Rapid controlled synthesis of gold–platinum nanorods with excellent photothermal properties under 808 nm excitation

• Jialin Wang,
• Qianqian Duan,
• Min Yang,
• Boye Zhang,
• Li Guo,
• Pengcui Li,
• Wendong Zhang and
• Shengbo Sang

Beilstein J. Nanotechnol. 2021, 12, 462–472, doi:10.3762/bjnano.12.37

• of Technology, Taiyuan 030024, Shanxi, China Department of Orthopedics, the Second Hospital of Shanxi Medical University, Taiyuan 030024, Shanxi, China 10.3762/bjnano.12.37 Abstract Noble metal nanomaterials are particularly suitable as photothermal transduction agents (PTAs) with high photothermal

A review on nanostructured silver as a basic ingredient in medicine: physicochemical parameters and characterization

• Gabriel M. Misirli,
• Kishore Sridharan and
• Shirley M. P. Abrantes

Beilstein J. Nanotechnol. 2021, 12, 440–461, doi:10.3762/bjnano.12.36

• in the manufacture of medical devices to prevent adhesion, colonization, and formation of microbial biofilms on the surfaces of these devices. Moreover, the history of AgNPs as a broad spectrum microbicidal agent places it as a viable candidate to be one of the basic ingredients of antibiotics to be

Intracranial recording in patients with aphasia using nanomaterial-based flexible electronics: promises and challenges

• Qingchun Wang and
• Wai Ting Siok

Beilstein J. Nanotechnol. 2021, 12, 330–342, doi:10.3762/bjnano.12.27

• -noise ratio (Figure 5c, right). The real-time signals of cortical activities in different medical and drug-induced epileptic states were precisely measured when the iWEBS array was used in freely moving mice. Combined with optogenetic mapping techniques, long-range cortical interactions were

Doxorubicin-loaded gold nanorods: a multifunctional chemo-photothermal nanoplatform for cancer management

• Uzma Azeem Awan,
• Abida Raza,
• Shaukat Ali,
• Rida Fatima Saeed and
• Nosheen Akhtar

Beilstein J. Nanotechnol. 2021, 12, 295–303, doi:10.3762/bjnano.12.24

• Uzma Azeem Awan Abida Raza Shaukat Ali Rida Fatima Saeed Nosheen Akhtar Department of Biological Sciences, National University of Medical Sciences (NUMS), Rawalpindi, Pakistan NILOP Nanomedicine Research Laboratories, National Institute of Lasers and Optronics College, (PIEAS), Islamabad, Pakistan

• Medical Toxicology Lab, Department of Zoology, Government College University Lahore, Lahore-54000, Pakistan 10.3762/bjnano.12.24 Abstract Two of the limitations associated with cancer treatment are the low efficacy and the high dose-related side effects of anticancer drugs. The purpose of the current

• based on chemotherapy and photothermal strategies appears to be a promising platform in cancer management. Keywords: chemotherapy; doxorubicin; gold nanorods; NIR laser; photothermal therapy; Introduction Despite the enormous advances in medical research, cancer is still the second most common cause

Characterization, bio-uptake and toxicity of polymer-coated silver nanoparticles and their interaction with human peripheral blood mononuclear cells

• Sahar Pourhoseini,
• Reilly T. Enos,
• Angela E. Murphy,
• Bo Cai and
• Jamie R. Lead

Beilstein J. Nanotechnol. 2021, 12, 282–294, doi:10.3762/bjnano.12.23

• , Columbia, SC, 29208, United States 10.3762/bjnano.12.23 Abstract Silver nanoparticles (AgNPs) are widely used in medical applications due to their antibacterial and antiviral properties. Despite the extensive study of AgNPs, their toxicity and their effect on human health is poorly understood, as a result

• . Discussion Because of the antibacterial properties of AgNPs and their use in medical applications, there have been several studies on their effects on human blood cells [26][27][28]. Most of the previous studies investigating uptake and toxicity of AgNPs in human PBMCs have failed to report procurement

