Ultrathin water layers on mannosylated gold nanoparticles

• Maiara A. Iriarte Alonso,
• Jorge H. Melillo,
• Silvina Cerveny,
• Yujin Tong and
• Alexander M. Bittner

Beilstein J. Nanotechnol. 2025, 16, 2183–2198, doi:10.3762/bjnano.16.151

• nanoparticle systems, one functionalized with an oligo(ethylene glycol) ligand, and one functionalized with a mixture of the same with a dimannoside ligand. The dimannoside ligand was chosen to mimic the surface chemistry of viral spike proteins. We characterized the particles by electron microscopy, dynamic

Rapid synthesis of highly monodisperse AgSbS₂ nanocrystals: unveiling multifaceted activities in cancer therapy, antibacterial strategies, and antioxidant defense

• Funda Ulusu,
• Adem Sarilmaz,
• Yakup Ulusu,
• Faruk Ozel and
• Mahmut Kus

Beilstein J. Nanotechnol. 2025, 16, 2105–2115, doi:10.3762/bjnano.16.145

• ratio and enhanced surface reactivity [30]. These features, combined with the tunable surface chemistry of nanoparticles, allow for efficient interactions with free radicals and facilitate electron transfer reactions, resulting in robust antioxidant activity [49]. This activity involves scavenging free

• scavenging data, the FRAP outcome supports a dual-mechanism antioxidant model (both radical quenching and electron transfer). This suggests that the surface chemistry of AgSbS2 NCs effectively mediates both redox and radical-based pathways, making them promising candidates for applications requiring moderate

Toward clinical translation of carbon nanomaterials in anticancer drug delivery: the need for standardisation

• Michał Bartkowski,
• Francesco Calzaferri and
• Silvia Giordani

Beilstein J. Nanotechnol. 2025, 16, 2092–2104, doi:10.3762/bjnano.16.144

• nanotubes, and carbon dots, have attracted considerable interest as nanocarriers for drug delivery due to their unique physicochemical properties. Their high surface area, biocompatibility, and modifiable surface chemistry make them highly attractive for a range of biomedical applications. However, concerns

• affairs. Achieving these key milestones is critical to developing a safe and effective drug delivery system that can improve the treatment of cancer. The process begins with the synthesis of CNMs tailored to specific size and surface chemistry requirements, using methods such as chemical vapour deposition

• safety. Insights from these studies guide further optimisation of the delivery system, which may involve adjusting particle size, surface chemistry, or drug-loading strategies. Once optimised and evaluated, the system enters regulatory review, requiring preclinical safety and efficacy data to meet

Molecular and mechanical insights into gecko seta adhesion: multiscale simulations combining molecular dynamics and the finite element method

• Yash Jain,
• Saeed Norouzi,
• Tobias Materzok,
• Stanislav N. Gorb and
• Florian Müller-Plathe

Beilstein J. Nanotechnol. 2025, 16, 2055–2076, doi:10.3762/bjnano.16.141

• microscopy (AFM) experiments. Our investigation into how gecko keratin interacts with hydrophilic and hydrophobic substrates [12] supported the importance of the water-mediating effect [10] and elucidated mechanistic differences depending on surface chemistry. A particle-based mesoscale model of a single

Ambient pressure XPS at MAX IV

• Mattia Scardamaglia,
• Ulrike Küst,
• Alexander Klyushin,
• Rosemary Jones,
• Jan Knudsen,
• Robert Temperton,
• Andrey Shavorskiy and
• Esko Kokkonen

Beilstein J. Nanotechnol. 2025, 16, 1677–1694, doi:10.3762/bjnano.16.118

• photoexcited holes migrate to NiO and are trapped, facilitating water oxidation via an intermediate NiOOH species (Figure 10b). APXPS thereby provides mechanistic insight into photoinduced surface chemistry, enabling rational catalyst design. Similar approaches can be extended to CO2 reduction, pollutant

• surface chemistry have come from ex situ or in vacuo XPS, often complemented by other surface characterization tools, used to characterize the resulting film [49][50][51], as well as to investigate chemical mechanisms cycle-to-cycle [51][52]; the latter procedure is often termed in situ XPS. However, such

Nanotechnology-based approaches for the removal of microplastics from wastewater: a comprehensive review

• Nayanathara O Sanjeev,
• Manjunath Singanodi Vallabha and
• Rebekah Rubidha Lisha Rabi

