Functionalized polystyrene nanoparticles as a platform for studying bio–nano interactions

• Cornelia Loos,
• Tatiana Syrovets,
• Anna Musyanovych,
• Volker Mailänder,
• Katharina Landfester,
• G. Ulrich Nienhaus and
• Thomas Simmet

Beilstein J. Nanotechnol. 2014, 5, 2403–2412, doi:10.3762/bjnano.5.250

• CellMask (red). Adapted with permission from [43]. Copyright 2011 American Chemical Society. Uptake kinetics and subcellular localization of carboxyl- and amino-functionalized polystyrene nanoparticles by THP-1 (A), differentiated THP-1 cells (B), and human macrophages (C). The cells were incubated with PS

Nanoparticle interactions with live cells: Quantitative fluorescence microscopy of nanoparticle size effects

• Li Shang,
• Karin Nienhaus,
• Xiue Jiang,
• Linxiao Yang,
• Katharina Landfester,
• Volker Mailänder,
• Thomas Simmet and
• G. Ulrich Nienhaus

Beilstein J. Nanotechnol. 2014, 5, 2388–2397, doi:10.3762/bjnano.5.248

• reproduced with permission from [32]. Copyright 2011 Royal Society of Chemistry. Images in panels d–f were reproduced with permission from [33]. Copyright 2010 American Chemical Society. Schematic depiction of the interplay between membrane receptors (depicted as cups) and NP surface ligands (depicted as

Inorganic Janus particles for biomedical applications

• Isabel Schick,
• Steffen Lorenz,
• Dominik Gehrig,
• Stefan Tenzer,
• Wiebke Storck,
• Karl Fischer,
• Dennis Strand,
• Frédéric Laquai and
• Wolfgang Tremel

Beilstein J. Nanotechnol. 2014, 5, 2346–2362, doi:10.3762/bjnano.5.244

• formation of Cu@Fe3O4 heterodimers with different morphologies based on the use of solvents of various polarity (top) and corresponding (HR-)TEM images of (a, b) cube-shape, (c, d) cloverleaf-shape Cu@Fe3O4 heterodimerparticles (bottom). Reproduced with permission from [57]. Copyright 2011 The Royal Society

• of Chemistry. Synthetic protocol of the synthesis of Co@Fe2O3 heterodimer and phase pure CoFe2O4 nanoparticles (top) and corresponding (HR-)TEM images of (a,b) heterodimer particles and (c,d) isotropic CoFe2O4 nanoparticles. Reproduced with permission from [59]. Copyright 2011 The Royal Society of

Liquid-phase exfoliated graphene: functionalization, characterization, and applications

• Mildred Quintana,
• Jesús Iván Tapia and
• Maurizio Prato

Beilstein J. Nanotechnol. 2014, 5, 2328–2338, doi:10.3762/bjnano.5.242

• 2010 Wiley-VCH. TEM and AFM micrographs after the addition of Au NPs for the identification of reactive sites against 1,3-dipolar cycloaddition (a–c) and amidation reaction on carboxylic groups created during the sonication process (d–f). Reproduced with permission from [42], copyright 2011 The Royal

Localized surface plasmon resonances in nanostructures to enhance nonlinear vibrational spectroscopies: towards an astonishing molecular sensitivity

• Dan Lis and
• Francesca Cecchet

Beilstein J. Nanotechnol. 2014, 5, 2275–2292, doi:10.3762/bjnano.5.237

• (Figure 7b,c). In 2011, Lis et al. reported the enhancement of an alkanethiol SAM on randomly distributed gold nanopillars vertically-aligned on either a flat platinum or gold surface (Figure 8a) [77]. The authors achieved a selective excitation of the nanopillar LSPR modes by tuning the visible frequency

• . showed in 2011 that SE-CARS could be used to obtain large scale images of tissues, for diagnostic purposes [82]. The authors demonstrated that, similarly to immunohistochemistry (IHC) that labels antibodies with dyes or enzymes to image the tissue with conventional light microscope, antibody-labeled

• , which often reduces image contrast in common immunofluorescence images. These properties promoted SE-CARS and CARS microscopy as a new tool for biomedical analysis. Still in 2011, Namboodiri et al. investigated the SERS and SE-CARS contribution from a mixture of pyridine molecules and silver colloids

