Multifrequency AFM integrating PeakForce tapping and higher eigenmodes for heterogeneous surface characterization

• Yanping Wei,
• Jiafeng Shen,
• Yirong Yao,
• Xuke Li,
• Ming Li and
• Peiling Ke

Beilstein J. Nanotechnol. 2025, 16, 2077–2085, doi:10.3762/bjnano.16.142

• -sample-related contribution, a 3×3 median filter was applied, and all subsequent quantitative analysis was performed on the processed data. Results and Discussion Vibration control strategy in PFT-based multifrequency AFM mode In standard PFT mode, acquiring high-frequency force curves (typically 0.5–2

Mechanical property measurements enabled by short-term Fourier-transform of atomic force microscopy thermal deflection analysis

• Thomas Mathias,
• Roland Bennewitz and
• Philip Egberts

Beilstein J. Nanotechnol. 2025, 16, 1952–1962, doi:10.3762/bjnano.16.136

• resonance data with contact stiffness, or other mechanical property assessments, very difficult. Thus, our findings show that, while high-fidelity data of the changing oscillatory behavior of AFM cantilevers can be obtained with high sampling rates and subsequent STFT analysis, quantitative analysis is not

PEGylated lipids in lipid nanoparticle delivery dynamics and therapeutic innovation

• Peiyang Gao

Beilstein J. Nanotechnol. 2025, 16, 1914–1930, doi:10.3762/bjnano.16.133

• azidoacetyl-modified A PD-L1-binding ᴅ-peptide before introducing to LNP formulation. The synthesized DSPE-PEG2K-Pep conjugate was incorporated into LNPs at 0.3 mol % for optimal coating saturation. Quantitative analysis showed Pep-LNPs achieved over 85% of surface coverage by DSPE-PEG2K-Pep conjugate without

Ambient pressure XPS at MAX IV

• Mattia Scardamaglia,
• Ulrike Küst,
• Alexander Klyushin,
• Rosemary Jones,
• Jan Knudsen,
• Robert Temperton,
• Andrey Shavorskiy and
• Esko Kokkonen

Beilstein J. Nanotechnol. 2025, 16, 1677–1694, doi:10.3762/bjnano.16.118

Mechanical stability of individual bacterial cells under different osmotic pressure conditions: a nanoindentation study of Pseudomonas aeruginosa

• Lizeth García-Torres,
• Idania De Alba Montero,
• Eleazar Samuel Kolosovas-Machuca,
• Facundo Ruiz,
• Sumati Bhatia,
• Jose Luis Cuellar Camacho and
• Jaime Ruiz-García

Beilstein J. Nanotechnol. 2025, 16, 1171–1183, doi:10.3762/bjnano.16.86

• must be clearly distinguished from a rigid substrate used as background. In this case, the thin layer of PLL (1–2 nm) on mica is expected to provide such background. Regions especially crowded with bacteria were intentionally avoided when applying FV. The capacity of AFM as a quantitative analysis tool

Transfer function of an asymmetric superconducting Gauss neuron

• Fedor A. Razorenov,
• Aleksander S. Ionin,
• Nikita S. Shuravin,
• Liubov N. Karelina,
• Mikhail S. Sidel’nikov,
• Sergey V. Egorov and
• Vitaly V. Bol’ginov

Beilstein J. Nanotechnol. 2025, 16, 1160–1170, doi:10.3762/bjnano.16.85

• [17][18], we get t = 0.2. Calculations based on Equation 52 give a similar shape of the TF (compared to Figure 6a) at ϕb = 0.3π. Thus, experimental results correspond to the expected ones, and a quantitative analysis shall be the subject of our subsequent publications. The problem with cross-talk

Towards a quantitative theory for transmission X-ray microscopy

• James G. McNally,
• Christoph Pratsch,
• Stephan Werner,
• Stefan Rehbein,
• Andrew Gibbs,
• Jihao Wang,
• Thomas Lunkenbein,
• Peter Guttmann and
• Gerd Schneider

