3 article(s) from Ohmiya, Hirohisa
Graphical Abstract
Scheme 1: Our strategy.
Scheme 2: Allylic cross-coupling using aldehydes as α-alkoxyalkyl anions.
Scheme 3: Substrate scope and reaction conditions. a) reactions were carried out with 1 (0.4 mmol), 2 (0.2 mm...
Scheme 4: Stoichiometric reaction.
Scheme 5: Possible pathway.
Graphical Abstract
Scheme 1: Conjugate addition of alkylborane 2a to alkynoate 3a.
Scheme 2: Synthesis of five membered carbocycle.
Scheme 3: Deuterium-labeling experiment.
Figure 1: Possible mechanism.
Figure 2: Isomerization of the alkenylcopper intermediates.
Graphical Abstract
Figure 1: Azepine frameworks found in natural products and pharmaceuticals.
Figure 2: Semihollow-shaped triethynylphosphine L1.
Figure 3: Time–conversion profiles for the gold-catalyzed cyclization of 4a with L1, X-Phos and IPr ligands.
Scheme 1: 8-exo-dig cyclization of sulfonamide 9.
Scheme 2: Isomerization experiments of 6a.
Figure 4: Possible pathway for the gold-catalyzed conversion of 4a into 5a.