Deep-learning recognition and tracking of individual nanotubes in low-contrast microscopy videos

• Vladimir Pimonov,
• Said Tahir and
• Vincent Jourdain

Beilstein J. Nanotechnol. 2025, 16, 1316–1324, doi:10.3762/bjnano.16.96

• , augmentations were applied to account for possible variations in image brightness, contrast, and nanotube localization (Supporting Information File 1, Figure S4). This approach not only expanded the dataset without additional manual labeling but also increased the robustness and stability of the trained model

• labeling the dataset used to train the DL model, allowing for comparison of data obtained by both methods to validate their coherence. Properly designed training datasets and augmentations improve model robustness and stability without increasing training data volume. Despite significant advancements

Enhancing the photoelectrochemical performance of BiOI-derived BiVO₄ films by controlled-intensity current electrodeposition

• Huu Phuc Dang,
• Khanh Quang Nguyen,
• Nguyen Thi Mai Tho and
• Tran Le

Beilstein J. Nanotechnol. 2025, 16, 1289–1301, doi:10.3762/bjnano.16.94

• limited by material challenges, including insufficient light absorption, high electron–hole recombination rates, and poor stability under operating conditions [5][6]. Among various semiconductor materials, bismuth vanadate (BiVO4) has attracted considerable interest due to its strong visible light

• absorption, moderate bandgap (≈2.4 eV), high theoretical photocurrent density (≈7.5 mA·cm−2), and chemical stability in aqueous environments [7][8][9]. Nevertheless, BiVO4 suffers from intrinsic drawbacks such as low charge carrier mobility, limited conductivity, and rapid recombination of photogenerated

• , as well as the reduced electron–hole recombination rates observed in the Raman and UV–vis analyses. The long-term photoelectrochemical stability of the optimized BiVO4(326) photoanode was evaluated using chronoamperometry under continuous AM1.5G illumination at 1.23 V vs RHE in 0.50 M Na2SO4

Acrocomia aculeata oil-loaded nanoemulsion: development, anti-inflammatory properties, and cytotoxicity evaluation

• Verónica Bautista-Robles,
• Hady Keita,
• Edgar Julián Paredes Gamero,
• Layna Tayná Brito Leite,
• Jessica de Araújo Isaías Muller,
• Mônica Cristina Toffoli Kadri,
• Ariadna Lafourcade Prada and
• Jesús Rafael Rodríguez Amado

Beilstein J. Nanotechnol. 2025, 16, 1277–1288, doi:10.3762/bjnano.16.93

• , nutraceutical, and industrial applications. However, due to the chemical and physicochemical characteristics as well as the solubility and stability of this oil, it was decided to make a nanoemulsion to enhance its already known therapeutic benefits. Nanoemulsions are nanoemulsified systems, either oil-in-water

• (O/W) or water-in-oil (W/O), which are isotropic, homogeneous, and thermodynamically unstable, with droplet sizes ranging from 20 to 200 nm [20]. They present properties such as high surface area per unit volume, robust kinetic stability, and tunable rheology [21]. It has been demonstrated that

• presence of phenols and carotenoids, which were characterized in this study. These secondary metabolites are considered to have high antioxidant activity and provide high stability to the oil [5]. These metabolites have been shown to possess anti-inflammatory and immunostimulant properties [1][33

Better together: biomimetic nanomedicines for high performance tumor therapy

• Imran Shair Mohammad,
• Gizem Kursunluoglu,
• Anup Kumar Patel,
• Hafiz Muhammad Ishaq,
• Cansu Umran Tunc,
• Dilek Kanarya,
• Mubashar Rehman,
• Omer Aydin and
• Yin Lifang

Beilstein J. Nanotechnol. 2025, 16, 1246–1276, doi:10.3762/bjnano.16.92

• . BSA has some immunogenic effects and is therefore used in immunotherapy and analytic bioassay applications [78][81][82][83]. 1.3.3 Human serum albumin. Human serum albumin (HSA) has biomedical applications as HAS-templated NPs exhibit immune escape, enhanced stability, and high drug loading [84][85

