Search results
Search for "kinetic studies" in Full Text gives 88 result(s) in Beilstein Journal of Organic Chemistry.
New efficient ligand for sub-mol % copper-catalyzed C–N cross-coupling reactions running under air
Beilstein J. Org. Chem. 2012, 8, 1909–1915, doi:10.3762/bjoc.8.221
- could be involved in the mass transfer of the heterogeneous base. Conclusion In summary, a new and efficient ligand (DMDETA) for sub-mol % copper-catalyzed C–N cross coupling has been synthesized and evaluated in kinetic studies. DMDETA, together with DMEDA, is one of the few reported ligands that work
Self-assembled organic–inorganic magnetic hybrid adsorbent ferrite based on cyclodextrin nanoparticles
Beilstein J. Org. Chem. 2012, 8, 1867–1876, doi:10.3762/bjoc.8.215
- microscopy (AFM). Size distribution and colloidal suspension stability were characterized by dynamic light scattering (DLS) and sedimentation kinetic studies by using UV–vis spectroscopy. Ferrite binding sites were characterized by zeta potential (ZP) and potentiometric titration. The free volume for both
Palladium-catalyzed dual C–H or N–H functionalization of unfunctionalized indole derivatives with alkenes and arenes
Beilstein J. Org. Chem. 2012, 8, 1730–1746, doi:10.3762/bjoc.8.198
- moderate to good yield (Scheme 6). A mechanism including an electrophilic palladation involving the pyridinyl chelation was thought to be plausible taking into account the outcome of the reaction performed on isotopically labeled substrates as well as by kinetic studies of variously substituted indoles
A quantitative approach to nucleophilic organocatalysis
Beilstein J. Org. Chem. 2012, 8, 1458–1478, doi:10.3762/bjoc.8.166
- chromatography on silica gel. The presence of triethylamine (5%) in the eluent (ethyl acetate/n-pentane) turned out to be crucial to avoid decomposition of these enamines on the column [82][83]. Kinetic studies of their reactions with benzhydrylium ions 18 of suitable electrophilicity showed that introduction of
- ], we synthesized and isolated the O-methylated Breslow intermediates 55a–c, 57, and 59 as described in Figure 27 [114]. Some of them were characterized by single-crystal X-ray crystallography. Kinetic studies of their reactions with benzhydrylium ions provided their reactivity parameters N and sN [114
Studies on the substrate specificity of a GDP-mannose pyrophosphorylase from Salmonella enterica
Beilstein J. Org. Chem. 2012, 8, 1219–1226, doi:10.3762/bjoc.8.136
- )(OBn)2, NIS, AgOTf, CH2Cl2, 67%; (e) (i) H2, Pd(OH)2–C, toluene, Et3N, pyridine; (ii) CH3OH–H2O–Et3N, 5:2:1, 72%. KM, kcat, and kcat/KM of GDP-ManPP kinetic studies. Supporting Information Supporting Information File 372: Detailed experimental procedures. Acknowledgements This work was supported by
Recent advances towards azobenzene-based light-driven real-time information-transmitting materials
Beilstein J. Org. Chem. 2012, 8, 1003–1017, doi:10.3762/bjoc.8.113
- substitution (type-I), that is, bearing a push–pull configuration. Secondly, kinetic studies of different azophenolic systems (type-II) will be presented, since these azoderivatives exhibit a fast thermal back reaction due to their capability to establish an azo-hydrazone tautomeric equilibrium. Both type-I
New library of aminosulfonyl-tagged Hoveyda–Grubbs type complexes: Synthesis, kinetic studies and activity in olefin metathesis transformations
Beilstein J. Org. Chem. 2010, 6, 1159–1166, doi:10.3762/bjoc.6.132
- Chimie de Rennes, Av. du Général Leclerc, CS 50837 35708 Rennes cedex 7, France 10.3762/bjoc.6.132 Abstract Seven novel Hoveyda–Grubbs precatalysts bearing an aminosulfonyl function are reported. Kinetic studies indicate an activity enhancement compared to Hoveyda’s precatalyst. A selection of these
