Potential of a deep eutectic solvent in silver nanoparticle fabrication for antibiotic residue detection

• Le Hong Tho,
• Bui Xuan Khuyen,
• Ngoc Xuan Dat Mai and
• Nhu Hoa Thi Tran

Beilstein J. Nanotechnol. 2024, 15, 426–434, doi:10.3762/bjnano.15.38

• stirring, the obtained Ag NPs-DES were washed with DI water several times, and the pellets were re-dispersed in DI water for further use. The Ag NPs-DES thin film was prepared following the procedure for self-assembly monolayer construction. A clean glass substrate was treated with oxygen plasma to form

Classification and application of metal-based nanoantioxidants in medicine and healthcare

• Nguyen Nhat Nam,
• Nguyen Khoi Song Tran,
• Tan Tai Nguyen,
• Nguyen Ngoc Trai,
• Nguyen Phuong Thuy,
• Hoang Dang Khoa Do,
• Nhu Hoa Thi Tran and
• Kieu The Loan Trinh

Beilstein J. Nanotechnol. 2024, 15, 396–415, doi:10.3762/bjnano.15.36

• antioxidant appearing in low-density lipoprotein and human blood plasma contributing to the decrease of oxidative stress. Its mechanism of action relies on the ability to transfer the phenolic H atom to a peroxyl radical (ROO•) much more rapidly than the propagation reactions [50][51][52][53]. Despite the

• to biological systems can cause detrimental effects on human health. Sobolewski et al. confirmed the Fe2O3 nanoparticles with sizes between 11.2 and 13.6 nm can lead to oxidative damage and neurotoxicity in the mouse brain [189]. Meanwhile, the rapid clearance of SiNPs from blood depletes plasma

Modulated critical currents of spin-transfer torque-induced resistance changes in NiCu/Cu multilayered nanowires

• Mengqi Fu,
• Roman Hartmann,
• Julian Braun,
• Sergej Andreev,
• Torsten Pietsch and
• Elke Scheer

Beilstein J. Nanotechnol. 2024, 15, 360–366, doi:10.3762/bjnano.15.32

• the surface area of the AAO template (or Si substrate) is isolated from the bottom electrodes and the magnetic nanowires, thereby largely improving the flexibility for the design of the top electrodes. After removing the overgrowth by a thin blade or milling in argon plasma, a thick Al film of 180 nm

Nanomedicines against Chagas disease: a critical review

• Maria Jose Morilla,
• Kajal Ghosal and
• Eder Lilia Romero

Beilstein J. Nanotechnol. 2024, 15, 333–349, doi:10.3762/bjnano.15.30

• ]. The dosage of BNZ has been reported to be inadequate [21]. In children, markedly lower plasma BNZ concentrations than those previously reported in adults treated with comparable BNZ milligram per kilogram doses (possibly due to a higher clearance/bioavailability), but still retaining a high

• simulations showed that reducing the cumulative dose from 2.5 mg/kg/12 h to 2.5 mg/kg/24 h rendered BNZ plasma concentrations within the accepted therapeutic range of 3 to 6 mg/L [22]. This is an important point: When BNZ toxicity is attributed to overdosing, it could be simply reduced by reducing its dose

• . The implementation of shorter treatments has also been proposed [23][24]. Other reports suggest, nonetheless, that the overdosage of BNZ as the origin of ADRs is debatable. Studies implemented with adult patients not only failed to connect the manifestation of ADRs with the BNZ plasma levels but also

Comparative electron microscopy particle sizing of TiO₂ pigments: sample preparation and measurement

• Ralf Theissmann,
• Christopher Drury,
• Markus Rohe,
• Thomas Koch,
• Jochen Winkler and
• Petr Pikal

Beilstein J. Nanotechnol. 2024, 15, 317–332, doi:10.3762/bjnano.15.29

• log-normal assumption. The probability p that the particle size distribution is not log-normal is given in Table 2 together with the results of the fits. Indirect particle size measurements and optical properties Single-particle inductively coupled plasma mass spectrometry (spICP-MS) measurements are