Beilstein J. Nanotechnol. 2025, 16, 1113–1128, doi:10.3762/bjnano.16.82

• Transmission X-ray microscopes (TXMs) are now increasingly used for quantitative analysis of samples, most notably in the spectral analysis of materials. Validating such measurements requires quantitatively accurate models for these microscopes, but current TXM models have only been tested qualitatively. Here

• for TXMs but also identifies two areas for future work that will improve the quantitative analysis of TXM data. First, our finding that both β and δ play a role in TXM imaging highlights the need to investigate to what extent δ influences quantitative analyses such as those in spectromicroscopy that

• (Supporting Information File 1, Section S12) and the non-tilted condenser model was much easier to compute. To enable a more precise quantitative analysis, we first extensively characterized the gold nanospheres by both scanning and transmission electron microscopy (SEM and TEM, Supporting Information File 1

Single-layer graphene oxide film grown on α-Al₂O₃(0001) for use as an adsorbent

• Shiro Entani,
• Mitsunori Honda,
• Masaru Takizawa and
• Makoto Kohda

Beilstein J. Nanotechnol. 2025, 16, 1082–1087, doi:10.3762/bjnano.16.79

• and/or alkalinity for the efficient Cs adsorption by SLGO. With regard to the quantitative analysis, it is also noted that SLGO shows high adsorption capacity of Cs. That is, the weight adsorption capacity in the CsCl solution with pH 7 is estimated to be 650–850 mg Cs per 1 g SLGO, which corresponds

Time-resolved probing of laser-induced nanostructuring processes in liquids

• Maximilian Spellauge,
• David Redka,
• Mianzhen Mo,
• Changyong Song,
• Heinz Paul Huber and
• Anton Plech

Beilstein J. Nanotechnol. 2025, 16, 968–1002, doi:10.3762/bjnano.16.74

• transient absorption, first through plasmon dampening and with increasing bubble size through the increase in scattering once the bubble reaches some 100 nm in diameter. A quantitative analysis of the change of the TAS signal as compared to Mie calculations can in some cases even reproduce the bubble

Colloidal few layered graphene–tannic acid preserves the biocompatibility of periodontal ligament cells

• Teissir Ben Ammar,
• Naji Kharouf,
• Dominique Vautier,
• Housseinou Ba,
• Nivedita Sudheer,
• Philippe Lavalle and
• Vincent Ball

Beilstein J. Nanotechnol. 2025, 16, 664–677, doi:10.3762/bjnano.16.51

• more in-depth its layered structure, consisting of approximately four layers. Quantitative analysis of SEM and TEM images enabled the determination of the FLG–TA sheets’ average lateral size distribution, presented in Figure 1F, indicating an average lateral size of approximately 2 µm. Note that the

Performance optimization of a microwave-coupled plasma-based ultralow-energy ECR ion source for silicon nanostructuring

• Joy Mukherjee,
• Safiul Alam Mollick,
• Tanmoy Basu and
• Tapobrata Som

Beilstein J. Nanotechnol. 2025, 16, 484–494, doi:10.3762/bjnano.16.37

• ions at different incidence angles and for various irradiation times is investigated using AFM in tapping mode. Si cantilevers with tip radii of 10 nm were employed, with scan rate of 1 µm/s and a fixed scan size of 5 µm × 5 µm. Quantitative analysis of the surface topography was conducted using WSxM

Quantification of lead through rod-shaped silver-doped zinc oxide nanoparticles using an electrochemical approach

• Ravinder Lamba,
• Gaurav Bhanjana,
• Neeraj Dilbaghi,
• Vivek Gupta and
• Sandeep Kumar

Beilstein J. Nanotechnol. 2025, 16, 422–434, doi:10.3762/bjnano.16.33

• of the modified electrode at a varying concentration of lead in (a) canal water, (b) groundwater, (c) water obtained after reverse osmosis (RO) and (d), supply drinking water. Quantitative analysis of lead concentrations in real samples artificially contaminated with lead. Comparison between the

Engineered PEG–PCL nanoparticles enable sensitive and selective detection of sodium dodecyl sulfate: a qualitative and quantitative analysis