- catalysts was investigated with various substrates in ring-closing metathesis of dienes or enynes and cross metathesis. The results demonstrate that these catalysts show a good tolerance to various chemical functions. Keywords: cross-metathesis; kinetic studies; olefin metathesis; RCM; ruthenium
- between the SIPr unit and the electronic activation of the benzylidene fragment. Conclusion A new library of Hoveyda type catalysts bearing aminosulfonyl functions has been synthesized. Their activity profiles have been investigated through kinetic studies and through evaluation of a group of substrates
Kinetics and mechanism of vanadium catalysed asymmetric cyanohydrin synthesis in propylene carbonate
Beilstein J. Org. Chem. 2010, 6, 1043–1055, doi:10.3762/bjoc.6.119
- achieved at atmospheric pressure and room temperature [74][75][76][77], or in a gas-phase continuous flow reactor [78], thus facilitating the use of waste carbon dioxide in this process [79]. In this paper we give full details of the use of catalyst 2 in propylene carbonate, and describe kinetic studies
Novel multi-responsive P2VP-block-PNIPAAm block copolymers via nitroxide-mediated radical polymerization
Beilstein J. Org. Chem. 2010, 6, 756–765, doi:10.3762/bjoc.6.89
- molecular weight distributions. The best reaction conditions, optimized by kinetic studies, were bulk polymerization at 110 °C. Using P2VP as a macroinitiator, the synthesis of new soluble linear block copolymers of P2VP and poly(N-isopropylacrylamide) (PNIPAAm) (P2VP-block-PNIPAAm) was possible. The
Kinetic studies and predictions on the hydrolysis and aminolysis of esters of 2-S-phosphorylacetates
Beilstein J. Org. Chem. 2010, 6, 732–741, doi:10.3762/bjoc.6.87
- 2 in such a way as to favour aminolysis over undesired hydrolysis processes. In addition to kinetic studies, we present predictions of leaving group characteristics, based on correlation with literature data, that should allow for improvement in the performance of 2-bromoacetic acid esters 1 as
- /MeCN solvent system was employed where the reagents formed homogeneous solutions that we hoped to use for simple kinetic studies. When using the N-hydroxybenzotriazole system (leaving group pKaH = 4.60 [5]), we performed several experiments at different pH values and at concentrations of ~0.02 M for
- , we did not pursue the use of this system any further. In order to gain an understanding of the aminolysis vs hydrolysis processes, we re-focused our studies towards activated bromoacetic acid phenyl ester systems that were more readily amenable to kinetic studies via UV–vis spectrophotometry. The 2
Synthesis, characterization and photoinduced curing of polysulfones with (meth)acrylate functionalities
Beilstein J. Org. Chem. 2010, 6, No. 56, doi:10.3762/bjoc.6.56
- is due to the additional acrylate and methacrylate moieties incorporated. Kinetic studies concerning photopolymerization of the macromonomers were performed by photo-DSC. The results are shown in Figure 3 and Figure 4. The rate of photopolymerization vs. time plots for both PSU-DA-2000 and PSU-DM
Thematic series on supramolecular chemistry
Beilstein J. Org. Chem. 2009, 5, No. 76, doi:10.3762/bjoc.5.76
- recognition.” [1] As the above citation from a paper by Julius Rebek and his coworkers indicates, supramolecular chemistry at its beginning gave new impetus to physical organic chemistry, which at that time had got trapped in ever more detailed kinetic studies. Early on, the nature of non-covalent
The Elbs and Boyland- Sims peroxydisulfate oxidations
Beilstein J. Org. Chem. 2006, 2, No. 22, doi:10.1186/1860-5397-2-22
- obvious choice that was supported by a number of kinetic studies. [1] This was questioned by Edward and Whiting [2] who claimed that the molecule formed by sulfonating N,N-dimethylaniline-N-oxide(1) did not rearrange to the o-sulfate(2) but rather decomposed by hydrolysis. However, repetition of this work
Other Beilstein-Institut Open Science Activities
