Rational design of block copolymer self-assemblies in photodynamic therapy

• Maxime Demazeau,
• Laure Gibot,
• Anne-Françoise Mingotaud,
• Patricia Vicendo,
• Clément Roux and
• Barbara Lonetti

Beilstein J. Nanotechnol. 2020, 11, 180–212, doi:10.3762/bjnano.11.15

Molecular architectonics of DNA for functional nanoarchitectures

• Debasis Ghosh,
• Lakshmi P. Datta and
• Thimmaiah Govindaraju

Beilstein J. Nanotechnol. 2020, 11, 124–140, doi:10.3762/bjnano.11.11

• scaffold embedded with Ru(bpy)32+-conjugated silica nanoparticles. The DNA tetrahedron geometry acted as a capture DNA that repelled the nonspecific DNA entanglement along the ECL platform and stimulated the hybridization of glucose oxidase (GOD) enzyme-conjugated DNA (GOD-S). In a programmable cyclic

• amplification pathway, the target DNA triggered the release of GOD-S that catalyzed glucose to form hydrogen peroxide, followed by changing the ECL signal. The ECL sensing solution was made up of tripropylamine (TPrA) and glucose (10 mM). The concentration of target DNA could easily be assessed by quantifying

Simple synthesis of nanosheets of rGO and nitrogenated rGO

• Pallellappa Chithaiah,
• Madhan Mohan Raju,
• Giridhar U. Kulkarni and
• C. N. R. Rao

Beilstein J. Nanotechnol. 2020, 11, 68–75, doi:10.3762/bjnano.11.7

• has been developed to obtain rGO through the reduction of exfoliated GO using various reducing agents such as hydrazine or dimethylhydrazine [21], NaBH4 [22], hydroquinone [23], or glucose [24]. However, these methods have not yet turned into a global strategy to prepare pure rGO in a scalable fashion

• , respectively, with their lateral dimension in the range of several hundred nanometers. The experimental process and the digital photographs of rGO and N-rGO products are shown in Figure 7. Sucrose consists of one molecule of glucose and one molecule of fructose. The sucrose molecule contains –OH, -CH2OH, and

Synthesis of amorphous and graphitized porous nitrogen-doped carbon spheres as oxygen reduction reaction catalysts

• Maximilian Wassner,
• Markus Eckardt,
• Andreas Reyer,
• Thomas Diemant,
• Michael S. Elsaesser,
• R. Jürgen Behm and
• Nicola Hüsing

Beilstein J. Nanotechnol. 2020, 11, 1–15, doi:10.3762/bjnano.11.1

• synthesized by hydrothermal treatment of a glucose solution yielding carbon spheres with sizes of 330 ± 50 nm, followed by nitrogen doping via heat treatment in ammonia atmosphere. The influence of a) varying the nitrogen doping temperature (550–1000 °C) and b) of a catalytic graphitization prior to nitrogen

• properties and of the ORR activity and mechanism is given elsewhere [27]. Results and Discussion 1 Synthesis and structural/chemical analysis of (graphitized) N-doped carbon spheres Carbon spheres were synthesized by hydrothermal treatment of a glucose solution (Figure 1), following a previously reported

• is needed, however, to improve the relative high peroxide yields obtained so far. Conclusion The N-doped carbon spheres (NCS) synthesized in the present work are characterized by a well-defined spherical shape and smooth surface. Originating from glucose, the carbon matrix of the spheres initially

The different ways to chitosan/hyaluronic acid nanoparticles: templated vs direct complexation. Influence of particle preparation on morphology, cell uptake and silencing efficiency

• Arianna Gennari,
• Julio M. Rios de la Rosa,
• Erwin Hohn,
• Maria Pelliccia,
• Enrique Lallana,
• Roberto Donno,
• Annalisa Tirella and
• Nicola Tirelli

Beilstein J. Nanotechnol. 2019, 10, 2594–2608, doi:10.3762/bjnano.10.250

• performing better in macrophages and those with high-MW chitosan in HCT-116. Keywords: aggregation; chitosan; field flow fractionation; light scattering; targeted drug delivery; Introduction Chitosan is a linear copolymer of β-1,4-ᴅ-glucose-2-amine and N-acetyl-ᴅ-glucose-2-amine, and is commonly employed

• images were analysed using ImageJ software (v1.49p, http://rsb.info.nih.gov/ij). Cell studies HCT-116 and RAW 264.7 cell lines were cultured in complete media (McCoy’s 5A or high glucose DMEM, respectively) under standard conditions for cell culture (5% v/v CO2 in air, 37 °C). Further details of the