Hybrid spin-crossover nanostructures

• Carlos M. Quintero,
• Gautier Félix,
• Iurii Suleimanov,
• José Sánchez Costa,
• Gábor Molnár,
• Lionel Salmon,
• William Nicolazzi and
• Azzedine Bousseksou

Beilstein J. Nanotechnol. 2014, 5, 2230–2239, doi:10.3762/bjnano.5.232

• SCO systems. Synthesis route and schematic representation of the luminescent, SCO, SiO2 nanoparticles. Reproduced with permission from [21], copyright 2011 Wiley-VCH. a) Schematic overview of the formation of the nanocomposite, gold-decorated SCO–SiO2 nanoparticles. b) TEM and c) STEM–EDX images of

• [27], copyright 2011 American Chemical Society. a) Architecture of the OLED device constructed by Matsuda et al. [28]. b) A schematic representation of the mechanism proposed for the EL, on/off switching, based on an energy level diagram of a device using Chl a and [Fe(dpp)2](BF)4. c) Energy level

Electrical contacts to individual SWCNTs: A review

• Wei Liu,
• Christofer Hierold and
• Miroslav Haluska

Beilstein J. Nanotechnol. 2014, 5, 2202–2215, doi:10.3762/bjnano.5.229

• contact (using Pd as the contact metal) by pulsed current. Figure reprinted with permission from (a) [70] copyright 2011 Author(s) and (b) [50] copyright 1999 The American Association for the Advancement of Science. Work function of various metals [63] (units: eV). Different annealing conditions for

Nanometer-resolved mechanical properties around GaN crystal surface steps

• Jörg Buchwald,
• Marina Sarmanova,
• Bernd Rauschenbach and
• Stefan G. Mayr

Beilstein J. Nanotechnol. 2014, 5, 2164–2170, doi:10.3762/bjnano.5.225

• the German Excellence Initiative. A grant of computing time by the Center for Information Services and High Performance Computing (ZIH), TU Dresden, is gratefully acknowledged. This work is funded by the SAW award of the German Leibniz Association (SAW-2011-IOM-2).

Biopolymer colloids for controlling and templating inorganic synthesis

• Laura C. Preiss,
• Katharina Landfester and
• Rafael Muñoz-Espí

Beilstein J. Nanotechnol. 2014, 5, 2129–2138, doi:10.3762/bjnano.5.222

• with (3-aminopropyl)trimethoxysilane (APTMS), (b) DNA deposition on the cationic particle surface, (c) CdS precipitation, and (d) dissolution of the SiO2 core to form hollow structures. Reprinted with permission from [52]. Copyright 2011 American Chemical Society. Siloxan polymerization on chitosan

Carbon nano-onions (multi-layer fullerenes): chemistry and applications

• Juergen Bartelmess and
• Silvia Giordani

Beilstein J. Nanotechnol. 2014, 5, 1980–1998, doi:10.3762/bjnano.5.207

• research on carbon nanostructures. Biological and environmental applications Biological imaging: In contrast to other carbon nanomaterials such as CNTs [52] or carbon quantum dots [53], CNOs have not been widely employed in biological marking, yet. A first report was published in 2011 by Sarkar et al. by

• 2011 John Wiley and Sons. High-resolution TEM images of pristine CNOs (left). AFM topographs of pristine CNOs deposited on mica (center). Confocal microscopy of C57BL/6 BMDCs incubated in the presence of fluorescein-labelled-CNOs and stained with wheat germ agglutinin-Alexa Fluor594 (red), fluorescein

Spin annihilations of and spin sifters for transverse electric and transverse magnetic waves in co- and counter-rotations

• Hyoung-In Lee and
• Jinsik Mok

Beilstein J. Nanotechnol. 2014, 5, 1887–1898, doi:10.3762/bjnano.5.199

• Basic Science Research Program through the National Research Foundation (NRF) of Korea funded by the Ministry of Education, Science and Technology (Grant Number: 2011-0023612).

