Stereodiscrimination of guests in chiral organosilica aerogels studied by ESR spectroscopy

• Sebastian Polarz,
• Yasar Krysiak,
• Martin Wessig and
• Florian Kuhlmann

Beilstein J. Nanotechnol. 2025, 16, 2034–2054, doi:10.3762/bjnano.16.140

• high surface area and customizable chiral environments. A highly important and highly developed area of application of chiral materials possessing a high surface area is chromatography [11][12][13]. Techniques like high-performance liquid chromatography (HPLC) [13] and gas chromatography [14] are

Prospects of nanotechnology and natural products for cancer and immunotherapy

• Jan Filipe Andrade Santos,
• Marcela Bernardes Brasileiro,
• Pamela Danielle Cavalcante Barreto,
• Ligiane Aranha Rocha and
• José Adão Carvalho Nascimento Júnior

Beilstein J. Nanotechnol. 2025, 16, 1644–1667, doi:10.3762/bjnano.16.116

Photocatalytic degradation of ofloxacin in water assisted by TiO₂ nanowires on carbon cloth: contributions of H₂O₂ addition and substrate absorbability

• Iram Hussain,
• Lisha Zhang,
• Zhizhen Ye and
• Jin-Ming Wu

Beilstein J. Nanotechnol. 2025, 16, 1567–1579, doi:10.3762/bjnano.16.111

• -first-order kinetic model, as determined by Equation 3: The concentration of OFL was assessed using high-performance liquid chromatography with a C18 column maintained at 30 °C. The UV–vis detector was calibrated to a wavelength of 292 nm. The mobile phase consisted of a 15:85 ratio of methanol to 0.8

Ferroptosis induction by engineered liposomes for enhanced tumor therapy

• Alireza Ghasempour,
• Mohammad Amin Tokallou,
• Mohammad Reza Naderi Allaf,
• Mohsen Moradi,
• Hamideh Dehghan,
• Mahsa Sedighi,
• Mohammad-Ali Shahbazi and
• Fahimeh Lavi Arab

Beilstein J. Nanotechnol. 2025, 16, 1325–1349, doi:10.3762/bjnano.16.97

• systems. The EE of liposomes, which determines the amount of drug loaded into the vesicles, can be evaluated by various analytical methods. High-performance liquid chromatography (HPLC) and capillary electrophoresis (CE) are widely used methods to quantify the encapsulated drug [110][125]. HPLC separates

Chitosan nanocomposite containing rotenoids: an alternative bioinsecticidal approach for the management of Aedes aegypti

• Maria A. A. Bertonceli,
• Vitor D. C. Cristo,
• Ivo J. Vieira,
• Francisco J. A. Lemos,
• Arnoldo R. Façanha,
• Raimundo Braz-Filho,
• Gustavo V. T. Batista,
• Luis G. M. Basso,
• Sérgio H. Seabra,
• Thalya S. R. Nogueira,
• Felipe F. Moreira,
• Arícia L. E. M. Assis,
• Antônia E. A. Oliveira and
• Kátia V. S. Fernandes

Beilstein J. Nanotechnol. 2025, 16, 1197–1208, doi:10.3762/bjnano.16.88

• encapsulation efficiency is estimated to be ≥99% within the detection limits of high-performance liquid chromatography (HPLC) and thin-layer chromatography (TLC) methods applied, indicating a highly effective incorporation of the rotenoids into the nanochitosan matrix. In addition to the high encapsulation

• of 1 cm−1 and an accumulation of 35 scans per spectrum. A compressive force of 15 N was applied to the samples during measurement to ensure proper contact with the ATR crystal surface. Quantification of rotenoids by high-performance liquid chromatography The quantification of rotenoids was performed

Synthesis of a multicomponent cellulose-based adsorbent for tetracycline removal from aquaculture water

