Synthesis of rigidified flavin–guanidinium ion conjugates and investigation of their photocatalytic properties

• Harald Schmaderer,
• Mouchumi Bhuyan and
• Burkhard König

Beilstein J. Org. Chem. 2009, 5, No. 26, doi:10.3762/bjoc.5.26

• ; Introduction Flavins are redox-active chromophores [1][2][3][4][5][6] and represent one of the most abundant classes of natural enzyme co-factors [7][8][9]. Recently, the photo redox properties of flavins have been used to catalyze chemical reactions [10][11][12][13][14][15][16][17][18][19][20][21][22][23][24

Continuous flow based catch and release protocol for the synthesis of α-ketoesters

• Alessandro Palmieri,
• Steven V. Ley,
• Anastasios Polyzos,
• Mark Ladlow and
• Ian R. Baxendale

Beilstein J. Org. Chem. 2009, 5, No. 23, doi:10.3762/bjoc.5.23

• and release; flow synthesis; α-ketoesters; mesoreactor; polymer supported reagents; Introduction Organic synthesis is changing rapidly owing to the discovery of processes that challenge current dogma and lead to the invention of new chemical reactions [1][2]. Likewise, new synthesis tools are

Asymmetric reactions in continuous flow

• Xiao Yin Mak,
• Paola Laurino and
• Peter H. Seeberger

Beilstein J. Org. Chem. 2009, 5, No. 19, doi:10.3762/bjoc.5.19

• alternatives to the traditional ‘round-bottomed flask’ concept, which is still typically widely used for most chemical reactions [1][2][3][4][5][6][7][8]. Many advantages have been attributed to the use of flow devices, such as improved heat and mass transfer as well as mixing, and also easier scale-up and

Synthesis of unsymmetrically substituted biaryls via sequential lithiation of dibromobiaryls using integrated microflow systems

• Aiichiro Nagaki,
• Naofumi Takabayashi,
• Yutaka Tomida and
• Jun-ichi Yoshida

Beilstein J. Org. Chem. 2009, 5, No. 16, doi:10.3762/bjoc.5.16

• conducting reactions without decomposing such intermediates [34][35][36][37][38][39][40]. Moreover, microflow systems serve as effective ways of integrating chemical reactions, in which an initial product is used for a subsequent transformation [41][42][43][44][45][46][47][48][49][50][51]. For example

Photosonochemical catalytic ring opening of α-epoxyketones

• Hamid R. Memarian and
• Ali Saffar-Teluri

Beilstein J. Org. Chem. 2007, 3, No. 2, doi:10.1186/1860-5397-3-2

• chemical reactions include higher yields, shorter reaction times and milder reaction conditions when compared with classical methods. [1][2][3][4][5] The effect of ultrasound has mostly been shown by increasing the yields of reactions and in some cases changing the ratio of products formed. The most

Study of thioglycosylation in ionic liquids

• Jianguo Zhang and
• Arthur Ragauskas

Beilstein J. Org. Chem. 2006, 2, No. 12, doi:10.1186/1860-5397-2-12

• polarity can be routinely accomplished by altering the nature of the ion pair or altering the nature of the alkyl group on the substituted organic cation.[2] These structural variations substantially broaden the scope and versatility of ILs applications. Many chemical reactions have been carried out in

EcoScale, a semi- quantitative tool to select an organic preparation based on economical and ecological parameters

• Koen Van Aken,
• Lucjan Strekowski and
• Luc Patiny

Beilstein J. Org. Chem. 2006, 2, No. 3, doi:10.1186/1860-5397-2-3

• between 100–1000 on the basis of their toxicity. Based on the environmental quotient, a computer program has been developed (EATOS of Environmental Assessment Tool for Organic Synthesis) [11] that can be used to compare and improve chemical reactions. Effective mass yield [12] This parameter is defined as