Ultrathin water layers on mannosylated gold nanoparticles

• Maiara A. Iriarte Alonso,
• Jorge H. Melillo,
• Silvina Cerveny,
• Yujin Tong and
• Alexander M. Bittner

Beilstein J. Nanotechnol. 2025, 16, 2183–2198, doi:10.3762/bjnano.16.151

• nanoparticle systems, one functionalized with an oligo(ethylene glycol) ligand, and one functionalized with a mixture of the same with a dimannoside ligand. The dimannoside ligand was chosen to mimic the surface chemistry of viral spike proteins. We characterized the particles by electron microscopy, dynamic

Missing links in nanomaterials research impacting productivity and perceptions

• Santosh K. Tiwari and
• Nannan Wang

Beilstein J. Nanotechnol. 2025, 16, 2168–2176, doi:10.3762/bjnano.16.149

• Santosh K. Tiwari Nannan Wang Centre for New Materials and Surface Engineering, Department of Chemistry, NMAM Institute of Technology (NMAMIT), Nitte (Deemed to be University), Nitte 574110, Karnataka, India State Key Laboratory of Featured Metal Materials and Life-cycle Safety for Composite

• working extensively in various aspects of nanotechnology, we find that the majority come from chemistry, physics, materials science, and metallurgy. Very few come from other fields such as mechanical, energy, electronics, biomedical engineering, and mathematics. The experts belonging to chemistry, physics

• notably less than the often-cited (and inflated) $1 trillion figure [13][14][15]. This funding has primarily supported fundamental research across materials science, chemistry, physics, and bioengineering. These efforts have led to major scientific advances, mainly in nanoelectronics, nanomedicine

Microplastic pollution in Himalayan lakes: assessment, risks, and sustainable remediation strategies

• Sameeksha Rawat,
• S. M. Tauseef and
• Madhuben Sharma

Beilstein J. Nanotechnol. 2025, 16, 2144–2167, doi:10.3762/bjnano.16.148

• development of scalable technologies for producing nanomaterials is essential for their practical application. Green chemistry methods, such as plant-based precursors or bioinspired templates, have been successfully used to synthesize nanomaterials with high photocatalytic efficiency and minimal environmental

Quality by design optimization of microemulsions for topical delivery of Passiflora setacea seed oil

• Daniel T. Pereira,
• Douglas Dourado,
• Danielle T. Freire,
• Dayanne L. Porto,
• Cícero F. S. Aragão,
• Myla L. de Souza,
• Guilherme R. S. de Araujo,
• Ana Maria Costa,
• Wógenes N. Oliveira,
• Anne Sapin-Minet,
• Éverton N. Alencar and
• Eryvaldo Sócrates T. Egito

Beilstein J. Nanotechnol. 2025, 16, 2116–2131, doi:10.3762/bjnano.16.146

• (polyethoxylated castor oil 30 mol, “PEG 30”, Oxiteno – São Paulo, SP) and sodium carboxymethyl cellulose (NaCMC – All chemistry, São Paulo, Brazil). Span® 80 was obtained from Sigma-Aldrich Inc. (St. Louis, MO – USA). Extraction of Passiflora setacea oil Oil extraction was performed using a Soxhlet apparatus with

Rapid synthesis of highly monodisperse AgSbS₂ nanocrystals: unveiling multifaceted activities in cancer therapy, antibacterial strategies, and antioxidant defense

• Funda Ulusu,
• Adem Sarilmaz,
• Yakup Ulusu,
• Faruk Ozel and
• Mahmut Kus

Beilstein J. Nanotechnol. 2025, 16, 2105–2115, doi:10.3762/bjnano.16.145

• ; antibacterial activity; antioxidant activity; cytotoxic activity; Introduction Nanoscience serves as a unique platform to reveal new properties of substances through collaborative efforts with other fields (e.g., molecular chemistry, pharmaceutical science, applied health sciences, and engineering). In recent

• ratio and enhanced surface reactivity [30]. These features, combined with the tunable surface chemistry of nanoparticles, allow for efficient interactions with free radicals and facilitate electron transfer reactions, resulting in robust antioxidant activity [49]. This activity involves scavenging free

• scavenging data, the FRAP outcome supports a dual-mechanism antioxidant model (both radical quenching and electron transfer). This suggests that the surface chemistry of AgSbS2 NCs effectively mediates both redox and radical-based pathways, making them promising candidates for applications requiring moderate

Toward clinical translation of carbon nanomaterials in anticancer drug delivery: the need for standardisation