• Uyen Bao Tran,
• Ngoc Thanh Vo-Tran,
• Khai The Truong,
• Dat Anh Nguyen,
• Quang Nhat Tran,
• Huu-Quang Nguyen,
• Jaebeom Lee and
• Hai Son Truong-Lam

Beilstein J. Nanotechnol. 2025, 16, 728–739, doi:10.3762/bjnano.16.56

• were characterized, and the TC adsorption efficiency of PGC was assessed using high-performance liquid chromatography–mass spectroscopy (HPLC-MS). Elemental analysis of PGC identified four key mechanisms governing its endothermic TC adsorption mechanism: surface complexation, electrostatic interactions

• ‒desorption isotherms at 77.3 K under controlled pressure conditions. Before analysis, the sample was degassed at 150 °C for 2 h and 30 min under an N2 atmosphere. High-performance liquid chromatography-mass spectroscopy (HPLC–MS/MS) The HPLC-MS/MS system consisted of an AB Sciex 4000 QTRAP mass spectrometer

Efficiency of single-pulse laser fragmentation of organic nutraceutical dispersions in a circular jet flow-through reactor

• Tina Friedenauer,
• Maximilian Spellauge,
• Alexander Sommereyns,
• Verena Labenski,
• Tuba Esatbeyoglu,
• Christoph Rehbock,
• Heinz P. Huber and
• Stephan Barcikowski

Beilstein J. Nanotechnol. 2025, 16, 711–727, doi:10.3762/bjnano.16.55

• yield of submicrometer particles and nanoparticles was quantified using UV–vis extinction spectroscopy, scanning electron microscopy, and analytical centrifugation, while high-performance liquid chromatography determined degradation. We found improved fragmentation efficiency at lower mass

• for CBD was 207 nm. The ratio of LP1 to LP0 results in the percentage extinction enhancement that is shown in Figure 2A for curcumin and Figure 2B for CBD. High-performance liquid chromatography The purity of curcumin and CBD was analyzed using a Nexera SCL-40 liquid chromatography system with a DGU

Aprepitant-loaded solid lipid nanoparticles: a novel approach to enhance oral bioavailability

• Mazhar Hussain,
• Muhammad Farooq,
• Muhammad Asad Saeed,
• Muhammad Ijaz,
• Sherjeel Adnan,
• Zeeshan Masood,
• Muhammad Waqas,
• Wafa Ishaq and
• Nabeela Ameer

Beilstein J. Nanotechnol. 2025, 16, 652–663, doi:10.3762/bjnano.16.50

• drug content was determined via high-performance liquid chromatography at λmax = 210 nm. Analysis was performed by utilizing a C18 column (4.6 × 250 mm, 5 μm, Shim-pack Substance, Japan) at a flow rate of 1.5 mL/min and at 40 °C. Tests were performed utilizing a combination of 0.1% phosphoric acid in

Engineered PEG–PCL nanoparticles enable sensitive and selective detection of sodium dodecyl sulfate: a qualitative and quantitative analysis

• Soni Prajapati and
• Ranjana Singh

Beilstein J. Nanotechnol. 2025, 16, 385–396, doi:10.3762/bjnano.16.29

• applications within permissible limits. To assess the safe dose of SDS in other products, various high throughput tools are available, including spectrophotometrics, potentiometrics, high-performance liquid chromatography (HPLC), capillary electrophoresis, and fluorescence-based methods [15][16][17][18][19

Facile synthesis of size-tunable L-carnosine-capped silver nanoparticles and their role in metal ion sensing and catalytic degradation of p-nitrophenol

• Akash Kumar,
• Ridhima Chadha,
• Abhishek Das,
• Nandita Maiti and
• Rayavarapu Raja Gopal

Beilstein J. Nanotechnol. 2024, 15, 1576–1592, doi:10.3762/bjnano.15.124

• heavy metal ion monitoring in environmental samples involve complex analytical instrumental techniques such as atomic absorption spectroscopy, inductively coupled plasma mass spectrometry, and high-performance liquid chromatography [8][9]. Environmental remediation of P-NP requires processes such as