Small protein sequences can induce cellular uptake of complex nanohybrids

• Jan-Philip Merkl,
• Malak Safi,
• Christian Schmidtke,
• Fadi Aldeek,
• Johannes Ostermann,
• Tatiana Domitrovic,
• Sebastian Gärtner,
• John E. Johnson,
• Horst Weller and
• Hedi Mattoussi

Beilstein J. Nanotechnol. 2019, 10, 2477–2482, doi:10.3762/bjnano.10.238

• . In one study, Jana and co-workers reported the design of fluorescent and plasmonic nanohybrids by covalent attachment of luminescent quantum dots (QDs) and Au nanorods. Further functionalization with glucose, using glutaraldehyde coupling chemistry, yielded nanohybrids that could subsequently be used

Design of a nanostructured mucoadhesive system containing curcumin for buccal application: from physicochemical to biological aspects

• Sabrina Barbosa de Souza Ferreira,
• Gustavo Braga,
• Évelin Lemos Oliveira,
• Jéssica Bassi da Silva,
• Hélen Cássia Rosseto,
• Lidiane Vizioli de Castro Hoshino,
• Mauro Luciano Baesso,
• Wilker Caetano,
• Craig Murdoch,
• Helen Elizabeth Colley and
• Marcos Luciano Bruschi

Beilstein J. Nanotechnol. 2019, 10, 2304–2328, doi:10.3762/bjnano.10.222

• ), sodium chloride was purchased from Nuclear (Diadema, SP, Brazil) and polyssorbate 80 (Tween 80®) came from Synth® (Diadema, SP, Brazil). Dulbecco’s Modified Eagle’s Medium high glucose (DMEM), fetal bovine serum (FBS), ʟ-glutamine, penicillin, streptomycin and trypsin

Design and facile synthesis of defect-rich C-MoS₂/rGO nanosheets for enhanced lithium–sulfur battery performance

• Chengxiang Tian,
• Juwei Wu,
• Zheng Ma,
• Bo Li,
• Pengcheng Li,
• Xiaotao Zu and
• Xia Xiang

Beilstein J. Nanotechnol. 2019, 10, 2251–2260, doi:10.3762/bjnano.10.217

• nanosheets For the synthesis of the C-MoS2/rGO nanosheets, 1.23 g hexaammonium heptamolybdate tetrahydrate, 0.89 g of glucose, and 2.28 g thiourea were dissolved in 25 mL of deionized water to form solution A; 0.03 g of GO was dissolved into 10 mL of deionized water by ultrasonic to form solution B. Then

• 60 °C in vacuum. For comparison, the pristine MoS2 were synthesized using an identical process without GO or glucose. After that, the obtained composites were annealed at 400, 600 and 800 °C for 6 h in 10% H2/Ar atmosphere to improve the crystallinity. After thermal annealing, the samples were

• [33]. The peaks located at 285.1 and 286.2 eV correspond to the binding energy of carbon in C–C bonds and C–O bonds, respectively, owing to an amorphous carbon layer originated from glucose. The two weak peaks originating from C–O and C=O bonds illustrate that the oxygen-containing functional groups

Mannosylated brush copolymers based on poly(ethylene glycol) and poly(ε-caprolactone) as multivalent lectin-binding nanomaterials

• Stefania Ordanini,
• Wanda Celentano,
• Anna Bernardi and
• Francesco Cellesi

Beilstein J. Nanotechnol. 2019, 10, 2192–2206, doi:10.3762/bjnano.10.212

• -functionalized monomer, starting from a four-arm initiator based on poly(ε-caprolactone), led to a library of glucose-functionalized aggregates able to bind the glucose- and mannose-binding lectin Concanavalin A (Con A) [12]. The combination of ATRP of protected alkyne monomers and a copper-catalyzed azide

Use of data processing for rapid detection of the prostate-specific antigen biomarker using immunomagnetic sandwich-type sensors

• Camila A. Proença,
• Tayane A. Freitas,
• Thaísa A. Baldo,
• Elsa M. Materón,
• Flávio M. Shimizu,
• Gabriella R. Ferreira,
• Frederico L. F. Soares,
• Ronaldo C. Faria and
• Osvaldo N. Oliveira Jr.