Ultrasensitive and ultrastretchable metal crack strain sensor based on helical polydimethylsiloxane

• Shangbi Chen,
• Dewen Liu,
• Weiwei Chen,
• Huajiang Chen,
• Jiawei Li and
• Jinfang Wang

Beilstein J. Nanotechnol. 2024, 15, 270–278, doi:10.3762/bjnano.15.25

• structured PDMS was initially cleansed through a 5 min Ar plasma sputtering and, subsequently, coated with a 10 nm thick Ti adhesion layer. After that, ion beam sputtering was utilized to deposit a 50 nm thick Au thin film onto the outer surface of the helically shaped PDMS. Then, a controlled pre-stretch

Ion beam processing of DNA origami nanostructures

• Leo Sala,
• Agnes Zerolová,
• Violaine Vizcaino,
• Alain Mery,
• Alicja Domaracka,
• Hermann Rothard,
• Philippe Boduch,
• Dominik Pinkas and
• Jaroslav Kocišek

Beilstein J. Nanotechnol. 2024, 15, 207–214, doi:10.3762/bjnano.15.20

• . Preparation of dry samples and AFM imaging Silicon wafers were cut into ∼7 × 7 mm2 chips and were then plasma-cleaned in air using a Roplass RPS40+ plasma cleaner, which generates a thin layer of plasma by diffuse coplanar surface barrier discharge [35]. The Si surface is exposed to the thin plasma layer for

• the generation of plasma from air affecting the nanostructures and DNA–substrate interactions. Despite the underlying mechanism, which is worth of further exploration, this behavior should be emphasized in the present content. Random irradiation of the origami-deposited nanostructures results in a

Graphene removal by water-assisted focused electron-beam-induced etching – unveiling the dose and dwell time impact on the etch profile and topographical changes in SiO₂ substrates

• Aleksandra Szkudlarek,
• Jan M. Michalik,
• Inés Serrano-Esparza,
• Zdeněk Nováček,
• Veronika Novotná,
• Piotr Ozga,
• Czesław Kapusta and
• José María De Teresa

Beilstein J. Nanotechnol. 2024, 15, 190–198, doi:10.3762/bjnano.15.18

• induced in the SiO2 upper layer were cleaned for ten minutes in an ultrasonic bath with acetone, isopropanol, and O2 plasma before being placed in the microscope chamber. Graphene and SiO2/Si etching The samples were placed inside the SEM-Versa 3D (FEI), which also operates at LV mode. The chamber was

Nanocarrier systems loaded with IR780, iron oxide nanoparticles and chlorambucil for cancer theragnostics

• Phuong-Thao Dang-Luong,
• Hong-Phuc Nguyen,
• Loc Le-Tuan,
• Xuan-Thang Cao,
• Vy Tran-Anh and
• Hieu Vu Quang

Beilstein J. Nanotechnol. 2024, 15, 180–189, doi:10.3762/bjnano.15.17

• -life. When NPs are administered, they come into contact with blood cells and plasma proteins, which may cause adsorption or opsonization by serum proteins [35]. However, these proteins will have a reduced probability of interacting with our negatively charged nanoparticles, as most proteins are

Curcumin-loaded nanostructured systems for treatment of leishmaniasis: a review

• Douglas Dourado,
• Thayse Silva Medeiros,
• Éverton do Nascimento Alencar,
• Edijane Matos Sales and
• Fábio Rocha Formiga

Beilstein J. Nanotechnol. 2024, 15, 37–50, doi:10.3762/bjnano.15.4

• leishmaniasis. Additionally, this molecule produces reactive oxygen species (ROS) and elevates cytosolic calcium. These occur in the exposure of phosphatidylserine to the outer plasma membrane leaflet and DNA fragmentation, causing the death of the leishmaniasis parasite [47][52]. Despite its promising

