Nanocarrier-integrated multilayer films produced by 3D printing for improved skin adhesion and curcumin photostability

• Thayse Viana de Oliveira,
• Ana Paula Farias Leão,
• Júlia Leão,
• Cesar Liberato Petzhold and
• Ruy Carlos Ruver Beck

Beilstein J. Nanotechnol. 2026, 17, 440–453, doi:10.3762/bjnano.17.30

• restricting molecular mobility and reducing direct light exposure within the matrix. However, the most pronounced protective effect was clearly associated with the presence of the TiO2-containing layer, indicating that spatial separation of functions enabled by multilayer 3D printing is critical for achieving

• the spatial separation of adhesion, drug delivery, and photoprotection functions, representing a significant advance over conventional single-layer topical films. Regarding rheological properties, both yield stress and complex viscosity were estimated using an oscillatory amplitude sweep test. Yield

Biomimetic nanoparticles in cancer photodynamic therapy: a review of targeted delivery systems and therapeutic outcomes

• Valentina I. Gorbacheva,
• Alexey S. Grabovoy,
• Polina S. Marukhina,
• Anastasiia O. Syrocheva and
• Ekaterina P. Kolesova

Beilstein J. Nanotechnol. 2026, 17, 396–422, doi:10.3762/bjnano.17.27

Polycatecholamine nanocoatings on stainless steel: the effect on attachment of human fibroblasts and platelets

• Paulina Trzaskowska,
• Ewa Rybak,
• Maciej Trzaskowski,
• Kamil Kopeć,
• Jakub Krzemiński,
• Rafał Podgórski,
• Hatice Genc,
• Mehtap Civelek and
• Iwona Cicha

Beilstein J. Nanotechnol. 2026, 17, 365–380, doi:10.3762/bjnano.17.25

• immediately after PRP separation. Samples were incubated for 90 min at 37 °C and 5% CO2. Following the incubation process, samples were washed several times with PBS to remove the unattached platelets and fixed 4% buffered paraformaldehyde. Platelet visualization was performed using an ultrahigh-resolution

Ferroelectric nanodot reservoir for neuromorphic computing

• Anna Razumnaya,
• Yuri Tikhonov,
• Dmitrii Naidenko,
• Léo Boron,
• Valerii Vinokur and
• Igor Lukyanchuk

Beilstein J. Nanotechnol. 2026, 17, 352–364, doi:10.3762/bjnano.17.24

• changes in the input sequence (field trajectory) can cause large and qualitatively different polarization responses. This sensitivity enables powerful separation of input classes in the reservoir state space. (ii) Short-term memory. The system retains a history of past field variations through its current

Beam shaping techniques for pulsed laser ablation in liquids: Unlocking tunable control of nanoparticle synthesis in liquids

• Sergio Molina-Prados,
• Nadezhda M. Bulgakova,
• Alexander V. Bulgakov,
• Jesus Lancis,
• Gladys Mínguez Vega and
• Carlos Doñate-Buendia

Beilstein J. Nanotechnol. 2026, 17, 309–342, doi:10.3762/bjnano.17.22

• mass in suspension. Incomplete solvent evaporation or residual organics can bias gravimetric results, making vacuum drying preferable. NP adhesion to container walls requires vessel washing, and aggregation during or after ablation may need sonication or size-separation steps. Overall, gravimetry

Advancing nanolithography: a comprehensive review of materials for local anodic oxidation with AFM

• Matteo Lorenzoni

Beilstein J. Nanotechnol. 2026, 17, 275–291, doi:10.3762/bjnano.17.19

• preparation steps, LAO enables direct chemical modification, with precise control of the tip–sample separation during the writing process. This is typically achieved in contact mode, where the tip apex is in direct contact with the substrate, ensuring capillary condensation and the formation of a stable water

Comparative study on 3D morphologies of delignified, single tracheids and fibers of five wood species

• Helen Gorges,
• Felicitas von Usslar,
• Cordt Zollfrank,
• Silja Flenner,
• Imke Greving,
• Martin Müller,
• Clemens F. Schaber,
• Chuchu Li and
• Stanislav N. Gorb