Beilstein J. Nanotechnol. 2025, 16, 1607–1632, doi:10.3762/bjnano.16.114

• , and advanced membrane materials, exhibit unique properties such as high surface area, enhanced reactivity, and tunable surface chemistry, which offer promising avenues for the selective and efficient removal of MPs from water. This paper also explores the mechanism, performance and limitations of

• thermal, acidic, and saline conditions. Its self-adhesive nature, biocompatibility, and durability make it a promising preventive strategy at the source. Similarly, nanocellulose, derived from renewable biomass, exhibits a high surface area and tunable surface chemistry, making it effective for adsorbing

Nanomaterials for biomedical applications

• Iqra Zainab,
• Zohra Naseem,
• Syeda Rubab Batool,
• Filippo Pierini,
• Seda Kizilel and
• Muhammad Anwaar Nazeer

Beilstein J. Nanotechnol. 2025, 16, 1499–1503, doi:10.3762/bjnano.16.105

• . Nanomaterials have gained popularity in medicine because they can be altered according to the need [1]. Researchers can tailor the shape, surface chemistry, and other specific properties of materials to deliver desirable traits. In particular, some nanoparticles can be used to deliver drugs to a tumor, reducing

Laser processing in liquids: insights into nanocolloid generation and thin film integration for energy, photonic, and sensing applications

• Akshana Parameswaran Sreekala,
• Pooja Raveendran Nair,
• Jithin Kundalam Kadavath,
• Bindu Krishnan,
• David Avellaneda Avellaneda,
• M. R. Anantharaman and
• Sadasivan Shaji

Beilstein J. Nanotechnol. 2025, 16, 1428–1498, doi:10.3762/bjnano.16.104

Enhancing the therapeutical potential of metalloantibiotics using nano-based delivery systems

• Alejandro Llamedo,
• Marina Cano,
• Raquel G. Soengas and
• Francisco J. García-Alonso

Beilstein J. Nanotechnol. 2025, 16, 1350–1366, doi:10.3762/bjnano.16.98

• ]. Dendrimers, with their hyperbranched structures, can be precisely controlled for size, shape, and surface chemistry, allowing for highly targeted delivery of anti-biofilms drugs or nucleic acids [81][82]. Polymeric NPs offer several advantages, including biodegradability, biocompatibility, and stability

Enhancing the photoelectrochemical performance of BiOI-derived BiVO₄ films by controlled-intensity current electrodeposition

• Huu Phuc Dang,
• Khanh Quang Nguyen,
• Nguyen Thi Mai Tho and
• Tran Le

Beilstein J. Nanotechnol. 2025, 16, 1289–1301, doi:10.3762/bjnano.16.94

• . Larger grains typically result in fewer grain boundaries, reducing phonon scattering and enhancing vibrational coherence. Raman spectra also provide insights into the influence of fabrication conditions on surface chemistry. The relative intensities of the peaks suggest that higher deposition currents

Characterization of ion track-etched conical nanopores in thermal and PECVD SiO₂ using small angle X-ray scattering

• Shankar Dutt,
• Rudradeep Chakraborty,
• Christian Notthoff,
• Pablo Mota-Santiago,
• Christina Trautmann and
• Patrick Kluth

Beilstein J. Nanotechnol. 2025, 16, 899–909, doi:10.3762/bjnano.16.68

• dioxide [29][40][30]. Amorphous silicon dioxide (SiO2) has excellent chemical stability, well-understood surface chemistry, and compatibility with semiconductor processing, opening up new applications for track-etched nanopores in this material [30]. In this study, we report the characterization of track

Insights into the electronic and atomic structures of cerium oxide-based ultrathin films and nanostructures using high-brilliance light sources

• Paola Luches and
• Federico Boscherini

Beilstein J. Nanotechnol. 2025, 16, 860–871, doi:10.3762/bjnano.16.65

• under UHV conditions. Such instruments, installed at synchrotron radiation facilities and applied to ceria-based model systems have given an important contribution to understanding the surface chemistry of specific reactions. Coexisting Pt and ceria nanoparticles supported on TiO2(110) were found to

Colloidal few layered graphene–tannic acid preserves the biocompatibility of periodontal ligament cells

• Teissir Ben Ammar,
• Naji Kharouf,
• Dominique Vautier,
• Housseinou Ba,
• Nivedita Sudheer,
• Philippe Lavalle and
• Vincent Ball