• Michał Bartkowski,
• Francesco Calzaferri and
• Silvia Giordani

Beilstein J. Nanotechnol. 2025, 16, 2092–2104, doi:10.3762/bjnano.16.144

• nanotubes, and carbon dots, have attracted considerable interest as nanocarriers for drug delivery due to their unique physicochemical properties. Their high surface area, biocompatibility, and modifiable surface chemistry make them highly attractive for a range of biomedical applications. However, concerns

• treated. Perspective The development of a novel CNM-based drug delivery system for targeted anticancer therapeutic delivery is a complex and multistep process that involves several key milestones (Figure 3), each of which requires distinct expertise in materials science, chemistry, biology, and regulatory

• affairs. Achieving these key milestones is critical to developing a safe and effective drug delivery system that can improve the treatment of cancer. The process begins with the synthesis of CNMs tailored to specific size and surface chemistry requirements, using methods such as chemical vapour deposition

Molecular and mechanical insights into gecko seta adhesion: multiscale simulations combining molecular dynamics and the finite element method

• Yash Jain,
• Saeed Norouzi,
• Tobias Materzok,
• Stanislav N. Gorb and
• Florian Müller-Plathe

Beilstein J. Nanotechnol. 2025, 16, 2055–2076, doi:10.3762/bjnano.16.141

• microscopy (AFM) experiments. Our investigation into how gecko keratin interacts with hydrophilic and hydrophobic substrates [12] supported the importance of the water-mediating effect [10] and elucidated mechanistic differences depending on surface chemistry. A particle-based mesoscale model of a single

• , differences in adhesion originate from structure and geometry rather than interface chemistry. We analyzed the 16 spatulae individually. Figure 10, Figure 11, and Figure 12 report, respectively, their force, contact, and displacement profiles in a representative run. Across runs, orientation (pad- vs tip

Stereodiscrimination of guests in chiral organosilica aerogels studied by ESR spectroscopy

• Sebastian Polarz,
• Yasar Krysiak,
• Martin Wessig and
• Florian Kuhlmann

Beilstein J. Nanotechnol. 2025, 16, 2034–2054, doi:10.3762/bjnano.16.140

• Sebastian Polarz Yasar Krysiak Martin Wessig Florian Kuhlmann Institute of Inorganic Chemistry, Leibniz-University Hannover, Callinstrasse 9, 30167 Hannover, Germany 10.3762/bjnano.16.140 Abstract Macroporous materials containing surfaces with chiral groups are highly relevant for applications in

• chemistry; ESR spectroscopy; organic inorganic hybrids; porous materials; Introduction Chiral materials represent an evolving research field that focuses on materials whose structures lack mirror symmetry [1][2][3]. The materials exhibit chirality, and a good overview of important developments was given by

• Information File 1, Figure S3. Chiral materials A selection of different materials containing amino acids as chiral selectors was prepared (Figure 1). The advantages of using amino acids as the chiral constituent are that they are highly available from the natural pool and their coupling chemistry is highly

The cement of the tube-dwelling polychaete Sabellaria alveolata: a complex composite adhesive material

• Emilie Duthoo,
• Aurélie Lambert,
• Pierre Becker,
• Carla Pugliese,
• Jean-Marc Baele,
• Arnaud Delfairière,
• Matthew J. Harrington and
• Patrick Flammang

Beilstein J. Nanotechnol. 2025, 16, 1998–2014, doi:10.3762/bjnano.16.138

• Geology, Faculty of Engineering, University of Mons, 7000 Mons, Belgium Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, Quebec H3A 0B8, Canada 10.3762/bjnano.16.138 Abstract Adhesives produced by marine organisms offer remarkable performance and serve as a major source

Laser ablation in liquids for shape-tailored synthesis of nanomaterials: status and challenges

• Natalie Tarasenka

Beilstein J. Nanotechnol. 2025, 16, 1963–1997, doi:10.3762/bjnano.16.137

Evaluating metal-organic precursors for focused ion beam-induced deposition through solid-layer decomposition analysis

• Benedykt R. Jany,
• Katarzyna Madajska,
• Aleksandra Butrymowicz-Kubiak,
• Franciszek Krok and
• Iwona B. Szymańska

Beilstein J. Nanotechnol. 2025, 16, 1942–1951, doi:10.3762/bjnano.16.135

• Benedykt R. Jany Katarzyna Madajska Aleksandra Butrymowicz-Kubiak Franciszek Krok Iwona B. Szymanska Marian Smoluchowski Institute of Physics, Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, Lojasiewicza 11, 30348 Krakow, Poland Faculty of Chemistry, Nicolaus