Differences in surface chemistry of iron oxide nanoparticles result in different routes of internalization

• Barbora Svitkova,
• Vlasta Zavisova,
• Veronika Nemethova,
• Martina Koneracka,
• Miroslava Kretova,
• Filip Razga,
• Monika Ursinyova and
• Alena Gabelova

Beilstein J. Nanotechnol. 2021, 12, 270–281, doi:10.3762/bjnano.12.22

• Physics, Slovak Academy of Sciences, Watsonova 47, 040 01 Kosice, Slovakia Faculty of Medicine, Comenius University, Spitalska 24, 813 72 Bratislava, Slovakia Selecta Biotech SE, Istrijska 20, 841 07 Bratislava, Slovakia Slovak Medical University, Limbova 12, 833 03 Bratislava, Slovakia 10.3762/bjnano

• . Plasmid CLLCb-pEGFP was kindly provided by Prof. Ernst J. Ungewickell (Department of Cell Biology, Centre of Anatomy, Hannover Medical School, Germany) and vector pcDNA 3.1 (+) was kindly provided by Katarina Luciakova, DSc. (Cancer Research Institute, Biomedical Research Center SAS, Bratislava, Slovakia

The nanomorphology of cell surfaces of adhered osteoblasts

• Christian Voelkner,
• Mirco Wendt,
• Regina Lange,
• Max Ulbrich,
• Martina Gruening,
• Susanne Staehlke,
• Barbara Nebe,
• Ingo Barke and
• Sylvia Speller

Beilstein J. Nanotechnol. 2021, 12, 242–256, doi:10.3762/bjnano.12.20

• Rostock, Albert-Einstein-Str. 23, 18059 Rostock, Germany Department of Cell Biology, Rostock University Medical Center, Schillingallee 69, 18057 Rostock, Germany 10.3762/bjnano.12.20 Abstract The functionality of living cells is inherently linked to subunits with dimensions ranging from several

Toward graphene textiles in wearable eye tracking systems for human–machine interaction

• Ata Jedari Golparvar and
• Murat Kaya Yapici

Beilstein J. Nanotechnol. 2021, 12, 180–189, doi:10.3762/bjnano.12.14

• interaction (HCI/HMI), and personal medical devices; provided that, seamless sensing of eye activity and processing thereof is achieved by a truly wearable, low-cost, and accessible technology. The present study demonstrates an alternative to the bulky and expensive camera-based eye tracking systems and

Imaging of SARS-CoV-2 infected Vero E6 cells by helium ion microscopy

• Natalie Frese,
• Patrick Schmerer,
• Martin Wortmann,
• Matthias Schürmann,
• Matthias König,
• Michael Westphal,
• Friedemann Weber,
• Holger Sudhoff and
• Armin Gölzhäuser

Beilstein J. Nanotechnol. 2021, 12, 172–179, doi:10.3762/bjnano.12.13

• Veterinary Medicine, Justus-Liebig-University Giessen, Germany Faculty of Engineering and Mathematics, Bielefeld University of Applied Sciences, Bielefeld, Germany University Clinic for Otolaryngology, Head and Neck Surgery, Medical Faculty OWL at Bielefeld University, Germany 10.3762/bjnano.12.13 Abstract

Paper-based triboelectric nanogenerators and their applications: a review

• Jing Han,
• Nuo Xu,
• Yuchen Liang,
• Mei Ding,
• Junyi Zhai,
• Qijun Sun and
• Zhong Lin Wang

Beilstein J. Nanotechnol. 2021, 12, 151–171, doi:10.3762/bjnano.12.12

• on Nanoenergy Research, School of Physical Science and Technology, Guangxi University, Nanning, 530004, P. R. China Qichen (Shanghai) Medical Co., Ltd., Shanghai 201319, P. R. China College of Materials Science and Engineering, Changsha University of Science & Technology, Changsha, 410114, P. R

A review on the green and sustainable synthesis of silver nanoparticles and one-dimensional silver nanostructures

