Magnetic properties of biofunctionalized iron oxide nanoparticles as magnetic resonance imaging contrast agents

• Natalia E. Gervits,
• Andrey A. Gippius,
• Alexey V. Tkachev,
• Evgeniy I. Demikhov,
• Sergey S. Starchikov,
• Igor S. Lyubutin,
• Alexander L. Vasiliev,
• Vladimir P. Chekhonin,
• Maxim A. Abakumov,
• Alevtina S. Semkina and
• Alexander G. Mazhuga

Beilstein J. Nanotechnol. 2019, 10, 1964–1972, doi:10.3762/bjnano.10.193

• Background: One of the future applications of magnetic nanoparticles is the development of new iron-oxide-based magnetic resonance imaging (MRI) negative contrast agents, which are intended to improve the results of diagnostics and complement existing Gd-based contrast media. Results: Iron oxide

Growth dynamics and light scattering of gold nanoparticles in situ synthesized at high concentration in thin polymer films

• Corentin Guyot,
• Philippe Vandestrick,
• Ingrid Marenne,
• Olivier Deparis and
• Michel Voué

Beilstein J. Nanotechnol. 2019, 10, 1768–1777, doi:10.3762/bjnano.10.172

• solar infrared radiation [3][4], in random lasers [5][6], in non-linear optical applications [7][8][9] and in sensors or bio-medical diagnostics [10][11][12]. More recently, nanocomposites containing AuNPs received even more attention due to their saturable absorption. Indeed, plasmonic nanocomposites

Effects of gold and PCL- or PLLA-coated silica nanoparticles on brain endothelial cells and the blood–brain barrier

• Aniela Bittner,
• Angélique D. Ducray,
• Hans Rudolf Widmer,
• Michael H. Stoffel and
• Meike Mevissen

Beilstein J. Nanotechnol. 2019, 10, 941–954, doi:10.3762/bjnano.10.95

• , and has gained further importance over the past few decades [1]. This technology also offers promising possibilities for medical applications such as tumor diagnostics and therapy, as drug carriers or in biodegradable implants, e.g., in laser tissue soldering (LTS) [2]. LTS provides a promising

Features and advantages of flexible silicon nanowires for SERS applications

• Hrvoje Gebavi,
• Vlatko Gašparić,
• Dubravko Risović,
• Nikola Baran,
• Paweł Henryk Albrycht and
• Mile Ivanda

Beilstein J. Nanotechnol. 2019, 10, 725–734, doi:10.3762/bjnano.10.72

• SAFU, project 263 KK.01.1.1.01.0001., Croatian Science Foundation under the project (IP-2014-09-7046) and COST action BM1401 - Raman-based applications for clinical diagnostics (Raman4Clinics). The authors would like to thank Silmeco, SERSitive and AtoID companies for SERS substrates providing.

A carrier velocity model for electrical detection of gas molecules

• Ali Hosseingholi Pourasl,
• Sharifah Hafizah Syed Ariffin,
• Mohammad Taghi Ahmadi,
• Razali Ismail and
• Niayesh Gharaei

Beilstein J. Nanotechnol. 2019, 10, 644–653, doi:10.3762/bjnano.10.64

• . Graphene nanoribbons (GNRs) which have exceptional electrical, physical, and chemical properties can fulfil all of these requirements. The detection of gas molecules using gas sensors, particularly in medical diagnostics and safety applications, is receiving particularly high demand. GNRs exhibit

Surface plasmon resonance enhancement of photoluminescence intensity and bioimaging application of gold nanorod@CdSe/ZnS quantum dots

• Siyi Hu,
• Yu Ren,
• Yue Wang,
• Jinhua Li,
• Junle Qu,
• Liwei Liu,
• Hanbin Ma and
• Yuguo Tang

Beilstein J. Nanotechnol. 2019, 10, 22–31, doi:10.3762/bjnano.10.3

• Siyi Hu Yu Ren Yue Wang Jinhua Li Junle Qu Liwei Liu Hanbin Ma Yuguo Tang CAS Key Laboratory of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, P. R. China School of Science, Changchun University of Science and

Contactless photomagnetoelectric investigations of 2D semiconductors

• Marian Nowak,
• Marcin Jesionek,
• Barbara Solecka,
• Piotr Szperlich,
• Piotr Duka and
• Anna Starczewska

Beilstein J. Nanotechnol. 2018, 9, 2741–2749, doi:10.3762/bjnano.9.256

• illumination was determined using a Rigol Technologies DS1202CA oscilloscope. The spatial distribution of illumination (Figure 4b,c) was controlled using a beam diagnostics digital CCD camera LaserCam-HR II and BeamView version 4.8.1 software (Coherent). From this measurement, an effective diameter of 52 μm

