascade via classical pathways. This mechanism leads to the deposition of complement proteins C3 and C5b-9 on the nanoparticle surface

Targeting the vector of arboviruses Aedes aegypti with nanoemulsions based on essential oils: a review with focus on larvicidal and repellent properties

• Laryssa Ferreira do Nascimento Silva,
• Douglas Dourado,
• Thayse Silva Medeiros,
• Mariana Alice Gonzaga Gabú,
• Maria Cecilia Queiroga dos Santos,
• Daiane Rodrigues dos Santos,
• Mylena Lemos dos Santos,
• Gabriel Bezerra Faierstein,
• Rosângela Maria Rodrigues Barbosa and
• Fabio Rocha Formiga

Beilstein J. Nanotechnol. 2025, 16, 1894–1913, doi:10.3762/bjnano.16.132

• , volatility, and skin permeation of the active compounds, prolonging the repellent effect due to the controlled release of these compounds [151][152]. The mechanism of action may involve interference with the olfactory system of the mosquitoes, masking host signals and disrupting orientation behavior [147

Programmable soliton dynamics in all-Josephson-junction logic cells and networks

• Vsevolod I. Ruzhickiy,
• Anastasia A. Maksimovskaya,
• Sergey V. Bakurskiy,
• Andrey E. Schegolev,
• Maxim V. Tereshonok,
• Mikhail Yu. Kupriyanov,
• Nikolay V. Klenov and
• Igor I. Soloviev

Beilstein J. Nanotechnol. 2025, 16, 1883–1893, doi:10.3762/bjnano.16.131

• diverse dynamical modes. By introducing a structural asymmetry into a transmission line, we implement a Josephson diode that enforces unidirectional soliton propagation. The programmability of the kinetic inductance then provides a crucial mechanism to selectively enable or disable this diode

• . When α > αcrit, the soliton velocity is a monotonically increasing function of the damping. This dependence falls into an approximately linear regime for α > 3. The physical mechanism for this velocity increase can be understood from the RCSJ model; a higher value of α enhances the resistive

• -dependent transmission and annihilation is the core mechanism that allows the KICK to function as a memory element or a dynamic routing switch. Beyond primary operational modes, the system exhibits other notable behavior types in specific regions of its parameter space. The M-Mode, for instance, is

Self-assembly and adhesive properties of Pollicipes pollicipes barnacle cement protein cp19k: influence of pH and ionic strength

• Shrutika Sawant,
• Anne Marie Power and
• J. Gerard Wall

Beilstein J. Nanotechnol. 2025, 16, 1863–1872, doi:10.3762/bjnano.16.129

• timescale of fibrillogenesis likely preventing premature adhesive curing within the gland prior to secretion. Overall, our findings support a model in which cp19k undergoes pH- and salt concentration-dependent self-assembly into fibrils in the cement gland, with implications for the mechanism and timing of

Current status of using adsorbent nanomaterials for removing microplastics from water supply systems: a mini review

• Nguyen Thi Nhan and
• Tran Le Luu

Beilstein J. Nanotechnol. 2025, 16, 1837–1850, doi:10.3762/bjnano.16.127

• , and the main mechanism involved electrostatic attractions between the positive charge of MPs and negatively charge of GAC [58]. Metal-organic frameworks. MOFs are highly ordered crystalline materials characterized by high porosity and large surface area (Figure 3). Their pore size, volume, and

• ., “Catalytic degradation of polyethylene terephthalate microplastics by Co-N/C@CeO2 composite in thermal-assisted activation PMS system: Process mechanism and toxicological analysis”, Article No. 163192, Copyright (2025), with permission from Elsevier. This content is not subject to CC BY 4.0. Illustration of

Phytol-loaded soybean oil nanoemulsion as a promising alternative against Leishmania amazonensis

• Victória Louise Pinto Freire,
• Mariana Farias Alves-Silva,
• Johny W. de Freitas Oliveira,
• Matheus de Freitas Fernandes-Pedrosa,
• Alianda Maira Cornélio,
• Marcelo de Souza-Silva,
• Thayse Silva Medeiros and
• Arnóbio Antônio da Silva Junior

Beilstein J. Nanotechnol. 2025, 16, 1826–1836, doi:10.3762/bjnano.16.126

• and in vivo investigations to confirm its efficacy, tissue distribution, and mechanism of action. Experimental Material ʟ-α-Phosphatidylcholine (95%) (Avanti Polar lipids, United States); polaxamer 407 (Sigma-Aldrich, Brazil); glycerin (Vetec, Brazil); phytol (97%), mixture of isomers (Sigma-Aldrich

Piezoelectricity of layered double hydroxides: perspectives regarding piezocatalysis and nanogenerators