Beilstein J. Nanotechnol. 2026, 17, 239–250, doi:10.3762/bjnano.17.16

• resulted in facilitated separation of fibers and tracheids and frayed wall appearance. We observed similar tracheid/fiber diameters and wall thicknesses for all five wood species. These findings enhance our understanding of the wood fiber and tracheid structures across species and the effects of

• adapt to various environments [48][49], while balsa trees favor tropical and subtropical climates [50]. Across all wood types studied, delignification results into (1) facile separation of fibers and tracheids with visible spaces between neighboring walls (removal of the lignin-rich middle lamella) and

Gold nanoparticle-decorated reduced graphene oxide as a highly effective catalyst for the selective α,β-dehydrogenation of N-alkyl-4-piperidones

• Brenda Flore Kenyim,
• Mihir Tzalis,
• Marilyn Kaul,
• Robert Oestreich,
• Aysenur Limon,
• Chancellin Pecheu Nkepdep and
• Christoph Janiak

Beilstein J. Nanotechnol. 2026, 17, 218–238, doi:10.3762/bjnano.17.15

• -metal nanoparticles in heterogeneous catalysis is their separation from the reaction mixture for re-use or recycling, and also to avoid contamination of the products. The difficulty in separating small nanoparticles demands for the efficient and easy formation of a composite that can be separated by

• be suitable for long-term reactions. Although it exhibits a slower reaction rate due to the preparation method as discussed earlier, it maintains a more consistent catalytic activity over time than Au-Cit/rGO. An important aspect of the AuNP heterogenization on a carbon support is the separation

Influence of surface characteristics on the in vitro stability and cell uptake of nanoliposomes for brain delivery

• Dushko Shalabalija,
• Ljubica Mihailova,
• Nikola Geskovski,
• Andreas Zimmer,
• Otmar Geiss,
• Sabrina Gioria,
• Diletta Scaccabarozzi and
• Marija Glavas Dodov

Beilstein J. Nanotechnol. 2026, 17, 139–158, doi:10.3762/bjnano.17.9

• for asymmetric flow field-flow fractionation analysis (AF4 analysis). Experiments were carried out by in-line coupling the AF4 system with UV–vis, multi-angle light scattering (MALS), and dynamic light scattering (DLS) detectors. The AF4 system used was composed of an Eclipse Dualtec separation system

• nm. In the Eclipse SC separation channel, regenerated cellulose membranes (10 kDa) and a spacer height of 350 μm were used. Phosphate buffer was used as the eluent. The detector flow rate was set to 0.5 mL/min and the injection volume was 50 µL. The separation settings were: a) elution 0–3 min; b

• intensive but excels in fractionating samples under optimal flow and separation conditions. This method is distinguished by gentle separation conditions and a wide operational range. Unlike conventional chromatography, AF4 does not utilize a stationary phase. The separation mechanism involves a longitudinal

Microscopic study of the intermediate mixed state in intertype superconductors

• Vyacheslav D. Neverov,
• Alexander V. Kalashnikov,
• Andrey V. Krasavin and
• Alexei Vagov

Beilstein J. Nanotechnol. 2026, 17, 57–62, doi:10.3762/bjnano.17.5

• (T = 0.9Tc), vortices form an equilateral triangle with maximal inter-vortex separation, which is typical for type-II superconductivity. As the temperature decreases to T = 0.1Tc, the triangular arrangement persists, but the inter-vortex distance shrinks, indicating the appearance of a minimum in the

• = 3.6, shown in the middle row of Figure 1, corresponds to the boundary between the two different IT regimes. In this case, vortices form an equilateral triangle, revealing the IT character of the vortex state at all the temperatures considered. However, the inter-vortex separation is smaller than that

Quantitative estimation of nanoparticle/substrate adhesion by atomic force microscopy

• Aydan Çiçek,
• Markus Kratzer,
• Christian Teichert and
• Christian Mitterer

Beilstein J. Nanotechnol. 2026, 17, 1–14, doi:10.3762/bjnano.17.1

• manipulation. It should be noted that the derived values for the total work of manipulation include both the actual work of separation Wsep and the dissipated work Wdiss, which does not contribute to the separation. The relationship can be expressed as: NP motion on a surface may not necessarily proceed as an