Simultaneous electrochemical determination of uric acid and hypoxanthine at a TiO₂/graphene quantum dot-modified electrode

• Vu Ngoc Hoang,
• Dang Thi Ngoc Hoa,
• Nguyen Quang Man,
• Le Vu Truong Son,
• Le Van Thanh Son,
• Vo Thang Nguyen,
• Le Thi Hong Phong,
• Ly Hoang Diem,
• Kieu Chan Ly,
• Ho Sy Thang and
• Dinh Quang Khieu

Beilstein J. Nanotechnol. 2024, 15, 719–732, doi:10.3762/bjnano.15.60

• URI, associated with the risk of gout [5]. Hence, simple and selective methods to determine the purine content in food and dietary products are of interest among researchers [6][7]. At the present time, several techniques for the determination of URI and HYP are available, such as high-performance

• liquid chromatography [8], liquid chromatography–tandem mass spectrometry [9], and gas chromatography/mass spectrometry [10]. These approaches require complex handling procedures. Electrochemical techniques have been considered as a robust alternative for URI and HYP sensing because of their simplicity

Development and characterization of potential larvicidal nanoemulsions against Aedes aegypti

• Jonatas L. Duarte,
• Leonardo Delello Di Filippo,
• Anna Eliza Maciel de Faria Mota Oliveira,
• Rafael Miguel Sábio,
• Gabriel Davi Marena,
• Tais Maria Bauab,
• Cristiane Duque,
• Vincent Corbel and
• Marlus Chorilli

Beilstein J. Nanotechnol. 2024, 15, 104–114, doi:10.3762/bjnano.15.10

• the release of cymene and myrcene from the nanoemulsions was performed at specific time intervals: 30 min and 1, 2, 4, 6, 8, 12, and 24 h. Each measurement was repeated six times to ensure reliability. The released compounds were quantified by high-performance liquid chromatography, following a

Nanostructured lipid carriers containing benznidazole: physicochemical, biopharmaceutical and cellular in vitro studies

• Giuliana Muraca,
• María Esperanza Ruiz,
• Rocío C. Gambaro,
• Sebastián Scioli-Montoto,
• María Laura Sbaraglini,
• Gisel Padula,
• José Sebastián Cisneros,
• Cecilia Yamil Chain,
• Vera A. Álvarez,
• Cristián Huck-Iriart,
• Guillermo R. Castro,
• María Belén Piñero,
• Matias Ildebrando Marchetto,
• Catalina Alba Soto,
• Germán A. Islan and
• Alan Talevi

Beilstein J. Nanotechnol. 2023, 14, 804–818, doi:10.3762/bjnano.14.66

• was estimated by performing a high-performance liquid chromatography (HPLC) analysis of the filtrate. Considering the initial amount of BNZ added to the formulation, the EE% was calculated as follows: where M0 is the initial amount of BNZ added to the formulation, Cfree is the drug concentration of

Metal-organic framework-based nanomaterials as opto-electrochemical sensors for the detection of antibiotics and hormones: A review

• Akeem Adeyemi Oladipo,
• Saba Derakhshan Oskouei and
• Mustafa Gazi

Beilstein J. Nanotechnol. 2023, 14, 631–673, doi:10.3762/bjnano.14.52

• spectrometry (LC–MS), high-performance liquid chromatography (HPLC), and gas chromatography coupled with mass spectrometry (GC–MS) have demonstrated greater selectivity and lower variability when compared to immunoassays for the measurement of antibiotics and steroid hormones in various complex samples [22][23

Non-stoichiometric magnetite as catalyst for the photocatalytic degradation of phenol and 2,6-dibromo-4-methylphenol – a new approach in water treatment

