3 article(s) from Novosjolova, Irina
Synthetic pathways for the synthesis of 6-substituted 2-triazolylpurine derivatives IV.
Jump to Scheme 1
Synthesis of 2,6-bistriazolylpurine derivatives 2a–c.
Jump to Scheme 2
Synthesis of 6-alkyloxy-2-triazolylpurine derivatives 3a–f.
Jump to Scheme 3
Synthesis of 6-alkyloxy-2-triazolylpurine nucleosides 3g–j.
Jump to Scheme 4
2,6-Bistriazolylpurine derivatives in SNAr reactions with H2O/HO− as nucleophiles.
Jump to Scheme 5
Synthesis of C6-substituted 2-triazolylpurine derivatives 5.
Jump to Scheme 6
Possible tautomeric structures of compounds 5a–d.
Jump to Figure 1
Beilstein J. Org. Chem. 2021, 17, 410–419, doi:10.3762/bjoc.17.37
Structural diversity and synthetic methods of purinylphosphonates. MWI = microwave irradiation; LG ...
Synthetic routes for the formation of purinylphosphonates 4.
Synthesis of phosphonates 2, 7, and 8.
Synthesis of phosphonic acid monoesters 3 and 7–9 as well as phosphonic acid 10.
Screenings of the rate for the ester group cleavage (conversion determined by NMR spectroscopy) in ...
Synthesis of 2,6-bistriazolylpurine derivatives 6a–i.
SNAr–Arbuzov reaction between the bistriazolylpurines 6a–i and P(OEt)3.
Single-crystal X-ray analysis of diethyl (9-heptyl-2-(4-phenyl-1H-1,2,3-triazol-1-yl)-9H-purin-6-yl...
Jump to Figure 2
Beilstein J. Org. Chem. 2021, 17, 193–202, doi:10.3762/bjoc.17.19
Examples of fluorescent purine/7-deazapurine derivatives.
General synthetic routes for the compounds 5, 7–9, 10 and 11. Method A: alkyl halogenide, MeCN or D...
1H NMR spectra of compound 6b in CD3CN at different temperatures (300 MHz, c = 12.5 mg/mL); a, b, c...
Comparison of 1H NMR spectra of compounds 8a and 5 (300 MHz, CDCl3).
Jump to Figure 3
a) Experimental UV–vis absorption spectra (lines) with computed theoretical absorption bands (colum...
Jump to Figure 4
Photos of compound 8c (A and B) and compound 11c (C and D) in THF, CHCl3, DMSO, MeCN and MeOH befor...
Jump to Figure 5
a) Fluorescence spectra of compounds 8c (λexc = 360 nm) and 11c (λexc = 370 nm) in solvents of diff...
Jump to Figure 6
Energy diagram for the frontier molecular orbitals of compounds 8a, 8c, 11a and 11c.
Jump to Figure 7
Labeled MCF-7 cells using compound 9 (C,D) and unlabeled MCF-7 cells (A,B) in microscope (2 h, c(9)...
Jump to Figure 8
Beilstein J. Org. Chem. 2019, 15, 474–489, doi:10.3762/bjoc.15.41
Subscribe to our Latest Articles RSS Feed.
Register and get informed about new articles.
Follow the Beilstein-Institut