• “disassembly–reassembly” technology to obtain reconstituted RBCs (rRBCs) for a membrane-coated delivery platform. It was found that the rRBC membrane improved stability, circulation time, and immune escape after removing the endogenous proteins and lipids on the membrane. After synthesizing biomimetic rRBC

Functional bio-packaging enhanced with nanocellulose from rice straw and cinnamon essential oil Pickering emulsion for fruit preservation

• Tuyen B. Ly,
• Duong D. T. Nguyen,
• Hieu D. Nguyen,
• Yen T. H. Nguyen,
• Bup T. A. Bui,
• Kien A. Le and
• Phung K. Le

Beilstein J. Nanotechnol. 2025, 16, 1234–1245, doi:10.3762/bjnano.16.91

• matrix properties, including tensile strength, elasticity, and thermal stability, due to its high surface area, hydroxy groups forming hydrogen bonds, and excellent dispersion within the matrix [20][21]. This improvement is attributed to interaction between hydroxy groups in NC and PVA, effectively

• dispersibility of essential oils in biopolymer matrices but also enhances the overall compatibility and performance of the biopackaging material [22]. Our previous research has demonstrated that nanocellulose can effectively encapsulate CEO into a PE with small particle sizes (<700 nm), high stability, and

• release [42]. At temperatures above 380 °C, carbonaceous residues decomposed. The addition of NC shifted the degradation onset temperature to a higher range, indicating improved thermal stability. This could be due to the rigid nature of NC particles, which enhance the structural integrity of the

Hydrogels and nanogels: effectiveness in dermal applications

• Jéssica da Cruz Ludwig,
• Diana Fortkamp Grigoletto,
• Daniele Fernanda Renzi,
• Wolf-Rainer Abraham,
• Daniel de Paula and
• Najeh Maissar Khalil

Beilstein J. Nanotechnol. 2025, 16, 1216–1233, doi:10.3762/bjnano.16.90

• stability, absorption, and biodistribution impairments. Among the DDSs, we can highlight hydrogels and nanogels, which are easy to obtain, show good biocompatibility, and have several applications in the design of drug carriers for dermal and ocular administration. In this review, we introduce a brief

• properties to a gel previously composed of a more rigid and brittle network, a double network gel with an IPN structure is obtained. This approach significantly contributes to improving the mechanical properties and stability of the system [43][52]. Synthetic polymers, including acrylates [53], acrylamide

• amine (NH2) and hydroxyl (OH) functional groups [77], as shown in Figure 1. The stability of hydrogels is maintained by cross-links that, in aqueous media, prevent the dissolution of polymer chains [134]. Another polymer widely used in the preparation of hydrogels is cellulose. Cellulose hydrogels have

Investigation of the solubility of protoporphyrin IX in aqueous and hydroalcoholic solvent systems

• Michelly de Sá Matsuoka,
• Giovanna Carla Cadini Ruiz,
• Marcos Luciano Bruschi and
• Jéssica Bassi da Silva

Beilstein J. Nanotechnol. 2025, 16, 1209–1215, doi:10.3762/bjnano.16.89

• aggregation, and improve bioavailability in aqueous media [5][16]. Additionally, at high concentrations, P407 can transition into more complex nanostructured systems, such as hydrogels and lyotropic liquid crystals, providing additional control over drug release and stability. The thermosensitive and self

• solubility and stability for hydrophobic compounds. In systems containing 10% (w/w) P407 with 0.4 mg/mL PpIX (EtOH50, EtOH77, and water), the complete solubilization was achieved regardless of the solvent used. Figure 4 shows the solubilization kinetics in the polymeric systems. The average concentrations

• favorable behavior, as no micellar disintegration was observed, unlike the systems containing ethanol. These findings are consistent with other experimental results, reinforcing the stability and solubilizing potential of aqueous micellar systems for PpIX [8]. To improve the assessment of solubility

Chitosan nanocomposite containing rotenoids: an alternative bioinsecticidal approach for the management of Aedes aegypti