• Joanna Kisała,
• Anna Tomaszewska and
• Przemysław Kolek

Beilstein J. Nanotechnol. 2022, 13, 1531–1540, doi:10.3762/bjnano.13.126

• up to 1h). The organic compound concentrations were evaluated by using HPLC. Analysis Changes in phenol concentration were determined by a high-performance liquid chromatography system (Shimadzu, Japan) equipped with a UV detector (SPD-10AV) and a C18 column (Knauer 250 × 4.6 mm, Eurospher II 100-5

Design of surface nanostructures for chirality sensing based on quartz crystal microbalance

• Yinglin Ma,
• Xiangyun Xiao and
• Qingmin Ji

Beilstein J. Nanotechnol. 2022, 13, 1201–1219, doi:10.3762/bjnano.13.100

• resonance [10], Fourier transform infrared spectrometry (FTIR) [11], UV–vis absorption spectrometry [12], mass spectrometry (MS) [13], titration microcalorimetry [14], high-performance liquid chromatography (HPLC) [15], gas chromatography (GC), capillary electrophoresis (CE) [16], and electrochemical chiral

Ethosomal (−)-epigallocatechin-3-gallate as a novel approach to enhance antioxidant, anti-collagenase and anti-elastase effects

• Çiğdem Yücel,
• Gökçe Şeker Karatoprak,
• Sena Yalçıntaş and
• Tuğba Eren Böncü

Beilstein J. Nanotechnol. 2022, 13, 491–502, doi:10.3762/bjnano.13.41

• liquid chromatography assay For the quantitative determination of EGCG, the optimal wavelength of 292 nm was used. The calibration curve obtained from high-performance liquid chromatography (HPLC) was linear between 15.625 to 1000 µg/mL with a high correlation coefficient (y = 1.0548x + 4.7737, r2

• activity of the active compound with appropriate formulations and determining its inhibitory effects on elastase and collagenase enzymes, which accelerate the aging process in the skin, and our findings provide a novel and important contribution to the literature. Results and Discussion High-performance

Engineered superparamagnetic iron oxide nanoparticles (SPIONs) for dual-modality imaging of intracranial glioblastoma via EGFRvIII targeting

• Xianping Liu,
• Chengjuan Du,
• Haichun Li,
• Ting Jiang,
• Zimiao Luo,
• Zhiqing Pang,
• Daoying Geng and
• Jun Zhang

Beilstein J. Nanotechnol. 2019, 10, 1860–1872, doi:10.3762/bjnano.10.181

• . To analyze the concentration of peptide in the supernatant, high-performance liquid chromatography (HPLC) (Agilent 1200, USA) was used, where the mixture of solvent A and solvent B (59/41, v/v) was used as the mobile phase. Solvent A was 0.1% trifluoroacetic acid dissolved in deionized water and

• the NP zeta potential confirmed the successful conjugation of the positive-valued targeting peptide PEPHC1 (Figure 1d). High-performance liquid chromatography (HPLC) determination (results not shown) further supported the successful conjugation of PEPHC1 where the conjugation efficiency of the PEPHC1

Lipid nanostructures for antioxidant delivery: a comparative preformulation study

• Elisabetta Esposito,
• Maddalena Sguizzato,
• Markus Drechsler,
• Paolo Mariani,
• Federica Carducci,
• Claudio Nastruzzi,
• Giuseppe Valacchi and
• Rita Cortesi

Beilstein J. Nanotechnol. 2019, 10, 1789–1801, doi:10.3762/bjnano.10.174

• and RA content was analyzed after filtration by high-performance liquid chromatography (HPLC) using a Knauer Eurospher II RP C18 column (Knauer, Germany) (15 × 0.4 cm) stainless steel packed with 5 µm particles, eluted at room temperature with different mobile phases. Samples of 50 µL were injected

Doxorubicin-loaded human serum albumin nanoparticles overcome transporter-mediated drug resistance in drug-adapted cancer cells

