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Search for "complementarity" in Full Text gives 58 result(s) in Beilstein Journal of Organic Chemistry.

Ratiometric fluorescent probe for enantioselective detection of D-cysteine in aqueous solution

  • Xiao-bo Zhou,
  • Wing-Hong Chan,
  • Albert W. M. Lee and
  • Chi-Chung Yeung

Beilstein J. Org. Chem. 2011, 7, 1508–1515, doi:10.3762/bjoc.7.176

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  • health [32]. On the basis of multipoint electrostatic interactions and structure complementarity of the host–guest, we have rationally designed and synthesised a bis(spiropyran) as a fluorescence turn-on probe for selective binding of GSH [33]. We have also developed the first spiropyran–metal sensing
  • enantioselectivity of 3.35 conferred by the chiral trans-1,2-diaminocyclohexane moiety for recognizing D-cysteine in 1% ACN/HEPES buffered solutions (pH 7.4) (Figure 5). Apparently, owing to the structure complementarity of the host–guest, D-cysteine outperforms its enantiomer in forming a more stable complex with
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Published 09 Nov 2011

Supramolecular FRET photocyclodimerization of anthracenecarboxylate with naphthalene-capped γ-cyclodextrin

  • Qian Wang,
  • Cheng Yang,
  • Gaku Fukuhara,
  • Tadashi Mori,
  • Yu Liu and
  • Yoshihisa Inoue

Beilstein J. Org. Chem. 2011, 7, 290–297, doi:10.3762/bjoc.7.38

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  • non-covalent interactions in the ground state [4][5][6][7][8][9][10][11]. The geometrical and functional complementarity and the subsequent induced fit between chiral host and guest substrate should play a crucial role in determining the stereochemical fate of chiral photoreaction, and therefore the
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Published 07 Mar 2011

Fluorometric recognition of both dihydrogen phosphate and iodide by a new flexible anthracene linked benzimidazolium-based receptor

  • Kumaresh Ghosh and
  • Debasis Kar

Beilstein J. Org. Chem. 2011, 7, 254–264, doi:10.3762/bjoc.7.34

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  • ][42][43][44][45]. Iodide binding induced quenching of emission is attributed to the i) complementarity in size of iodide with the pseudocavity formed by the receptor-binding site and ii) heavy atom effect of iodide, which is also true for Br−. But the small quenching of emission in the presence of Br
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Published 25 Feb 2011

Catalysis: transition-state molecular recognition?

  • Ian H. Williams

Beilstein J. Org. Chem. 2010, 6, 1026–1034, doi:10.3762/bjoc.6.117

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  • of enzymes was due to structural complementarity with the TS rather than the reactant state of the substrate [3]: “enzymes are molecules that are complementary in structure to the activated complexes of the reactions they catalyse … [which] would thus lead to a decrease in its energy, and hence to a
  • the TS and should cause an acceleration by forcing bound substrates to resemble the TS” [5]. However, the clear logical implications of the notion of TS complementarity for understanding the origins of enzyme catalytic power were described eloquently (but with a friendly tongue in cheek) by R. L
  • present discussion. Recently, some authors have sought to go “beyond the Pauling paradigm” by noting that “enzymes enter into reactions with substrates and do not merely complement the transition states of the uncatalysed reactions” [9]. The implication seems to be that the notion of TS complementarity
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Commentary
Published 03 Nov 2010

Molecular recognition of organic ammonium ions in solution using synthetic receptors

  • Andreas Späth and
  • Burkhard König

Beilstein J. Org. Chem. 2010, 6, No. 32, doi:10.3762/bjoc.6.32

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  • selective recognition of ammonium ions depends on steric and molecular complementarity and the pre-organization [17] of interacting functional groups. As far back as 1890, Fischer suggested that enzyme–substrate interactions function like a “lock and key” between an initially empty host and a guest that
  • exhibit molecular complementarity [18]. Today studies of non-covalent interactions, mainly by artificial model structures and receptors, have led to a far better understanding of many biological processes. Moreover, they are often the inspiration for supramolecular research, including self-assembly
  • interactions [23][24] and steric complementarity [25]. The crucial interaction mechanisms have been comprehensively summarized [26][27]; basic rules for receptors and design have been outlined [28][29]. As in nature, molecular recognition can either be static – a complexation reaction with defined
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Published 06 Apr 2010

Synthesis and binding studies of two new macrocyclic receptors for the stereoselective recognition of dipeptides

  • Ana Maria Castilla,
  • M. Morgan Conn and
  • Pablo Ballester

Beilstein J. Org. Chem. 2010, 6, No. 5, doi:10.3762/bjoc.6.5

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  • receptor converge toward the center of the macrocycle. The macrocycle is large enough to accommodate the threading dipeptide without incurring any substantial steric clashes. We also observed appropriate complementarity between the hydrogen-bonding groups of substrate and receptor (Figure 3). The analysis
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Published 19 Jan 2010

Self-association of an indole based guanidinium-carboxylate-zwitterion: formation of stable dimers in solution and the solid state

  • Carolin Rether,
  • Wilhelm Sicking,
  • Roland Boese and
  • Carsten Schmuck

Beilstein J. Org. Chem. 2010, 6, No. 3, doi:10.3762/bjoc.6.3

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  • of directed, H-bond assisted salt-bridges is crucial. Zwitterion 1 combines in a near perfect fit geometrical self-complementarity with the possibility to form two salt-bridges assisted by a network of six H-bonds. The superior stability of 1·1 compared to analogous zwitterions based on other
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Published 14 Jan 2010
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  • piperidines 22C and 22D are summarised in Figure 5. Two-directional synthesis of aza-C-linked disaccharide derivatives With the scope, limitations and complementarity of the dihydroxylations established, we turned to the two-directional synthesis of aza-C-linked disaccharide derivatives. The required starting
  • outcome is different in each of the rings (syn to one hydroxyl group, and anti to the other). With a substituent in the 6-position of the piperidine ring, the complementarity between the alternative methods was lost. With the substrates 29, trans-27 and trans-33, dihydroxylation occurred anti to the
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Published 26 Aug 2005
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