• Maria A. A. Bertonceli,
• Vitor D. C. Cristo,
• Ivo J. Vieira,
• Francisco J. A. Lemos,
• Arnoldo R. Façanha,
• Raimundo Braz-Filho,
• Gustavo V. T. Batista,
• Luis G. M. Basso,
• Sérgio H. Seabra,
• Thalya S. R. Nogueira,
• Felipe F. Moreira,
• Arícia L. E. M. Assis,
• Antônia E. A. Oliveira and
• Kátia V. S. Fernandes

Beilstein J. Nanotechnol. 2025, 16, 1197–1208, doi:10.3762/bjnano.16.88

• with smaller size, improved polydispersity index, and enhanced stability, evidenced by a higher zeta potential. FTIR analysis confirmed rotenoid incorporation into the nanocomposite and suggested hydrogen bonding or potential covalent interaction with chitosan functional groups. Bioassays demonstrated

• important parameter for assessing nanoparticle stability and biodistribution. Typically, particles acquire an electric charge at the shear plane when dispersed in a liquid, which is reflected by their zeta potential, that is key to understanding dispersion and aggregation processes in nanoformulations. Zeta

• potential values > ±30 mV are indicative of nanoparticle stability, as strong electrostatic repulsion prevents aggregation and ensures colloidal stability [20][21]. While these measurements provide important physicochemical insights, further evidence of the chemical incorporation and potential interactions

Electronic and optical properties of chloropicrin adsorbed ZnS nanotubes: first principle analysis

• Prakash Yadav,
• Boddepalli SanthiBhushan and
• Anurag Srivastava

Beilstein J. Nanotechnol. 2025, 16, 1184–1196, doi:10.3762/bjnano.16.87

• the axis of the nanotube. A density mesh cutoff of 150 Rydberg was applied to define the real-space grid for energy calculations. The ZnS NT model, consisting of 36 atoms periodically arranged along the Z-direction, was structurally optimized to achieve geometric and energetic stability. Optimization

• thermodynamic stability of the NT structure. Although these NTs are derived from flat hexagonal ZnS sheets, the resulting structures exhibit slight deviations from perfect smoothness. Specifically, a small radial anion–cation buckling of approximately ±0.1 Å was observed, consistent with previous reports on

• is added to the molecule. The calculated IP and EA values for the target molecules are summarized in Table 3. Ionization potential is critical for assessing chemical reactivity; high IP values indicate chemical inertness and greater stability, whereas low IP values suggest higher molecular reactivity

Mechanical stability of individual bacterial cells under different osmotic pressure conditions: a nanoindentation study of Pseudomonas aeruginosa

• Lizeth García-Torres,
• Idania De Alba Montero,
• Eleazar Samuel Kolosovas-Machuca,
• Facundo Ruiz,
• Sumati Bhatia,
• Jose Luis Cuellar Camacho and
• Jaime Ruiz-García

Beilstein J. Nanotechnol. 2025, 16, 1171–1183, doi:10.3762/bjnano.16.86

• stiffness remained almost unchanged when the mean values obtained from distributions for the different measuring conditions were compared. However, they differ from the mean values obtained from the middle region of bacteria. This accounts for the mechanical stability of the outer membrane of PA once a

Crystalline and amorphous structure selectivity of ignoble high-entropy alloy nanoparticles during laser ablation in organic liquids is set by pulse duration

• Robert Stuckert,
• Felix Pohl,
• Oleg Prymak,
• Ulrich Schürmann,
• Christoph Rehbock,
• Lorenz Kienle and
• Stephan Barcikowski

Beilstein J. Nanotechnol. 2025, 16, 1141–1159, doi:10.3762/bjnano.16.84

• heterogeneous catalysts or magnets. In that context, the outstanding temperature stability up to 375 °C (differential scanning calorimetry) or 500 °C (transmission electron microscopy) may motivate future application-relevant work. Keywords: amorphous; cantor alloy; compositionally complex alloy; complex solid

• occur coincidentally but are a reproducible observation (shown in Supporting Information File 1, Section S11). Thermal stability of the amorphous HEA nanoparticles Finally, we aimed to examine the temperature stability of the amorphous HEA NPs. Thereto, we conducted in situ heating experiments in TEM as

