Quality by design optimization of microemulsions for topical delivery of Passiflora setacea seed oil

• Daniel T. Pereira,
• Douglas Dourado,
• Danielle T. Freire,
• Dayanne L. Porto,
• Cícero F. S. Aragão,
• Myla L. de Souza,
• Guilherme R. S. de Araujo,
• Ana Maria Costa,
• Wógenes N. Oliveira,
• Anne Sapin-Minet,
• Éverton N. Alencar and
• Eryvaldo Sócrates T. Egito

Beilstein J. Nanotechnol. 2025, 16, 2116–2131, doi:10.3762/bjnano.16.146

• other components such as NaCMC and vitamin E [44][45]. Surface tension The surface tension of the microemulsion was characterized through six replicates, yielding an average value of 40.27 ± 0.22 mN·m−1. Similar surface tension values have been reported for microemulsions in the literature [46][47

• ]. This range is considerably favorable for topical formulations, as lower surface tension enhances spreadability and promotes interaction with the stratum corneum and its lipidic barrier. Due to instrumental limitations associated with the high viscosity resulting from NaCMC addition, the surface tension

• of the MEgel could not be determined. However, NaCMC solutions exhibit negligible surface activity and typically maintain surface tension values close to that of water [48]. Rheological analysis Rheological profiling provides key insights into the behavior of formulations under applied stress or

Beyond the shell: exploring polymer–lipid interfaces in core–shell nanofibers to carry hyaluronic acid and β-caryophyllene

• Aline Tavares da Silva Barreto,
• Francisco Alexandrino-Júnior,
• Bráulio Soares Arcanjo,
• Paulo Henrique de Souza Picciani and
• Kattya Gyselle de Holanda e Silva

Beilstein J. Nanotechnol. 2025, 16, 2015–2033, doi:10.3762/bjnano.16.139

• concentration, surface tension, conductivity, and solvent volatility, alongside careful consideration of electrospinning conditions, such as temperature and humidity [18][19]. The polymer selection of nanofibers intended for biomedical applications must prioritize not only mechanical strength, controlled

Laser ablation in liquids for shape-tailored synthesis of nanomaterials: status and challenges

• Natalie Tarasenka

Beilstein J. Nanotechnol. 2025, 16, 1963–1997, doi:10.3762/bjnano.16.137

Multifunctional anionic nanoemulsion with linseed oil and lecithin: a preliminary approach for dry eye disease

• Niédja Fittipaldi Vasconcelos,
• Almerinda Agrelli,
• Rayane Cristine Santos da Silva,
• Carina Lucena Mendes-Marques,
• Isabel Renata de Souza Arruda,
• Priscilla Stela Santana de Oliveira,
• Mércia Liane de Oliveira and
• Giovanna Machado

Beilstein J. Nanotechnol. 2025, 16, 1711–1733, doi:10.3762/bjnano.16.120

• suggests that the lecithin content in the O/W(L-1%) and O/W(L-2%) pre-formulations is insufficient to effectively reduce surface tension, resulting in incomplete droplet coverage and subsequent coalescence. As the lecithin concentration in the pre-formulations was increased, the hydrodynamic diameter of

• surface tension by fully covering the interfacial surface area, thereby stabilizing the emulsion structure [80][81]. Among the pre-formulations, O/W(L-3%) demonstrated optimal performance, with a hydrodynamic diameter of approximately 300 nm and a PdI value of 0.252. This monomodal intensity distribution

Ambient pressure XPS at MAX IV

• Mattia Scardamaglia,
• Ulrike Küst,
• Alexander Klyushin,
• Rosemary Jones,
• Jan Knudsen,
• Robert Temperton,
• Andrey Shavorskiy and
• Esko Kokkonen