Beilstein J. Nanotechnol. 2025, 16, 664–677, doi:10.3762/bjnano.16.51

• . The cellular response on different graphene surfaces was previously studied, and it was demonstrated that substrate characteristics such as surface roughness, surface chemistry, and electronic properties can influence cell response [38]. The implications of these results are particularly significant

Nanomaterials in targeting amyloid-β oligomers: current advances and future directions for Alzheimer's disease diagnosis and therapy

• Shiwani Randhawa,
• Trilok Chand Saini,
• Manik Bathla,
• Rahul Bhardwaj,
• Rubina Dhiman and
• Amitabha Acharya

Beilstein J. Nanotechnol. 2025, 16, 561–580, doi:10.3762/bjnano.16.44

• nm AuNPs either accelerated fibril formation or had little impact on peptide aggregation [96]. In conclusion, these studies underscore the critical role of nanoparticle size, shape, and surface chemistry in modulating amyloid aggregation and inhibition. Smaller nanoparticles, particularly those

Impact of adsorbate–substrate interaction on nanostructured thin films growth during low-pressure condensation

• Alina V. Dvornichenko,
• Vasyl O. Kharchenko and
• Dmitrii O. Kharchenko

Beilstein J. Nanotechnol. 2025, 16, 473–483, doi:10.3762/bjnano.16.36

• , crystallinity, and surface chemistry of the films is crucial for optimizing performance in these applications. In adsorption–desorption processes, where materials are deposited from the gas phase, experimental techniques enable the study the formation of clusters or islands of adsorbed molecules/atoms, which

Engineered PEG–PCL nanoparticles enable sensitive and selective detection of sodium dodecyl sulfate: a qualitative and quantitative analysis

• Soni Prajapati and
• Ranjana Singh

Beilstein J. Nanotechnol. 2025, 16, 385–396, doi:10.3762/bjnano.16.29

• larger estimate than the dry measurements obtained from TEM and SEM [32]. X-ray photoelectron spectroscopy, also known as electron spectroscopy for chemical analysis (ESCA), was used to analyze the surface chemistry of the PEG–PCL NPs. XPS is a powerful surface-sensitive technique that provides detailed

Emerging strategies in the sustainable removal of antibiotics using semiconductor-based photocatalysts

• Yunus Ahmed,
• Keya Rani Dutta,
• Parul Akhtar,
• Md. Arif Hossen,
• Md. Jahangir Alam,
• Obaid A. Alharbi,
• Hamad AlMohamadi and
• Abdul Wahab Mohammad

Beilstein J. Nanotechnol. 2025, 16, 264–285, doi:10.3762/bjnano.16.21

• sites, slow kinetics of surface reactions, and the reduced mobility of charges, resulting in electron delocalization [99][100]. The molecular rearrangement of g-C3N4 has been the subject of recent research because of its potential to alter the surface chemistry and textural structure [101]. This

Preferential enrichment and extraction of laser-synthesized nanoparticles in organic phases

• Theo Fromme,
• Maximilian L. Spiekermann,
• Florian Lehmann,
• Stephan Barcikowski,
• Thomas Seidensticker and
• Sven Reichenberger

Beilstein J. Nanotechnol. 2025, 16, 254–263, doi:10.3762/bjnano.16.20

• properties and surface chemistry of the gained colloids. The use of organic solvents as liquid may result in reactive LAL processes [1][10] that cause elements from the solvent molecules (and solutes) to be part of the final nanoparticle’s composition. The solvent decomposition induced by laser-based

• their surface chemistry will affect the particles’ wettability or hydrophobicity, the phase transfer between two liquid phases with different polarities has not been investigated previously. We approached this issue by using thermomorphic multiphase systems (TMSs), switchable mixtures that can change

• rates also lead to different reactivity with the cooling solvent molecules that set the final surface chemistry of the particles and, thereby, affect their phase preference. Since the standard electrochemical reduction potential of Cu and Fe is close to 0 V, the different polarities of propylene

Recent advances in photothermal nanomaterials for ophthalmic applications

• Jiayuan Zhuang,
• Linhui Jia,
• Chenghao Li,
• Rui Yang,
• Jiapeng Wang,
• Wen-an Wang,
• Heng Zhou and
• Xiangxia Luo

Beilstein J. Nanotechnol. 2025, 16, 195–215, doi:10.3762/bjnano.16.16

• therapeutic effects in humans [213]. The safety profile of photothermal nanomaterials is influenced by various factors, including their morphology, structure, concentration, photothermal stability, mechanical strength, and surface chemistry [214]. Enhancements in biocompatibility and stability can be achieved

