2 article(s) from Khunnawutmanotham, Nisachon
- Full Research Paper
- Published 02 Oct 2018
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Graphical Abstract
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Figure 1: Design of the target compounds.
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Scheme 1: Synthesis of 3-aminocoumarin-N-benzylpyridinium salts.
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Figure 2: Docked conformations of donepezil (ball-and-stick model; pink), compounds 9a, 9b, 9e, 9h, and 9i (s...
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Figure 3: Binding interactions in the rhAChE binding pocket with (a) 4a, (b) 9a, (c) 9b, (d) 9e, (e) 9h, (f) ...
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- Full Research Paper
- Published 22 Jul 2009
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Graphical Abstract
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Figure 1: Structure of nevirapine (1).
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Figure 2: Structures of dipyridodiazepinone derivatives with promising anti-HIV activity.
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Scheme 1: Reagents and conditions: (a) EtNH2, 120 °C, 4 h, 99% (b) i) (COCl)2, benzene, DMF, rt, 1 h; ii) ami...
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Scheme 2: Reagents and conditions: (a) Br2, HOAc, KOAc, rt, 1 h; (b) NaHMDS, pyridine, 90 °C, 1 h; (c) CH2=CH...
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Scheme 3: Reagents and conditions: (a) POCl3, 150 °C, 6 h, 85%; (b) cyclopropylamine, xylene, 105 °C, 4 h, 99...
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Figure 3: Docked orientations of nevirapine (green), 9 (yellow), 5, and 6 (atom type color – carbon: grey, ch...
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