Beilstein J. Nanotechnol. 2019, 10, 2171–2181, doi:10.3762/bjnano.10.210

• Prussian blue (PB) interlayer and a gold shell. The enzymes horseradish peroxidase and glucose oxidase were immobilized to improve sensitivity, with linear ranges between 0.01 and 80.0 ng·mL−1 for CEA and from 0.014 to 142 ng·mL−1 for AFP, and detection limits of 4 pg·mL−1 and 7 pg·mL−1, respectively [25

Improved adsorption and degradation performance by S-doping of (001)-TiO₂

• Xiao-Yu Sun,
• Xian Zhang,
• Xiao Sun,
• Ni-Xian Qian,
• Min Wang and
• Yong-Qing Ma

Beilstein J. Nanotechnol. 2019, 10, 2116–2127, doi:10.3762/bjnano.10.206

• performance. Li et al. synthesized composites of mesoporous (001)-TiO2 and C applying a one-pot hydrothermal strategy in the presence of glucose and hydrofluoric acid (HF). The composites an exhibited excellent visible-light-driven photocatalytic performance [14]. Chen et al. synthesized a composite of g-C3N4

Review of advanced sensor devices employing nanoarchitectonics concepts

• Katsuhiko Ariga,
• Tatsuyuki Makita,
• Masato Ito,
• Taizo Mori,
• Shun Watanabe and
• Jun Takeya

Beilstein J. Nanotechnol. 2019, 10, 2014–2030, doi:10.3762/bjnano.10.198

• mechanically controlled indicator displacement assay for aqueous glucose detection based on fluorescence resonance energy transfer was also reported [180]. The mechanisms of molecular recognition and sensing are roughly summarized in Figure 9. The most basic mechanism (Figure 9) is considered to form the most

Optimization and performance of nitrogen-doped carbon dots as a color conversion layer for white-LED applications

• Tugrul Guner,
• Hurriyet Yuce,
• Didem Tascioglu,
• Eren Simsek,
• Umut Savaci,
• Aziz Genc,
• Servet Turan and
• Mustafa M. Demir

Beilstein J. Nanotechnol. 2019, 10, 2004–2013, doi:10.3762/bjnano.10.197

• using glucose and polyethylene glycol 200. It is reported that the WLED showed a superior performance indicated by Commission Internationale de l'Éclairage (CIE) coordinates of (0.32, 0.37) and a CCT of 5584 K. In another study, Joseph et al. reported the synthesis of CDots by the electrochemical

Gold-coated plant virus as computed tomography imaging contrast agent

• Alaa A. A. Aljabali,
• Mazhar S. Al Zoubi,
• Khalid M. Al-Batanyeh,
• Ali Al-Radaideh,
• Mohammad A. Obeid,
• Abeer Al Sharabi,
• Walhan Alshaer,
• Bayan AbuFares,
• Tasnim Al-Zanati,
• Murtaza M. Tambuwala,
• Naveed Akbar and
• David J. Evans

Beilstein J. Nanotechnol. 2019, 10, 1983–1993, doi:10.3762/bjnano.10.195

• -hydroxysulfosuccinimide (sulfo-NHS), bicinchoninic acid (BCA) protein assay kit, RPMI, foetal calf serum, and T125 mm tissue culture flasks were purchased from ThermoFisher Scientific; EGM-2 medium was purchased from Lonza. Cell culture medium phenol red-free (high-glucose Dulbecco modified eagle medium (DMEM

Engineered superparamagnetic iron oxide nanoparticles (SPIONs) for dual-modality imaging of intracranial glioblastoma via EGFRvIII targeting

• Xianping Liu,
• Chengjuan Du,
• Haichun Li,
• Ting Jiang,
• Zimiao Luo,
• Zhiqing Pang,
• Daoying Geng and
• Jun Zhang

Beilstein J. Nanotechnol. 2019, 10, 1860–1872, doi:10.3762/bjnano.10.181

• Sigma (USA) and Cy7.5 NHS ester was purchased from Nanocs (USA). Fetal bovine serum (FBS), phosphate buffered saline (PBS), trypsin-EDTA (0.25%), high glucose Dulbecco’s modified Eagle’s medium (DMEM) and penicillin-streptomycin were purchased from Gibco (CA, USA). The MTT cell proliferation and

Biocatalytic oligomerization-induced self-assembly of crystalline cellulose oligomers into nanoribbon networks assisted by organic solvents

• Yuuki Hata,
• Yuka Fukaya,
• Toshiki Sawada,
• Masahito Nishiura and
• Takeshi Serizawa