Beilstein J. Nanotechnol. 2025, 16, 1677–1694, doi:10.3762/bjnano.16.118

• meniscus must be thin enough to allow photoelectrons to escape, yet thick enough to maintain electrical contact. The meniscus thickness depends on factors such as the wetting properties of the WE, liquid viscosity, surface tension, and pulling speed. This geometry enables true operando studies of solid

Influence of laser beam profile on morphology and optical properties of silicon nanoparticles formed by laser ablation in liquid

• Natalie Tarasenka,
• Vladislav Kornev,
• Alena Nevar and
• Nikolai Tarasenko

Beilstein J. Nanotechnol. 2025, 16, 1533–1544, doi:10.3762/bjnano.16.108

• influence CB evolution. These parameters strongly affect size and morphology of the forming NPs. In general, the dynamics of the CBs [38] is described by a modified Rayleigh–Plesset equation [39], which considers the pressure and size of CBs depending on parameters of both liquid (surface tension, density

Laser processing in liquids: insights into nanocolloid generation and thin film integration for energy, photonic, and sensing applications

• Akshana Parameswaran Sreekala,
• Pooja Raveendran Nair,
• Jithin Kundalam Kadavath,
• Bindu Krishnan,
• David Avellaneda Avellaneda,
• M. R. Anantharaman and
• Sadasivan Shaji

Beilstein J. Nanotechnol. 2025, 16, 1428–1498, doi:10.3762/bjnano.16.104

• volume of precursor solution, characterized by low surface tension, is released from a capillary tube either by dripping with negligible initial velocity or by injection with an initial velocity. The droplet is then directed toward the substrate, where the ultrasonic vibration aids in controlling the

Multifunctional properties of bio-poly(butylene succinate) reinforced with multiwalled carbon nanotubes

• Volodymyr Krasinskyi,
• Krzysztof Bajer,
• Ludmila Dulebova,
• Nickolas Polychronopoulos,
• Oksana Krasinska and
• Daniel Kaczor

Beilstein J. Nanotechnol. 2025, 16, 1014–1024, doi:10.3762/bjnano.16.76

• water absorption (n) was measured following ISO 62:2008 “Plastics – Determination of Water Absorption”, using film samples of a square shape (50 × 50 mm2) with a thickness of 350 µm. The surface tension or wettability (σ) of the films was measured according to ISO 8296:2003 “Plastics – Film and Sheeting

Ar⁺ implantation-induced tailoring of RF-sputtered ZnO films: structural, morphological, and optical properties

• Manu Bura,
• Divya Gupta,
• Arun Kumar and
• Sanjeev Aggarwal

Beilstein J. Nanotechnol. 2025, 16, 872–886, doi:10.3762/bjnano.16.66

• surface relaxation process, which leads to the smoothening of the surface and is also mentioned as negative surface tension by others [32][33]. This process causes the breaking of larger structures into smaller ones. Thus, one can tune the surface morphology of films using an inert ion beam through a

Aprepitant-loaded solid lipid nanoparticles: a novel approach to enhance oral bioavailability

• Mazhar Hussain,
• Muhammad Farooq,
• Muhammad Asad Saeed,
• Muhammad Ijaz,
• Sherjeel Adnan,
• Zeeshan Masood,
• Muhammad Waqas,
• Wafa Ishaq and
• Nabeela Ameer

Beilstein J. Nanotechnol. 2025, 16, 652–663, doi:10.3762/bjnano.16.50

• β-CD concentration converted crystalline entrapped APT into an amorphous state, decreasing surface tension and promoting the solubility profile [14]. A similar behavior was observed for the poloxamer 407 samples with solubilities in the order of APT-PX-NP5 > APT-PX-NP6 > APT-PX-NP7 > APT-PX-NP8 due

Polyurethane/silk fibroin-based electrospun membranes for wound healing and skin substitute applications

• Iqra Zainab,
• Zohra Naseem,
• Syeda Rubab Batool,
• Muhammad Waqas,
• Ahsan Nazir and
• Muhammad Anwaar Nazeer