Cathode lens spectromicroscopy: methodology and applications

• T. O. Menteş,
• G. Zamborlini,
• A. Sala and
• A. Locatelli

Beilstein J. Nanotechnol. 2014, 5, 1873–1886, doi:10.3762/bjnano.5.198

• in (a). a) LEEM images (2 μm diameter) of monolayer Pd stripes on W(110). The lower left panel shows Pd on a clean substrate, whereas the other two panels display the progressive change in pattern anisotropy upon addition of 0.1 ML and 0.33 ML oxygen. (Reprinted from [69]. Copyright 2011 IOP

Electronic and electrochemical doping of graphene by surface adsorbates

• Hugo Pinto and
• Alexander Markevich

Beilstein J. Nanotechnol. 2014, 5, 1842–1848, doi:10.3762/bjnano.5.195

• ]. Copyright 2011 Elsevier. Acknowledgements The authors would like to thank R. Jones, J. P. Goss, D. W. Palmer and S. Öberg for helpful discussions and their important contribution into some of the theoretical work discussed in the present article. The financial support from the COST action MP0901 “NanoTP

A reproducible number-based sizing method for pigment-grade titanium dioxide

• Ralf Theissmann,
• Manfred Kluwig and
• Thomas Koch

Beilstein J. Nanotechnol. 2014, 5, 1815–1822, doi:10.3762/bjnano.5.192

• 2011 on the definition of particulate nanomaterial, or for other forthcoming regulations in the future. Experimental The experimental procedures described below are in full agreement with the practical guide for particle size characterization published by NIST [22]. Sample preparation A well-prepared

Silicon and germanium nanocrystals: properties and characterization

• Ivana Capan,
• Alexandra Carvalho and
• José Coutinho

Beilstein J. Nanotechnol. 2014, 5, 1787–1794, doi:10.3762/bjnano.5.189

• , the relative localization on the molecule (negative values) and on the NC (positive values). Reprinted with permission from [20]. Copyright 2011 The American Physical Society. Acknowledgements The authors acknowledge financial support from the COST MP0901-NanoTP Action. JC thanks the FCT through

In vitro and in vivo interactions of selected nanoparticles with rodent serum proteins and their consequences in biokinetics

• Wolfgang G. Kreyling,
• Stefanie Fertsch-Gapp,
• Martin Schäffler,
• Blair D. Johnston,
• Nadine Haberl,
• Christian Pfeiffer,
• Jörg Diendorf,
• Carsten Schleh,
• Stephanie Hirn,
• Manuela Semmler-Behnke,
• Matthias Epple and
• Wolfgang J. Parak

Beilstein J. Nanotechnol. 2014, 5, 1699–1711, doi:10.3762/bjnano.5.180

• regression forced through the coordinate origin with the slope representing the binding index (BI). BSA binds with a much higher BI to hydrophobic, neutrally charged PS-Plain NP than the two other hydrophilic PS-NP. Reproduced with permission from [5]. Copyright 2011 Informa Plc. The size-selective

• < 0.05 (*), p < 0.01 (**), p < 0.001 (***). Mass and surface area related to binding indices BI of the NP to the three different proteins, albumin, transferrin and apolipoprotein A-1. Reproduced with permission from [5]. Copyright 2011 Informa Plc. Diameter refers to the geometrical diameter as observed

Non-covalent and reversible functionalization of carbon nanotubes

• Antonello Di Crescenzo,
• Valeria Ettorre and
• Antonella Fontana

Beilstein J. Nanotechnol. 2014, 5, 1675–1690, doi:10.3762/bjnano.5.178

• fractions excited at 785 nm. Reprinted with permission from [62]. Copyright 2011, Wiley VCH. Schematic illustration of the different possible organizations of surfactant molecules on the surface of a CNT. Upper images refer to lateral projections; lower images refer to cross sections. Representative

Precise quantification of silica and ceria nanoparticle uptake revealed by 3D fluorescence microscopy

• Adriano A. Torrano and
• Christoph Bräuchle

Beilstein J. Nanotechnol. 2014, 5, 1616–1624, doi:10.3762/bjnano.5.173

• of nanoparticles designed for medical applications. Experimental Nanoparticle characterization Nanoparticle size was determined by transmission electron microscopy (TEM). TEM micrographs were acquired by a JEM 2011 (JEOL, Japan) transmission electron microscope. The nanoparticle dispersion was