Size-selected Fe₃O₄–Au hybrid nanoparticles for improved magnetism-based theranostics

• Maria V. Efremova,
• Yulia A. Nalench,
• Eirini Myrovali,
• Anastasiia S. Garanina,
• Ivan S. Grebennikov,
• Polina K. Gifer,
• Maxim A. Abakumov,
• Marina Spasova,
• Makis Angelakeris,
• Alexander G. Savchenko,
• Michael Farle,
• Natalia L. Klyachko,
• Alexander G. Majouga and
• Ulf Wiedwald

Beilstein J. Nanotechnol. 2018, 9, 2684–2699, doi:10.3762/bjnano.9.251

• hyperthermia; magnetic resonance imaging; nanomagnetism; theranostics; Introduction Biocompatible magnetite nanoparticles (NPs) are anticipated to provide new noninvasive therapies and early diagnostics for previously incurable diseases using a single, so-called “theranostics” platform [1][2][3]. The magnetic

Non-agglomerated silicon–organic nanoparticles and their nanocomplexes with oligonucleotides: synthesis and properties

• Asya S. Levina,
• Marina N. Repkova,
• Nadezhda V. Shikina,
• Zinfer R. Ismagilov,
• Svetlana A. Yashnik,
• Dmitrii V. Semenov,
• Yulia I. Savinovskaya,
• Natalia A. Mazurkova,
• Inna A. Pyshnaya and
• Valentina F. Zarytova

Beilstein J. Nanotechnol. 2018, 9, 2516–2525, doi:10.3762/bjnano.9.234

• series of works describes the synthesis of amino-containing silicon nanoparticles, so-called ORMOSIL, and their use for diagnostics and therapy [15][18]. Most often, these methods lead to the formation of nanoparticles with a diameter of 20–100 nm. Silica is particularly attractive as a functional

Optimization of the optical coupling in nanowire-based integrated photonic platforms by FDTD simulation

• Nan Guan,
• Andrey Babichev,
• Martin Foldyna,
• Dmitry Denisov,
• François H. Julien and
• Maria Tchernycheva

Beilstein J. Nanotechnol. 2018, 9, 2248–2254, doi:10.3762/bjnano.9.209

• communication; Introduction Today, infrared (IR) photonic integrated circuits (PICs) represent a well-established technology with numerous applications in optical telecommunications [1][2][3][4]. However, for life science applications (biosensors, molecular diagnostics, food inspection, etc.) visible light

High-throughput synthesis of modified Fresnel zone plate arrays via ion beam lithography

• Kahraman Keskinbora,
• Umut Tunca Sanli,
• Margarita Baluktsian,
• Corinne Grévent,
• Markus Weigand and
• Gisela Schütz

Beilstein J. Nanotechnol. 2018, 9, 2049–2056, doi:10.3762/bjnano.9.194

• that relatively large areas can be decorated with nanostructured devices via IBL by using multipurpose SEM/FIB instruments with potential applications in FEL focusing, extreme UV and soft X-ray lithography and as wavefront sensing devices for beam diagnostics. Keywords: extreme ultraviolet (EUV

Synthesis of carbon nanowalls from a single-source metal-organic precursor

• André Giese,
• Sebastian Schipporeit,
• Volker Buck and
• Nicolas Wöhrl

Beilstein J. Nanotechnol. 2018, 9, 1895–1905, doi:10.3762/bjnano.9.181

• superhydrophilic properties, which has a significant effect on cell growth, making CNWs an interesting material for biotechnology (bio-sensors) and medical technology (implants, diagnostics) [13][17]. The growth of CNWs is often referred to as a three-stage process that was originally proposed by Kondo and co

Surface characterization of nanoparticles using near-field light scattering

• Eunsoo Yoo,
• Yizhong Liu,
• Chukwuazam A. Nwasike,
• Sebastian R. Freeman,
• Brian C. DiPaolo,
• Bernardo Cordovez and
• Amber L. Doiron

Beilstein J. Nanotechnol. 2018, 9, 1228–1238, doi:10.3762/bjnano.9.114

• . Acknowledgements Funding for this work was provided by the NIH (1R21EB017504-01) and the Analytics and Diagnostics Laboratory at Binghamton University. We would like to thank Abbey Weith for her assistance with nanophotonic force microscopy experiments and initial data gathering.

