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Search for "1-indanones" in Full Text gives 5 result(s) in Beilstein Journal of Organic Chemistry.
Beyond n-dopants for organic semiconductors: use of bibenzo[d]imidazoles in UV-promoted dehalogenation reactions of organic halides
Beilstein J. Org. Chem. 2023, 19, 1912–1922, doi:10.3762/bjoc.19.142
- been used by Murphy’s group and others for a variety of transformations, such as the formation of indolines from N-allyl-2-iodoanilines [1], indanones from 3-(2-halophenyl)propanoic esters [2][3], and 3-methyl-2,3-dihydrobenzofuran from 1-allyloxy-2-halobenzenes [4]. Related species have also been used
New advances in asymmetric organocatalysis
Beilstein J. Org. Chem. 2022, 18, 240–242, doi:10.3762/bjoc.18.28
- nitromethane to β-silyl α,β-unsaturated carbonyl compounds catalyzed by bifunctional squaramide catalysts are effective under solvent-free conditions [26]. Zhai and Du demonstrated that asymmetric [3 + 2] annulation reactions of 2-isothiocyanato-1-indanones with barbiturate-based olefins are efficiently
Bifunctional thiourea-catalyzed asymmetric [3 + 2] annulation reactions of 2-isothiocyanato-1-indanones with barbiturate-based olefins
Beilstein J. Org. Chem. 2022, 18, 25–36, doi:10.3762/bjoc.18.3
- -isothiocyanato-1-indanones with barbiturate-based olefins have been developed to afford chiral dispiro[indene-pyrrolidine-pyrimidine]s. Through this strategy, the target products could be obtained in good to excellent yields with excellent stereoselectivities. In addition, the synthetic utility was verified
- reaction. Based on the above evaluation, we finally selected 2-isothiocyanato-1-indanones 1 and barbiturate-based olefins 2 with a molar ratio of 1.2:1 to react for 12 h at room temperature in DCM using 5 mol % of catalyst C4 as the optimum reaction conditions. With the optimum reaction conditions
- established, we then commenced to probe the substrate scope and limitations of this reaction. As summarized in Scheme 2, a variety of 2-isothiocyanato-1-indanones 1 were firstly tested under the optimized conditions. When a methyl substituent is located at the 6-position of the indanone, the reaction yield of
Synthesis of 1-indanones with a broad range of biological activity
Beilstein J. Org. Chem. 2017, 13, 451–494, doi:10.3762/bjoc.13.48
- .13.48 Abstract This comprehensive review describes methods for the preparation of 1-indanones published in original and patent literature from 1926 to 2017. More than 100 synthetic methods utilizing carboxylic acids, esters, diesters, acid chlorides, ketones, alkynes, alcohols etc. as starting materials
- , have been performed. This review also covers the most important studies on the biological activity of 1-indanones and their derivatives which are potent antiviral, anti-inflammatory, analgesic, antimalarial, antibacterial and anticancer compounds. Moreover, they can be used in the treatment of
- neurodegenerative diseases and as effective insecticides, fungicides and herbicides. Keywords: biological activity; Diels–Alder reaction; Friedel–Crafts reaction; 1-indanones; Nazarov reaction; Introduction In the last few years, 1-indanone derivatives and their structural analogues have been widely used in
(CF3CO)2O/CF3SO3H-mediated synthesis of 1,3-diketones from carboxylic acids and aromatic ketones
Beilstein J. Org. Chem. 2014, 10, 2270–2278, doi:10.3762/bjoc.10.236
- acids and aromatic ketones in TFAA/TfOH system is described. When the β-phenylpropionic acids were used as starting materials, they initially gave 1-indanones and then underwent further acylation with the formation of 2-(β-phenylpropionyl)-1-indanones as the main reaction products. In addition, the
- cyclization of 3-arylpropanoic and 4-arylbutanoic acids to 1-indanones and 1-tetralones is well-known [12][13][14][15][16][17][18], but it appears that the further acylation and β-diketone formation has not been reported yet. While the use of acyl trifluoroacetates, generated in situ from a carboxylic acid
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