Beilstein J. Nanotechnol. 2025, 16, 591–612, doi:10.3762/bjnano.16.46

• through a capillary, and a high voltage is applied to charge the solution’s particles, which produces an attractive force [54]. When the solution’s surface tension is overcome at a critical voltage, a jet shoots out of the capillary’s tip toward a grounded collector (Figure 2A) [55]. The morphology of

Enhancing mechanical properties of chitosan/PVA electrospun nanofibers: a comprehensive review

• Nur Areisman Mohd Salleh,
• Amalina Muhammad Afifi,
• Fathiah Mohamed Zuki and
• Hanna Sofia SalehHudin

Beilstein J. Nanotechnol. 2025, 16, 286–307, doi:10.3762/bjnano.16.22

• , including irregular fluid jet movement, variations in surface tension, and sensitivity to external parameters such as temperature, humidity, and airflow. These factors can disrupt the uniformity of the fiber formation. When the fiber jets are drawn in the direction of the electric field force, the polymer

• ]. Electrospinning involves applying a high voltage to a polymer solution delivered through a nozzle or capillary [71]. The electrostatic charge builds up at the tip of the droplet, and when the repulsive force of the charges overcomes the droplet’s surface tension, a cone-like jet, known as the Taylor cone, forms

Effect of radiation-induced vacancy saturation on the first-order phase transformation in nanoparticles: insights from a model

• Aram Shirinyan and
• Yuriy Bilogorodskyy

Beilstein J. Nanotechnol. 2024, 15, 1453–1472, doi:10.3762/bjnano.15.117

• nanomaterials with phase change and reduction in surface tension serve as suitable systems for elucidation and comparison. In summary, there is a competition among various energetic factors influencing phase stability and transformations in HDCMs during irradiation. These factors include (i) the bulk

Beyond biomimicry – next generation applications of bioinspired adhesives from microfluidics to composites

• Dan Sameoto

Beilstein J. Nanotechnol. 2024, 15, 965–976, doi:10.3762/bjnano.15.79

• the channels but also directed the liquid metal flow via Laplace barriers within the channels, offering a mechanism by which we could precisely control the filling of a liquid with very high surface tension [36] (Figure 5). Additionally, small subfeatures within the microfluidic channels could allow

• non-planar surfaces, bonded to microelectromechanical systems (MEMS), and their use in droplet generation with oil and water. Laplace barriers within geckofluidic channels have directed room-temperature liquid metals (eutectic gallium–indium) with extremely high surface tension to properly fill

Therapeutic effect of F127-folate@PLGA/CHL/IR780 nanoparticles on folate receptor-expressing cancer cells

• Thi Ngoc Han Pham,
• Phuong-Thao Dang-Luong,
• Hong-Phuc Nguyen,
• Loc Le-Tuan,
• Xuan Thang Cao,
• Thanh-Danh Nguyen,
• Vy Tran Anh and
• Hieu Vu_Quang

Beilstein J. Nanotechnol. 2024, 15, 954–964, doi:10.3762/bjnano.15.78

• pluronic F127 (F127), can be used in the water phase to lower the surface tension of the organic phase and to produce the nanoemulsion during the homogenization process [5][6][7]. F127 is a copolymer made up of blocks of poly(ethylene oxide)–poly(propylene oxide)–poly(ethylene oxide), PEO100–PPO65–PEO100

Electrospun nanofibers: building blocks for the repair of bone tissue

• Tuğrul Mert Serim,
• Gülin Amasya,
• Tuğba Eren-Böncü,
• Ceyda Tuba Şengel-Türk and
• Ayşe Nurten Özdemir

Beilstein J. Nanotechnol. 2024, 15, 941–953, doi:10.3762/bjnano.15.77

• , concentration and molecular weight of the polymer, solvent or solvent mixture, surface tension, conductivity, dielectric constant, and environmental parameters are parameters that must be optimized in the electrospinning process. Voltage Voltage is the parameter that most affects the shape of the droplet from

