Reactive intermediates part I: radicals

  1. editorImage
  1. Editor: Prof. Tehshik P. Yoon
    University of Wisconsin-Madison

Open-shelled, odd-electron organic molecules were once believed to be so unstable that they could not exist or that their reactions would always be uncontrolled. However, beginning with Gomberg’s description of the chemistry of triphenylmethyl radical, a wide range of important reactions have been shown to involve radical intermediates. These span examples from classical photochemically and thermolytically initiated organoradical chemistry, transition metal chemistry, electrochemistry, biological chemistry, and modern photoredox chemistry. Indeed, organic radical chemistry is among the most active research areas in contemporary organic chemistry. This thematic issue highlights the current progress in this field and provide a cross-section of the diverse research questions that motivating the growing activity in radical chemistry.

Photocatalyic Appel reaction enabled by copper-based complexes in continuous flow

  1. Clémentine Minozzi,
  2. Jean-Christophe Grenier-Petel,
  3. Shawn Parisien-Collette and
  4. Shawn K. Collins
  • Letter
  • Published 30 Oct 2018

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  • Supp. Info

Beilstein J. Org. Chem. 2018, 14, 2730–2736, doi:10.3762/bjoc.14.251

  • Full Research Paper
  • Published 23 Nov 2018

Beilstein J. Org. Chem. 2018, 14, 2916–2922, doi:10.3762/bjoc.14.270

Degenerative xanthate transfer to olefins under visible-light photocatalysis

  1. Atsushi Kaga,
  2. Xiangyang Wu,
  3. Joel Yi Jie Lim,
  4. Hirohito Hayashi,
  5. Yunpeng Lu,
  6. Edwin K. L. Yeow and
  7. Shunsuke Chiba
  • Full Research Paper
  • Published 13 Dec 2018

Beilstein J. Org. Chem. 2018, 14, 3047–3058, doi:10.3762/bjoc.14.283

Tandem copper and photoredox catalysis in photocatalytic alkene difunctionalization reactions

  1. Nicholas L. Reed,
  2. Madeline I. Herman,
  3. Vladimir P. Miltchev and
  4. Tehshik P. Yoon
  • Letter
  • Published 05 Feb 2019

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  • Supp. Info

Beilstein J. Org. Chem. 2019, 15, 351–356, doi:10.3762/bjoc.15.30

A diastereoselective approach to axially chiral biaryls via electrochemically enabled cyclization cascade

  1. Hong Yan,
  2. Zhong-Yi Mao,
  3. Zhong-Wei Hou,
  4. Jinshuai Song and
  5. Hai-Chao Xu
  • Letter
  • Published 28 Mar 2019

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  • Supp. Info

Beilstein J. Org. Chem. 2019, 15, 795–800, doi:10.3762/bjoc.15.76

Photochemical generation of the 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) radical from caged nitroxides by near-infrared two-photon irradiation and its cytocidal effect on lung cancer cells

  1. Ayato Yamada,
  2. Manabu Abe,
  3. Yoshinobu Nishimura,
  4. Shoji Ishizaka,
  5. Masashi Namba,
  6. Taku Nakashima,
  7. Kiyofumi Shimoji and
  8. Noboru Hattori
  • Full Research Paper
  • Published 10 Apr 2019

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  • Supp. Info

Beilstein J. Org. Chem. 2019, 15, 863–873, doi:10.3762/bjoc.15.84

Vicinal difunctionalization of alkenes by four-component radical cascade reaction of xanthogenates, alkenes, CO, and sulfonyl oxime ethers

  1. Shuhei Sumino,
  2. Takahide Fukuyama,
  3. Mika Sasano,
  4. Ilhyong Ryu,
  5. Antoine Jacquet,
  6. Frédéric Robert and
  7. Yannick Landais
  • Letter
  • Published 31 Jul 2019

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  • Supp. Info

Beilstein J. Org. Chem. 2019, 15, 1822–1828, doi:10.3762/bjoc.15.176

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