Nanotechnological approaches in the treatment of schistosomiasis: an overview

• Lucas Carvalho,
• Michelle Sarcinelli and
• Beatriz Patrício

Beilstein J. Nanotechnol. 2024, 15, 13–25, doi:10.3762/bjnano.15.2

• encapsulating PZQ. They observed that the drug took more than one week in vitro to be released. A pharmacokinetic study in vivo also showed that the PZQ concentration in the plasma was sustained for longer times when the nanoformulation was studied in mice. Thus, the results show that solid lipid nanoparticles

TEM sample preparation of lithographically patterned permalloy nanostructures on silicon nitride membranes

• Joshua Williams,
• Michael I. Faley,
• Joseph Vimal Vas,
• Peng-Han Lu and
• Rafal E. Dunin-Borkowski

Beilstein J. Nanotechnol. 2024, 15, 1–12, doi:10.3762/bjnano.15.1

• or volatile particles, which can be pumped out. RIE of nickel–iron alloys has been carried out using inductively coupled plasma RIE with argon and chlorine [34] or with NH3 and CO [35]. Stencil lithography requires further optimization although possible applications are attractive because of the

• of different sizes. Ion beam etching process. Comparison between normal patterned resist (top) and reflowed resist (bottom). From left to right: patterned resist, nanodisk after IBE, and nanodisk after plasma cleaning. (a) SEM image of a Py disk (1 µm diameter, 80 nm thickness) at a tilt angle. (b

Hierarchically patterned polyurethane microgrooves featuring nanopillars or nanoholes for neurite elongation and alignment

• Lester Uy Vinzons,
• Guo-Chung Dong and
• Shu-Ping Lin

Beilstein J. Nanotechnol. 2023, 14, 1157–1168, doi:10.3762/bjnano.14.96

• hydrophilic, O2 plasma-treated substrates [21]. We measured the water contact angle (CA) on the PU samples (Figure 1I) and found that all of the as-fabricated samples were hydrophobic (CA > 90°), with the nanostructured substrates being more so. Since the CA for flat PU indicates a hydrophobic surface, the

• increase in CA on the nanopillar and nanohole substrates may be due to either a Wenzel- or a Cassie-type of wetting [22]. To improve wetting on the substrates, we treated our samples with mild O2 plasma before laminin incubation. After plasma treatment, all samples became hydrophilic (CA < 80°), with the

• nanopillar substrate having the smallest CAs (CA ≈ 30°). Based on confocal fluorescence microscopy of immunostained samples (Figure 1J–L), laminin successfully adsorbed onto the O2 plasma-treated PU samples. There was good laminin coverage on all of the samples, even on the nanostructures, as indicated by

Elasticity, an often-overseen parameter in the development of nanoscale drug delivery systems

• Agnes-Valencia Weiss and
• Marc Schneider

Beilstein J. Nanotechnol. 2023, 14, 1149–1156, doi:10.3762/bjnano.14.95

• measured. The results show that the plasma insulin levels where higher for harder NPs, and this correlated with blood glucose reduction. Furthermore, 3 h after application, they found a larger amount of hard NPs in the intestinal villi [40]. All studies support our hypothesis that mechanical properties of

• important parameter. Tissue distribution and blood circulation Independent of the application route, blood circulation and tissue distribution are important factors regarding the fate of nanoparticles in vivo. The plasma half-life time is not only important for a sustained release but also to enhance the

Curcumin-loaded albumin submicron particles with potential as a cancer therapy: an in vitro study

• Nittiya Suwannasom,
• Netsai Sriaksorn,
• Chutamas Thepmalee,
• Krissana Khoothiam,
• Ausanai Prapan,
• Hans Bäumler and
• Chonthida Thephinlap

Beilstein J. Nanotechnol. 2023, 14, 1127–1140, doi:10.3762/bjnano.14.93

• and migration of C6 glioma cells in vitro [12]. Other nanoparticles that are being explored as CUR formulations for various applications include silk-based nanoparticles. These are an excellent candidate with longer plasma half-life and slower release rate, indicating high bioavailability [13]. The