• Hannah Onafuye,
• Sebastian Pieper,
• Dennis Mulac,
• Jindrich Cinatl Jr.,
• Mark N. Wass,
• Klaus Langer and
• Martin Michaelis

Beilstein J. Nanotechnol. 2019, 10, 1707–1715, doi:10.3762/bjnano.10.166

• supernatants were collected and the drug content was measured by high-performance liquid chromatography (HPLC) as described below. The loading efficiency of doxorubicin in the nanoparticles was calculated based on the difference between the doxorubicin amount used for nanoparticle preparation and the unbound

Nanoporous smartPearls for dermal application – Identification of optimal silica types and a scalable production process as prerequisites for marketed products

• David Hespeler,
• Sanaa El Nomeiri,
• Jonas Kaltenbach and
• Rainer H. Müller

Beilstein J. Nanotechnol. 2019, 10, 1666–1678, doi:10.3762/bjnano.10.162

• ” (version 2.21). High-performance liquid chromatography (HPLC) measurements of the same samples were performed at 25 °C using a Kontron 400 system (Kontron Instruments GmbH, Germany) equipped with a 20 µL loop and a Eurosper 100-5 C18 column (250 × 4 mm, 5 µm particle size) column. Determination was

Structural and optical properties of penicillamine-protected gold nanocluster fractions separated by sequential size-selective fractionation

• Xiupei Yang,
• Zhengli Yang,
• Fenglin Tang,
• Jing Xu,
• Maoxue Zhang and
• Martin M. F. Choi

Beilstein J. Nanotechnol. 2019, 10, 955–966, doi:10.3762/bjnano.10.96

• (CE) and high-performance liquid chromatography (HPLC), this limitation can be overcome to some extent by reducing the surface effects of the separation system. The capacity for each run of these two methods (micrograms for HPLC and nanograms for capillary zone electrophoresis (CZE)) have hindered

Ag₂WO₄ nanorods decorated with AgI nanoparticles: Novel and efficient visible-light-driven photocatalysts for the degradation of water pollutants

• Shijie Li,
• Shiwei Hu,
• Wei Jiang,
• Yanping Liu,
• Yu Liu,
• Yingtang Zhou,
• Liuye Mo and
• Jianshe Liu

Beilstein J. Nanotechnol. 2018, 9, 1308–1316, doi:10.3762/bjnano.9.123

• concentrations were monitored by high-performance liquid chromatography (HPLC, Agilent 110 series). The total organic carbon (TOC) experiment was carried out by dispersing 100 mg of 0.3AgI/Ag2WO4 in RhB (50 mg L–1, 100 mL) solution. During the reaction, a 10 mL suspension was sampled every hour and monitored by

Colloidal solution of silver nanoparticles for label-free colorimetric sensing of ammonia in aqueous solutions

• Alessandro Buccolieri,
• Antonio Serra,
• Gabriele Giancane and
• Daniela Manno

Beilstein J. Nanotechnol. 2018, 9, 499–507, doi:10.3762/bjnano.9.48

• analysis [8], gas chromatography [9], immunoassays [10], thin-layer chromatography [11], high-performance liquid chromatography (HPLC) [12] are the main methods used so far for a reliable determination of NH3 levels. However, the above-mentioned techniques have difficulties and disadvantages, such as the

Influence of the preparation method on the photocatalytic activity of Nd-modified TiO₂

• Patrycja Parnicka,
• Paweł Mazierski,
• Tomasz Grzyb,
• Wojciech Lisowski,
• Ewa Kowalska,
• Bunsho Ohtani,
• Adriana Zaleska-Medynska and
• Joanna Nadolna

Beilstein J. Nanotechnol. 2018, 9, 447–459, doi:10.3762/bjnano.9.43

• stripping process). Samples of 0.5 mL reaction mixture were collected after regular time periods during irradiation and filtered through syringe filters (diameter 0.2 μm) to remove the suspended photocatalyst particles. Kinetics of phenol degradation were determined by high-performance liquid chromatography