• Sina Kaabipour and
• Shohreh Hemmati

Beilstein J. Nanotechnol. 2021, 12, 102–136, doi:10.3762/bjnano.12.9

• used in utensils for eating and drinking, most probably due to the antimicrobial activities of silver which were discovered from experience during ancient centuries [45]. Later on, there were further instances where silver was used for medical purposes. For instance, Avi-Cenna applied silver filings

• unique surface characteristics [228]. Therefore, for safe biological applications (i.e. in the medical and food industry), this approach would be preferred as an alternative for methods that necessarily require the use of chemical stabilizers [108][112]. In addition, the small NP size, low agglomeration

The role of gold atom concentration in the formation of Cu–Au nanoparticles from the gas phase

• Yuri Ya. Gafner,
• Svetlana L. Gafner,
• Darya A. Ryzkova and
• Andrey V. Nomoev

Beilstein J. Nanotechnol. 2021, 12, 72–81, doi:10.3762/bjnano.12.6

• catalysis of industrial reactions, optics, optoelectronics, and medical applications. We also noted that predicting the structure of nanoparticles consisting of different chemical elements is not a trivial task because of its dependence on both the size and the complex energy landscape. To achieve

Effect of different silica coatings on the toxicity of upconversion nanoparticles on RAW 264.7 macrophage cells

• Cynthia Kembuan,
• Helena Oliveira and
• Christina Graf

Beilstein J. Nanotechnol. 2021, 12, 35–48, doi:10.3762/bjnano.12.3

• chemical inertness and relatively low toxicity are also claimed advantages [7][10][11]. Due to these unique features, UCNPs have already been used in medical and biological applications, such as multimodal bioimaging, drug delivery, photodynamic therapy, and biosensing [9][12][13][14][15][16][17]. However

Bio-imaging with the helium-ion microscope: A review

• Matthias Schmidt,
• James M. Byrne and
• Ilari J. Maasilta

Beilstein J. Nanotechnol. 2021, 12, 1–23, doi:10.3762/bjnano.12.1

• samples, rendering HIM a promising high-resolution imaging technique for biological samples. Starting with studies focused on medical research, the last decade has seen some particularly spectacular high-resolution images in studies focused on plants, microbiology, virology, and geomicrobiology. However

• materials science, HIM is much less frequently used for imaging biological specimens. To date, 13 years after the first HIMs were commissioned, only about 70 papers (we are aware of 72) have been published which include HIM bio-imaging data for medical, geomicrobiological, or life sciences. Figure 1

• recent developments reported for bio-imaging using HIM for biological, medical, plant, animal, microbiology, virology, and geomicrobiology studies. We briefly discuss the imaging, detection, and analytical technologies which make the HIM so powerful and explain why these technologies have been so

Free and partially encapsulated manganese ferrite nanoparticles in multiwall carbon nanotubes

• Saja Al-Khabouri,
• Salim Al-Harthi,
• Toru Maekawa,
• Mohamed E. Elzain,
• Ashraf Al-Hinai,
• Ahmed D. Al-Rawas,
• Abbsher M. Gismelseed,
• Ali A. Yousif and
• Myo Tay Zar Myint

Beilstein J. Nanotechnol. 2020, 11, 1891–1904, doi:10.3762/bjnano.11.170

• materials have the potential to be used for the transport of drugs to specific locations in the body as well as in medical diagnosis without the need for surgical interference [6]. Pal et al. synthesized Fe3O4 encapsulated in carbon nanostraws and reported an enhancement in the magnetic properties, which

Electron beam-induced deposition of platinum from Pt(CO)₂Cl₂ and Pt(CO)₂Br₂

• Aya Mahgoub,
• Hang Lu,
• Rachel M. Thorman,
• Konstantin Preradovic,
• Titel Jurca,
• Lisa McElwee-White,
• Howard Fairbrother and
• Cornelis W. Hagen

Beilstein J. Nanotechnol. 2020, 11, 1789–1800, doi:10.3762/bjnano.11.161

• . Acknowledgements We would like to thank the University Medical Center Groningen for helping and allowing us to use their equipment to do EDX measurements. AM and CWH gratefully acknowledge discussions with Jan H. Bredehöft and Petra Swiderek from the University of Bremen, Germany. Funding The work presented here

