4 article(s) from Chebanov, Valentyn A
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- Published 08 Mar 2021
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Figure 1: Benzodiazepine-based azolo-containing drugs.
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Figure 2: Novel potential 1,2,3-triazolobenziadiazepine drugs.
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Scheme 1: Examples of synthesis of 1,2,3-triazolobenzodiazepines via tandem approach Ugi reaction/IAAC. Reage...
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Scheme 2: Azide precursor synthesis.
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Scheme 3: Synthesis of Ugi products 6, their structures and yields.
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Figure 3: Code legend for Ugi products 6 and molecular structure (X-ray analysis) of compound 6aaa.
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Scheme 4: Cyclization of Ugi-product 6aab with terminal alkyne fragment.
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Figure 4: 1H NMR spectra of the reactant and the product of IAAC.
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Figure 5: Molecular structure of compound 7aaa (X-ray analysis) and comparison of 1H NMR spectra of compounds ...
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Scheme 5: The substrate scope of intermolecular cycloaddition.
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- Full Research Paper
- Published 27 Feb 2020
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Scheme 1: Synthesis of tetrahydroazolopyrimidine derivatives.
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Scheme 2: Various multicomponent reactions involving pyruvic acids (pyruvates) and different α-aminoazoles.
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Scheme 3: Synthesis of 4-arylamino-substituted tetrahydroquinolines.
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Scheme 4: Ultrasound-assisted multicomponent reactions of 3-amino-1,2,4-triazole or 5-amino-1H-pyrazole-4-car...
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Scheme 5: Synthesis of 3-cyano-7-(4-methoxyphenyl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-5-carboxylic acid (7)....
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Scheme 6: Proposed reaction mechanism.
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Figure 1: Alternative structures A and B for the tetrahydroazolopyrimidines 4.
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Figure 2: Molecular structure of ethyl 5-(4-bromophenyl)-3-cyano-7-((4-cyano-1H-pyrazol-5-yl)amino)-4,5,6,7-t...
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Figure 3: Chains of 4g molecules in the crystal phase.
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- Full Research Paper
- Published 08 Oct 2019
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Scheme 1: Three synthetic approaches to dihydrotetrazolo[1,5-a]pyrimidines.
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Scheme 2: Three-component reaction of 1, 7a,b and 8a–d in water.
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Figure 1: Molecular structure of 9a according to X-ray data. Displacement ellipsoids are shown at the 50% pro...
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Scheme 3: Three-component reaction of 5-aminotetrazole (1) with formaldehyde (7a) and acetylacetone (10).
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Scheme 4: a) Three-component reaction of 5-aminotetrazole (1) with acetaldehyde (7b) and ethyl 4,4,4-trifluor...
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- Published 12 Jun 2019
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Scheme 1: An overview of heterocyclic acids used in the Ugi reaction.
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Scheme 2: Synthesis of pyrazolopyridine carboxylic acids 4 [45] and 7 [45] in Doebner-type reaction.
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Figure 1: Molecular structure of N-(2-(tert-butylamino)-1-(4-chlorophenyl)-2-oxoethyl)-6-(4-methoxyphenyl)-3-...
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