PEGylated lipids in lipid nanoparticle delivery dynamics and therapeutic innovation

• Peiyang Gao

Beilstein J. Nanotechnol. 2025, 16, 1914–1930, doi:10.3762/bjnano.16.133

• chains arrange on the nanoparticle surface and the potential impacts on LNPs’ physicochemical properties by varying surface PEG density or PEG chemistry. Subsequently, PEG conformations are discussed in terms of their modulation of protein corona formation, cellular uptake, and immunogenic responses

• conjugation to cysteine residues on antibodies or peptides, enabling site-specific and stable coupling [35]. PEG lipids modified with dibenzocyclooctyne (DBCO) or azide groups can undergo strain-promoted azide-alkyne cycloaddition. This click chemistry is advantageous when conjugating sensitive targeting

• including RVG29, T7, AP2, and mApoE through thiol-maleimide click chemistry [38][39][40]. The functionalized PEG lipid was incorporated by substituting 10%, 30%, or 50% of the total 1.5 mol % PEG lipid content with DSPE-PEG-maleimide in the LNP formulation. Peptides containing a terminal cysteine residue

On the road to sustainability – application of metallic nanoparticles obtained by green synthesis in dentistry: a scoping review

• Lorena Pinheiro Vasconcelos Silva,
• Joice Catiane Soares Martins,
• Israel Luís Carvalho Diniz,
• Júlio Abreu Miranda,
• Danilo Rodrigues de Souza,
• Éverton do Nascimento Alencar,
• Moan Jéfter Fernandes Costa and
• Pedro Henrique Sette-de-Souza

Beilstein J. Nanotechnol. 2025, 16, 1851–1862, doi:10.3762/bjnano.16.128

• , merging technological advancement with ecological responsibility. Future work should prioritize clinical trials, long-term safety evaluations, and standardized protocols to fully realize their therapeutic benefits. Keywords: dentistry; green chemistry technology; metal nanoparticles; nanotechnology

• nanoparticles synthesized through green chemistry compared to those obtained via conventional methods. This enhanced activity is frequently attributed to the presence of plant-derived bioactive compounds, such as flavonoids, polyphenols, and terpenoids, that act as both reducing and capping agents [13]. These

• nanoparticles synthesized via green chemistry in dentistry. Search strategy and information sources This review was guided by the PCC framework, that is, population (P): metallic nanoparticles (e.g., silver, gold, copper, zinc oxide); concept (C): green synthesis using plant-based extracts or eco-friendly

Piezoelectricity of layered double hydroxides: perspectives regarding piezocatalysis and nanogenerators

• Evgeniy S. Seliverstov,
• Evgeniya A. Tarasenko and
• Olga E. Lebedeva

Beilstein J. Nanotechnol. 2025, 16, 1812–1817, doi:10.3762/bjnano.16.124

• Evgeniy S. Seliverstov Evgeniya A. Tarasenko Olga E. Lebedeva Department of General Chemistry, Belgorod State National Research University, Pobedy 85, 308015 Belgorod, Russian Federation 10.3762/bjnano.16.124 Abstract Recent research in alternate sources of energy such as piezoelectric energy

• the topics of piezoelectricity and layered double hydroxides in bibliographic systems and publishers such as ScienceDirect, Google Scholar, Royal Society of Chemistry, American Society of Chemistry, and MDPI. Our review is limited to articles published up to and including January 2025. Review Key

• , calibrated PFM mapping, and macroscopic tests) alongside application metrics (rate constants and degradation efficiency); (2) systematically including control experiments to isolate different contributions; (3) evaluating phase purity and interlayer chemistry, given their influence on charge mobility and

Electrical, photocatalytic, and sensory properties of graphene oxide and polyimide implanted with low- and medium-energy silver ions

• Josef Novák,
• Eva Štěpanovská,
• Petr Malinský,
• Vlastimil Mazánek,
• Jan Luxa,
• Ulrich Kentsch and
• Zdeněk Sofer

Beilstein J. Nanotechnol. 2025, 16, 1794–1811, doi:10.3762/bjnano.16.123

• Department of Inorganic Chemistry, University of Chemistry and Technology, Prague 6, 166 28, Czech Republic Ion Beam Center, Helmholtz-Zentrum Dresden Rossendorf, 01328 Dresden, Germany 10.3762/bjnano.16.123 Abstract Precise control of electrical conductivity, humidity sensitivity, and photocatalytic