Review on nanoparticles and nanostructured materials: history, sources, toxicity and regulations

• Jaison Jeevanandam,
• Ahmed Barhoum,
• Yen S. Chan,
• Alain Dufresne and
• Michael K. Danquah

Beilstein J. Nanotechnol. 2018, 9, 1050–1074, doi:10.3762/bjnano.9.98

Nanoparticle delivery to metastatic breast cancer cells by nanoengineered mesenchymal stem cells

• Liga Saulite,
• Karlis Pleiko,
• Ineta Popena,
• Dominyka Dapkute,
• Ricardas Rotomskis and
• Una Riekstina

Beilstein J. Nanotechnol. 2018, 9, 321–332, doi:10.3762/bjnano.9.32

• ; mesenchymal stem cells; quantum dots; spheroids; 3D cell culture; Introduction The recent progress in the development of nanoscale agents opens up new perspectives for targeted drug delivery in cancer diagnostics, imaging and therapy. However, once administered into the body, nanoparticles (NPs) are rapidly

• origin, such as adipogenic, osteogenic and chondrogenic cells [6]. MSC-based therapies are being increasingly investigated for their promising potential in cancer diagnostics and treatment [5][7][8]. In vivo studies have demonstrated that MSCs can effectively deliver nanorattle-encapsulated doxorubicin

Advances in nanocarbon composite materials

• Sharali Malik,
• Arkady V. Krasheninnikov and
• Silvia Marchesan

Beilstein J. Nanotechnol. 2018, 9, 20–21, doi:10.3762/bjnano.9.3

• then expanded to the area of two-dimensional materials. This Thematic Series contains reviews and articles spanning diverse areas of research and highlights promising applications for energy transfer composites, coatings, biosensors, diagnostics, biomedicine and advanced nanocarbon materials. Many of

• newer areas of nanocarbon materials for use in biomedicine and diagnostics. Energy transfer materials are also well represented with articles and reviews covering aspects of engineering, thermo-mechanical properties, photovoltaics and Li-ion battery materials. Last but not least, we would like to thank

Carbon nano-onions as fluorescent on/off modulated nanoprobes for diagnostics

• Stefania Lettieri,
• Marta d’Amora,
• Adalberto Camisasca,
• Alberto Diaspro and
• Silvia Giordani

Beilstein J. Nanotechnol. 2017, 8, 1878–1888, doi:10.3762/bjnano.8.188

Optical techniques for cervical neoplasia detection

• Tatiana Novikova

Beilstein J. Nanotechnol. 2017, 8, 1844–1862, doi:10.3762/bjnano.8.186

• [10], the low-grade squamous intraepithelial lesion (LSIL) usually indicates mild dysplasia (CIN 1), high-grade squamous intraepithelial lesion (HSIL) refers to moderate and severe dysplasia (CIN 2–3). This classification system is used for reporting cervical cytological diagnostics and for choosing

• screening and diagnostics techniques. Typically it requires up to three visits to a medical professional and several weeks in total in order to obtain the diagnosis and treatment, if necessary [23]. The implementation of new optical techniques may bring an alternative to the Pap/HPV test for screening and

• an improvement of colposcopy for guiding the biopsy and diagnosis. The performance of new techniques is estimated in terms of accuracy, time and cost of diagnostics, combined with patient comfort, which is relevant to the rate of participation in screening programs. Currently several optical methods

Synthesis and functionalization of NaGdF₄:Yb,Er@NaGdF₄ core–shell nanoparticles for possible application as multimodal contrast agents

• Dovile Baziulyte-Paulaviciene,
• Vitalijus Karabanovas,
• Marius Stasys,
• Greta Jarockyte,
• Vilius Poderys,
• Simas Sakirzanovas and
• Ricardas Rotomskis

Beilstein J. Nanotechnol. 2017, 8, 1815–1824, doi:10.3762/bjnano.8.183

• biologically active molecules, UCNPs could be multifunctional in both therapy and diagnostics (theranostics) [9]. However, biomedical applications require ultrasmall multifunctional nanoparticles to be hydrophilic, biocompatible and have intense upconversion emission and efficient paramagnetic properties

Development of an advanced diagnostic concept for intestinal inflammation: molecular visualisation of nitric oxide in macrophages by functional poly(lactic-co-glycolic acid) microspheres

• Kathleen Lange,
• Christian Lautenschläger,
• Maria Wallert,
• Stefan Lorkowski,
• Andreas Stallmach and
• Alexander Schiller

Beilstein J. Nanotechnol. 2017, 8, 1637–1641, doi:10.3762/bjnano.8.163

• visualise these cells in NO-mediated intestinal inflammation in vivo by fluorescent particle-based diagnostics in a second step. Here, we used a NO-sensitive dye, namely NO550, as a model molecule to proof the concept of a particle-based diagnostic as part of an advanced diagnostic concept for detecting

