The enantiospecific synthesis of (+)-monomorine I using a 5-endo- trig cyclisation strategy

• Malcolm B. Berry,
• Donald Craig,
• Philip S. Jones and
• Gareth J. Rowlands

Beilstein J. Org. Chem. 2007, 3, No. 39, doi:10.1186/1860-5397-3-39

• , (+)-monomorine I. [10][11][12][13] We have briefly described this work in a previous communication. [4] Results and Discussion The pyrrolidine ring is an important structural motif that occurs in a range of pheromones, venoms and drug candidates. [14] In order to demonstrate the synthetic utility of the sulfone

Allylsilanes in the synthesis of three to seven membered rings: the silylcuprate strategy

• Asunción Barbero,
• Francisco J. Pulido and
• M. Carmen Sañudo

Beilstein J. Org. Chem. 2007, 3, No. 16, doi:10.1186/1860-5397-3-16

• substituted cyclobutenes after cyclization of the vinylsilane or vinylstannane intermediate. [23] Cyclization of the corresponding vinylsilanes gave poor results of no synthetic utility, however the vinylstannane strategy results in formation of 1- and 3-substituted cyclobutenes 42 and 43 in good yield

Synthesis of spiropyrans: H-abstractions in 3-cycloalkenyloxybenzopyrans

• Satish C. Gupta,
• Mandeep Thakur,
• Somesh Sharma,
• Urmila Berar,
• Surinder Berar and
• Ramesh C. Kamboj

Beilstein J. Org. Chem. 2007, 3, No. 14, doi:10.1186/1860-5397-3-14

• cyclisations and [4+2] cycloadditions. [11][12][13][14][15][16] These methods being specific in nature for a particular spirocyclic compound, offer limited synthetic utility. In the past, we have investigated the use of photochemical methods for the synthesis of organic molecules like vinyl ethers, [17

Synthesis of highly substituted allenylsilanes by alkylidenation of silylketenes

• Stephen P. Marsden and
• Pascal C. Ducept

Beilstein J. Org. Chem. 2005, 1, No. 5, doi:10.1186/1860-5397-1-5

• chemistry undertaken by allenylsilanes, we expect that these new highly functionalised members of the class will find broad synthetic utility. Our own studies on their application in heterocyclic synthesis will be disclosed in due course. Description of Supporting Information Supporting Information features