Antibacterials, bacterial small molecule interactions and quorum sensing

  1. editorImage
  1. Editor: Prof. David R. Spring
    University of Cambridge


“Antibacterials, bacterial small molecule interactions and quorum sensing” has become a highly active research area due to the basic science challenge and the ever-increasing problems with antimicrobial resistance.

 Potential topics for manuscripts include, but are not limited to:

  • Discovery, investigation and/or mechanism of antibacterial molecules
  • Discovery, investigation and/or mechanism of molecules that are involved in or modulate bacterial signaling/quorum sensing
  • Synthesis of antibacterial molecules
  • Library synthesis

Additional articles on this topic will be published here soon.

Natural and redesigned wasp venom peptides with selective antitumoral activity

  1. Marcelo D. T. Torres,
  2. Gislaine P. Andrade,
  3. Roseli H. Sato,
  4. Cibele N. Pedron,
  5. Tania M. Manieri,
  6. Giselle Cerchiaro,
  7. Anderson O. Ribeiro,
  8. Cesar de la Fuente-Nunez and
  9. Vani X. Oliveira Jr.
  • Full Research Paper
  • Published 06 Jul 2018

  • PDF

Beilstein J. Org. Chem. 2018, 14, 1693–1703, doi:10.3762/bjoc.14.144

Defining the hydrophobic interactions that drive competence stimulating peptide (CSP)-ComD binding in Streptococcus pneumoniae

  1. Bimal Koirala,
  2. Robert A. Hillman,
  3. Erin K. Tiwold,
  4. Michael A. Bertucci and
  5. Yftah Tal-Gan
  • Full Research Paper
  • Published 16 Jul 2018

  • PDF

  • Supp. Info

Beilstein J. Org. Chem. 2018, 14, 1769–1777, doi:10.3762/bjoc.14.151

Synthesis of a leopolic acid-inspired tetramic acid with antimicrobial activity against multidrug-resistant bacteria

  1. Luce Mattio,
  2. Loana Musso,
  3. Leonardo Scaglioni,
  4. Andrea Pinto,
  5. Piera Anna Martino and
  6. Sabrina Dallavalle
  • Letter
  • Published 24 Sep 2018

  • PDF

  • Supp. Info

Beilstein J. Org. Chem. 2018, 14, 2482–2487, doi:10.3762/bjoc.14.224

Impact of Pseudomonas aeruginosa quorum sensing signaling molecules on adhesion and inflammatory markers in endothelial cells

  1. Carmen Curutiu,
  2. Florin Iordache,
  3. Veronica Lazar,
  4. Aurelia Magdalena Pisoschi,
  5. Aneta Pop,
  6. Mariana Carmen Chifiriuc and
  7. Alina Maria Hoban
  • Full Research Paper
  • Published 05 Oct 2018

  • PDF

Beilstein J. Org. Chem. 2018, 14, 2580–2588, doi:10.3762/bjoc.14.235

  • Review
  • Published 15 Oct 2018

  • PDF

Beilstein J. Org. Chem. 2018, 14, 2627–2645, doi:10.3762/bjoc.14.241

The design and synthesis of an antibacterial phenothiazine–siderophore conjugate

  1. Abed Tarapdar,
  2. James K. S. Norris,
  3. Oliver Sampson,
  4. Galina Mukamolova and
  5. James T. Hodgkinson
  • Letter
  • Published 16 Oct 2018

Beilstein J. Org. Chem. 2018, 14, 2646–2650, doi:10.3762/bjoc.14.242

  • Full Research Paper
  • Published 17 Oct 2018

  • PDF

  • Supp. Info

Beilstein J. Org. Chem. 2018, 14, 2651–2664, doi:10.3762/bjoc.14.243

Synthesis and biological evaluation of 1,2-disubstituted 4-quinolone analogues of Pseudonocardia sp. natural products

  1. Stephen M. Geddis,
  2. Teodora Coroama,
  3. Suzanne Forrest,
  4. James T. Hodgkinson,
  5. Martin Welch and
  6. David R. Spring
  • Letter
  • Published 19 Oct 2018

  • PDF

  • Supp. Info

Beilstein J. Org. Chem. 2018, 14, 2680–2688, doi:10.3762/bjoc.14.245

Synthesis of pyrrolidine-based hamamelitannin analogues as quorum sensing inhibitors in Staphylococcus aureus

  1. Jakob Bouton,
  2. Kristof Van Hecke,
  3. Reuven Rasooly and
  4. Serge Van Calenbergh
  • Full Research Paper
  • Published 12 Nov 2018

  • PDF

  • Supp. Info

Beilstein J. Org. Chem. 2018, 14, 2822–2828, doi:10.3762/bjoc.14.260

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