Properties of tin oxide films grown by atomic layer deposition from tin tetraiodide and ozone

• Kristjan Kalam,
• Peeter Ritslaid,
• Tanel Käämbre,
• Aile Tamm and
• Kaupo Kukli

Beilstein J. Nanotechnol. 2023, 14, 1085–1092, doi:10.3762/bjnano.14.89

• -propoxide)Sn as the Sn precursor and either H2O plasma or O2 plasma as the oxygen source [23]. Refractive index values between 2.0 and 2.1, comparable to those measured in the present study, have been obtained in a paper reporting the results of thermal ALD of SnO2 from tetrakis(dimethylamino)tin as the Sn

Recognition mechanisms of hemoglobin particles by monocytes – CD163 may just be one

• Jonathan-Gabriel Nimz,
• Pichayut Rerkshanandana,
• Chiraphat Kloypan,
• Ulrich Kalus,
• Saranya Chaiwaree,
• Axel Pruß,
• Radostina Georgieva,
• Yu Xiong and
• Hans Bäumler

Beilstein J. Nanotechnol. 2023, 14, 1028–1040, doi:10.3762/bjnano.14.85

• emerging hydrogen bonds, altered surface structures, and possible interactions between proteins and particles, in particular polymers such as HbMPs [45][46]. The adsorption of various plasma proteins seems to not only enhance the chance of complement activation but also to promote phagocytosis directly, as

• sequestration as the HSA on the surface of our particles has shown to attenuate the adsorption of plasma proteins [19]. Kloypan et al. observed granulocytic uptake of albumin-based particles in an indirect phagocytosis assay [22]. An observation that was made repeatedly in the present study. Thus, it appears

Fragmentation of metal(II) bis(acetylacetonate) complexes induced by slow electrons

• Janina Kopyra and
• Hassan Abdoul-Carime

Beilstein J. Nanotechnol. 2023, 14, 980–987, doi:10.3762/bjnano.14.81

• beams), in plasma applications, or possibly in radiation therapy as radiosensitizers. Experimental We performed electron collision experiments with several metal acetylacetonate compounds, ML2, in a crossed-beam arrangement. According to the description given in [16][17][29], this arrangement consists

Isolation of cubic Si₃P₄ in the form of nanocrystals

• Polina K. Nikiforova,
• Sergei S. Bubenov,
• Vadim B. Platonov,
• Andrey S. Kumskov,
• Nikolay N. Kononov,
• Tatyana A. Kuznetsova and
• Sergey G. Dorofeev

Beilstein J. Nanotechnol. 2023, 14, 971–979, doi:10.3762/bjnano.14.80

• Si3P4 phase. Also worth noting was that the synthesis of cubic Si3P4 NPs could be performed immediately after laser-induced or plasma-enhanced chemical vapor deposition of nanosilicon from the silane precursor (since the NPs obtained this way are readily hydrogenated). Additionally, there is preliminary

Low temperature atomic layer deposition of cobalt using dicobalt hexacarbonyl-1-heptyne as precursor

• Mathias Franz,
• Mahnaz Safian Jouzdani,
• Lysann Kaßner,
• Marcus Daniel,
• Frank Stahr and
• Stefan E. Schulz

Beilstein J. Nanotechnol. 2023, 14, 951–963, doi:10.3762/bjnano.14.78

• operates at low temperatures using dicobalt hexacarbonyl-1-heptyne [Co2(CO)6HC≡CC5H11] and hydrogen plasma. For this precursor an ALD window in the temperature range between 50 and 110 °C was determined with a constant deposition rate of approximately 0.1 Å/cycle. The upper limit of the ALD window is

• -temperature ALD; PEALD; plasma-enhanced ALD; XPS; Introduction The atomic layer deposition (ALD) of cobalt films is an ongoing topic of interest [1]. Cobalt thin and ultrathin films play an important role in current generations of integrated circuits [2]. Compared to copper, the metal offers a greater

