Diarylethene-modified nucleotides for switching optical properties in DNA

• Sebastian Barrois and
• Hans-Achim Wagenknecht

Beilstein J. Org. Chem. 2012, 8, 905–914, doi:10.3762/bjoc.8.103

• [1][2][3][4]. Nucleic acids are synthesized by building blocks; in this bottom-up approach artificial functionalities, such as photoswitches, can be introduced synthetically by providing the corresponding artificial DNA building block. Among the known and structurally diverse photochromic compounds

Building photoswitchable 3,4'-AMPB peptides: Probing chemical ligation methods with reducible azobenzene thioesters

• Gehad Zeyat and
• Karola Rück-Braun

Beilstein J. Org. Chem. 2012, 8, 890–896, doi:10.3762/bjoc.8.101

• of photoswitches, and typical applications based on light-triggered reversible conformational control of cyclic, helical or beta-hairpin peptides have been intensively reviewed [2][3]. Current research in this field focuses on advanced methods and designs for the synthesis of complex azopeptides and

Molecular switches and cages

• Dirk Trauner

Beilstein J. Org. Chem. 2012, 8, 870–871, doi:10.3762/bjoc.8.97

• synthetic switches, complementing the many types found in nature. Given their prominence in biology, it is not surprisingly that photoswitches, which are actuated by ultraviolet, visible or infrared light, have been an especially productive field of study. Despite their long history, new types of synthetic

• photoswitches continue to emerge and “old friends”, such as azobenzenes are constantly improved and optimized. This is not only true with respect to their photophysical properties but also with regard to their synthetic accessibility. Indeed, as molecular switches are applied in ever-increasing quantities, the

• compounds but in its infancy in the case of reversible photoswitches. The present Thematic Series of the Beilstein Journal of Organic Chemistry addresses the crucial role that chemistry, and particularly organic chemistry, can play in tuning the functional features of molecular switches and cages. These

Synthesis of novel photochromic pyrans via palladium- mediated reactions

• Christoph Böttcher,
• Gehad Zeyat,
• Saleh A. Ahmed,
• Elisabeth Irran,
• Thorben Cordes,
• Cord Elsner,
• Wolfgang Zinth and
• Karola Rueck-Braun

Beilstein J. Org. Chem. 2009, 5, No. 25, doi:10.3762/bjoc.5.25

• -electronic devices, e.g. as logic gates [1]. In the life sciences, functionalized azobenzenes [6], hemithioindigos [7][8] and fulgimides [9][10] among other classes of photoswitches, have already proven to be valuable tools for photo-controlling the structure and function of complex biomolecules [6][7][8][9