5 article(s) from Tarui, Atsushi
- Full Research Paper
- Published 11 Jan 2021
-
PDF -
Album-
![]()
Graphical Abstract
-
![]()
Figure 1: Medical compounds having a difluoromethyl group.
-
![]()
Scheme 1: Methods for the synthesis of ethers containing fluorine substituents.
-
![]()
Scheme 2: The previous work reported by Yagupol’skii et al.
-
![]()
Scheme 3: Intramolecular 1,4-addition of 2o.
-
![]()
Scheme 4: Proposed reaction mechanism.
-
-
Supp. Info
- Full Research Paper
- Published 22 Jun 2020
-
PDF -
Album-
![]()
Graphical Abstract
-
![]()
Scheme 1: Selective fluorination of isoxazoles and one-pot synthesis of 4-fluoroisoxazoles.
-
![]()
Scheme 2: One-pot reaction for the synthesis of 3,5-disubstituted 4-fluoroisoxazoles 3. aIsolated yield. bIso...
-
![]()
Figure 1: UV–vis and fluorescence (FL) spectra of compounds 3b and 3c.
-
![]()
Scheme 3: Synthesis of BKIs 6 either from 1,3-diketones 1 or from isoxazoles 2.
-
![]()
Scheme 4: Synthesis of enaminoketones 5 and 8 and their conversion to BKIs (yields refer to isolated yields; a...
-
![]()
Scheme 5: Attempted selective fluorination of BKI 6b.
-
![]()
Scheme 6: Ring-opening reaction of 4-fluoroisoxazoles 3 and their conversion into F-BKIs 9 (yields refer to i...
-
![]()
Figure 2: Photochemical properties comparisons of BKIs and F-BKIs. (a–c) BKI 6b: photograph (a), UV–vis (b), ...
-
-
Supp. Info
- Full Research Paper
- Published 14 Dec 2017
-
PDF -
Album-
![]()
Graphical Abstract
-
![]()
Figure 1: (a) UV–vis absorption and (b) fluorescence spectra of 1–4 in THF.
-
![]()
Figure 2: Fluorescence spectra of 1 and 3 in H2O:DMSO (9:1).
-
![]()
Scheme 1: Use of 1 as fluorogenic probe for DPP-4 activity.
-
![]()
Scheme 2: Synthesis of fluorogenic probe H-Gly-Pro-1.
-
![]()
Figure 3: Fluorescence spectra of 1 and H-Gly-Pro-1. Measurement conditions: 1.0 × 10−5 M in H2O:DMSO (9:1), ...
-
![]()
Figure 4: Fluorescence intensity changes of H-Gly-Pro-1 on addition of DPP-4.
-
- Full Research Paper
- Published 27 Jul 2016
-
PDF -
Album-
![]()
Graphical Abstract
-
![]()
Scheme 1: The synthesis of syn-β-lactams using a reductive Mannich-type reaction.
-
![]()
Scheme 2: Previous results using β-substituted α,β-unsaturated esters.
-
![]()
Scheme 3: A new synthetic route for ezetimibe.
-
![]()
Figure 1: Plausible mechanism for the Rh-catalyzed reductive Mannich-type reaction.
-
![]()
Scheme 4: Effect of the Lewis acid addition.
-
![]()
Figure 2: Reaction of 2k and 1A and the configuration of Int A.
-
![]()
Scheme 5: Transition-state model without Lewis acid.
-
![]()
Scheme 6: Transition-state model with Lewis acid.
-
-
Supp. Info
- Full Research Paper
- Published 11 Nov 2013
-
PDF -
Album-
![]()
Graphical Abstract
-
![]()
Scheme 1: Experiments to elucidate the reaction mechanism.
-
![]()
Scheme 2: The proposed reaction mechanism.
-
-
Supp. Info