Nanocarriers and macrophage interaction: from a potential hurdle to an alternative therapeutic strategy

• Naths Grazia Sukubo,
• Paolo Bigini and
• Annalisa Morelli

Beilstein J. Nanotechnol. 2025, 16, 97–118, doi:10.3762/bjnano.16.10

• influence PC formation and NC clearance, including NP size, surface charge, hydrophobicity, surface chemistry, and the encountered biological fluid [37][38][39]. NPs larger than 200 nm in size tend to accumulate in the liver and spleen, while those with a diameter of less than 10 nm are rapidly eliminated

Instance maps as an organising concept for complex experimental workflows as demonstrated for (nano)material safety research

• Benjamin Punz,
• Maja Brajnik,
• Joh Dokler,
• Jaleesia D. Amos,
• Litty Johnson,
• Katie Reilly,
• Anastasios G. Papadiamantis,
• Amaia Green Etxabe,
• Lee Walker,
• Diego S. T. Martinez,
• Steffi Friedrichs,
• Klaus M. Weltring,
• Nazende Günday-Türeli,
• Claus Svendsen,
• Christine Ogilvie Hendren,
• Mark R. Wiesner,
• Martin Himly,
• Iseult Lynch and
• Thomas E. Exner

Beilstein J. Nanotechnol. 2025, 16, 57–77, doi:10.3762/bjnano.16.7

• properties can be tailored by changing their size, shape, surface chemistry, and functionality, have led to the designation of nanomaterials as a key enabling technology and to their subsequent inclusion in the broader categorisation of advanced materials [1][2]. Applications of nanomaterials derive in many

Bioinspired nanofilament coatings for scale reduction on steel

• Siad Dahir Ali,
• Mette Heidemann Rasmussen,
• Jacopo Catalano,
• Christian Husum Frederiksen and
• Tobias Weidner

Beilstein J. Nanotechnol. 2025, 16, 25–34, doi:10.3762/bjnano.16.3

• polymerization of a polysiloxane on the material surface [18]. The polysiloxane methyl groups lower the surface energy and render the surface hydrophobic. Clearly, the surface chemistry of steel surfaces is very different from the previously used materials such as glass [11][12][13][18], polymers [10][11][12

Liver-targeting iron oxide nanoparticles and their complexes with plant extracts for biocompatibility

• Shushanik A. Kazaryan,
• Seda A. Oganian,
• Gayane S. Vardanyan,
• Anatolie S. Sidorenko and
• Ashkhen A. Hovhannisyan

Beilstein J. Nanotechnol. 2024, 15, 1593–1602, doi:10.3762/bjnano.15.125

• and toxicity effects; as of May 2024, the website clinicaltrials.gov listed data on the development of 51 clinical protocols involving iron oxides NPs [25][26][27]. Surface chemistry and delivery route of MNPs affect their biodistribution patterns and circulation time in the body [28]. It is known

Facile synthesis of size-tunable L-carnosine-capped silver nanoparticles and their role in metal ion sensing and catalytic degradation of p-nitrophenol

• Akash Kumar,
• Ridhima Chadha,
• Abhishek Das,
• Nandita Maiti and
• Rayavarapu Raja Gopal

Beilstein J. Nanotechnol. 2024, 15, 1576–1592, doi:10.3762/bjnano.15.124

• through surface chemistry and other parameters such as size and shape [13]. Kästner and Thünemann described the catalytic degradation of P-NP using silver nanoparticles with the activity depending on the capping agents [14]. To design a dual-functional system for environmental applications, a potential

Polymer lipid hybrid nanoparticles for phytochemical delivery: challenges, progress, and future prospects

• Iqra Rahat,
• Pooja Yadav,
• Aditi Singhal,
• Mohammad Fareed,
• Jaganathan Raja Purushothaman,
• Mohammed Aslam,
• Raju Balaji,
• Sonali Patil-Shinde and
• Md. Rizwanullah

Beilstein J. Nanotechnol. 2024, 15, 1473–1497, doi:10.3762/bjnano.15.118

• ., erythrocytes) to develop membrane-camouflaged PLHNPs. These hybrid nanocarriers are also called biomimetic hybrid nanocarriers because their surface chemistry mimics natural cell membranes [57]. The PLHNPs are coated with cell membranes via the extrusion technique. The coating of PLHNPs with red blood cells