Metal-free aerobic oxidations mediated by N-hydroxyphthalimide. A concise review

• Lucio Melone and
• Carlo Punta

Beilstein J. Org. Chem. 2013, 9, 1296–1310, doi:10.3762/bjoc.9.146

• cellulose fibers promoted by the NaClO/NaBr system (Scheme 16). According to the proposed mechanism PINO radical is oxidized to the corresponding N-oxammonium cation, which in turn is responsible for the oxidation of the C6 alcoholic function. The surface modification of cellulose fibers by selectively

Towards a biocompatible artificial lung: Covalent functionalization of poly(4-methylpent-1-ene) (TPX) with cRGD pentapeptide

• Lena Möller,
• Christian Hess,
• Jiří Paleček,
• Yi Su,
• Axel Haverich,
• Andreas Kirschning and
• Gerald Dräger

Beilstein J. Org. Chem. 2013, 9, 270–277, doi:10.3762/bjoc.9.33

• ); surface modification; Introduction Respiratory failures are a significant health-care problem with several hundred thousand adult patients each year [1]. Besides medical treatment, the use of mechanical ventilators that provide breathing support while the lungs recover, is often indispensable. This

• 2 with a methanolic solution of nitrene precursor 3, and then drying followed by UV irradiation (Hg lamp, 254 nm) initially did not lead to surface modification. The presence of F and N on the TPX membrane was not detectable by XPS analysis. The photoinduced reaction of azide 3 with cyclohexane

Cyclodextrin-based nanosponges as drug carriers

• Francesco Trotta,
• Marco Zanetti and
• Roberta Cavalli

Beilstein J. Org. Chem. 2012, 8, 2091–2099, doi:10.3762/bjoc.8.235

• ability of the nanosponges. Acid nanosponges carrying free carboxylic groups can be obtained using pyromellitic anhydride or other dianhydrides as a cross-linker, forming true cation exchange sites. The presence of free hydroxy groups in the nanosponges network allows further surface modification. For

Mannose-decorated cyclodextrin vesicles: The interplay of multivalency and surface density in lectin–carbohydrate recognition

• Ulrike Kauscher and
• Bart Jan Ravoo

Beilstein J. Org. Chem. 2012, 8, 1543–1551, doi:10.3762/bjoc.8.175

• ; cyclodextrins; lectins; molecular recognition; multivalency; vesicles; Introduction The surface modification of materials with carbohydrates has attracted much attention due to the fact that such materials can be compared to and compatible with the cell surface [1]. The “glycocalyx” is a dense layer on the

Pseudo five-component synthesis of 2,5-di(hetero)arylthiophenes via a one-pot Sonogashira–Glaser cyclization sequence

• Dominik Urselmann,
• Dragutin Antovic and
• Thomas J. J. Müller

Beilstein J. Org. Chem. 2011, 7, 1499–1503, doi:10.3762/bjoc.7.174

• strikingly simple methodology is highly practical and leads to a straightforward protocol for the preparation of the title compounds. Studies addressing more-sophisticated 2,5-disubstituted thiophenes for surface modification and also mesoporous hybrid materials are currently underway. Experimental 2c: An 80

ROMP-Derived cyclooctene-based monolithic polymeric materials reinforced with inorganic nanoparticles for applications in tissue engineering

• Franziska Weichelt,
• Solvig Lenz,
• Stefanie Tiede,
• Ingrid Reinhardt,
• Bernhard Frerich and
• Michael R. Buchmeiser

Beilstein J. Org. Chem. 2010, 6, 1199–1205, doi:10.3762/bjoc.6.137

• :4 ratio and amplified up to the third passage. Sterilization of the samples was accomplished with γ-irradiation with the aid of a 60Co-γ-source at the Leibniz-Institute of Surface Modification (IOM, Leipzig, Germany) on a rotating table at a dose rate of 0.79 kGy/h. The dose rate was determined by

Hybrid biofunctional nanostructures as stimuli-responsive catalytic systems

• Gernot U. Marten,
• Thorsten Gelbrich and
• Annette M. Schmidt

Beilstein J. Org. Chem. 2010, 6, 922–931, doi:10.3762/bjoc.6.98

• (Diamond): ν (cm−1) = 2357, 2335 (C-N), 1247 (OH), 1098 (C-O), 1080 (OH). Surface modification of Fe3O4 nanoparticles: For the immobilization of initiator sites on the particle surface of Fe3O4@CA, the dispersion was diluted with ethanol to a mass content of 1.0 g·l−1, and 1.80 mmol CPS per gram of Fe3O4