• Evgeniy S. Seliverstov,
• Evgeniya A. Tarasenko and
• Olga E. Lebedeva

Beilstein J. Nanotechnol. 2025, 16, 1812–1817, doi:10.3762/bjnano.16.124

• current output. The piezoelectric potential generated in the ZnO nanosheets functions as an applied voltage, facilitating charge storage within the LDH layers, which act as capacitors. This mechanism leads to enhanced voltage and current pulses under mechanical stimulation. LDHs can also enhance the

• for activating peroxymonosulfate (PMS) to degrade norfloxacin [9]. The obtained catalyst demonstrated effective degradation within 15 min, achieving a degradation efficiency of 91.50% and a rate constant of 0.1644 min−1. In this study, the main PMS activation mechanism was non-radical. The

Electrical, photocatalytic, and sensory properties of graphene oxide and polyimide implanted with low- and medium-energy silver ions

• Josef Novák,
• Eva Štěpanovská,
• Petr Malinský,
• Vlastimil Mazánek,
• Jan Luxa,
• Ulrich Kentsch and
• Zdeněk Sofer

Beilstein J. Nanotechnol. 2025, 16, 1794–1811, doi:10.3762/bjnano.16.123

• collisions dominate the energy loss mechanism. This results in intense atomic displacements near the surface, leading to significant surface damage, defect formation, and localized modifications within a shallow depth (Rp = 25–27 nm). The opposite situation occurs when both GO and PI were implanted with 1.5

• the polyimide surface layer occurs, the main mechanism being defect formation and partial cleavage of the polymer chains. However, the resulting graphitic regions are not yet sufficiently interconnected and, therefore, the surface resistance remains relatively high. As the fluence increases to 3.75

Exploring the potential of polymers: advancements in oral nanocarrier technology

• Rousilândia de Araujo Silva,
• Igor Eduardo Silva Arruda,
• Luise Lopes Chaves,
• Mônica Felts de La Roca Soares and
• Jose Lamartine Soares Sobrinho

Beilstein J. Nanotechnol. 2025, 16, 1751–1793, doi:10.3762/bjnano.16.122

• . Similar to CME, dynamin is responsible for vesicle formation; however, in this pathway, vesicles fuse with caveosomes, avoiding lysosomal degradation. This mechanism is the main advantage of this internalization pathway, making it a suitable alternative when NPs are sensitive to degradation. Albumin

• adjustments in the disassembly pH can optimize this mechanism, which must occur during the endo/lysosomal pathway to minimize cytotoxic effects. This highlights the significance of polymeric chemical functionality as a key factor for escape efficiency [85]. Once endocytosis followed by endosomal escape occurs

• . Diffusion-controlled release is directly influenced by the effective diffusion coefficient of the drug within the polymer matrix [10]. Erosion, as a release mechanism, involves the degradation of the polymer matrix, altering the nanostructure in two ways: surface and bulk erosion. In surface erosion, the

Advances of aptamers in esophageal cancer diagnosis, treatment and drug delivery

• Yang Fei,
• Hui Xu,
• Chunwei Zhang,
• Jingjing Wang and
• Yong Jin

Beilstein J. Nanotechnol. 2025, 16, 1734–1750, doi:10.3762/bjnano.16.121

• cells, slow down tumor growth and metastasis, and had no obvious toxicity to human normal esophageal epithelial cells. Cluster analysis showed that the mechanism of action of peptide 58 may be closely related to the inhibition of ESCC cell metabolism. However, pharmacokinetic data on peptide 58 remain

• azithromycin, but its effect in vivo is inferior. It is expected that ZY3A can be applied to clinical practice through optimizing drug administration strategies, such as combination of antibiotics and improvement of the aptamer structure. The mechanism of action of ZY3A may be to inhibit NF-κB pathway and MMP2

• frequently compromised by acquired drug resistance. Studies have revealed that one pivotal mechanism underlying this resistance involves the overexpression of P-gp on tumor cell surfaces [109]. Notably, DOX has been widely employed in drug delivery systems [110][111] due to its unique ability to

Beyond the bilayer: multilayered hygroscopic actuation in pine cone scales

• Kim Ulrich,
• Max David Mylo,
• Tom Masselter,
• Fabian Scheckenbach,
• Sophia Fischerbauer,
• Martin Nopens,
• Silja Flenner,
• Imke Greving,
• Linnea Hesse and
• Thomas Speck

Beilstein J. Nanotechnol. 2025, 16, 1695–1710, doi:10.3762/bjnano.16.119

• building parts [13], ceramic bilayer actuators [14], and 4D-printed weather-responsive façade shading elements [15]. The underlying principle in these biological examples is often compared to a thermally actuated “bimetal” mechanism [16][17]. The differential expansion or shrinkage of adjacent tissues

• humidity after a dry state ensures that the cone does not respond abruptly to transient increases in humidity, thereby stabilizing the seed dispersal process. A similar mechanism may apply to closed cones, where it has already been described that the initial opening is influenced by resin at the apophysis