Influence of ion beam current on the structural, optical, and mechanical properties of TiO₂ coatings: ion beam-assisted vs conventional electron beam evaporation

• Agata Obstarczyk and
• Urszula Wawrzaszek

Beilstein J. Nanotechnol. 2025, 16, 1097–1112, doi:10.3762/bjnano.16.81

• structure, and the improvement of stability and homogeneity of the coatings. In addition, it is possible to modify the microstructure, resulting in dense, nearly stoichiometric films that are much more resistant to temperature and humidity changes than films deposited in the conventional EBE process [4][9

• ][10][11][12]. Electron beam evaporation is very effective for preparing transparent titanium dioxide thin films, such as optical coatings for a large variety of applications. Due to its desirable structural, optical, and electrical properties, high thermal and chemical stability, relatively low price

Fabrication of metal complex phthalocyanine and porphyrin nanoparticle aqueous colloids by pulsed laser fragmentation in liquid and their potential application to a photosensitizer for photodynamic therapy

• Taisei Himeda,
• Risako Kunitomi,
• Ryosuke Nabeya,
• Tamotsu Zako and
• Tsuyoshi Asahi

Beilstein J. Nanotechnol. 2025, 16, 1088–1096, doi:10.3762/bjnano.16.80

• any precipitation for longer than one week. The aqueous F-127 solution at 0.1 wt % concentration, which is about one tenth of the critical micelle concentration, was enough to fabricate nanoparticles with excellent dispersion stability and high production efficiency. We examined the photosensitized

• acetate [23], paclitaxel [24], naproxen and fenofibrate [25], curcumin [26], and cinnamon [27]. This work aims to fabricate aqueous colloids of MPc (M = AlCl, Fe, Co, Zn) and Pt complex octaethylporphyrin (PtOEP) (Figure 1) nanoparticles with a high dispersion stability and to demonstrate the potential

• amphiphilic polymer (Pluronic® F-127, Figure 1) [28] was used as a dispersant to ensure high dispersion stability in various aqueous environments in anticipation of future bio-applications. F-127 is a less toxic and non-ionic copolymer containing hydrophilic polyethylene oxide (PEO) and hydrophobic

Single-layer graphene oxide film grown on α-Al₂O₃(0001) for use as an adsorbent

• Shiro Entani,
• Mitsunori Honda,
• Masaru Takizawa and
• Makoto Kohda

Beilstein J. Nanotechnol. 2025, 16, 1082–1087, doi:10.3762/bjnano.16.79

• methods have been reported, including the Broadie and Hummers methods, contingent upon the oxidizing agent employed [8][14][15]. GO possesses the ultimate large surface area, low-cost production, and high chemical stability. Therefore, GO has a potential prospect to be an efficient adsorbent for metal

Piezoelectricity of hexagonal boron nitrides improves bone tissue generation as tested on osteoblasts

• Sevin Adiguzel,
• Nilay Cicek,
• Zehra Cobandede,
• Feray B. Misirlioglu,
• Hulya Yilmaz and
• Mustafa Culha

Beilstein J. Nanotechnol. 2025, 16, 1068–1081, doi:10.3762/bjnano.16.78

• hexagonal boron nitride (hBN) with ultrasound (US) stimulation is an emerging therapeutic approach. While polymers such as PVDF require electrical poling and often exhibit lower piezoelectric activity, inorganic materials inherently possess stronger piezoelectric properties and greater mechanical stability

• -dimensional (2D) material, structurally similar to graphene, consisting of alternating boron and nitrogen atoms arranged in a hexagonal lattice. It is well known for its excellent thermal stability, electrical insulation, chemical inertness, and mechanical strength. Importantly, hBN exhibits piezoelectric

• , pharmaceutical lubricants, and tissue engineering [33]. In bone tissue engineering, hBN is valued for its stability and boron-containing compounds, which support bone regeneration, especially in fracture healing [34]. For example, Atila et al. (2016) developed an hBN–hydroxyapatite (HA) composite, demonstrating