Ambient pressure XPS at MAX IV

• Mattia Scardamaglia,
• Ulrike Küst,
• Alexander Klyushin,
• Rosemary Jones,
• Jan Knudsen,
• Robert Temperton,
• Andrey Shavorskiy and
• Esko Kokkonen

Beilstein J. Nanotechnol. 2025, 16, 1677–1694, doi:10.3762/bjnano.16.118

• , Lund University, Box 118, SE-221 00, Lund, Sweden 10.3762/bjnano.16.118 Abstract Ambient pressure X-ray photoelectron spectroscopy (APXPS) has emerged as an important technique for investigating surface and interface chemistry under realistic conditions, overcoming the limitations of conventional XPS

• revealed that H2 promotes the formation of a dense OH–H2O phase below the graphene. In contrast, CO alone showed minimal intercalation and instead scavenged oxygen. When CO and H2 were pulsed together, hydrogen modified the undercover chemistry: the formation of the OH-H2O phase lifts the graphene flake

• , we must ensure a well-controlled environment that is relevant to catalytic conditions. This includes enhancing the temporal resolution of APXPS measurements. Ultimately, the goal is to understand the heterogeneity of a catalytic system with greater specificity regarding site, time, chemistry, and

Nanotechnology-based approaches for the removal of microplastics from wastewater: a comprehensive review

• Nayanathara O Sanjeev,
• Manjunath Singanodi Vallabha and
• Rebekah Rubidha Lisha Rabi

Beilstein J. Nanotechnol. 2025, 16, 1607–1632, doi:10.3762/bjnano.16.114

• , and advanced membrane materials, exhibit unique properties such as high surface area, enhanced reactivity, and tunable surface chemistry, which offer promising avenues for the selective and efficient removal of MPs from water. This paper also explores the mechanism, performance and limitations of

• thermal, acidic, and saline conditions. Its self-adhesive nature, biocompatibility, and durability make it a promising preventive strategy at the source. Similarly, nanocellulose, derived from renewable biomass, exhibits a high surface area and tunable surface chemistry, making it effective for adsorbing

Dendrimer-modified carbon nanotubes for the removal and recovery of heavy metal ions from water

• Thao Quynh Ngan Tran,
• Huu Trung Nguyen,
• Subodh Kumar and
• Xuan Thang Cao

Beilstein J. Nanotechnol. 2025, 16, 1522–1532, doi:10.3762/bjnano.16.107

• Thao Quynh Ngan Tran Huu Trung Nguyen Subodh Kumar Xuan Thang Cao Faculty of Chemical Engineering, Industrial University of Ho Chi Minh City, Vietnam Department of Inorganic Chemistry, Faculty of Science, Palacký University, 17 Listopadu 12, CZ-77146 Olomouc, Czech Republic 10.3762/bjnano.16.107

• . Funding This research was funded by the Industrial University of Ho Chi Minh City. S.K. acknowledges financial support from institutional sources of the Department of Inorganic Chemistry, Palacký University Olomouc, Czech Republic. Conflict of Interest The authors confirm that there is no conflict of

Cross-reactivities in conjugation reactions involving iron oxide nanoparticles

• Shoronia N. Cross,
• Katalin V. Korpany,
• Hanine Zakaria and
• Amy Szuchmacher Blum

Beilstein J. Nanotechnol. 2025, 16, 1504–1521, doi:10.3762/bjnano.16.106

• Shoronia N. Cross Katalin V. Korpany Hanine Zakaria Amy Szuchmacher Blum Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, QC H3A 0B8, Canada 10.3762/bjnano.16.106 Abstract The preparation of multimodal nanoparticles by capping magnetic iron oxide nanoparticles

• (IONPs) with functional organic molecules is a major area of research for biomedical applications. Conjugation reactions, such as carbodiimide coupling and the highly selective class of reactions known as “click chemistry”, have been instrumental in tailoring the ligand layers of IONPs to produce

• erroneous conclusions about the efficacy of conjugation reactions, which can have detrimental impacts on the functionality and safety of IONPs in biomedical applications. Keywords: click chemistry; copper-catalyzed azide–alkyne cycloaddition; disulfide reduction; iron oxide nanoparticles; thiol–maleimide

Nanomaterials for biomedical applications

• Iqra Zainab,
• Zohra Naseem,
• Syeda Rubab Batool,
• Filippo Pierini,
• Seda Kizilel and
• Muhammad Anwaar Nazeer