Growth evolution and phase transition from chalcocite to digenite in nanocrystalline copper sulfide: Morphological, optical and electrical properties

• Priscilla Vasthi Quintana-Ramirez,
• Ma. Concepción Arenas-Arrocena,
• José Santos-Cruz,
• Marina Vega-González,
• Omar Martínez-Alvarez,
• Víctor Manuel Castaño-Meneses,
• Laura Susana Acosta-Torres and
• Javier de la Fuente-Hernández

Beilstein J. Nanotechnol. 2014, 5, 1542–1552, doi:10.3762/bjnano.5.166

• Avanzada, Universidad Nacional Autónoma de México, 76230, Querétaro, México Escuela Nacional de Estudios Superiores Unidad León, UNAM, Boulevard UNAM No. 2011 Predio el Saucillo y el Potrero, 36969, León Guanajuato, México Facultad de Química, Materiales Universidad Autónoma de Querétaro, 76010, Querétaro

In vitro interaction of colloidal nanoparticles with mammalian cells: What have we learned thus far?

• Moritz Nazarenus,
• Qian Zhang,
• Mahmoud G. Soliman,
• Pablo del Pino,
• Beatriz Pelaz,
• Susana Carregal-Romero,
• Joanna Rejman,
• Barbara Rothen-Rutishauser,
• Martin J. D. Clift,
• Reinhard Zellner,
• G. Ulrich Nienhaus,
• James B. Delehanty,
• Igor L. Medintz and
• Wolfgang J. Parak

Beilstein J. Nanotechnol. 2014, 5, 1477–1490, doi:10.3762/bjnano.5.161

• their composition, functionality, and fields of application. Reproduced with permission from [11]. Copyright (2011) American Chemical Society. Hybrid nature of typical NPs, comprising different structural compartments. Reproduced with permission from [13]. Copyright (2013) American Chemical Society

• . Scheme depicting the different mechanisms of cellular endocytosis. Reproduced with permission from [41]. Copyright (2011) Elsevier. Fluorescence microscopy image showing the granular structure of internalized NPs inside A549 lung cancer cells (two types of iron oxide NPs with different surface chemistry

Magnesium batteries: Current state of the art, issues and future perspectives

• Rana Mohtadi and
• Fuminori Mizuno

Beilstein J. Nanotechnol. 2014, 5, 1291–1311, doi:10.3762/bjnano.5.143

Sublattice asymmetry of impurity doping in graphene: A review

• James A. Lawlor and
• Mauro S. Ferreira

Beilstein J. Nanotechnol. 2014, 5, 1210–1217, doi:10.3762/bjnano.5.133

• properties. The electron wavefunctions in such a system are shown to mainly exist on the sublattice without dopants and can travel almost unhindered [36][37], which is very promising for overcoming the scattering problem. It was not until 2011 that a viable experimental approach was found by Zhao et al. [38

Model systems for studying cell adhesion and biomimetic actin networks

• Dorothea Brüggemann,
• Johannes P. Frohnmayer and
• Joachim P. Spatz

Beilstein J. Nanotechnol. 2014, 5, 1193–1202, doi:10.3762/bjnano.5.131

• represent 10 μm. (Adapted with permission from [72]. Copyright (2011) American Chemical Society.) Transformed liposomes observed by dark-field microscopy in the presence of talin. Liposomes used were prepared from phosphatidylethanolamine and phosphatidylglycerol (1:1, mol:mol). (A) Closed spherical

Organic and inorganic–organic thin film structures by molecular layer deposition: A review

• Pia Sundberg and
• Maarit Karppinen

Beilstein J. Nanotechnol. 2014, 5, 1104–1136, doi:10.3762/bjnano.5.123

The study of surface wetting, nanobubbles and boundary slip with an applied voltage: A review

• Yunlu Pan,
• Bharat Bhushan and
• Xuezeng Zhao

Beilstein J. Nanotechnol. 2014, 5, 1042–1065, doi:10.3762/bjnano.5.117