Calcium fluoride based multifunctional nanoparticles for multimodal imaging

• Marion Straßer,
• Joachim H. X. Schrauth,
• Sofia Dembski,
• Daniel Haddad,
• Bernd Ahrens,
• Stefan Schweizer,
• Bastian Christ,
• Alevtina Cubukova,
• Marco Metzger,
• Heike Walles,
• Peter M. Jakob and
• Gerhard Sextl

Beilstein J. Nanotechnol. 2017, 8, 1484–1493, doi:10.3762/bjnano.8.148

• different imaging techniques, such as photoluminescence (PL) microscopy and magnetic resonance imaging (MRI), open new possibilities for medical imaging, e.g., in the fields of diagnostics or tissue characterization in regenerative medicine. The focus of this study is on the synthesis and characterization

• nanoparticles; magnetic resonance imaging (MRI); multifunctional nanoparticles; multimodal imaging; photoluminescence; Introduction In recent years, medical imaging has become an important approach in the fields of diagnostics, therapy and regenerative medicine. Besides the classical technology of X-ray

Nano-engineered skin mesenchymal stem cells: potential vehicles for tumour-targeted quantum-dot delivery

• Liga Saulite,
• Dominyka Dapkute,
• Karlis Pleiko,
• Ineta Popena,
• Simona Steponkiene,
• Ricardas Rotomskis and
• Una Riekstina

Beilstein J. Nanotechnol. 2017, 8, 1218–1230, doi:10.3762/bjnano.8.123

• QDs indicate their great potential in cancer diagnostics. The photoluminescence spectrum of carboxyl QD655 makes them ideal candidates for cancer theranostics as it overlaps with the optical transparency window of biological tissue [11]. Additionally, large and easily altered surfaces facilitate

• modifications increase the potential of QDs for the use in targeted cancer diagnostics and therapies. There is still doubt regarding the potential harmful effects of NPs or QDs on the differentiation capacity and self-renewal ability of adult stem cells. CdSe/ZnS QD labelling has been reported to adversely

α-((4-Cyanobenzoyl)oxy)-ω-methyl poly(ethylene glycol): a new stabilizer for silver nanoparticles

• Jana Lutze,
• Miguel A. Bañares,
• Marcos Pita,
• Andrea Haase,
• Andreas Luch and
• Andreas Taubert

Beilstein J. Nanotechnol. 2017, 8, 627–635, doi:10.3762/bjnano.8.67

• in, e.g., electronics or medicine [1][2][3]. Metallic nanoparticles intended for use in medicine or diagnostics are generally modified with an organic coating designed to prevent or at least to reduce aggregation in aqueous media [4][5][6][7][8][9][10][11][12][13]. A good stabilizing agent is thus

• , Zhang et al. [25] demonstrated the passivating effect of a PEG/silica hybrid coating on CdSe quantum dots. Thus, there is a growing interest in PEG-based stabilizers for a large variety of applications including catalysis, diagnostics, biology or biomedicine. There are numerous examples in which the

• the nanoparticle dispersion. The new polymeric stabilizer CBAmPEG may thus be interesting for application in biology, medicine, or diagnostics. A) 1H NMR spectrum, B) magnified view of the NMR signals, C) overview FTIR spectrum, and D) detailed view of the spectral region with the most intense signals

Streptavidin-coated gold nanoparticles: critical role of oligonucleotides on stability and fractal aggregation

• Roberta D'Agata,
• Pasquale Palladino and
• Giuseppe Spoto

Beilstein J. Nanotechnol. 2017, 8, 1–11, doi:10.3762/bjnano.8.1

• Andrea Doria 6, I-95125, Catania, Italy 10.3762/bjnano.8.1 Abstract Gold nanoparticles (AuNPs) exhibit unique properties that can be modulated through a tailored surface functionalization, enabling their targeted use in biochemical sensing and medical diagnostics. In particular, streptavidin-modified

• innovative diagnostic approaches we believe that these results will directly impact the ability to produce more reliable and sensitive nanoparticle-based diagnostics assays which could lead to advanced applications in nanomedicine which benefit of the ultrasensitive detection of nucleic acids. In addition

Graphene-enhanced plasmonic nanohole arrays for environmental sensing in aqueous samples

• Christa Genslein,
• Peter Hausler,
• Eva-Maria Kirchner,
• Rudolf Bierl,
• Antje J. Baeumner and
• Thomas Hirsch

Beilstein J. Nanotechnol. 2016, 7, 1564–1573, doi:10.3762/bjnano.7.150

• detection limits in the environmental interesting concentration is important for water safety and direly needed. Surface plasmon resonance spectroscopy (SPR) is a widely-used technique for quantifying and characterizing biomolecular interactions in biosensors for medical diagnostics, food safety and