Beilstein J. Nanotechnol. 2025, 16, 1499–1503, doi:10.3762/bjnano.16.105

• . Nanomaterials have gained popularity in medicine because they can be altered according to the need [1]. Researchers can tailor the shape, surface chemistry, and other specific properties of materials to deliver desirable traits. In particular, some nanoparticles can be used to deliver drugs to a tumor, reducing

• that nanomaterials have many uses in medicine, from targeted drug delivery to improved imaging, promoting tissue regeneration, and enhancing the functions of implants and prosthetic devices. Their adaptability makes them so powerful as scientists can change the structure, chemistry, or properties of a

Laser processing in liquids: insights into nanocolloid generation and thin film integration for energy, photonic, and sensing applications

• Akshana Parameswaran Sreekala,
• Pooja Raveendran Nair,
• Jithin Kundalam Kadavath,
• Bindu Krishnan,
• David Avellaneda Avellaneda,
• M. R. Anantharaman and
• Sadasivan Shaji

Beilstein J. Nanotechnol. 2025, 16, 1428–1498, doi:10.3762/bjnano.16.104

The role of biochar in combating microplastic pollution: a bibliometric analysis in environmental contexts

• Tuan Minh Truong Dang,
• Thao Thu Thi Huynh,
• Guo-Ping Chang-Chien and
• Ha Manh Bui

Beilstein J. Nanotechnol. 2025, 16, 1401–1416, doi:10.3762/bjnano.16.102

• , and disrupt microbial diversity and nutrient cycling. Biochar, a stable and eco-friendly material, has demonstrated effectiveness in mitigating these effects by restoring soil chemistry, enhancing microbial diversity and improving crop productivity. Recent studies report that biochar increases crop

• interactions in soil [31]. Biochar properties The physical and chemical properties of biochar depend significantly on the composition of its feedstock [46]. Molecular model calculations and quantum chemistry analyses suggest that biochar derived from wood exhibits superior physical properties, such as porosity

Enhancing the therapeutical potential of metalloantibiotics using nano-based delivery systems

• Alejandro Llamedo,
• Marina Cano,
• Raquel G. Soengas and
• Francisco J. García-Alonso

Beilstein J. Nanotechnol. 2025, 16, 1350–1366, doi:10.3762/bjnano.16.98

• ]. Dendrimers, with their hyperbranched structures, can be precisely controlled for size, shape, and surface chemistry, allowing for highly targeted delivery of anti-biofilms drugs or nucleic acids [81][82]. Polymeric NPs offer several advantages, including biodegradability, biocompatibility, and stability

• metalloantibiotics and advanced drug delivery technologies opens new avenues for combating drug-resistant infections. In this regard, a multidisciplinary approach, bridging chemistry, nanotechnology, microbiology, and pharmacology will be pivotal in advancing this emerging field toward clinical application. The role

Enhancing the photoelectrochemical performance of BiOI-derived BiVO₄ films by controlled-intensity current electrodeposition

• Huu Phuc Dang,
• Khanh Quang Nguyen,
• Nguyen Thi Mai Tho and
• Tran Le

Beilstein J. Nanotechnol. 2025, 16, 1289–1301, doi:10.3762/bjnano.16.94

• . Larger grains typically result in fewer grain boundaries, reducing phonon scattering and enhancing vibrational coherence. Raman spectra also provide insights into the influence of fabrication conditions on surface chemistry. The relative intensities of the peaks suggest that higher deposition currents

Mechanical stability of individual bacterial cells under different osmotic pressure conditions: a nanoindentation study of Pseudomonas aeruginosa

• Lizeth García-Torres,
• Idania De Alba Montero,
• Eleazar Samuel Kolosovas-Machuca,
• Facundo Ruiz,
• Sumati Bhatia,
• Jose Luis Cuellar Camacho and
• Jaime Ruiz-García

Beilstein J. Nanotechnol. 2025, 16, 1171–1183, doi:10.3762/bjnano.16.86

• Luis potosí, SLP, México Facultad de Ciencias, Universidad Autónoma de San Luis Potosí, Parque Chapultepec 1570, Privadas del Pedregal 78295, San Luis Potosí, S.L.P. México Department of Chemistry, Faculty of Science and Engineering, Swansea University, Singleton Campus, Swansea SA2 8PP, United Kingdom

• the Deutsche Forschungsgemeinschaft (DFG) – Project ID: 458564133, and the Royal Society of Chemistry (RSC) RG\R1\241050. The corresponding author would like to thank the National postdoctoral Fellowship program SECIHTI (CONACYT) Mexico, for the financial support.