• manipulation as a first approximation for the work of adhesion as the details in the process of manipulation are rather complex including adhesion, static and dynamic friction, and humidity [49]. Due to the challenges in direct calculation of the dissipated work, the work of separation is approximated using

• the following equation: where Fstatic is the maximum static lateral force, Fcap represents the capillary force, and Fn is the normal force applied by the cantilever. μ is the coefficient of friction and ls the separation distance given by the distance between the first tip/NP contact and the position

Improving magnetic properties of Mn- and Zn-doped core–shell iron oxide nanoparticles by tuning their size

• Dounia Louaguef,
• Ghouti Medjahdi,
• Sébastien Diliberto,
• Klaus M. Seemann,
• Thomas Gries,
• Joelle Bizeau,
• Damien Mertz,
• Eric Gaffet and
• Halima Alem

Beilstein J. Nanotechnol. 2025, 16, 2285–2295, doi:10.3762/bjnano.16.157

• unique magnetic properties, small size, and biocompatibility, which enable them to be used in a wide range of biomedical applications. These applications include magnetic resonance imaging, magnetic separation, targeted drug delivery, and hyperthermia [1][2]. Magnetic hyperthermia has been extensively

Visualizing nanostructures in supramolecular hydrogels: a correlative study using confocal and cryogenic scanning electron microscopy

• Shaun M. Smith,
• Ferdinando Malagreca,
• Jacqueline Hicks,
• Giuseppe Mantovani,
• David B. Amabilino,
• Christopher Parmenter and
• Lluïsa Pérez-García

Beilstein J. Nanotechnol. 2025, 16, 2274–2284, doi:10.3762/bjnano.16.156

• result in phase separation whereby the water freezes, first expelling the ethanol into concentrated domains, which alters microscale material morphology. Such a phenomenon has been exploited for the fractional freezing of water–ethanol mixtures and in liposomal formulations containing water and DMSO [36

Chiral plasmonic nanostructures fabricated with circularly polarized light

• Tian Qiao and
• Ming Lee Tang

Beilstein J. Nanotechnol. 2025, 16, 2245–2264, doi:10.3762/bjnano.16.154

• to treat morning sickness in pregnant women. One of its enantiomers was found to have sedative effects, while the other was identified as teratogenic, leading to tragic consequences, including over 10,000 severe birth defects in children [4][5][6][7][8]. Promoting the separation and detection of

• [13]. In 1848, Pasteur achieved the physical separation of enantiomers for the first time. In his experiments, he crystallized the racemic sodium ammonium salt of tartaric acid, forming two distinct crystals that each rotated the polarization of light in opposite manner [14]. The interaction between

• immobilized should be carefully explored to enhance charge separation and achieve better distribution dissymmetry of hot carriers. These insights will also be valuable for integrating CPL with chiral molecular templates for growing cPNSs. (ii) Periodic arrays of cPNSs can be fabricated using CPL on a

Microplastic pollution in Himalayan lakes: assessment, risks, and sustainable remediation strategies

• Sameeksha Rawat,
• S. M. Tauseef and
• Madhuben Sharma

Beilstein J. Nanotechnol. 2025, 16, 2144–2167, doi:10.3762/bjnano.16.148

• using pretreatment techniques such as enzymatic decomposition of organic matter and density separation using saline solutions. These processes, however, might take a lot of time and could cause tiny particles to be lost [32]. The distinct combination of nanoscale dimensions and very low concentration in

• them are new electrochemical technologies, membrane separation technologies, microbial technologies, and AOPs. The efficiency, mechanism, strengths, weaknesses, and applications of each technology are utilized to assess each technology. These technologies are indicative of the multidimensional

Quality by design optimization of microemulsions for topical delivery of Passiflora setacea seed oil

• Daniel T. Pereira,
• Douglas Dourado,
• Danielle T. Freire,
• Dayanne L. Porto,
• Cícero F. S. Aragão,
• Myla L. de Souza,
• Guilherme R. S. de Araujo,
• Ana Maria Costa,
• Wógenes N. Oliveira,
• Anne Sapin-Minet,
• Éverton N. Alencar and
• Eryvaldo Sócrates T. Egito