Soft materials nanoarchitectonics: liquid crystals, polymers, gels, biomaterials, and others

• Katsuhiko Ariga

Beilstein J. Nanotechnol. 2025, 16, 1025–1067, doi:10.3762/bjnano.16.77

• (Figure 6) [241]. The presence of two salts and two surfactants ensures the stability of the lyotropic liquid crystal mesophase even at elevated salt concentrations. The calcium and iron salts act as eutectic solvents, facilitating the assembly of surfactants into the lyotropic liquid crystal phase

• plastic crystals exhibits exceptional thermal stability, electrochemical stability, and ionic conductivity, making it a promising option. Yoshizawa-Fujita and co-authors investigated the impact of anion species and Mg salt concentration on the characteristics of pyrrolidinium-based organic ionic plastic

• factors that influence the electrolyte properties. The findings demonstrated that, in general, the solids displayed remarkable thermal stability and exhibited high plasticity and ionic conductivity across a broad temperature range. It has been proposed that the formation of disordered interfaces of

Multifunctional properties of bio-poly(butylene succinate) reinforced with multiwalled carbon nanotubes

• Volodymyr Krasinskyi,
• Krzysztof Bajer,
• Ludmila Dulebova,
• Nickolas Polychronopoulos,
• Oksana Krasinska and
• Daniel Kaczor

Beilstein J. Nanotechnol. 2025, 16, 1014–1024, doi:10.3762/bjnano.16.76

• strength, thermal stability, and biodegradability. However, to broaden its range of applications, certain properties require enhancement, including mechanical performance, thermal and electrical conductivity, biodegradation rate, and barrier properties [1][2][3][4][5]. The limited biodegradability of PBS

• morphology and properties of the polymer matrix by altering its structure, crystallinity, thermal stability, and mechanical behavior [9][10][11]. CNTs can be classified into two basic types, namely, single-walled carbon nanotubes (SWCNTs) and multiwalled carbon nanotubes (MWCNTs). SWCNTs exhibit slightly

• viscoelastic properties of PBS. Wang et al. [19] reported similar results when melt mixing 0.5, 1.0, 2.0, and 3.0 wt % pristine raw MWCNTs with PBS in a mixer. Additionally, they observed an increase in the thermal stability and crystallization temperature of PBS. Champa-Bujaico et al. [18] and Zeng et al. [22

A calix[4]arene-based supramolecular nanoassembly targeting cancer cells and triggering the release of nitric oxide with green light

• Cristina Parisi,
• Loredana Ferreri,
• Tassia J. Martins,
• Francesca Laneri,
• Samantha Sollima,
• Antonina Azzolina,
• Antonella Cusimano,
• Nicola D’Antona,
• Grazia M. L. Consoli and
• Salvatore Sortino

Beilstein J. Nanotechnol. 2025, 16, 1003–1013, doi:10.3762/bjnano.16.75

• with a PI of ca. 0.3 (inset Figure 4A). The supramolecular construct 1·2 was stable for days, and its formation and stability can be reasonably attributed to both hydrophobic and stacking interactions between the aliphatic chains and the aromatic regions of the host and guest components. Encapsulation

Shape, membrane morphology, and morphodynamic response of metabolically active human mitochondria revealed by scanning ion conductance microscopy

• Eric Lieberwirth,
• Anja Schaeper,
• Regina Lange,
• Ingo Barke,
• Simone Baltrusch and
• Sylvia Speller

Beilstein J. Nanotechnol. 2025, 16, 951–967, doi:10.3762/bjnano.16.73

• stability contrasts with the structural alterations reported with more violent techniques, such as deformability cytometry [37]. For mitochondria isolated using the nitrogen cavitation method, fixed mitochondria exhibit significantly smaller dimensions (Figure 4b). The reduction in size can be explained by

Tendency in tip polarity changes in non-contact atomic force microscopy imaging on a fluorite surface