Cardiomyocyte uptake mechanism of a hydroxyapatite nanoparticle mediated gene delivery system

• Hiroaki Komuro,
• Masahiro Yamazoe,
• Kosuke Nozaki,
• Akiko Nagai and
• Tetsuo Sasano

Beilstein J. Nanotechnol. 2020, 11, 1685–1692, doi:10.3762/bjnano.11.150

• Hiroaki Komuro Masahiro Yamazoe Kosuke Nozaki Akiko Nagai Tetsuo Sasano Department of Cardiovascular Physiology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Bunkyo, Tokyo 113-8510, Japan Department of Cardiovascular Medicine, Graduate School of Medical and

• Dental Sciences, Tokyo Medical and Dental University, Bunkyo, Tokyo 113-8510, Japan Department of Bio-informational Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, Bunkyo, Tokyo 113-8510, Japan Department of Restorative Sciences, Graduate School of Medical and Dental

• Sciences, Tokyo Medical and Dental University, Bunkyo, Tokyo 113-8510, Japan Department of Anatomy, School of Dentistry, Aichi Gakuin University, Chikusa, Nagoya 464-8650, Japan 10.3762/bjnano.11.150 Abstract Gene therapy has been explored as a future alternative for treating heart disease. Among several

Piezoelectric sensor based on graphene-doped PVDF nanofibers for sign language translation

• Shuai Yang,
• Xiaojing Cui,
• Rui Guo,
• Zhiyi Zhang,
• Shengbo Sang and
• Hulin Zhang

Beilstein J. Nanotechnol. 2020, 11, 1655–1662, doi:10.3762/bjnano.11.148

• system can be used for other applications, such as tactile perception, medical rehabilitation, and gesture games (Figure 4d). Conclusion A self-powered PES based on GR-doped PVDF has been fabricated. Its sensitivity to pressure and bending was examined, especially regarding the reliable measurment of the

• systems based on piezoelectric sensors, which are of great value in fields such as human–machine interaction, medical rehabilitation, and virtual reality. Experimental Chemicals: PVDF (Mw = 2.75 × 105 g/mol) powder was purchased from SOLEF (USA). N,N-Dimethylformamide (DMF) was provided by China National

Selective detection of complex gas mixtures using point contacts: concept, method and tools

• Alexander P. Pospelov,
• Victor I. Belan,
• Dmytro O. Harbuz,
• Volodymyr L. Vakula,
• Lyudmila V. Kamarchuk,
• Yuliya V. Volkova and
• Gennadii V. Kamarchuk

Beilstein J. Nanotechnol. 2020, 11, 1631–1643, doi:10.3762/bjnano.11.146

• ]. The main goal of these studies is to find peculiarities of the human metabolism that are typical of various diseases and to develop new noninvasive medical diagnostic methods. The functioning of the human body is accompanied by the biosynthesis of specific chemical substances. These substances become

• part of the exhaled breath and, as such, can be used as markers for breath characterization. Hence, it is important to detect single components of the exhaled breath for medical purposes. Mass spectrometry, gas chromatography–mass spectrometry, as well as various optical spectroscopy techniques are

• successfully used to detect substances in the breath [14][15][16][17][18][19][20]. Yet, the high costs of the equipment and the need for highly skilled staff to operate and maintain it impede the large-scale implementation of these techniques in daily medical practice. From this point of view, it seems

Electrokinetic characterization of synthetic protein nanoparticles

• Daniel F. Quevedo,
• Cody J. Lentz,
• Adriana Coll de Peña,
• Yazmin Hernandez,
• Nahal Habibi,
• Rikako Miki,
• Joerg Lahann and
• Blanca H. Lapizco-Encinas

Beilstein J. Nanotechnol. 2020, 11, 1556–1567, doi:10.3762/bjnano.11.138

• ; bicompartmental particles; dielectrophoresis; electrokinetics; electrophoresis; electro-osmosis; microfluidics; protein nanoparticles; Introduction Over the past 30 years, nanoparticles have been developed for a wide variety of scientific applications, ranging from medical imaging to drug delivery and enzyme