• for the deposition of metallic cobalt including twelve plasma-assisted processes. Generally, these plasma-assisted ALD processes are reported to be carried out at temperatures above 100 °C. These processes use precursors such as CoCp2, Co(EtCp)2, or CpCo(CO)2 [12][13][14]. The commonly used precursor

Upscaling the urea method synthesis of CoAl layered double hydroxides

• Camilo Jaramillo-Hernández,
• Víctor Oestreicher,
• Martín Mizrahi and
• Gonzalo Abellán

Beilstein J. Nanotechnol. 2023, 14, 927–938, doi:10.3762/bjnano.14.76

• Figure S11, Supporting Information File 1) [30][52][55]. TGA curves in inert atmosphere can be found in Supporting Information File 1, Figure S12. Inductively coupled plasma mass spectrometry (ICP-MS) was employed to assess quantitatively the precipitation of the cations. It confirmed a Co/Al ratio of

Antibody-conjugated nanoparticles for target-specific drug delivery of chemotherapeutics

• Mamta Kumari,
• Amitabha Acharya and
• Praveen Thaggikuppe Krishnamurthy

Beilstein J. Nanotechnol. 2023, 14, 912–926, doi:10.3762/bjnano.14.75

• prevent or minimize the corona formation. Precoating of NPs with specific proteins that increase the adsorption of plasma proteins with intrinsic targeting capacities also improve the targeting ability of the NPs. Moreover, researchers demonstrated that attachment of targeting moieties on the surface of

Green SPIONs as a novel highly selective treatment for leishmaniasis: an in vitro study against Leishmania amazonensis intracellular amastigotes

• Brunno R. F. Verçoza,
• Robson R. Bernardo,
• Luiz Augusto S. de Oliveira and
• Juliany C. F. Rodrigues

Beilstein J. Nanotechnol. 2023, 14, 893–903, doi:10.3762/bjnano.14.73

• , scanning electron microscopy and chemical element mapping analysis were carried out to confirm the uptake of the SPIONs by L. amazonensis intracellular amastigotes after removing the plasma membrane to expose the cytoplasmic environment (Figure 2). Secondary electron imaging revealed intracellular

• macrophage cytosol, the parasitophorous vacuoles, and the amastigote cytosol (arrowheads). Scanning electron microscopy of macrophages infected with L. amazonensis intracellular amastigotes after treatment with 100 µg/mL SPIONs for 24 h. The plasma membrane was gently removed to observe the presence of

Silver-based SERS substrates fabricated using a 3D printed microfluidic device

• Phommachith Sonexai,
• Minh Van Nguyen,
• Bui The Huy and
• Yong-Ill Lee

Beilstein J. Nanotechnol. 2023, 14, 793–803, doi:10.3762/bjnano.14.65

• from the mold. There are various surface treatment methods available, including oxygen plasma, UV/ozone, corona oxidizer, and plasma pen [46][47]. In this study, we employed a previously reported chemical treatment method that uses 1 M NaOH solution for 24 h [48]. Although this method takes longer, it

Titania nanoparticles for photocatalytic degradation of ethanol under simulated solar light

• Evghenii Goncearenco,
• Iuliana P. Morjan,
• Claudiu Teodor Fleaca,
• Florian Dumitrache,
• Elena Dutu,
• Monica Scarisoreanu,
• Valentin Serban Teodorescu,
• Alexandra Sandulescu,
• Crina Anastasescu and
• Ioan Balint

Beilstein J. Nanotechnol. 2023, 14, 616–630, doi:10.3762/bjnano.14.51

• Evghenii Goncearenco Iuliana P. Morjan Claudiu Teodor Fleaca Florian Dumitrache Elena Dutu Monica Scarisoreanu Valentin Serban Teodorescu Alexandra Sandulescu Crina Anastasescu Ioan Balint National Institute for Lasers, Plasma and Radiation Physics, Atomistilor Str., No. 409, 077125, Bucharest