Beilstein J. Nanotechnol. 2025, 16, 2116–2131, doi:10.3762/bjnano.16.146

• issue in emulsified systems is microbial contamination, which can result in physical and chemical instability, such as pH shifts, turbidity, degradation of active components (e.g., fatty acids), and phase separation [35]. To address these challenges and improve topical suitability, additional excipients

• methanolic potassium hydroxide. The base-catalyzed transesterification reaction was carried out at 60 °C for 15 min. After cooling, the reaction was quenched with 20 µL of acetic acid. To extract the FAMEs, 1 mL of n-hexane and water were added, followed by vigorous agitation. Once phase separation occurred

• visual appearance (e.g. signs of haze, creaming, or phase separation), hydrodynamic diameter distribution, and pH. The pH was measured using a pre-calibrated PG 2000 pH meter (Gehaka, São Paulo, Brazil). Due to its high viscosity, MEgel samples were diluted with purified water (1:40 w/w) prior to

Multifrequency AFM integrating PeakForce tapping and higher eigenmodes for heterogeneous surface characterization

• Yanping Wei,
• Jiafeng Shen,
• Yirong Yao,
• Xuke Li,
• Ming Li and
• Peiling Ke

Beilstein J. Nanotechnol. 2025, 16, 2077–2085, doi:10.3762/bjnano.16.142

• and electronic signal separation enables simultaneous, effective acquisition of quasi-static force maps and eigenmode-derived material contrast. Dual-probe comparative analysis of MMT nanosheets The effectiveness of the method was evaluated using the soft (ScanAsyst-Air, 0.48 N·m−1) and stiff (NSC15

• thicker nanosheet regions used for the reported histograms, and Ashman’s D values were computed for both Young’s modulus and phase signals using the method described in [25] (Table 3). D > 2 indicates clear separation of distributions. Modulus maps reveal probe-dependence; the soft probe fails to provide

• reliable separation, while the stiff probe successfully discriminates (D ≈ 2.7). However, phase imaging with both probes enables effective differentiation between these regions, demonstrating that the eigenmode contrast is less dependent on probe stiffness compared to quantitative mechanics maps. To assess

Molecular and mechanical insights into gecko seta adhesion: multiscale simulations combining molecular dynamics and the finite element method

• Yash Jain,
• Saeed Norouzi,
• Tobias Materzok,
• Stanislav N. Gorb and
• Florian Müller-Plathe

Beilstein J. Nanotechnol. 2025, 16, 2055–2076, doi:10.3762/bjnano.16.141

• detachment occurred. Just before detachment, the tip’s and pad’s X-coordinates decreased slightly, suggesting a minor slide towards −X before the spatula completely detached. At detachment, there was a sudden increase in the tip’s Y-coordinate, marking separation from the substrate. After detachment, the

Stereodiscrimination of guests in chiral organosilica aerogels studied by ESR spectroscopy

• Sebastian Polarz,
• Yasar Krysiak,
• Martin Wessig and
• Florian Kuhlmann

Beilstein J. Nanotechnol. 2025, 16, 2034–2054, doi:10.3762/bjnano.16.140

• the chromatographic separation of enantiomers. Despite these materials being highly engineered and commercially available, optimization was often done empirically. A rational design of future and improved solid phases for chiral chromatography requires that one understands how the chemical structure

• necessary to reach separation is an important point. We have employed the two enantiomers of a chiral, nitroxide-based spin probe as guests in organo-modified macroporous host materials and applied ESR spectroscopy as a tool to investigate their rotational mobility. Using a well-established and commercially

• adapted for chiral separations, providing robust, reproducible methods for enantiomeric resolution. Chiral chromatography is a pivotal technique in the separation and analysis of chiral compounds, particularly in the pharmaceutical industry, where the distinction between different enantiomers of a

Laser ablation in liquids for shape-tailored synthesis of nanomaterials: status and challenges

• Natalie Tarasenka

Beilstein J. Nanotechnol. 2025, 16, 1963–1997, doi:10.3762/bjnano.16.137

Targeting the vector of arboviruses Aedes aegypti with nanoemulsions based on essential oils: a review with focus on larvicidal and repellent properties