• drawn by Horstmann et al. [21], who attributed the successive orchestration to the overlapping arrangement of scales and the constrained evaporation through the apophysis. This coordinated opening mechanism may facilitate seed dispersal since not all seeds are released at the same time. It also provides

Ambient pressure XPS at MAX IV

• Mattia Scardamaglia,
• Ulrike Küst,
• Alexander Klyushin,
• Rosemary Jones,
• Jan Knudsen,
• Robert Temperton,
• Andrey Shavorskiy and
• Esko Kokkonen

Beilstein J. Nanotechnol. 2025, 16, 1677–1694, doi:10.3762/bjnano.16.118

• , and the main Ni 2p peak broadens due to the emergence of an additional peak at 857.4 eV attributed to NiOOH. This indicates that photoexcitation triggers oxidation and structural changes, consistent with plasmon-driven electron excitation at the Ni/NiO interface. The authors propose a mechanism where

• beneath the native oxide layer, as reported in Figure 13. The Ni-Cr-Mo alloy exhibited activity towards the oxygen evolution reaction (OER), which is responsible for initiating passivity breakdown due to the dissolution of Mo in its Mo6+ state. This mechanism contrasts with the typical transpassive

• Attribution 4.0 International License, https://creativecommons.org/licenses/by/4.0). (a) Ni 2p XP spectra recorded at 1 mbar H2O pressure under dark (bottom spectra) and light illumination (top spectra) conditions. (b) Photocatalytic HER mechanism under light illumination 1 mbar H2O pressure. Figure 10 was

Prospects of nanotechnology and natural products for cancer and immunotherapy

• Jan Filipe Andrade Santos,
• Marcela Bernardes Brasileiro,
• Pamela Danielle Cavalcante Barreto,
• Ligiane Aranha Rocha and
• José Adão Carvalho Nascimento Júnior

Beilstein J. Nanotechnol. 2025, 16, 1644–1667, doi:10.3762/bjnano.16.116

• through their targeted mechanism [62]. Patent CN115252560 (2022) describes self-assembled nanoparticles composed of berberine, lonidamine, and gambogic acid in a 3:1:4 ratio, all acting as APIs, encapsulated with vitamin E polyethylene glycol succinate (VE-TPGS), an excipient, for stability. Berberis

Venom-loaded cationic-functionalized poly(lactic acid) nanoparticles for serum production against Tityus serrulatus scorpion

• Philippe de Castro Mesquita,
• Karla Samara Rocha Soares,
• Manoela Torres-Rêgo,
• Emanuell dos Santos-Silva,
• Mariana Farias Alves-Silva,
• Alianda Maira Cornélio,
• Matheus de Freitas Fernandes-Pedrosa and
• Arnóbio Antônio da Silva-Júnior

Beilstein J. Nanotechnol. 2025, 16, 1633–1643, doi:10.3762/bjnano.16.115

• controlled by diffusion mechanism was also measured. Finally, in vivo immunization in BALB/c mice showed superior efficacy of the T. serrulatus venom protein-loaded nanoparticles compared to the traditional aluminum hydroxide immunoadjuvant. Thus, the formulations shown are promising nanocarriers to be used

• the samples containing 0.5% and 1.0% of T. serrulatus venom, respectively. The mechanism of release of venom protein-loaded PLA nanoparticles profile was studied by applying different mathematical models to the experimental data. The data were subject to four different diffusion kinetic linear models

• : zero order, first order, Korsmeyer–Peppas, and parabolic diffusion (Table 2). The zero order, first order, and Korsmeyer–Peppas models exhibiting determination coefficient (r2) values demonstrate that the release mechanism cannot be explained by these models. The parabolic diffusion model better fitted

Nanotechnology-based approaches for the removal of microplastics from wastewater: a comprehensive review

• Nayanathara O Sanjeev,
• Manjunath Singanodi Vallabha and
• Rebekah Rubidha Lisha Rabi

Beilstein J. Nanotechnol. 2025, 16, 1607–1632, doi:10.3762/bjnano.16.114

• , and advanced membrane materials, exhibit unique properties such as high surface area, enhanced reactivity, and tunable surface chemistry, which offer promising avenues for the selective and efficient removal of MPs from water. This paper also explores the mechanism, performance and limitations of

• structure, and adjustable pore dimensions, designing a durable and compact MOF nanocomposite membrane could provide an effective strategy for MP filtration [116]. The mechanism involved in the removal of MPs using MOFs is represented in Figure 10. Gnanasekaran et al. [117] developed a novel composite

• fully explore and optimize MXenes’ capabilities, particularly for the removal of MPs from water. The mechanism involved in the removal of MPs using MXenes is shown in Figure 11. To develop lasting strategies for combating water pollution, integrating metals and metal oxides into membrane systems has