• Soni Prajapati and
• Ranjana Singh

Beilstein J. Nanotechnol. 2025, 16, 385–396, doi:10.3762/bjnano.16.29

• Scientific, USA). Interference and quantitative analysis The specificity of SDS detection was evaluated through interference studies in the presence of various metal ions and surfactants. Three experimental groups were established: (1) a control group without added surfactants or metals, (2) a comprehensive

Tailoring of physical properties of RF-sputtered ZnTe films: role of substrate temperature

• Kafi Devi,
• Usha Rani,
• Arun Kumar,
• Divya Gupta and
• Sanjeev Aggarwal

Beilstein J. Nanotechnol. 2025, 16, 333–348, doi:10.3762/bjnano.16.25

• of the substrate. A significant change in particle size along with a change in agglomerated particle density occurs with increasing substrate temperature. The surface is free from pinholes and voids, and clusters of particles can be seen. Quantitative analysis of the surface composition was carried

Clays enhanced with niobium: potential in wastewater treatment and reuse as pigment with antibacterial activity

• Silvia Jaerger,
• Patricia Appelt,
• Mario Antônio Alves da Cunha,
• Fabián Ccahuana Ayma,
• Ricardo Schneider,
• Carla Bittencourt and
• Fauze Jacó Anaissi

Beilstein J. Nanotechnol. 2025, 16, 141–154, doi:10.3762/bjnano.16.13

• exchanged with sodium counter ions. In recent years, laser-induced breakdown spectroscopy, an optical emission spectroscopic technique, has emerged as a rapid qualitative and quantitative analysis [19]. This spectroscopic technique can be explained by the short-duration, high-intensity pulsed laser being

Bioinspired nanofilament coatings for scale reduction on steel

• Siad Dahir Ali,
• Mette Heidemann Rasmussen,
• Jacopo Catalano,
• Christian Husum Frederiksen and
• Tobias Weidner

Beilstein J. Nanotechnol. 2025, 16, 25–34, doi:10.3762/bjnano.16.3

• quantitative analysis of the extent of scaling, the samples were weighed before and after exposure to the scaling experiment. The results are summarized in Figure 6D. The gravimetric analysis shows that without the coating, the samples gained 16.3 ± 2.7 mg of calcium carbonate, while SNF-coated samples gained

Mechanistic insights into endosomal escape by sodium oleate-modified liposomes

• Ebrahim Sadaqa,
• Satrialdi,
• Fransiska Kurniawan and
• Diky Mudhakir

Beilstein J. Nanotechnol. 2024, 15, 1667–1685, doi:10.3762/bjnano.15.131

• nuclei. Confocal microscopy (Olympus FV-1200 Tokyo, Japan) was used to capture images of cellular uptake, and the mean fluorescence intensity was quantified using Fiji-ImageJ software for semi-quantitative analysis. Evaluation of endosomal escape efficiency through subcellular colocalization analysis In

New design of operational MEMS bridges for measurements of properties of FEBID-based nanostructures

• Bartosz Pruchnik,
• Krzysztof Kwoka,
• Ewelina Gacka,
• Dominik Badura,
• Piotr Kunicki,
• Andrzej Sierakowski,
• Paweł Janus,
• Tomasz Piasecki and
• Teodor Gotszalk

Beilstein J. Nanotechnol. 2024, 15, 1273–1282, doi:10.3762/bjnano.15.103

• is not well suited for quantitative analysis of the FIB strain process. Instead, for a comprehensive analysis of FIB-induced strain, the analysis should be performed on a model MEMS device, similar to our previous work [17] or the method developed by the authors of [55], who analysed residual

Intermixing of MoS₂ and WS₂ photocatalysts toward methylene blue photodegradation

• Maryam Al Qaydi,
• Nitul S. Rajput,
• Michael Lejeune,
• Abdellatif Bouchalkha,
• Mimoun El Marssi,
• Steevy Cordette,
• Chaouki Kasmi and
• Mustapha Jouiad