• Laryssa Ferreira do Nascimento Silva,
• Douglas Dourado,
• Thayse Silva Medeiros,
• Mariana Alice Gonzaga Gabú,
• Maria Cecilia Queiroga dos Santos,
• Daiane Rodrigues dos Santos,
• Mylena Lemos dos Santos,
• Gabriel Bezerra Faierstein,
• Rosângela Maria Rodrigues Barbosa and
• Fabio Rocha Formiga

Beilstein J. Nanotechnol. 2025, 16, 1894–1913, doi:10.3762/bjnano.16.132

• ultrasonication (40 kHz). This formulation demonstrated physicochemical stability, with good optical transparency and absence of phase separation. Characterization by TEM revealed spherical droplets with sizes between 20 and 40 nm. In the larvicidal bioassay, fourth-instar larvae of Ae. aegypti were exposed to

Low-temperature AFM with a microwave cavity optomechanical transducer

• Ermes Scarano,
• Elisabet K. Arvidsson,
• August K. Roos,
• Erik Holmgren,
• Riccardo Borgani,
• Mats O. Tholén and
• David B. Haviland

Beilstein J. Nanotechnol. 2025, 16, 1873–1882, doi:10.3762/bjnano.16.130

• resonant circuit. While slightly degrading the performance of the displacement detector, this effect has the advantage of providing an easily measurable indication of probe–surface separation during coarse approach. For the final stage of the approach, we drive the z-scanner with a DC voltage (100 nm/V

Current status of using adsorbent nanomaterials for removing microplastics from water supply systems: a mini review

• Nguyen Thi Nhan and
• Tran Le Luu

Beilstein J. Nanotechnol. 2025, 16, 1837–1850, doi:10.3762/bjnano.16.127

• process. According to Goel et al., the physical methods primarily rely on magnetic separation, while chemical approaches focus on nanoparticle functionalization to improve their effectiveness in microplastic removal [74]. Accordingly, numerous magnetic nanomaterials have been investigated and modified to

• a magnetic nanoseed concentration of just 0.002 g·L−1, these composites enabled 98% PET extraction, with the separation efficiency largely influenced by the morphology of the magnetic seeds. In addition to ensuring highly efficient magnetic separation of MP particles, this approach significantly

• reduced the volume of synthetic flocculant sludge [76]. By applying magnetic Fe3O4 nanoparticles, 83.1–92.9% of MPs with particle sizes ranging from 100 to 1000 nm were removed thanks to adsorption with magnetic separation [77]. These mechanisms are influenced significantly by factors like pH, ionic

Phytol-loaded soybean oil nanoemulsion as a promising alternative against Leishmania amazonensis

• Victória Louise Pinto Freire,
• Mariana Farias Alves-Silva,
• Johny W. de Freitas Oliveira,
• Matheus de Freitas Fernandes-Pedrosa,
• Alianda Maira Cornélio,
• Marcelo de Souza-Silva,
• Thayse Silva Medeiros and
• Arnóbio Antônio da Silva Junior

Beilstein J. Nanotechnol. 2025, 16, 1826–1836, doi:10.3762/bjnano.16.126

• incorporation of poloxamer 407 increased the viscosity of the external aqueous phase, thereby reducing Brownian motion and droplet collision frequency – mechanisms that are often associated with delayed creaming and phase separation [42][43]. Taken together, these compositional strategies demonstrate the

Piezoelectricity of layered double hydroxides: perspectives regarding piezocatalysis and nanogenerators

• Evgeniy S. Seliverstov,
• Evgeniya A. Tarasenko and
• Olga E. Lebedeva

Beilstein J. Nanotechnol. 2025, 16, 1812–1817, doi:10.3762/bjnano.16.124

• and external stress, leading to increased current generation and reactive oxygen species production. The authors proposed that the piezoelectric field of LDHs facilitates the separation of photo-induced electron–hole pairs and modulates band alignment, thereby synergistically enhancing the piezo

• parameters, reduced thickness, cationic flexibility, and heterostructure formation, emerge as recurring factors that enhance charge separation and local polarization. Thus, the idea that LDHs can act not only as passive hosts but also as active piezoelectric components is supported by all mentioned works. At