• Bob Kyeyune,
• Philipp Rahe and
• Michael Reichling

Beilstein J. Nanotechnol. 2025, 16, 944–950, doi:10.3762/bjnano.16.72

• stable configuration. Unlike in the RT data, where we observe both polarity-preserving and polarity-changing tip changes, at low temperature, so far no polarity-preserving tip changes were observed. This is a plausible result as tip stability is generally considered a merit of LT measurements. However

Synthesis of biowaste-derived carbon-dot-mediated silver nanoparticles and the evaluation of electrochemical properties for supercapacitor electrodes

• Navya Kumari Tenkayala,
• Chandan Kumar Maity,
• Md Moniruzzaman and
• Subramani Devaraju

Beilstein J. Nanotechnol. 2025, 16, 933–943, doi:10.3762/bjnano.16.71

• very high, it is often followed by poor stability and an inferior specific energy density. This is due to the poor conducting nature, slow redox kinetics, as well as structural collapse which occurs throughout the redox progression [7]. EDLCs are able to provide desired stability, superior power

• water stability. The combination of EDLC-type CDs with pseudocapacitive AgNPs affords superior capacitive performance and stability, which are important for supercapacitor electrodes. The overall methodology along with the optical and electrochemical charge-storing performance have been schematically

• decent ionic mobility, TEABF4/DMSO may be helpful in maximizing the electrochemical activity. Comprehensive electrochemical experiments, such as cyclic stability, EIS, GCD, and CV evaluations, were conducted on the ASC device. A CV test (Figure 6b) of the ASC device was first performed at a fixed scan

Structural and magnetic properties of microwave-synthesized reduced graphene oxide/VO₂/Fe₂O₃ nanocomposite

• Sumanta Sahoo,
• Ankur Sood and
• Sung Soo Han

Beilstein J. Nanotechnol. 2025, 16, 921–932, doi:10.3762/bjnano.16.70

• in a honeycomb fashion enabled this special class of materials to exhibit desirable characteristics, such as enhanced electrical conductivity, higher mechanical strength, elevated surface area, and high thermal and chemical stability. Owing to such improved characteristics, graphene materials

Characterization of ion track-etched conical nanopores in thermal and PECVD SiO₂ using small angle X-ray scattering

• Shankar Dutt,
• Rudradeep Chakraborty,
• Christian Notthoff,
• Pablo Mota-Santiago,
• Christina Trautmann and
• Patrick Kluth

Beilstein J. Nanotechnol. 2025, 16, 899–909, doi:10.3762/bjnano.16.68

• dioxide [29][40][30]. Amorphous silicon dioxide (SiO2) has excellent chemical stability, well-understood surface chemistry, and compatibility with semiconductor processing, opening up new applications for track-etched nanopores in this material [30]. In this study, we report the characterization of track

Heat-induced transformation of nickel-coated polycrystalline diamond film studied in situ by XPS and NEXAFS

• Olga V. Sedelnikova,
• Yuliya V. Fedoseeva,
• Dmitriy V. Gorodetskiy,
• Yuri N. Palyanov,
• Elena V. Shlyakhova,
• Eugene A. Maksimovskiy,
• Anna A. Makarova,
• Lyubov G. Bulusheva and
• Aleksandr V. Okotrub

Beilstein J. Nanotechnol. 2025, 16, 887–898, doi:10.3762/bjnano.16.67

• diamond surfaces is initiated at 750 °C. A temperature of about 1500 °C is needed for the formation of extended graphene-like layers, and temperatures higher than 2000 °C are required for the complete conversion of the diamond (111) surface to graphitic layers [10][11]. Thermal stability of diamond

Ar⁺ implantation-induced tailoring of RF-sputtered ZnO films: structural, morphological, and optical properties

• Manu Bura,
• Divya Gupta,
• Arun Kumar and
• Sanjeev Aggarwal

Beilstein J. Nanotechnol. 2025, 16, 872–886, doi:10.3762/bjnano.16.66

• promising material for device fabrication in different fields, namely, spintronics, nanoelectronics, and photonics [1][2]. It possesses a wide bandgap of 3.37 eV [3] and has a large exciton binding energy of about 60 meV [4], which assures the stability of ZnO film-based devices such as liquid crystal