Beilstein J. Nanotechnol. 2019, 10, 1778–1788, doi:10.3762/bjnano.10.173

• self-assembly of cellulose oligomers into hierarchical nanoribbon network structures. In this study, we dealt with the cellodextrin phosphorylase-catalyzed oligomerization of phosphorylated glucose monomers from ᴅ-glucose primers, which produce precipitates of nanosheet-shaped crystals in aqueous

• ][28]. For example, the cellulase-catalyzed oligomerization of β-ᴅ-cellobiosyl fluoride monomers [29] and the cellodextrin phosphorylase (CDP)-catalyzed oligomerization of α-ᴅ-glucose 1-phosphate (αG1P) monomers from ᴅ-glucose [30][31] and cellobiose [32][33] primers have been demonstrated, where the

• been successfully synthesized by using glucose derivatives as primers for the CDP-catalyzed oligomerization. By exploiting those enzyme-catalyzed oligomerization systems, various nanostructures, including nanofibrous assemblies [41], rectangular nanosheet-shaped lamellar crystals [30][31][39][42

Materials nanoarchitectonics at two-dimensional liquid interfaces

• Katsuhiko Ariga,
• Michio Matsumoto,
• Taizo Mori and
• Lok Kumar Shrestha

Beilstein J. Nanotechnol. 2019, 10, 1559–1587, doi:10.3762/bjnano.10.153

• changes of the molecular machines, for instance, to capture and release guest molecules [167][168], to rotate of molecular rotors [169][170], to open and close molecular pliers [171][172], or in indicator displacement assays of glucose based on fluorescence resonance energy transfer [173]. Subtle

Multicomponent bionanocomposites based on clay nanoarchitectures for electrochemical devices

• Giulia Lo Dico,
• Bernd Wicklein,
• Lorenzo Lisuzzo,
• Giuseppe Lazzara,
• Pilar Aranda and
• Eduardo Ruiz-Hitzky

Beilstein J. Nanotechnol. 2019, 10, 1303–1315, doi:10.3762/bjnano.10.129

• glucose oxidase (GOx) into the lumen of HNTs has been chosen here as an example for the immobilization of bioactive species, which can be crucial to design (bio)electrochemical devices with high performance and long life-time. The SEP, GNP, and MWCNT components are also expected to behave as polymer

• ]. The resulting multicomponent systems have advantages such as high electrical conductivity and flexibility that make the bionanocomposite films appropriate components for biosensors [35][40] for glucose detection, while the relatively high porosity of the bioactive foams enhances the power density and

• material in aqueous media. Moreover, the successful incorporation of HNTs as nanoreactor prompted the use of these bionanocomposite materials in bioelectrocatalysis applications (see below). Immobilization of glucose oxidase in the lumen of HNTs The developed multicomponent bionanocomposites were used for

A silver-nanoparticle/cellulose-nanofiber composite as a highly effective substrate for surface-enhanced Raman spectroscopy

• Yongxin Lu,
• Yan Luo,
• Zehao Lin and
• Jianguo Huang

Beilstein J. Nanotechnol. 2019, 10, 1270–1279, doi:10.3762/bjnano.10.126

• Silver nitrate (AgNO3), β-ᴅ-glucose and concentrated ammonia were bought from Sinopharm Chemical Reagent Co., Ltd. (Shanghai, China); sodium hydrate (NaOH) was purchased from Shanghai Titanchem Co., Ltd. (Shanghai, China); Rhodamine 6G (R6G, 98.5%) was obtained from J&K Chemical Ltd. (Shanghai, China

• solution was added dropwise under swift stirring into the mixture until the precipitate dissolved. Then, 15.0 mL of aqueous β-ᴅ-glucose solution (10 wt %) was added into the prepared Tollens’ reagent under continuous stirring. The solution obtained was immediately poured into a Petri dish where 5 pieces of

Glucose-derived carbon materials with tailored properties as electrocatalysts for the oxygen reduction reaction

• Rafael Gomes Morais,
• Natalia Rey-Raap,
• José Luís Figueiredo and
• Manuel Fernando Ribeiro Pereira

Beilstein J. Nanotechnol. 2019, 10, 1089–1102, doi:10.3762/bjnano.10.109

• -doped biomass-derived carbon materials were prepared by hydrothermal carbonization of glucose, and their textural and chemical properties were subsequently tailored to achieve materials with enhanced electrochemical performance towards the oxygen reduction reaction. Carbonization and physical activation

• biomass-derived carbons. Therefore, this study aims to prepare glucose-derived carbon materials with different textural and chemical properties and to correlate these properties with the performance towards ORR. Activated carbons with different microporosity were prepared by activating the samples at