Beilstein J. Nanotechnol. 2024, 15, 817–829, doi:10.3762/bjnano.15.68

• ascribed to W–O bonding [31]. This suggests the presence of minor oxidation of the flakes. Further quantitative analysis of XPS data indicates the following atomic compositions: Mo: 34.68%, S: 65.32%, W: 33.98%, S: 66.02%, and Mo: 14.06%, W: 23.70, S: 62.24%, respectively for MoS2, WS2, and MoS2/WS2

Electron-induced deposition using Fe(CO)₄MA and Fe(CO)₅ – effect of MA ligand and process conditions

• Hannah Boeckers,
• Atul Chaudhary,
• Petra Martinović,
• Amy V. Walker,
• Lisa McElwee-White and
• Petra Swiderek

Beilstein J. Nanotechnol. 2024, 15, 500–516, doi:10.3762/bjnano.15.45

• ) values [55]. The results of such analyses for all deposition experiments presented herein are summarized in Supporting Information File 1 (Tables S1 and S2). However, this approach to a quantitative analysis of AES data is only appropriate for overlayers with homogeneous thickness and distribution of the

Potential of a deep eutectic solvent in silver nanoparticle fabrication for antibiotic residue detection

• Le Hong Tho,
• Bui Xuan Khuyen,
• Ngoc Xuan Dat Mai and
• Nhu Hoa Thi Tran

Beilstein J. Nanotechnol. 2024, 15, 426–434, doi:10.3762/bjnano.15.38

• Ag NPs-DES substrate is sensitive and can be used for quantitative analysis of NFT following the two linear fitting equations: For further investigations on the SERS performance of the Ag NPs-DES thin film, NFT was again selected to test the stability. In practice, a stable SERS substrate is not only

unDrift: A versatile software for fast offline SPM image drift correction

• Tobias Dickbreder,
• Franziska Sabath,
• Lukas Höltkemeier,
• Ralf Bechstein and
• Angelika Kühnle

Beilstein J. Nanotechnol. 2023, 14, 1225–1237, doi:10.3762/bjnano.14.101

• , algorithm III offers the possibility to easily assess and quantify the effect of non-linear drift in the drift-corrected SPM data, which is not available from the other algorithms. Lateral calibration In addition to the correction of drift, it is crucial for a quantitative analysis of SPM data that the

Hierarchically patterned polyurethane microgrooves featuring nanopillars or nanoholes for neurite elongation and alignment

• Lester Uy Vinzons,
• Guo-Chung Dong and
• Shu-Ping Lin

Beilstein J. Nanotechnol. 2023, 14, 1157–1168, doi:10.3762/bjnano.14.96

• –groove substrate. Quantitative analysis of neurite directionality on the grooved substrates reveals an improvement in neurite alignment on the nanopatterned grooves, as can be seen in the increase in the amount of neurites aligned within 15° of the grooves, considering all neurite branches (Figure 4G and

Curcumin-loaded albumin submicron particles with potential as a cancer therapy: an in vitro study

• Nittiya Suwannasom,
• Netsai Sriaksorn,
• Chutamas Thepmalee,
• Krissana Khoothiam,
• Ausanai Prapan,
• Hans Bäumler and
• Chonthida Thephinlap

Beilstein J. Nanotechnol. 2023, 14, 1127–1140, doi:10.3762/bjnano.14.93

• cellular uptake of HSA-MPs and CUR-HSA-MPs. The intrinsic fluorescence of both particle types excited at 488 nm allowed for their visualization, as the fluorescence properties were preserved upon encapsulation (Figure 2E). Quantitative analysis of cellular uptake, performed through flow cytometry, revealed

Nanoarchitectonics of photothermal materials to enhance the sensitivity of lateral flow assays

• Elangovan Sarathkumar,
• Rajasekharan S. Anjana and
• Ramapurath S. Jayasree

Beilstein J. Nanotechnol. 2023, 14, 988–1003, doi:10.3762/bjnano.14.82

• nanoparticles through the nitrocellulose membrane pores and led to nonspecific binding of analytes and unwanted background signals (Figure 7B). In comparison to the visual method, the photothermal signal amplification technique allowed for the quantitative analysis of analytes with a sensitivity increased by a