• and causes a change in viscosity, surface tension, and electrical conductivity of the polymer liquid [54][65]. The evaporation rate of the solvent is an extremely important parameter. In an ideal production process, the solvent must be completely evaporated before the jet reaches the collector of the

• , ethanol, formic acid, and tetrahydrofuran. Depending on the polymer type or the hybrid polymer composition, these organic solvents can be used alone or applied as mixtures in order to obtain suitable solution properties [67]. Surface tension The surface tension of the polymer liquid is important for the

The effect of age on the attachment ability of stick insects (Phasmatodea)

• Marie Grote,
• Stanislav N. Gorb and
• Thies H. Büscher

Beilstein J. Nanotechnol. 2024, 15, 867–883, doi:10.3762/bjnano.15.72

• -Aldrich, St. Louis, USA) for 30 min to reduce surface tension and enable proper glycerin coating. Afterwards, samples were rinsed three times in glycerin and then fully submerged in glycerin and covered with a high-precision cover slip (Carl Zeiss Microscopy GmbH, Jena, Germany). Images were taken using a

Laser synthesis of nanoparticles in organic solvents – products, reactions, and perspectives

• Theo Fromme,
• Sven Reichenberger,
• Katharine M. Tibbetts and
• Stephan Barcikowski

Beilstein J. Nanotechnol. 2024, 15, 638–663, doi:10.3762/bjnano.15.54

• Equation 2. This yielded the carbon solubility S as a function of the particle radius r via the solubility in the bulk state S0, the surface tension σ, the volume of a metal molecule V, the Boltzmann’s constant k and the melting temperature of the bulk state T. When the Au particle size exceeds a threshold

Investigating ripple pattern formation and damage profiles in Si and Ge induced by 100 keV Ar⁺ ion beam: a comparative study

• Indra Sulania,
• Harpreet Sondhi,
• Tanuj Kumar,
• Sunil Ojha,
• G R Umapathy,
• Ambuj Mishra,
• Ambuj Tripathi,
• Richa Krishna,
• Devesh Kumar Avasthi and
• Yogendra Kumar Mishra

Beilstein J. Nanotechnol. 2024, 15, 367–375, doi:10.3762/bjnano.15.33

• Harper [31] based on morphological effects of IBS. The height h(x, y, t) of the sputtered surface can be described by a linear equation (Equation 1): where ν0 is the constant erosion velocity, ν is the effective surface tension, and D denotes the surface diffusion which is activated by different physical

Batch preparation of nanofibers containing nanoparticles by an electrospinning device with multiple air inlets

• Dong Wei,
• Chengwei Ye,
• Adnan Ahmed and
• Lan Xu

Beilstein J. Nanotechnol. 2023, 14, 141–150, doi:10.3762/bjnano.14.15

• force (Ph) caused by the fluctuation height of spinning solution, surface tension (Ps) of the spinning solution, and electric field force (PE) produced by the applied voltage. These forces determine whether a jet could be formed at point A. The polymer fluid surface tension would make the liquid surface

• density of spinning solution (kg/m3), g is the gravitational acceleration (m/s2), h is the fluctuation height of the polymer spinning solution (m), γ is the surface tension coefficient of the spinning solution (N/m), ε0 is vacuum dielectric constant, E0 is the edge electric field intensity (V/m), Ep is

• surface tension (Ps), unstable fluctuation on the free surface of solution easily occurs, thus significantly increasing the probability of multijet formation [25][26]. In order to study further the electric field forces on the spinning solution surface under different voltages, the electric field

Frequency-dependent nanomechanical profiling for medical diagnosis

• Santiago D. Solares and
• Alexander X. Cartagena-Rivera

Beilstein J. Nanotechnol. 2022, 13, 1483–1489, doi:10.3762/bjnano.13.122

• property approximations, for example in the study of arterial degeneration [34][35]. Besides the above frequency-dependent representation, other important measurements can be recorded, such as general topography and morphology, cell or tissue adhesive properties, internal hydrostatic pressure, and surface