Optically and electrically driven nanoantennas

• Monika Fleischer,
• Dai Zhang and
• Alfred J. Meixner

Beilstein J. Nanotechnol. 2020, 11, 1542–1545, doi:10.3762/bjnano.11.136

• low-background medical imaging or nanolasers [33]. Electrically driven optical antennas emit light when a bias voltage is applied to the contacted antenna arms that are forming a tunnel junction. Inelastic electron tunneling through the gap excites gap–plasmon oscillations leading to the emission of

Antimicrobial metal-based nanoparticles: a review on their synthesis, types and antimicrobial action

• Matías Guerrero Correa,
• Fernanda B. Martínez,
• Cristian Patiño Vidal,
• Camilo Streitt,
• Juan Escrig and
• Carol Lopez de Dicastillo

Beilstein J. Nanotechnol. 2020, 11, 1450–1469, doi:10.3762/bjnano.11.129

• medical field the microbial agents are important for reducing the risk of contamination in invasive and routine interventions, and in the textile industry, they can limit the growth of microorganisms due to sweat. The combination of nanotechnology with materials that have an intrinsic antimicrobial

• been applied in the food packaging industry and also in the medical field, as shown in Table 3. ZnO is a semiconductor metal oxide with significant antimicrobial properties that can be further improved when applied as a nanomaterial. ZnO NPs have potential application in food preservation as well as

• their excellent properties, CuO NPs have attracted great interest from the healthcare, food packaging, medical, and environmental industries [120][134]. This metal oxide is capable of disrupting the normal function of the cell membrane, changing its permeability and the cellular respiration process [135

Transient coating of γ-Fe₂O₃ nanoparticles with glutamate for its delivery to and removal from brain nerve terminals

• Konstantin Paliienko,
• Artem Pastukhov,
• Michal Babič,
• Daniel Horák,
• Olga Vasylchenko and
• Tatiana Borisova

Beilstein J. Nanotechnol. 2020, 11, 1381–1393, doi:10.3762/bjnano.11.122

• nanoparticle surface before medical application. Autologous biocorona formation is considered to be very promising for advanced nanovesicle technology for cancer treatment [13][37]. Effective magnetic field-mediated glutamate delivery using γ-Fe2O3 nanoparticles can be used for the modulation of extracellular

• -2020) and “Smart sensory devices of a new generation based on modern materials and technologies for 2018–2022” (#18/1-2020) and the Czech Science Foundation (No. 20-02177J). The study was supported also by the Cedars-Sinai Medical Center (CSMC) - Research Association for Regional Cooperation in the

Magnetohydrodynamic stagnation point on a Casson nanofluid flow over a radially stretching sheet

• Ganji Narender,
• Kamatam Govardhan and
• Gobburu Sreedhar Sarma

Beilstein J. Nanotechnol. 2020, 11, 1303–1315, doi:10.3762/bjnano.11.114

• and medical science in the last decades Since heat energy provides society with several benefits, the field of thermodynamics is applicable to and effectively connected with other fields. Heat transport processes plays a fundamental role in building design [1], fuel-filling systems [2], air compressor

• Brownian motion and thermophoretic properties. Due to these features, nanoparticles are widely used in catalysis, imaging, energy-based research, microelectronics, and in other applications in the medical and environmental fields. These nanoparticles are composed of metals and nonmetals and are frequently

Influence of the magnetic nanoparticle coating on the magnetic relaxation time

• Mihaela Osaci and
• Matteo Cacciola

Beilstein J. Nanotechnol. 2020, 11, 1207–1216, doi:10.3762/bjnano.11.105

• absence of an external magnetic field [11][12]. This can be a potential problem when ferrofluids are used in medical applications, since nanoparticle agglomeration and sedimentation can create thrombi inside the blood vessels [13]. Controlling nanoparticle agglomeration is essential to improve the