This search combines search strings from the content search (i.e. "Full Text", "Author", "Title", "Abstract", or "Keywords") with "Article Type" and "Publication Date Range" using the AND operator.
Beilstein J. Org. Chem. 2026, 22, 763–770, doi:10.3762/bjoc.22.58
Graphical Abstract
Figure 1: Examples of biologically active imidazo[1,2-a]pyridines.
Figure 2: Compounds envisaged for synthesis.
Scheme 1: Preparation of methyl esters 13 versus unsubstituted derivatives 12 under various conditions. Metho...
Scheme 2: Ester hydrolysis and in situ decarboxylation.
Figure 3: Previously reported 3-amino-2-carboxylic acid derivatives.
Scheme 3: Ester reduction to the corresponding alcohols. Reaction yields are provided in parentheses.
Figure 4: Single crystal X-ray structure of 18a. ORTEP diagram drawn at 50% probability level.
Scheme 4: Oxidative ring-opening with loss of one carbon atom. Yields are provided in parentheses.
Scheme 5: Oxidative conditions applied to decarboxylated compound 12b.
Figure 5: Different oxidative cleavage products obtained under different conditions.
Scheme 6: Unexpected aldehyde formation from tosylation reaction.
Scheme 7: Kornblum oxidation to give imidazo[1,2-a]pyridine-2-carbaldehydes 20. Yield over two steps from the...
Scheme 8: Reductive amination reactions to give target molecules 8.
Beilstein J. Org. Chem. 2021, 17, 2340–2347, doi:10.3762/bjoc.17.152
Figure 1: Biologically active phenanthridines.
Figure 2: Synthetic routes to phenanthridines via iminyl radicals.
Scheme 1: Previous unexpected synthesis of the phenanthridine framework.
Scheme 2: Synthesis of biaryl benzaldehydes.
Scheme 3: Synthesis of biaryl oximes.
Scheme 4: Synthesis of phenanthridines. Reagents and conditions (i) UV irradiation (450 W medium pressure Hg ...
Figure 3: Two possible mechanistic routes and intermediates in the synthesis of phenanthridines.
Scheme 5: Synthesis of trisphaeridine. Reagents and conditions (i) cat. Pd(PPh3)4, aq Na2CO3, DME, reflux, Ar...
Beilstein J. Org. Chem. 2021, 17, 1440–1446, doi:10.3762/bjoc.17.99
Figure 1: Structure of pavettamine 1 and its enantiomer 2.
Scheme 1: Established route for the synthesis of intermediate 4 [1].
Scheme 2: Alternative route. Reaction conditions: a) TrCl, pyridine, rt, overnight, 100%; b) DMAP, imidazole,...
Figure 2: Crystal structure of compound 9.
Scheme 3: Sequence showing the source of compound 9.
Scheme 4: Stereoselective reduction of intermediate 8 as key step towards intermediate 4. Reaction conditions...
Figure 3: Single crystal X-ray structure of compound 4.
Scheme 5: Synthesis of the C5 fragments from intermediate 4. Reaction conditions: a) i) TFAA, collidine, 0 °C...
Scheme 6: Synthesis of ent-pavettamine as the TFA salt 28. Reaction conditions: a) IBX, DMSO, rt, overnight, ...