• tension. These additional multidimensional biophysical parameters could be inferred from the AFM spectroscopy data as well, and could be correlated with the frequency-dependent nanomechanical parameters previously described to provide richer mechanistic knowledge of the genesis of a complex disease and

Dry under water: air retaining properties of large-scale elastomer foils covered with mushroom-shaped surface microstructures

• Matthias Mail,
• Stefan Walheim,
• Thomas Schimmel,
• Wilhelm Barthlott,
• Stanislav N. Gorb and
• Lars Heepe

Beilstein J. Nanotechnol. 2022, 13, 1370–1379, doi:10.3762/bjnano.13.113

• the surface tension of water, cos θ is the water contact angle of poly(vinylsiloxane) which was assumed to be 95°, and ρw = 997 kg/m3 the density of water, and g the gravitational acceleration. The reduced bubble lifetime for h > hmax whereas Vi is the initial volume of the air layer, with Ai the

Straight roads into nowhere – obvious and not-so-obvious biological models for ferrophobic surfaces

• Wilfried Konrad,
• Christoph Neinhuis and
• Anita Roth-Nebelsick

Beilstein J. Nanotechnol. 2022, 13, 1345–1360, doi:10.3762/bjnano.13.111

• so far as air layers are observed to form in liquids of diverse chemical compositions, including organic solvents and oils, which show a wide variety of surface tension values and contact angles with respect to the skin [3][21]. This “omniphobic” property allows the Collembola to live in areas of

• soil or water bodies that contain a high concentration of organic liquids that are, for instance, the product of decay processes and may reduce considerably the surface tension of water. In addition, the plastron is able to withstand external pressure exceeding 0.4 MPa. The air, which is not able to

• interface are in equilibrium, the Young–Laplace equation [50] states that the difference between liquid pressure pl and gas pressure pg is counterbalanced by the surface tension term 2σH, according to σ denotes the surface tension and H the mean curvature of the gas/liquid interface. If pl and pg are

Temperature and chemical effects on the interfacial energy between a Ga–In–Sn eutectic liquid alloy and nanoscopic asperities

• Yujin Han,
• Pierre-Marie Thebault,
• Corentin Audes,
• Xuelin Wang,
• Haiwoong Park,
• Jian-Zhong Jiang and
• Arnaud Caron

Beilstein J. Nanotechnol. 2022, 13, 817–827, doi:10.3762/bjnano.13.72

• liquid metals strongly depend on their surface and interfacial properties. The surface tension of room-temperature-liquid Ga-based alloys has been reported to be lowered by a thin surface oxide layer [8]. In [9], the authors electrochemically controlled the growth and removal of gallium oxide to tune the

• surface tension of liquid gallium. Oxygen is a surface-active substance whose effect on surface tension has been investigated for various liquid metals [10]. In metallic alloys, surface segregation has also been observed, where an element with a higher oxygen affinity enriches at the surface to form an

• of the tips toward the liquid sample. Table 2 indicates the average values and ranges of γm and κ for the three different tip chemistries. Specifically, we find = 230 mN/m and = 3 mN/Km for SiOx, = 110 mN/m and = 2 mN/Km for Au, and = 68 mN/m and = 0.8 mN/Km for PtSi. The surface tension of Ga

Systematic studies into uniform synthetic protein nanoparticles

• Nahal Habibi,
• Ava Mauser,
• Jeffery E. Raymond and
• Joerg Lahann

Beilstein J. Nanotechnol. 2022, 13, 274–283, doi:10.3762/bjnano.13.22

• used for all jetting experiments. This inclusion of ethanol decreased the dielectric constant and surface tension of the solution. The exception was insulin- and mucin-based SPNPs, which were manufactured as described in the Materials section. Furthermore, a homobifunctional amine-reactive macromer