• the performance of glucose-derived activated carbons, the surface chemistry of the sample AG6h (from now on simply named AG) was modified by applying different doping methods: ball milling and conventional mixing. In addition, such methods were also applied to a carbonized sample to evaluate the

Scavenging of reactive oxygen species by phenolic compound-modified maghemite nanoparticles

• Małgorzata Świętek,
• Yi-Chin Lu,
• Rafał Konefał,
• Liliana P. Ferreira,
• M. Margarida Cruz,
• Yunn-Hwa Ma and
• Daniel Horák

Beilstein J. Nanotechnol. 2019, 10, 1073–1088, doi:10.3762/bjnano.10.108

• phenolic compounds and allow for the attachment of the cationic polymer (chitosan). Heparin is a polysaccharide, containing glycosaminoglycan with densely repeated O-(α-L-iodopyranosyluric acid 2-sulfate)-(1→4)-2-sulfoamino-2-deoxy-D-glucose 6-sulfate sequences obtained from the mucosal tissue of animals

The systemic effect of PEG-nGO-induced oxidative stress in vivo in a rodent model

• Qura Tul Ain,
• Samina Hyder Haq,
• Abeer Alshammari,
• Moudhi Abdullah Al-Mutlaq and
• Muhammad Naeem Anjum

Beilstein J. Nanotechnol. 2019, 10, 901–911, doi:10.3762/bjnano.10.91

• activity of GO [17]. Moreover, GO-based sensors have been used for the detection of neonicotinoids [18], tyrosine [19], ascorbic acid, dopamine, uric acid [20], 4-nitrophenol [21], and glucose [22]. Among all biocompatible polymers, PEG has been extensively used as a GO cover. Feng et al. used PEG and PEI

Features and advantages of flexible silicon nanowires for SERS applications

• Hrvoje Gebavi,
• Vlatko Gašparić,
• Dubravko Risović,
• Nikola Baran,
• Paweł Henryk Albrycht and
• Mile Ivanda

Beilstein J. Nanotechnol. 2019, 10, 725–734, doi:10.3762/bjnano.10.72

• -sensitive and has a relatively large Raman cross section (ca. 10−29 cm2/sr [28]). The boronic acid group binds to certain analytes, for example, peptidoglycans in bacterial cell walls [29]. Recently, the difficult detection of saccharides (glucose, fructose) due to a low Raman scattering cross-section and a

Thermal control of the defunctionalization of supported Au₂₅(glutathione)₁₈ catalysts for benzyl alcohol oxidation

• Zahraa Shahin,
• Hyewon Ji,
• Rodica Chiriac,
• Nadine Essayem,
• Franck Rataboul and
• Aude Demessence

Beilstein J. Nanotechnol. 2019, 10, 228–237, doi:10.3762/bjnano.10.21

• activated carbon (AC) exhibited high efficiency in glucose oxidation [25]. The full defunctionalization at higher temperature usually induces an increase in particle size and decrease of the catalytic activity [26]. Benzyl alcohol oxidation is a model reaction generally used to test the catalytic activity

Comparative biological effects of spherical noble metal nanoparticles (Rh, Pd, Ag, Pt, Au) with 4–8 nm diameter

• Alexander Rostek,
• Marina Breisch,
• Kevin Pappert,
• Kateryna Loza,
• Marc Heggen,
• Manfred Köller,
• Christina Sengstock and
• Matthias Epple

Beilstein J. Nanotechnol. 2018, 9, 2763–2774, doi:10.3762/bjnano.9.258

• = 40,000 g mol−1), sodium borohydride (Sigma-Aldrich, ≥96%, p.a.) trisodium citrate (Acros, anhydrous 98%), tannic acid (Fluka, p.a.), and D-glucose (Baker, p.a.) were all used as obtained. Aqueous solutions of H2PtCl6 or HAuCl4 (prepared by dissolution of platinum or gold in aqua regia), RhCl3, NaPdCl4

• nanoparticles: In a 100 mL two-neck round-bottom flask, 600 mg D-glucose and 50 mg PVP were dissolved in 50 mL water under stirring and heated to 100 °C under reflux. Then an aqueous solution (5 mL) of the corresponding metal precursor (25 µmol for Pt and 50 µmol for Rh and Pd) was rapidly added. The mixture

• diameter between 4 and 8 nm by different syntheses that are colloidally stabilized by PVP. Rhodium, palladium, and platinum were reduced with glucose, silver was reduced with NaBH4, and gold was reduced with a mixture of citrate and tannine. The particles were characterized by dynamic light scattering (DLS